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Integrated zoology’s collection of Wildlife Diseases Research Network

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Integrative zoology 2024年第3期19卷 348-349页

作者： Wenhua XIONG institute of zoology Chinese Academy of Sciences Office of the International Society of Zoological Sciences

The International Society of Zoological Sciences has developed a Wildlife Diseases Research Network(WDRN)in the world,with the collaboration of its partners such as the Working Group on Zoonotic Disease of the International Union of Biological Sciences(IUBS)(https://***/).WDRN is composed of a steering committee,a scientific committee,a research expert network,and collaborative partners.

关键词： partner committee IUB

Challenges confronting spider taxonomy in Asia

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Zoological Systematics 2024年第1期49卷 1-3页

作者： Shuqiang Li Yejie Lin institute of zoology Chinese Academy of SciencesBeijing 100101China

As the largest continent in the world,bound by the Pacific,Indian,and Arctic Oceans and the Mediterranean Sea,Asia is well-endowed in its geological and biological *** surprisingly,spiders abound in the vast expanses of its tropic and temperate forests,lofty mountain ranges and plateaus,and flood plains of its many river ***,it is only over the past two decades that we have begun to make a concerted effort to undertake the study of spider taxonomy,and correspondingly,to discuss the issue of conservation of their habitats.

关键词： flood Arctic plateau

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Genome editing in plants using the TnpB transposase system

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aBIOTECH 2024年第2期5卷 225-230页

作者： Qi Li Yongqiang Wang Zhuoting Hou Hang Zong Xuping Wang Yong EZhang Haoyi Wang Haitao Chen Wen Wang Kang Duan School of Ecology and Environment Northwestern Polytechnical UniversityXi’an 710129China Sanjie institute of Forage Yangling 712100China Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China

The widely used clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated nuclease(Cas)system is thought to have evolved from IS200/IS605 *** proteins,encoded by one type of IS200/IS605 transposon,are considered to be the evolutionary ancestors of Cas12 nucleases,which have been engineered to function as RNA-guided DNA endonucleases for genome editing in bacteria and human *** nucleases,which are smaller than Cas nucleases,have been engineered for use in genome editing in animal systems,but the feasibility of this approach in plants remained ***,we obtained stably transformed genome-edited mutants in rice(Oryza sativa)by adapting three recently identified TnpB genome editing vectors,encoding distinct TnpB nucleases(ISAam1,ISDra2,and ISYmu1),for use in plants,demonstrating that the hypercompact TnpB proteins can effectively edit plant ***2 and ISYmu1 precisely edited their target sequences,with no off-target mutations detected,showing that TnpB transposon nucleases are suitable for development into a new genome editing tool for *** modifications improving the genome-editing efficiency of the TnpB system will facilitate plant functional studies and breeding programs.

关键词： ISAam1 ISDra2 ISYmu1 Plant genome editing Rice TnpB transposon endonuclease

Illuminating functions of evolutionarily conserved long non-coding RNAs

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Science China Life Sciences 2024年第9期67卷 2043-2044页

作者： Ruiqiao He Fangqing Zhao institute of zoology Chinese Academy of Sciences Key Laboratory of Systems Health Science of Zhejiang Province Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences

Long non-coding RNAs(lnc RNAs) serve as crucial regulators of gene expression,influencing various physiological processes and disease states(Cabili et al.,2011; Ulitsky and Bartel, 2013; Yao et al.,2019). Dysregulation of certain notable lnc RNAs, such as HOTAIR and MALAT1,has been implicated in a wide range of pathological processes, including tumorigenesis in various human cancers(Gupta et al., 2010; Kim et al., 2018). However,the functions of the majority of lnc RNAs remain elusive.

关键词： LINCRNAS

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Impact of letters to the editor and publications in 2023

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Zoological Research 2024年第1期45卷 136-137页

作者： Xiu-Ping Zhang Xue-Long Jiang Yong-Gang Yao Editorial Office of ZR&ZRDC Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China

A letter to the editor constitutes a short communication addressing a range of topics pertinent to the readership of a journal(Dkhar,2018).This format offers several benefits,such as timeliness,accessibility,innovation,and conciseness,thereby serving as an effective means to disseminate cuttingedge scientific *** the past five years,there has been a considerable increase in the number of letters published,representing the highest growth rate(approximately 20%)observed in the last three decades(Figure 1A).In the field of academic publishing,letters to the editor are typically more concise than typical research papers.

关键词： journal editor Figure

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Molecular mechanism of nanomaterials induced liver injury:A review

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World Journal of Hepatology 2024年第4期16卷 566-600页

作者： Sanjib Kumar Das Koushik Sen Biswatosh Ghosh Nabanita Ghosh Krishnendu Sinha Parames C Sil Department of zoology Jhargram Raj CollegeJhargram 721507India Department of zoology Bidhannagar CollegeKolkata 700064India Department of zoology Maulana Azad CollegeKolkata 700013India Department of Molecular Medicine Bose InstituteCalcutta 700054India

The unique physicochemical properties inherent to nanoscale materials have unveiled numerous potential applications,spanning beyond the pharmaceutical and medical sectors into various consumer industries like food and ***,humans encounter nanomaterials through diverse exposure routes,giving rise to potential health *** among these materials are silica and specific metallic nanoparticles,extensively utilized in consumer products,which have garnered substantial attention due to their propensity to accumulate and induce adverse effects in the *** review paper aims to provide an exhaustive examination of the molecular mechanisms underpinning nanomaterial-induced hepatotoxicity,drawing insights from both in vitro and in vivo ***,the most frequently observed manifestations of toxicity following the exposure of cells or animal models to various nanomaterials involve the initiation of oxidative stress and ***,we delve into the existing in vitro models employed for evaluating the hepatotoxic effects of nanomaterials,emphasizing the persistent endeavors to advance and bolster the reliability of these models for nanotoxicology research.

