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Animal exercise studies in cardiovascular research:Current knowledge and optimal design--A position paper of the Committee on Cardiac Rehabilitation,Chinese Medical Doctors’Association

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Journal of sport and Health science 2021年第6期10卷 660-674,F0003页

作者： Yihua Bei Lei Wang Rongjing Ding Lin Che Zhiqing Fan Wei Gao Qi Liang Shenghui Lin Suixin Liu Xiao Lu Yuqin Shen Guifu Wu Jian Yang Guolin Zhang Wei Zhao Lan Guo Junjie Xiao Institute of Geriatrics Affiliated Nantong Hospital of Shanghai UniversitySixth People’s Hospital of NantongSchool of MedicineShanghai UniversityNantong 226011China Cardiac Regeneration and Ageing Lab Institute of Cardiovascular SciencesShanghai Engineering Research Center of Organ RepairSchool of Life ScienceShanghai UniversityShanghai 200444China Department of Rehabilitation Medicine Nanjing University of Chinese MedicineNanjing 210023China Department of Cardiology Peking University People’s HospitalBeijing 100044China Department of Cardiology Tongji Hospital Affiliated to Tongji UniversityTongji University School of MedicineShanghai 200065China Department of Cardiology Daqing Oilfield General HospitalDaqing 163000China Department of Cardiology and Institute of Vascular Medicine Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesKey Laboratory of Molecular Cardiovascular ScienceMinistry of EducationBeijing Key Laboratory of Cardiovascular Receptors ResearchBeijing 100191China Department of Rehabilitation Medicine First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China School of Medicine Huaqiao UniversityQuanzhou 362021China division of Cardiac Rehabilitation Department of Physical Medicine and RehabilitationXiangya Hospital of Central South UniversityChangsha 410008China Department of Rehabilitation Medicine First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Cardiology Eighth Affiliated Hospital of Sun Yat-Sen UniversityShenzhen 518033China Guangdong Innovative Engineering and Technology Research Center for Assisted Circulation Sun Yat-Sen UniversityShenzhen 518033China NHC Key Laboratory of Assisted Circulation Sun Yat-Sen UniversityGuangzhou 510080China Department of Rehabilitation Medicine Shanghai Xuhui Central HospitalShanghai 200031China Cardiac Rehabilitation Department Guangdong Cardiovascular InstituteGuangdong Provincial People’s HospitalGuangdo

Growing evidence has demonstrated exercise as an effective way to promote cardiovascular health and protect against cardiovascular diseases However,the underlying mechanisms of the beneficial effects of exercise have yet to be *** exercise studies are widely used to investigate the key mechanisms of exercise-induced cardiovascular ***,standardized procedures and well-established evaluation indicators for animal exercise models are needed to guide researchers in carrying out effective,high-quality animal studies using exercise to prevent and treat cardiovascular *** our review,we present the commonly used animal exercise models in cardiovascular research and propose a set of standard procedures for exercise training,emphasizing the appropriate measurements and analysis in these chronic exercise *** also provide recommendations for optimal design of animal exercise studies in cardiovascular research,including the choice of exercise models,control of exercise protocols,exercise at different stages of disease,and other considerations,such as age,sex,and genetic *** hope that this position paper will promote basic research on exercise-induced cardiovascular protection and pave the way for successful translation of exercise studies from bench to bedside in the prevention and treatment of cardiovascular diseases.

关键词： Animal studies Cardiovascular disease Cardiovascular research Exercise Exercise models

Habitual physical activity levels and sedentary time of children in different childcare arrangements from a nationally representative sample of Canadian preschoolers

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Journal of sport and Health science 2020年第6期9卷 657-663页

作者： Julie Statler Piotr Wilk Brian W.Timmons Rachel Colley Patricia Tucker Faculty of Health sciences University of Western OntarioLondonOntarioN6A 3K7Canada Schulich School of Medicine&Dentistry University of Western OntarioLondonOntarioN6A 3K7Canada Department of Pediatrics McMaster UniversityHamiltonOntarioL8S 4L8Canada division of Health Analysis Statistics CanadaOttawaOntarioK1A 0T6Canada School of Occupational Therapy University of Western OntarioLondonOntarioN6A 3K7Canada

