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Food Science and Human Wellness 2024年第2期13卷 842-855页

作者： Qihong Jiang Lin Chen rui Wang Yin Chen Shanggui deng Guoxin Shen Shulai Liu Xingwei Xiang College of Food Science and technology Zhejiang University of TechnologyHangzhou 310014China Key Laboratory of Marine Fishery resources Exploitment&Utilization of Zhejiang Province Hangzhou 310014China national r&d Branch center for Pelagic Aquatic Products processing(Hangzhou) Hangzhou 310014China Institute of Sericultural and Tea Zhejiang Academy of Agricultural SciencesHangzhou 310021China College of Food and Pharmacy Zhejiang Ocean UniversityZhoushan 316000China

Type 2 diabetes mellitus(T2dM)is a complex metabolic disease threatening human *** investigated the effects of Tegillarca granosa polysaccharide(TGP)and determined its potential mechanisms in a mouse model of T2dM established through a high-fat diet and ***(5.1×10^(3) da)was composed of mannose,glucosamine,rhamnose,glucuronic acid,galactosamine,glucose,galactose,xylose,and *** could significantly alleviate weight loss,reduce fasting blood glucose levels,reverse dyslipidemia,reduce liver damage from oxidative stress,and improve insulin ***-PCr and Western blotting indicated that TGP could activate the phosphatidylinositol-3-kinase/protein kinase B signaling pathway to regulate disorders in glucolipid metabolism and improve insulin *** increased the abundance of Allobaculum,Akkermansia,and Bifidobacterium,restored the microbiota abundance in the intestinal tracts of mice with T2dM,and promoted short-chain fatty acid *** study provides new insights into the antidiabetic effects of TGP and highlights its potential as a natural hypoglycemic nutraceutical.

关键词： Tegillarca granosa polysaccharide Type 2 diabetes mellitus Glycolipid metabolism PI3K/Akt signaling pathway

Noncovalent cross-linked engineering hydrogel with low hysteresis and high sensitivity for flexible self-powered electronics

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Journal of Energy Chemistry 2024年第7期94卷 136-147页

作者： Hang Yuan Shaowei Han Jia Wei Songwei Li Peipei Yang Hao-Yang Mi Chuntai Liu Changyu Shen national Engineering research center for Advanced Polymer processing technology Key Laboratory of Materials Processing and Mold(Ministry of Education)Zhengzhou UniversityZhengzhou450002HenanChina Yunnan TobaccoQuality Inspection&Supervision Station Kunming 650106YunnanChina

In this study,the hydrogel network was reinforced by covalent-like hydrogen bonding,and the strong binding ability of boron-nitrogen coordination served as the main driving *** them,acrylamide(AM)and 3-acrylamidophenylboronic acid(AAPBA)were the main body,and the numerous hydroxyl groups in the trehalose(Treh)molecule and other polymer groups formed strong hydrogen bonding interactions to improve the mechanical properties of the PAM/PAAPBA/Treh(PAAT)hydrogel and ensured the simplicity of the synthesis *** hydrogel possessed high strain at break(1239%),stress(64.7 kPa),low hysteresis(100%to 500%strain,corresponding to dissipation energy from 1.37 to 7.80 kJ/m^(3)),and outstanding cycling stability(retained more than 90%of maximum stress after 200 ten-sile cycles).By integrating carbon nanotubes(CNTs)into PAAT hydrogel(PAATC),the PAATC hydrogel with excellent strain response performance was successfully *** PAATC conductive hydro-gel exhibited high sensitivity(gauge factor(GF)=10.58 and sensitivity(S)=0.304 kPa^(-1)),wide strain response range(0.5%-1000%),fast response time(450 ms),and short recovery time(350 ms),excellent fatigue resistance,and strain response ***,the PAATC-based triboelectric nanogener-ator(TENG)displayed outstanding energy harvesting performance,which shows its potential for appli-cation in self-powered electronic devices.

