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Clinicopathological features and prognosis assessment of extranodal follicular dendritic cell sarcoma

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World Journal of Gastroenterology 2010年第20期16卷 2504-2519页

作者： Li, Lan Shi, Yong-Hong Guo, Zhi-Juan Qiu, Tian Guo, Lei Yang, Hong-Ying Zhang, Xun Zhao, Xin-Ming Su, Qin Chinese Acad Med Sci Inst Canc Dept Pathol Beijing 100021 Peoples R China Chinese Acad Med Sci Canc Hosp Dept Pathol Beijing 100021 Peoples R China Peking Union Med Coll Beijing 100021 Peoples R China inner Mongolia Med Coll Affiliated Hosp 1 Dept Pathol Hohhot 010059 Inner Mongolia Peoples R China inner Mongolia Med Coll Renmin Hosp Dept Pathol Hohhot 010059 Inner Mongolia Peoples R China Chinese Acad Med Sci Inst Canc Dept Radiol Beijing 100021 Peoples R China Chinese Acad Med Sci Canc Hosp Dept Radiol Beijing 100021 Peoples R China

AIM: To establish a model for prognosis assessment of extranodal follicular dendritic cell (FDC) ***: Nine lesions were examined by routine and molecular *** factors from the new cases and 97 reported cases were analyzed for their prognostic ***: The current lesions were found in f ive male and four female patients,located mainly in the head and neck area and averaging 7.2 cm in *** patients had recurrence or metastasis and three remained free of *** 106 patients (male/female ratio,1.1:1) were aged from 9 to 82 years (median,44 years).The tumor sizes ranged from 1.5 to 21 cm (mean,7.4 cm).Abdominal/pelvic region was affected most frequently (43%).Surgical resection was performed in 100 patients,followed by radiation and/or chemotherapy in 35 of ***-up data were available in 91 cases,covering a period of 3-324 mo (mean,27 mo;median,19 mo).Of the informative cases,38 (42%) had recurrence or metastasis,and 12 (13%) died of the *** tumors were classif ied histologically into lowand high-grade lesions.A size ≥ 5 cm (P = 0.003),highgrade histology (P = 0.046) and a mitotic count ≥ 5/10 HPF (P = 0.013) were associated with tumor *** lesions were def ined as low-,intermediateand high-risk tumors,and their recurrence rates were 16%,46% and 73%,and their mortality rates 0%,4% and 45%,***: Extranodal FDC tumors behave like soft tissue *** clinical outcomes are variable and can be evaluated according to their sizes and grades.

关键词： Extranodal follicular dendritic cell sarcoma Prognosis assessment Histologic grade Immunohistochemistry In situ hybridization Mutation detection

The　Structure　of　Sophoridine　N－oxide　from　inner　mongolian　Sophora　Alopecuroides　L

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Chinese Chemical Letters 1996年第11期7卷 1013-1015页

作者： Zhang, W Mo, RG Xu, HZ inner MONGOLIA UNIV DEPT CHEMHOHHOT 010021PEOPLES R CHINA

Sophoridine N -oxide (A) was isolated from the seeds of inner mongolianSophora alopecuroides L. Its structure was characteraized. Deoxygenation of A gave sophoridine whereas N-oxidation of sophoridine gave two N-oxide... 详细信息

关键词： inner oxide mongolian Sophoridine Structure Alopecuroides

A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy

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Chinese Medical Journal 2012年第3期125卷 428-433页

