Restoration of GABA_(B) receptor expression in cerebral ischemia:a promising novel neuroprotective strategy

作     者：Musadiq A.Bhat Mohammad Hleihil Dietmar Benke Musadiq A.Bhat;Mohammad Hleihil;Dietmar Benke

作者机构：Institute of Pharmacology and ToxicologyUniversity of ZurichZurichSwitzerland 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2023年第18卷第12期

页      面：2659-2660页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

基　　金：the Swiss National Science Foundation (grants 31003A_156648 and 31003A_182325 to DB) the Foundation for Research in Science and the Humanities at the University of Zurich (grant STWF-18-005 to DB) 

主　　题：cerebral ischemia death 

摘      要：Although stroke is a major global health problem, a pharmacological treatment to inhibit ongoing neuronal death in patients is still lacking. In cerebral ischemia, the prevailing form of stroke, severely reduced blood supply by obstruction of blood vessels deprives neurons from oxygen and glucose, eventually leading to metabolic derailment and death of neurons in the affected brain area.