关键词： Low hysteresis Covalent-like hydrogen bonding Boron-nitrogen coordination Hydrogel sensor Triboelectric nanogenerator

Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing

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Food Science and Human Wellness 2024年第1期13卷 75-89页

作者： Xiaofei Wang Xiaowen Cheng Huiling Liu Xiaohuan Mu Hao Zheng national Engineering technology research center for Fruit and Vegetable processing Key Open Laboratory of Fruit and Vegetable ProcessingMinistry of Agriculture and Rural AffairsBeijing Key Laboratory of Food Non-Thermal ProcessingCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China

due to the complex natures of dietary food components,it is difficult to elucidate how the compounds affect host *** food often selectively presents its mechanism of action on different cell types,and participates in the modulation of targeted cells and their microenvironments within ***,the limitations of traditional in vitro assays or in vivo animal experiments cannot comprehensively examine cellular heterogeneity and the tissue-biased ***-cell rNA sequencing(sc rNA-seq)has emerged as an indispensable methodology to decompose tissues into different cell types for the demonstration of transcriptional profiles of individual *** rNA-seq applications has been summarized on three typical organs(brain,liver,kidney),and two representative immune-and tumor related health *** everincreasing role of sc rNA-seq in dietary food research with further improvement can provide sub-cellular information and the coupling between other cellular *** this review,we propose utilizing sc rNAseq to more effectively capture the subtle and complex effects of food chemicals,and how they may lead to health problems at single-cell *** novel technique will be valuable to elucidate the underlying mechanism of both the health benefits of food nutrients and the detrimental consequences food toxicants at the cellular level.

关键词： dietary food Cellular heterogeneity Single-cell rNA sequencing Food nutrients Food toxicants

A review:the mechanism of plant-derived polysaccharides on osteoblasts and osteoclasts

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未来食品学报(英文) 2024年第3期4卷 183-192页

作者： Mengjie ren Adel F.Ahmed Meng Li Menghan Li Zhiruo Yan Jinmei Wang national r&d center for Edible Fungus processing technology Henan UniversityKaifeng 475004China Joint International research Laboratory of Food&Medicine resource Function Henan ProvinceKaifeng 475004China Medicinal and Aromatic Plants researches department Horticulture Research InstituteAgricultural Research CenterGiza 12511Egypt

Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the *** and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts,exerting anti-osteoporosis *** to the previous research,the extract of Cibotium barumoz,Achyranthes bidentata,Curculigo orchioides,Epimedium brevicornum,Angelica sinensis,Polygonatum sibiricum,dendrobium officinale,Morinda officinalis,Nelumbo mucifera,diospyros kaki,Hordeum vulgare,Cistanche deserticola,Commiphora Myrrha and other plant-derived polysaccharides could benefit to the osteoblasts and *** essential mechanisms are mainly related to the activation or inhibition of many factors,including runt-related transcription factor 2(runx2),B-catenin,osterix(Osx),activator protein-1(AP-1),osteocalcin(OCN/BGP),alkaline phosphatase(ALP),osteopontin(OPN),bone morphogenetic protein(BMP),phosphatidylinositol 3-kinase(PI3K)/C-Jun N-terminal kinase(JNK)/extracellular regulated protein kinase(ErK),osteoprotegerin(OPG),receptor activator of nuclear factor-kB(rANK),monocyte/macrophage colony-stimulating factor(M-CSF),tumor necrosis factor receptor-associated factor 6(TrAF-6),receptor activator of nuclear factor(NF)-KB ligand(rANKL),nuclear factor of activated T cells 1(NFATc1),c-Fos,matrix metallopeptidase-9(MMP-9),glycogen synthase kinase 3β(GSK3B)/B-catenin,nuclear factor E2-related factor 2(Nf2),as well as these related pathways,such as Wnt/p-catenin,BMP-2/SMAd1/5/8,PI3K/AKT,OPG/rANKL/rANK,NF-κB,MAPKs,*** plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its *** reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.

关键词： Osteoporosis Plant-derived polysaccharides Osteogenesis promotion Osteoclasts inhibition

Comparative assessment of the frying efficiency of standard and low linolenic rapeseed oils: Principal Component Analysis (PCA)

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Food and Health 2024年第4期6卷 1-9页

作者： Ming-Ming Hu Chuan-Qi Zhang Xin-Yu Wu national r&d center for Freshwater Fish processing College of Life ScienceJiangxi Normal UniversityNanchang 330022China

In this research,the performance of regular rapeseed oil(rSO)and modified low-linolenic rapeseed oil(LLrO)during frying was assessed using a frying procedure that commonly found in fast-food *** physicochemical attributes of these oils were *** and LLrO differed for initial linolenic acid(12.21%vs.2.59%),linoleic acid(19.15%vs.24.73%).After 6 successive days frying period of French fries,the ratio of linoleic acid to palmitic acid dropped by 54.49%in rSO,higher than that in LLrO(51.54%).The increment in total oxidation value for LLrO(40.46 unit)was observed to be significantly lower than those of rSO(42.58 unit).The changes in carbonyl group value and iodine value throughout the frying trial were also lower in LLrO compared to *** formation rate in total polar compounds for LLrO was 1.08%per frying day,lower than that of rSO(1.31%).In addition,the formation in color component and degradation in tocopherols were proportional to the frying time for two frying ***,a longer induction period was also observed in LLrO(8.87 h)compared to rSO(7.68 h)after frying ***,LLrO exhibited the better frying stability,which was confirmed by principal component analysis(PCA).

