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Application of multidisciplinary team-based integrated traditional chinese medicine and Western medicine in rotator cuff injury patients undergoing arthroscopic surgery

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World Journal of Clinical Cases 2024年第19期12卷 3767-3775页

作者： Di-Ping Cao Lei Yin Yi-Fei Wang Bing-Li Liu Department of Orthopedics The Seventh People's Hospital of Shanghai University of Traditional Chinese MedicineShanghai 200137China

BACKGROUND Arthroscopic rotator cuff repair is a common surgical treatment for rotator cuff injuries(RCIs).Although this procedure has certain clinical advantages,it requires rehabilitation management interventions to ensure therapeutic *** To investigate the effect of integrated traditional chinese medicine and Western medicine(TCM-WM)under the multidisciplinary team(MDT)model on the postoperative recovery of patients undergoing arthroscopic surgery for *** This study enrolled 100 patients who underwent arthroscopic rotator cuff repair for RCIs at the Seventh People’s Hospital of Shanghai University of traditional chinese medicine between June 2021 and May *** were divided into a control group(n=48)that received routine rehabilitation treatment and an experimental group(n=52)that received TCM-WM under the MDT model(e.g.,acupuncture,TCM traumatology and orthopedics,and rehabilitation).The results of the Constant–Murley Shoulder Score(CMS),Visual Analogue Scale(VAS),Shoulder Pain and Disability Index(SPADI),muscular strength evaluation,and shoulder range of motion(ROM)assessments were *** After treatment,the experimental group showed significantly higher CMS scores in terms of pain,functional activity,shoulder joint mobility,and muscular strength than the baseline and those of the control *** experimental group also exhibited significantly lower VAS and SPADI scores than the baseline and those of the control *** addition,the experimental group showed significantly enhanced muscular strength(forward flexor and external and internal rotator muscles)and shoulder ROM(forward flexion,abduction,and lateral abduction)after treatment compared with the control *** TCM-WM under the MDT model improved shoulder joint function,relieved postoperative pain,promoted postoperative functional recovery,and facilitated the recovery of muscular strength and shoulder ROM in patients with RCIs who underwent arthroscopic rotator c

关键词： Multidisciplinary team model Integrated traditional chinese medicine and Western medicine Rotator cuff injury Arthroscopy Arthroscopic surgery

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Individualized traditional chinese medicine treatment vs antibiotics for recurrent urinary tract infections: a multicenter, randomized controlled study

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Journal of traditional chinese medicine 2024年第3期44卷 524-529页

作者： GU Xiangchen QIU Meisi XIE Lin CHEN Min DENG Yueyi ZHANG Changming JIAN Guihua WANG Chen WANG Yi Department of Nephrology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine Department of Nephrology Rizhao Hospital of Traditional Chinese Medicine Department of Nephrology Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Department of Nephrology Shanghai Municipal Traditional Chinese Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Department of Nephrology the Sixth People's Hospital Affiliated Shanghai Jiaotong University Department of Nephrology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

OBJECTIVE: To systematically assess the effects of individualized chinese medicines on recurrent urinary tract infections(rUTIs).METHODS: This study recruited 230 adult female patients in the remission phase of rUTIs from five hospitals in China. The patients were randomly allocated to two groups: an individualized chinese medicine group(n = 114) and a control group(n = 116). Patients in the chinese medicine group received individualized chinese herbs, which were evaluated for syndrome *** in the control group received antibiotic treatment combined with a chinese medicine placebo. The duration of treatment was three courses of four weeks each, with a three-month subsequent follow-up. UTI recurrence rate,traditional chinese medicine(TCM) syndrome scores,36-item Short Form Survey(SF-36) score, and urine secretory immunoglobulin A(SIgA) were measured and analyzed before and after treatment in each group. RESULTS: Patients from the chinese medicine group exhibited significant decreases in both short-and longterm UTI recurrence rates compared with the control group(P chinese medicine and control groups were significant(P chinese medicine group were also significantly higher than those in the control group after treatment(P chinese medicine group also demonstrated a significant increase in urine SIg A expression. CONCLUSION: Taken together, compared to the oftenused long-term antimicrobial prophylaxis during the remission stage of r UTIs, treating patients with an individualized chinese medicine decoction by syndrome differentiation could effectively reduce the recurrence rate, improve the patients' TCM syndrome scores and quality of life, and enhance immunity, which in turn helps to prevent antibiotic resistance.