作者： Hua Wei Wang Dong-mei Cai Lin Sun Chao-feng Fu Guo-sheng Wang Yu-tang Yan Ji Luo Zhi-ling Xu Jing Wang Zhi-yong Xu Geng Shen Fa-rong Xu Wei Wang Jing-feng Ren Xue-jun Jin Wei Zhang, Nan Lau, Elizabeth Oi-Yan Zhang Shu Peking Union Med Coll Dept Cardiol Cardiovasc Inst Beijing 100037 Peoples R China Chinese Acad Med Sci Dept Cardiol Cardiovasc Inst Beijing 100037 Peoples R China Chinese Acad Med Sci Fuwai Hosp Beijing 100037 Peoples R China Shenyang No hosp Dept Cardiol Shenyang 110000 Liaoning Peoples R China Chongqing Med Univ Dept Cardiol Peoples Hosp Chengdu 3 Med Coll Chengdu 2 Chengdu 610031 Sichuan Peoples R China Xi An Jiao Tong Univ Coll Med Dept Cardiol Affiliated Hosp 1 Xian 710061 Shaanxi Peoples R China Zhejiang Univ Sch Med Dept Cardiol Sir Run Run Shaw Hosp Hangzhou 310016 Zhejiang Peoples R China Chinese peoples Liberat Army Gen hosp Dept Cardiol Beijing 100853 Peoples R China Anhui Prov hosp Dept Cardiol Hefei 230001 Anhui Peoples R China Kunming Med Coll Dept Cardiol Affiliated Hosp 1 Kunming 650032 Yunnan Peoples R China Tianjin Chest hosp Dept Cardiol Tianjin 300051 Peoples R China inner mongolian peoples hosp Dept Cardiol Hohhot 010017 Inner Mongolia Mongol Peo Rep Zhejiang Univ Sch Med Dept Cardiol Affiliated Hosp 2 Hangzhou 310009 Zhejiang Peoples R China Zhejiang hosp Dept Cardiol Hangzhou 310030 Zhejiang Peoples R China Nanjing Univ Sch Med Dept Cardiol Affiliated Drum Tower Hosp Nanjing 210008 Jiangsu Peoples R China Sun Yat Sen Univ Dept Cardiol Sun Yat Sun Mem Hosp Guangzhou 510120 Guangdong Peoples R China Capital Med Univ Dept Cardiol Beijing Anzhen Hosp Beijing 100029 Peoples R China Beijing Inst Heart Lung & Blood Vessel Dis Beijing 100029 Peoples R China Shanghai Jiao Tong Univ Sch Med Dept Cardiol Shanghai Peoples Hosp 1 Shanghai 200080 Peoples R China

Background Cardiac resynchronization therapy （CRT） with biventricular pacing improves cardiac function,functional capacity and quality of life in selected patients with heart *** current study aimed to evaluate the efficacy of the intracardiac electrogram （IEGM）-based optimization method,QuickOptTM,in Chinese patients treated with *** Aortic time velocity integrals （AVTI） achieved at the sensed atrioventricular （AV）,paced AV and interventricular （VV） interval settings recommended by both QuickOptTM and standard echocardiographic optimization were measured in 101 *** and the strength of the relationship between the two timing cycle optimization methods were assessed by intra-class correlation coefficient （ICC）.Results The ICC showed good agreement and correlation with what the AVTI achieved at the optimal sensed AV （ICC=0.9683 （0.9535-0.9785））,paced AV （ICC=0.9642 （0.9475-0.9757）） and VV （ICC=0.9730 （0.9602-0.9817）） interval settings determined by the two optimization *** average time required by echocardiographic optimization and by QuickOptTM were （78.32±32.40） minutes and （1.98±1.64） minutes respectively （P 〈0.0001）.Conclusion The QuickOptTM algorithm provides a quicker,simpler and reliable alternative to the standard method for timing cycle optimization.（*** Reference Number：NCT00918294）

关键词： heart failure cardiac resynchronization therapy atrioventricular interval interventricular interval timing cycle optimization echocardiography aortic velocity time integral intracardiac electrogram QuickOptTM

Effects of Mg on Mechanical Properties of 35CrNi3MoV Steel

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Journal of Materials Science & Technology 1998年第2期14卷 104-108页

作者： Yu, Yueguang Fu, Jie Wang, Anren Chen, Boping Sun, Wenshan Univ Sci & Technol Beijing Beijing 100083 Peoples R China inner Mongolia Metall Mat Res Inst Baotou 014034 Peoples R China

The results show that Mg has less effect on the tensile properties and hardness of the steel at room temperature, but a right amount of Mg improves impact and fracture toughness and decreases the fracture-transition temperature considerably due to inclusions modification, as well as prolongs the notch stress rupture life dramatically through strengthening grain boundary and modifying boundary carbides. There is an optimum Mg content, which is about 0.0030% in the experimental 35CrNi3MoV steel. (Edited author abstract) 8 Refs.