关键词： frying rapeseed oil frying oil frying stability principal component analysis

Methylthio side-chain modified quinoidal benzo-[1,2-b:4,5-b'] dithiophene derivatives for high-performance ambipolar organic field-effect transistors

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Science China Chemistry 2024年第10期67卷 3357-3365页

作者： Li Chen Xiaoqi Luo Nuoya Li Shaoqian Peng Qing Jiang di Wu Jianlong Xia State Key Laboratory of Advanced technology for Materials Synthesis and processing Center of Smart Materials and DevicesWuhan University of Technology School of Chemistry Chemical Engineering and Life ScienceWuhan University of Technology department of Chemistry National University of Singapore

Quinoidal small molecule semiconductors hold huge potential in ambipolar organic field-effect transistors（OFETs） and organic spintronic ***,two quinoidal molecules with methylthio side chains were synthesized to develop molecular semiconductors with high ambipolar mobility,designated QBdTS and *** theoretical calculation results reveal that QBdTS has a closed-shell structure while QTBdTS showed an open-shell structure with a biradical character（y0） of 0.46 and its magnetic properties were further investigated using electron paramagnetic resonance（EPr） and superconducting quantum interference device（SQUId） *** methyl side chains showed a large impact on the molecular orbital *** HOMO/LUMO levels of QBdTS and QTBdTS were measured to be -5.66/-4.56 and -5.27/-4.48 eV,respectively,which are favorable for ambipolar charge transport in ***,the spin-coated QBdTS displayed hole and electron mobilities of 0.01 and 0.5 cm2V-1s-1while QTBdTS showed a record high hole mobility of 1.8 cm2V-1s-1and electron mobility of 0.3 ***,comparative studies of the thin film morphologies also manifested the beneficial influence of methyl side chains on film crystallinity and molecule *** results strongly proved that methyl side chain engineering can be a simple but efficient strategy for modulating electronic properties and molecular stacking *** work also represents a big advancement for quinoidal molecular semiconductors in ambipolar OFET applications.

关键词： side-chain modification quinoidal molecules ambipolar diradicals organic field-effect transistors

Photocatalytic applications and modification methods of two-dimensional nanomaterials:a review

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Tungsten 2024年第1期6卷 77-113页

作者： Fan Yang Ping Hu Fan Yang Xing-Jiang Hua Bo Chen Lili Gao Kuai-She Wang School of Metallurgy Engineering Xi’an University of Architecture and TechnologyXi’an 710055China national and Local Joint Engineering research center for Functional Materials processing Xi’an University of Architecture and TechnologyXi’an 710055China

due to its unique electronic structure and special size effect,two-dimensional(2d)nanomaterials have shown great potential far beyond bulk materials in the field of *** to deeply explore the photocatalytic mechanism of 2d nanomaterials and design more efficient 2d semiconductor photocatalysts are research *** review provides a comprehensive introduction to typical 2d nanomaterials and discusses their current application status in the field of *** effects of material properties such as band structure,morphology,crystal face structure,crystal structure and surface defects on the photocatalytic process are *** main modification methods are highlighted,including doping,noble metal deposition,heterojunction,thickness adjustment,defect engineering,and dye sensitization in 2d material ***,the future development of 2d nanomaterials is *** is hoped that this paper can provide systematic and useful information for researchers engaged in the field of photocatalysis.

关键词： Photocatalysis Two-dimensional Nanomaterials Bandgap Modification strategy

Physiological Mechanism of Exogenous Selenium in Alleviating Mercury Stress on Pakchoi(Brassica campestris L.)

