2-取代苯并噁唑衍生物的合成及生物活性

作     者：钟滨 范志金 李正名 

作者机构：南开大学 

出 版 物：《应用化学》 (Chinese Journal of Applied Chemistry)

年 卷 期：2003年第20卷第7期

页      面：684-686页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：国家"八六三"项目 ( 2 0 0 1AA2 3 5 0 11)资助课题和教育部南开大学 天津大学科技合作基金资助 

主　　题：巯基苯并噁唑 合成 生物活性 

摘      要：Mercapto benzoxazole reacted with alkyl halide or N-substituted-2-chloroacetamides gave corresponding 2-alkylthiobenzoxazoles(2a～2h) and benzoxazole-2-ylthio-acetanilides (3a～3g) respectively. The structures of all the above compounds were confirmed by 1H NMR, IR and elemental analysis. Results showed that only compound 2g exhibited favorable fungicidal activity against Puccinia triticina(90%) in vivo at dosage of 500 mg/L; compounds 3a～3g exhibited inhibitory activity to Echinochloa oryzicola V and Brassica campestris L at the dosage of 150 mg/m 2.