关键词： immunoglobulin A, secretory medicine, chinese traditional quality of life randomized controlled trial syndrome differentiation urinary tract infections

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Organic Integration of traditional chinese and Western medicines—Future of Clinical Practice Guidelines of Integrated traditional chinese and Western medicines

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chinese Journal of Integrative medicine 2024年第4期30卷 359-365页

作者： XIE Ying-lan HAN Fei JIN Ying-hui DING Yan-bing GUO Jing JI Dong-xiao ZHANG Teng CHENXiao-min SHANG Hong-cai Department of traditional chinese medicine Encephalopathy Hubei Provincial Hospital of Traditional Chinese MedicineWuhan(430074)China Department of traditional chinese medicine Encephalopathy Hubei Province Traditional Chinese Medicine Research InstituteWuhan(430074)China Xuanwu Hospital of traditional chinese medicine Beijing(100000)China Center for Evidence-Based and Translational medicine Zhongnan Hospital of Wuhan UniversityWuhan(430074)China College of Acupuncture and Massage College of Health and RehabilitationNanjing University of Chinese MedicineNanjing(210023)China Department of Ophthalmology Huaihe Hospital of Henan UniversityKaifengHenan Province(475000)China Ministry of Education and Beijing Key Laboratory of Internal medicine of traditional chinese medicine Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine/Ministry of Education and Beijing Key Laboratory of Internal Medicine of Traditional Chinese MedicineBeijing(100700)China

The transformation and implementation of clinical practice guidelines for integrated traditional chinese medicine(TCM)and Western medicine(WM)is crucial to the adoption of medical science and technological findings and is an important way for TCM to be made available to the ***,clinical practice guidelines(CPGs)of TCM and WM integration in recent years was analyzed to clarify the current situation and problems in the existing guidelines according to the following four perspectives:(1)perspective of TCM and WM integration in guidelines,(2)diagnosis Using integrated TCM and WM,(3)integration of TCM and WM treatment,(4)promoting TCM and WM ***,the information and quality evaluation of CPGs for integrated chinese and Western medicine in 2020–2022 were analyzed to explore the degree and methods of integration of chinese and Western medicine *** last this study aimed to lay a foundation for the further establishment of chinese characteristic,repeatable,and calculable clinical practice guidelines of TCM and WM integration.

关键词： clinical practice guidelines integrated traditional chinese and Western medicine organic integration

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From ancient wisdom to modern science:Gut microbiota sheds light on property theory of traditional chinese medicine

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Journal of Integrative medicine 2024年第4期22卷 413-444页

作者： Ya-nan Yang Jia-guo Zhan Ying Cao Chong-ming Wu School of chinese Materia Medica Tianjin University of Traditional Chinese MedicineTianjin 301617China Tianjin Key Laboratory of Therapeutic Substance of traditional chinese medicine Tianjin 301617China

The property theory of traditional chinese medicine(TCM) has been practiced for thousands of years,playing a pivotal role in the clinical application of TCM. While advancements in energy metabolism,chemical composition analysis, machine learning, ion current modeling, and supercritical fluid technology have provided valuable insight into how aspects of TCM property theory may be measured, these studies only capture specific aspects of TCM property theory in isolation, overlooking the holistic perspective inherent in TCM. To systematically investigate the modern interpretation of the TCM property theory from multidimensional perspectives, we consulted the chinese Pharmacopoeia(2020 edition) to compile a list of chinese materia medica(CMM). Then, using the Latin names of each CMM and gut microbiota as keywords, we searched the PubMed database for relevant research on gut microbiota and CMM. The regulatory patterns of different herbs on gut microbiota were then summarized from the perspectives of the four natures, the five flavors and the meridian tropism. In terms of the four natures, we found that warm-natured medicines promoted the colonization of specific beneficial bacteria,while cold-natured medicines boosted populations of some beneficial bacteria while suppressing pathogenic bacteria. Analysis of the five flavors revealed that sweet-flavored and bitter-flavored CMMs positively influenced beneficial bacteria while inhibiting harmful bacteria. CMMs with different meridian tropism exhibited complex modulative patterns on gut microbiota, with Jueyin(Liver) and Taiyin(Lung) meridian CMMs generally exerting a stronger effect. The gut microbiota may be a biological indicator for characterizing the TCM property theory, which not only enhances our understanding of classic TCM theory but also contributes to its scientific advancement and application in healthcare.

关键词： traditional chinese medicine Property theory Gut microbiota Four natures Five flavors Meridian tropism

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The combination of gut microbiota-depleted treatment and fecal microbiota transplantation is an important strategy to verify the efficacy of traditional chinese medicine though modulation of gut dysbiosis

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Journal of traditional chinese medicine 2024年第1期44卷 222-223页

作者： XING Yunqi LI Junxiang YUAN Yali MAO Tangyou Gastroenterology Department Dongfang HospitalBeijing University of Chinese MedicineBeijing 100078China Department of Hepatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 201203China

To the Editors:We read with great interest the study recently published by Sun et al 1 entitled“Electroacupuncture at Tianshu(ST25)and Zusanli(ST36)alleviates stress-induced irritable bowel syndrome in mice by modulating gut microbiota and corticotropin-releasing factor”in which the microbial details of electroacupuncture(EA)-induced protection in irritable bowel syndrome(IBS)were investigated.