关键词： Steel

Inclusion Modification with Mg Treatment for 35CrNi3MoV Steel

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Journal of Materials Science & Technology 1998年第1期14卷 53-56页

作者： Fu, J Yu, YG Wang, AR Chen, BP Sun, WS Univ Sci & Technol Beijing Beijing 100083 Peoples R China inner Mongolia Met Mat Res Inst Baotou 014034 Peoples R China

The effects of Mg on the inclusion characteristics of 35CrNi3MoV steel have been studied. The results show that Mg treatment reduces obviously the amount of inclusion in the steel. Magnesium and oxygen in liquid steel form dispersed fine particles of MgO, to which other oxides or sulphides nucleated at heterogeneity and grown during solidification. In this way the inclusions are modified. The small spherical inclusions containing MgO have been observed in the Mg treated steel in contrast to the large angular inclusions with Al2O3 in the conventional steel. Especially the elongated MnS inclusion is replaced by small MgS . MgO or MgS. MnS . MgO complex inclusion. The formation of inclusions have been discussed.

关键词： Steel metallurgy

Comparative Analysis on Microstructure and Mechanical Properties between EBW and TANDEM Welding of 7A52 Aluminum Alloy Joint

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稀有金属材料与工程 2011年第S4期40卷 68-73页

作者： Zhai Xiwei1,2,Chen Furong1,2,Bi Liangyan1,2,Zhang Chuanchen3 1College of Materials Science and Engineering,inner Mongolia University of Technology,Hohhot 010051,China2Key Laboratory of Materials Processing & Control Engineering of inner Mongolia Autonomous Region,Hohhot 010051,China3School of Materials Science and Engineering,University of Science and Technology Beijing,Beijing 100083,China inner Mongolia Univ Technol Coll Mat Sci & Engn Hohhot 010051 Peoples R China Key Lab Mat Proc & Control Engn inner Mongolia Au Hohhot 010051 Peoples R China Univ Sci & Technol Beijing Sch Mat Sci & Engn Beijing 100083 Peoples R China

The plates with 20mm thickness of 7A52 aluminum alloy were welded by electron beam welding and TANDEM welding with ER5356 filler,*** microstructure and mechanical properties of the joints were *** results showed that the microstructure of EBW metal was finer and tighter than TANDEM *** heat-affected zone of the EBW joint was narrower,its hardness was higher and the tensile strength improved obviously compared to TANDEM *** quality control of the EBW joint was made without abnormal porosity,inclusions and ***,the EBW joint of 7A52 aluminum alloy showed excellent performance.

关键词： 7A52 aluminum alloy electron beam welding TANDEM welding microstructure mechanical properties

Identification of potential diagnostic and prognostic biomarkers for breast cancer based on gene expression omnibus

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世界临床病例杂志 2023年第27期11卷 6344-6362页

作者： Xiong Zhang Zhi-Hui Mi Department of Pathology HuLunBuir Peoples’s HospitalHuLunBuir 010018Nei Monggol Autonomous RegionChina Department of Research and Marketing Inner Mongolia Di An Feng Xin Medical Technology Co.LTDHuhhot 010010Nei Monggol Autonomous RegionChina

BACKGROUND Breast cancer is regarded as a highly malignant neoplasm in the female population,posing a significant risk to women’s overall *** prevalence of breast cancer has been observed to rise in China,accompanied by an earlier age of onset when compared to Western *** cancer continues to be a prominent contributor to cancer-related mortality and morbidity among women,primarily due to its limited responsiveness to conventional treatment *** diagnostic process is challenging due to the presence of non-specific clinical manifestations and the suboptimal precision of conventional diagnostic *** is a prevailing uncertainty regarding the most effective screening method and target populations,as well as the specificities and execution of screening *** To identify diagnostic and prognostic biomarkers for breast *** Overlapping differentially expressed genes were screened based on Gene Expression Omnibus(GSE36765,GSE10810,and GSE20086)and The Cancer Genome Atlas datasets.A protein-protein interaction network was applied to excavate the hub genes among these differentially expressed *** Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses,as well as gene set enrichment analyses,were conducted to examine the functions of these genes and their potential mechanisms in the development of breast *** clarification of the diagnostic and prognostic roles of these genes,Kaplan–Mei-er and Cox proportional hazards analyses were *** This study demonstrated that calreticulin,heat shock protein family B member 1,insulin-like growth Factor 1,interleukin-1 receptor 1,Krüppel-like factor 4,suppressor of cytokine signaling 3,and triosephosphate isomerase 1 are potential diagnostic biomarkers of breast cancer as well as potential treatment targets with clinical *** The screening of biomarkers is of guiding significance for the diagnosis and prognosis of the disease

