Self-Navigated 3D Acoustic Tweezers in Complex Media Based on Time Reversal

作     者：Ye Yang Teng Ma Sinan Li Qi Zhang Jiqing Huang Yifei Liu Jianwei Zhuang Yongchuan Li Xuemin Du Lili Niu Yang Xiao Congzhi Wang Feiyan Cai Hairong Zheng 

作者机构：Paul C.Lauterbur Research Center for Biomedical ImagingKey Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong ProvinceShenzhen Key Laboratory of Ultrasound Imaging and TherapyShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Shenzhen College of Advanced TechnologyUniversity of the Chinese Academy of SciencesBeijing 100049China VerasonicsInc.WA 98034USA 

出 版 物：《Research》 (研究（英文）)

年 卷 期：2021年第2021卷第1期

页      面：801-813页

核心收录：

学科分类：07[理学] 082403[工学-水声工程] 08[工学] 070206[理学-声学] 0824[工学-船舶与海洋工程] 0702[理学-物理学] 

基　　金：supported in part by the National Natural Science Foundation of China Grant(Grant Nos.81527901,61571431,11774370,81827807,and 81827802) Shenzhen Peacock Plan(Grant No.KQTD20170810160424889) Scientific Instruments Funding of Chinese Academy of Sciences(Grant No.YJKYYQ20190077) Shenzhen Key Laboratory of ultrasound imaging and therapy(Grant No.ZDSYS20180206180631473) 

主　　题：thereby transparency precise 

摘      要：Acoustic tweezers have great application prospects because they allow noncontact and noninvasive manipulation of microparticles in a wide range of ***,the nontransparency and heterogeneity of media in practical applications complicate particle trapping and *** this study,we designed a 1.04 MHz 256-element 2D matrix array for 3D acoustic tweezers to guide and monitor the entire process using real-time 3D ultrasonic images,thereby enabling acoustic manipulation in nontransparent ***,we successfully performed dynamic 3D manipulations on multiple microparticles using multifoci and vortex *** achieved 3D particle manipulation in heterogeneous media(through resin baffle and ex vivo macaque and human skulls)by introducing a method based on the time reversal principle to correct the phase and amplitude distortions of the acoustic *** results suggest cutting-edge applications of acoustic tweezers such as acoustical drug delivery,controlled micromachine transfer,and precise treatment.