关键词： releasing treatment details

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International standard of traditional chinese medicine techniques: the operating specifications for chinese medicated bath(2022)

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Journal of traditional chinese medicine 2024年第4期44卷 851-854页

作者： ZHANG Jing WANG Chunhui JIN Xinyan YU Miao FAN Yingyi HAN Xiaoli PEI Xiaohua Department of dermatology Beijing University of Chinese Medicine Third Affiliated Hospital Department of Chest and Breast surgery Beijing University of Chinese Medicine Xiamen Hospital Center for Evidence-Based medicine Beijing University of Chinese Medicine Department of General surgery Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University Department of Breast surgery Beijing University of Chinese Medicine Third Affiliated Hospital

chinese medicated bath is one of the external therapies in traditional chinese medicine(TCM), which has been widely used clinically. The “International Standard of traditional chinese medicine Techniques: The Operating Specifications for chinese Medicated Bath” is drawn up by the Beijing University of chinese medicine Third Affiliated Hospital and Beijing University of chinese medicine Xiamen Hospital in collaboration with domestic TCM universities and hospitals. The specification includes definition, operating process, points for attention and contraindications. It is targeted to provide reference for TCM providers at home and abroad with TCM background in clinical decision-making.

关键词： chinese medicated bath international standard operating specifications traditional chinese medical technology

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A real-world study of the differences in traditional chinese medicine diagnosis and treatment rules for coronavirus disease 2019 between Northern and Southern China

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Journal of traditional chinese medicine 2024年第4期44卷 822-829页

作者： SU Rui SU Youzhu WANG Shuo FAN Jie LIU Qingquan LIU Mifeng Department of infectious diseases Capital Medical University Beijing Hospital of Traditional Chinese Medicine

OBJECTIVE: To explore the differences in traditional chinese medicine(TCM) diagnosis and treatment rules for coronavirus disease 2019(COVID-19) between Northern and Southern China based on the real-world data from 982 COVID-19 patients. METHODS: All consecutive cases of COVID-19 admitted to the TCM department of designated COVID-19 hospitals in eight provinces and cities were retrospectively analyzed. Patients were divided into a Northern and a Southern group according to the location of the admitting hospital. The symptoms, syndrome elements, syndrome distribution and herbal treatments were analyzed. The core prescriptions were extracted using the multiscale backbone-based network comparison algorithm(msbNC). RESULTS: The distribution of syndrome elements showed that dampness was common in Northern and Southern China, wind and heat were more often present in the South, while fire toxin and spleen deficiency were more often encountered in the North. The distribution of syndromes showed that the South was dominated by heat dampness accumulating in the lung(55.69%), while the North was dominated by dampness-toxin stagnating in the lung(44.90%).The results of core prescription mining showed that dispelling dampness, dispersing wind, clearing heat and strengthening spleen were the common treatment methods in Northern and Southern China. For mild cases, Jinyinhua(Flos Lonicerae) and Lianqiao(Fructus Forsythiae Suspensae) were often used in the South to clear heat and relieve exterior symptoms, while Chaihu(Radix Bupleuri Chinensis) and Huangqin(Radix Scutellariae Baicalensis) were often used in the North to relieve muscles by expelling heat. For moderate cases, Chaihu(Radix Bupleuri Chinensis), Qinghao(Herba Artemisiae Annuae), and Shigao(Gypsum Fibrosum) were often used to clear heat of Tri-jiao Channel and stomach in the South, while Fuling(Poria), Chenpi(Pericarpium Citri Reticulatae), and Dangshen(Radix Codonopsis) were often used to invigorate spleen and remove damp

关键词： COVID-19 North-South difference core prescription medicine, chinese traditional retrospective studies syndrome

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International Standard of traditional chinese medicine Techniques: The Operating Specification for traditional chinese medicine Enema(2022)

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Journal of traditional chinese medicine 2024年

作者： YU Miao PEI Xiaohua Department of General surgery Beijing Hospital of traditional chinese medicine Affiliated to Capital Medical University Department of Chest and Breast surgery Beijing University of chinese medicine Xiamen Hospital

chinese medicine Enema is one of the external therapies in traditional chinese medicine (TCM)， which has been widely used clinically. The “International Standard of traditional chinese medicine Techniques: The Operating Specifications for chinese medicine Enema is drawn up by the Beijing Hospital of traditional chinese medicine Affiliated to Capital Medical University and Beijing University of chinese medicine Xiamen Hospital in collaboration with domestic TCM universities and hospitals. The specification includes definition， operating process， points for attention and contraindications. It is targeted to provide reference for TCM providers at home and abroad with TCM background in clinical decision-making.