关键词： Nanoparticles Hepatotoxicity Oxidative stress Inflammation Autophagy

Matrix metalloproteinase 2 contributes to adult eclosion and immune response in the small hive beetle,Aethina tumida

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Insect Science 2024年第3期31卷 733-747页

作者： Lixian Wu Yajing Xu Liangbin Li Dainan Cao Fang Liu Hongxia Zhao Guangdong Key Laboratssory of Animal Conservation and Resource Utilization Guangdong Public Laboratory of Wild Animal Conservation and UtilizationInstitute of ZoologyGuangdong Academy of SciencesGuangzhouChina

During the pupal-adult eclosion process of holometabolous insects,the old cuticle is shed and replaced by a completely different new cuticle that requires tanning and expansion,along with extensive extracellular matrix(ECM)*** vertebrates,matrix metalloproteinases(MMPs),a class of zinc-dependent endopeptidases,play key roles in regulating the ECM that surrounds ***,little is known about these extracellular proteinases available in *** small hive beetle(SHB),Aethina tumida,is a widespread invasive parasite of honey *** this study,6 MMP homologs were identified in the SHB *** interference experiments showed that all 6 AtMmps are not required for the larval-pupal transition,only AtMmp2 was essential for pupal-adult eclosion in *** of AtMmp2 resulted in eclosion defects and wing expansion failure,as well as mortality within 3 d of adult *** analysis revealed that knockdown of AtMmp2 significantly increased expression of the Toll and Imd pathways,chitin metabolism,and cross-linking(such as the pro-phenoloxidase activating cascade pathway and the tyrosine-mediated cuticle sclerotization and pigmentation pathway).These data revealed evolutionarily conserved functions of Mmp2 in controlling adult eclosion and wing expansion,also provided a preliminary exploration of the novel function of regulating Toll and Imd pathways,as well as new insights into how MMPs regulate insect development and defense barriers.

关键词： Aethina tumida adult eclosion immune response matrix metalloproteinase RNAinterference

One-step cell biomanufacturing platform:porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo

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Neural Regeneration Research 2024年第2期19卷 458-464页

作者： Lin Feng Da Li Yao Tian Chengshun Zhao Yun Sun Xiaolong Kou Jun Wu Liu Wang Qi Gu Wei Li Jie Hao Baoyang Hu Yukai Wang State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina institute for Stem Cell and Regenerative Medicine Chinese Academy of SciencesBeijingChina National Stem Cell Resource Center Chinese Academy of SciencesBeijingChina Savaid Medical School University of Chinese Academy of SciencesBeijingChina Beijing institute for Stem Cell and Regenerative Medicine BeijingChina State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina

Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s *** of midbrain dopaminergic progenitor cells is a promising treatment for Parkinson’s ***,transplanted cells can be injured by mechanical damage during handling and by changes in the transplantation ***,we developed a one-step biomanufacturing platform that uses small-aperture gelatin microcarriers to produce beads carrying midbrain dopaminergic progenitor *** beads allow midbrain dopaminergic progenitor cell differentiation and cryopreservation without digestion,effectively maintaining axonal integrity in ***,midbrain dopaminergic progenitor cell bead grafts showed increased survival and only mild immunoreactivity in vivo compared with suspended midbrain dopaminergic progenitor cell ***,our findings show that these midbrain dopaminergic progenitor cell beads enhance the effectiveness of neuronal cell transplantation.

关键词： axonal integrity cell cryopreservation cellular environment cellular niche cell replacement therapy dopaminergic progenitors human pluripotent stem cell mechanical damage neuronal cell delivery Parkinson’s disease small-aperture gelatin microcarriers

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Rapid growth in a large Cambrian apex predator

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National Science Review 2024年第3期11卷 128-136页

作者：吴雨 Stephen Pates Daniel Pauly 张兴亮傅东静 State Key Laboratory of Continental Dynamics and Shaanxi Key Laboratory of Early Life and Environment Department of Geology Northwest University Department of zoology University of Cambridge institute for the Oceans and Fisheries University of British Columbia Nanjing institute of Geology and Palaeontology Chinese Academy of Sciences

Despite the importance of ontogenetic data on early diverging euarthropods to our understanding of the ecology and evolution of past life, the data are distinctly lacking, as reconstructing life histories of fossil animals is often challenging. Here we report the growth trajectory of frontal appendages of the apex predator Amplectobelua symbrachiata, one of the most common radiodont arthropods from the early Cambrian Chengjiang biota(c. 520 Ma) of China. Analysis of 432 specimens(9.1–137.1 mm length; 1.3–25.6 mm height) reveals that appendages grew isometrically, with an estimated maximum size of the whole animal of c. 90 cm. Individuals grew rapidly compared to extant arthropods, as assessed using the electronic length-frequency analysis(ELEFAN) approach. Therefore, we show that the Cambrian apex predator A. symbrachiata was an extremely fast-growing arthropod, with an unusual life history strategy that formed as part of the escalatory ‘arms race’ that shaped the Cambrian explosion over 500 Ma.

关键词： stem-group Euarthropoda Radiodonta post-embryonic development growth dynamics Cambrian Explosion