The development of Terminalia chebula Retz.(Combretaceae) in clinical research

作     者：Anwesa Bag Subir Kumar Bhattacharyya Rabi Ranjan Chattopadhyay 

作者机构：Agricultural and Ecological Research UnitIndian Statistical Institute 203 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2013年第3卷第3期

页      面：244-252页

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 10[医学] 100602[医学-中西医结合临床] 

基　　金：Supported by Indian Statistical Institute Kolkata India(GrantNo Project A/C No.5613) 

主　　题：Terminalia chebula Human diseases Medicinal value Bioactive constituents Safety evaluation 

摘      要：Medicinal plants are part and parcel of human society to combat diseases from the dawn of *** chebula Retz.(***),is called the‘King of Medicine??in Tibet and is always listed at the lop of the list of‘Ayurvedic Materia Medica??because of its extraordinary power of *** whole plant possesses high medicinal value and traditionally used for the treatment of various ailments for human *** of the folklore people used this plant in the treatment of asthma,sore throat,vomiting,hiccough,diarrhea,dysentery,bleeding piles,ulcers,gout,heart and bladder *** plant has been demonstrated to possess multiple pharmacological and medicinal activities,such as antioxidant,antimicrobial,antidiabetic,hepatoprotective,anti-inflammatory,antimutagenic,antiproliferative,radioprotective,cardioprotective,antiarthritic,anticaries,gastrointestinal motility and wound healing *** no systematic updated information on the therapeutic effectiveness of Terminalia chebula,a popular herbal remedy in India and South-East Asia has so far been *** review highlights an updated information particularly on the phytochemistry and various pharmacological and medicinal properties of Terminalia chebula *** some of its isolated compounds,along with their safety *** may provide incentive for proper evaluation of the plant as medicinal agent against the human diseases and also to bridge the lacunae in the existing literature and future scope which may offer immense opportunity for researchers engaged in validation of the traditional claims and development of safe and effective botanical medicine.