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Kuicolong-yu enema decoction retains traditional chinese medicine enema attenuates inflammatory response ulcerative colitis through TLR4/NF-κB signaling pathway

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World Journal of Gastrointestinal surgery 2024年第4期16卷 1149-1154页

作者： Li Han Kun Tang Xiao-Li Fang Jing-Xi Xu Xi-Yun Mao Ming Li Department of Anorectal Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Anhui HospitalHefei 230001Anhui ProvinceChina Anorectal Center The First Affiliated Hospital of Anhui University of Traditional Chinese MedicineHefei 230001Anhui ProvinceChina Department of Spleen and Stomach Diseases Department of GastroenterologyAffiliated Wuhu Hospital of Traditional Chinese Medicine of Anhui College of Traditional Chinese MedicineWuhu 241000Anhui ProvinceChina

BACKGROUND Ulcer colitis(UC)is a chronic,nonspecific,and noninfectious inflammatory bowel ***,Toll-like receptors(TLRs)have been found to be closely associated with clinical inflammatory *** complete remission in patients with intermittent periods of activity followed by dormancy is ***,no study has explored the mechanism by which Kuicolong-yu enema decoction retains traditional chinese medicine enemas to attenuate the inflammatory response in *** To explore the mechanism by which Kuicolong-yu enema decoction retains traditional chinese medicine enemas to attenuate the inflammatory response in *** This prospective clinical study included patients who met the exclusion criteria in 2020 and *** patients with UC were divided into two groups(control and experimental).The peripheral blood of the experimental and control groups were collected under aseptic *** expression of TLR4 protein,NF-κB,IL-6,and IL-17 was detected in the peripheral blood of patients in the experimental group and control group before and 1 month after taking the *** co rrelation analysis was used to analyze the relationship between the expression level of TLR4 protein and the expression levels of downstream signal NF-κB and inflammatory factors IL-6 and IL-17,and P<0.05 was considered statistically *** There were no significant differences in the patient characteristics between the control and experimental *** results showed that the expression levels of TLR4 and NF-κB in the experimental group were significantly lower than those in the control group(P<0.05).The levels of IL-6 and IL-17 in the experimental group were significantly lower than those in the control group(P<0.05).The TLR4 protein expression in the experimental group was positively correlated with the expression level of downstream signal NF-κB and was positively correlated with the levels of downstream inflammatory cytokines IL-6 and IL-

关键词： Ulcerative colitis TLR4 NF-κB signaling pathway Kuicolong-yu enema

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Knee osteoarthritis:A review of animal models and intervention of traditional chinese medicine

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Animal Models and Experimental medicine 2024年第2期7卷 114-126页

作者： Xuyu Song Ying Liu Siyi Chen Lei Zhang Huijie Zhang Xianhui Shen Hang Du Rong Sun Orthopaedic trauma surgery The Second Hospital of Shandong UniversityJinanShandongChina Academy of traditional chinese medicine Tianjin University of Traditional Chinese MedicineTianjinChina Department of traditional chinese medicine The Second Hospital of Shandong UniversityJinanShandongChina College of pharmacy Shandong University of Traditional Chinese MedicineJinanShandongChina The Second Clinical College of Shandong University Shandong UniversityJinanShandongChina Advanced Medical Research Institute Shandong UniversityJinanShandongChina The Second Hospital of Shandong University JinanShandongChina

Background:Knee osteoarthritis(KOA)characterized by degeneration of knee cartilage and subsequent bone hyperplasia is a prevalent joint condition primarily affecting aging *** pathophysiology of KOA remains poorly understood,as it involves complex mechanisms that result in the same ***,researchers are interested in studying KOA and require appropriate animal models for basic *** herbal compounds,which consist of multiple herbs with diverse pharmacological properties,possess characteristics such as multicomponent,multipathway,and multitarget *** potential benefits in the treatment of KOA continue to attract ***:This study aims to provide a comprehensive overview of the advantages,limitations,and specific considerations in selecting different species and methods for KOA animal *** will help researchers make informed decisions when choosing an animal ***:Online academic databases(e.g.,PubMed,Google Scholar,Web of Science,and CNKI)were searched using the search terms“knee osteoarthritis,”“animal models,”“traditional chinese medicine,”and their combinations,primarily including KOA studies published from 2010 to ***:Based on literature retrieval,this review provides a comprehensive overview of the methods of establishing KOA animal models;introduces the current status of advantages and disadvantages of various animal models,including mice,rats,rabbits,dogs,and sheep/goats;and presents the current status of methods used to establish KOA animal ***:This study provides a review of the animal models used in recent KOA research,discusses the common modeling methods,and emphasizes the role of traditional chinese medicine compounds in the treatment of KOA.

关键词： animal models knee osteoarthritis system review traditional chinese medicine

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