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Phyton-International Journal of Experimental Botany 2024年第5期93卷 951-962页

作者： Chengxu Qian Qiangwen Chen Leiyu Jiang Xiaoyan Yang Shen rao Weiwei Zhang Feng Xu College of Horticulture and Gardening Yangtze UniversityJingzhou434025China Enshi Se-run Material Engineering technology Co. Ltd.Enshi445000China Henry Fok School of Biology and Agricultural Shaoguan UniversityShaoguan512005China national r&d for Se-rich Agricultural Products processing technology Wuhan Polytechnic UniversityWuhan430023China

The objective of this study was to explain the physiological mechanisms through which Na_(2)SeO_(3) mitigates the growth and developmental inhibition of pakchoi under HgCl_(2)*** results showed that treatment with HgCl_(2)(40 mg L^(−1))led to reduced biomass,dwarfing,root shortening,and root tip necrosis in *** to control(CK),the activities of superoxide dismutase(SOd)and peroxidase(POd)in Hg treatment increased,and the content of malondialdehyde(MdA)also dramatically increased,which negatively impacted the growth of *** concentrations of Na_(2)SeO_(3)(0.2 mg L^(−1))significantly increased the content of soluble sugars compared with control,while chlorophyll,soluble proteins,free amino acids,and vitamin C had no significant *** results of the mixed treatments with HgCl_(2)and Na_(2)SeO_(3) suggested that selenium may be able to reduce the toxicity of mercury in *** biomass,plant height,root length,chlorophyll content,soluble protein,other physiological indicators,and proline showed significant increases compared with the HgCl_(2)***,the MdA content and mercury accumulation in pakchoi *** results revealed the antagonistic effects of selenium and mercury in ***,a theoretical basis for studying pakchoi’s mercuryexcreted and selenium-rich cultivation technology was provided.

关键词： Selenium mercury stress pakchoi physiological properties antioxidant enzymes

Application and prospects of proteomic technology in inflammation:a review

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Food Science and Human Wellness 2024年第5期13卷 2373-2385页

作者： Senye Wang Yanhai Chu Jiajia Yuan Yiqi Li Zhenhua Liu Xiaoyu Chen Wenyi Kang national r&d center for Edible Fungus processing technology Henan UniversityKaifeng 475004China Functional Food Engineering technology research center Kaifeng 475004China Joint International research Laboratory of Food&Medicine resource Function Kaifeng 475004China College of Agriculture Henan UniversityKaifeng 475004China

Proteomics is a new technology that has been widely applied in the field of life and health *** effectively addresses issues related to the impact of dietary structure on organs,tissues,and cells,as well as the changes in proteins in various organs,tissues,and cells under disease *** differential proteins identified through proteomics can serve as disease biomarkers and target proteins affecting health and can be used for disease diagnosis and health *** this paper,the application of proteomics in the field of infl ammation in recent years was summarized,especially in the therapeutic target and mechanism of action,which opens up a new way for more effective prevention,diagnosis,and treatment of inflammation,and provides medical protection for human life and health.

关键词： Proteomics technology Inflammation Biomarkers Potential target Signaling pathway

Titanium dioxide E171 consumption exacerbates Listeria monocytogenes infection in mice

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Food Quality and Safety 2024年第1期8卷 68-80页

作者：滕跃王瑷琳赵东云李国鹏刘泷泽邹悦夏效东 State Key Laboratory of Marine Food processing and Safety Control National Engineering Research Center of SeafoodSchool of Food Science and TechnologyDalian Polytechnic UniversityDalianChina

The food additive titanium dioxide is commonly utilized to enhance the appearance and flavor of food ***,this substance has been linked to gastrointestinal *** aim of this study was to investigate the impact of dietary exposure of titanium dioxide E171 on Listeria monocytogenes infection in *** were mainly divided into the control,LM group(*** infection),and E171+LM groups(E171 supplementation before *** infection).Pre-exposure to E171 resulted in increased bacterial counts in the liver,spleen,ileum,colon,mesenteric lymph nodes,and feces of mice after *** ***,E171 exposure increased the levels of pro-inflammatory cytokines while attenuating the levels of anti-inflammatory cytokines in mice infected with ***,mice in the E171+LM group exhibited considerably more severe colonic inflammation and worse intestinal barrier function than mice in the LM *** 16S rrNA gene sequencing revealed a shift in the composition of the gut microbiota of mice in the E171+LM group,characterized by a decrease in the relative abundance of Firmicutes and a decrease in the Firmicutes-to-Bacteroidetes *** levels of acetate,butyrate,and isobutyrate were markedly decreased within the cecum of mice in the E171+LM group in comparison to mice in the LM *** conclusion,these results suggest that E171 exposure could exacerbate *** infection in mice,which may provide useful information for future risk assessment of this commonly used food additive.

关键词： E171 L.monocytogenes intestinal barrier function inflammatory responses gut microbiota.