关键词： Breast cancer Diagnostic biomarker The Cancer Genome Atlas datasets Gene expression omnibus Enrichment analysis

Lack of association between three single nucleotide polymorphisms in the PARK9, PARK15, and BST1 genes and Parkinson＇s disease in the northern Han Chinese population

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Chinese Medical Journal 2012年第4期125卷 588-592页

作者： Zhu Lan-hui Luo Xiao-guang Zhou Yi-shu Li Feng-rui Yang Yi-chun Ren Yan Pang Hao China Med Univ Sch Forens Med Shenyang 110001 Liaoning Peoples R China China Med Univ Hosp 1 Dept Neurol Shenyang 110001 Liaoning Peoples R China Baotou Med Coll Dept Forens Med Baotou 014060 Inner Mongolia Peoples R China Dalian Univ Affiliated Xinhua Hosp Dept Neurosurg Dalian 116021 Liaoning Peoples R China

Background Parkinson＇s disease （PD） is an autosomally inherited neurodegenerative disease in elderly *** etiology of PD has long been thought to be associated with both genetic and environmental *** explore potential genetic risk factors for PD in the northern Han Chinese population,we investigated three single nucleotide polymorphisms （SNPs）（rs4538475,rs11107 and rs12564040） in the BST1,PARK15 and PARK9 *** Genomic DNA from 215 PD patients and 212 matched controls was amplified in two independent PCR systems and subsequently genotyped by digestion with the endonuclease *** parameter and association studies were carried out with SPSS 13.0 and PLINK 1.07 *** We could accurately detect all genotypes in the three loci with the PCR-RFLP or mismatched PCR-RFLP *** observed heterozygosities of the rs4538475 and rs11107 loci in PD and control groups ranged from 0.460-0.481 and 0.410-0.441,in BST1,PARK15 respectively,while we detected no heterozygosity at the rs12564040 locus in *** similar distributions of genotypic frequency between both groups suggest that the three SNPs investigated in this study are unlikely to play roles as common risk factors or pathogenic mutations for PD in northern Han *** The SNPs investigated in the BST1,PARK15 and PARK9 genes associated with PD susceptibility are not associated with PD in the northern Han Chinese population.

关键词： Parkinson disease PARK9 PARK15 BST1 genetic association studies

Preparation　of　Homocitrate　using　a　Modified　Method

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Chemical Research in Chinese Universities 1998年第1期14卷 93-95页

作者： Li, Zeng-chun Xu, Ji-qing inner Mongolia Natl Teachers Coll Dept Chem Tongliao 028043 Peoples R China Jilin Univ Dept Chem Changchun 130023 Peoples R China

ＰｒｅｐａｒａｔｉｏｎｏｆＨｏｍｏｃｉｔｒａｔｅｕｓｉｎｇａＭｏｄｉｆｉｅｄＭｅｔｈｏｄＬＩＺｅｎｇ－ｃｈｕｎ（ＤｅｐａｒｔｍｅｎｔｏｆＣｈｅｍｉｓｔｒｙ，ＩｎｎｅｒＭｏｎｇｏｌｉａＮａｔｉｏｎａｌＴｅａｃｈｅｒｓＣ... 详细信息

ＰｒｅｐａｒａｔｉｏｎｏｆＨｏｍｏｃｉｔｒａｔｅｕｓｉｎｇａＭｏｄｉｆｉｅｄＭｅｔｈｏｄＬＩＺｅｎｇ－ｃｈｕｎ（ＤｅｐａｒｔｍｅｎｔｏｆＣｈｅｍｉｓｔｒｙ，ＩｎｎｅｒＭｏｎｇｏｌｉａＮａｔｉｏｎａｌＴｅａｃｈｅｒｓＣｏｌｌｅｇｅ，Ｔｏｎｇｌｉａｏ，０...

关键词： Preparation using Modified Homocitrate Method