Background:Children spend substantial time in childcare,and the reasons parents choose a particular childcare type may differ by ***,little is known about how childcare type influences habitual(full day)activity levels among ***,exploring patterns between childcare type and habitual physical activity(PA)(i.e.,light,moderate-to-vigorous PA(MVPA),and total PA)and sedentary time(ST)in young Canadian children is ***:A nationally representative sample of preschoolers from Cycles 3 and 4 of the Canadian Health Measures Survey was used in this cross-sectional *** type(e.g.,center-based childcare,home-based childcare,home with parent,kindergarten)was reported by *** wore an Actical accelerometer for 7 *** and population-spcific cut-points were applied to delineate PA intensities and *** means and sample totals were calculated to examine average daily and hourly rates of ***:Preschoolers’rates of MVPA and total PA from the 4 childcare arrangements ranged from 65.99 min/day to 74.62 min/day(5.48-6.18 min/h)and 274.20 min/day to 281.66 min/day (22.69-23.21 min/h),respectively,while ST ranged from 443.13 min/day to 460.57 min/day(36.80-37.31 min/h).No significant differences were observed in daily or hourly rates of ***:This study provides a snapshot of the levels of PA and ST among preschoolers in various childcare settings at a national level,with no differences observed in habitual activity levels based on childcare *** research is needed to clarify the relationship between young children’s PA and childcare type,with consideration given to the quality of the childcare settings.

关键词： Early learning environment Motor activity Preschool Screen time

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基因位点和慢性、广泛性的肌肉骨骼疼痛

中国康复 2021年第10期36卷 611-611页

作者：赵婧(译) Rahman S Department of Twin Research and Genetic Epidemiology School of Life Course Sciences King's College London Department of Research Innovation and EducationDivision of Clinical Neuroscience Oslo University Hospital Department of Neurology Oslo universitetssykehus Ullevål Department of Internal Medicine Erasmus Medical Center K. G. Jebsen Center for Genetic Epidemiology Department of Public Health and Nursing Faculty of Medicine and Health Sciences Norwegian University of science and Technology Research and Communication Unit for Musculoskeletal Health (FORMI) Department of Research Innovation and Education Division of Clinical Neuroscience Laboratory of Theoretical and Applied Functional Genomics Novosibirsk State University PolyOmica ‘s-Hertogenbosch Laboratory of Recombination and Segregation Analysis Institute of Cytology and Genetics 10 Lavrentiev Avenue Department of Neuromedicine and Movement science Faculty of Medicine and Health Sciences Clinical Research Unit Central Norway St Olavs University Hospital Department of Public Health and Nursing Faculty of Medicine and Health Sciences HUNT Research Center Department of Public Health and Nursing Faculty of Medicine and Health Sciences

慢性广泛性疼痛(CWP)的全球患病率大约为10.6%。虽然已知慢性疼痛有共同的遗传因素,但有关特定基因位点影响的数据仍然没有定论。这项对CWP患者的研究调查了这种情况的病理生理机制。使用英国数据库进行了一项全基因组的CWP患者关联研究... 详细信息

慢性广泛性疼痛(CWP)的全球患病率大约为10.6%。虽然已知慢性疼痛有共同的遗传因素,但有关特定基因位点影响的数据仍然没有定论。这项对CWP患者的研究调查了这种情况的病理生理机制。使用英国数据库进行了一项全基因组的CWP患者关联研究,包括249843名参与者。CWP表型是通过结合全身疼痛至少持续3个月的自我报告诊断来定义的。

关键词：病理生理机制自我报告基因位点慢性疼痛遗传因素肌肉骨骼疼痛患病率数据库

Harrogate consensus agreement:Cycling-specific sport-related concussion

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sports Medicine and Health science 2021年第2期3卷 110-114页

作者： Jeroen Swart Xavier Bigard Thomas Fladischer Roger Palfreeman Helge Riepenhof Nigel Jones Neil Heron division of Exercise&sports Medicine University of Cape TownFIMS Scientific CommissionUAE Tem EmiratesWorld Tour Professional Cycling TeamUnited Arab Emirates Medical Director International Cycling UnionAigleSwitzerland LKH Hochsteiermark Orthopedics&Traumatology Bruck/MurAustria Team Mitchelton Scott Australia Department of sports and Rehabilitation Medicine BG Trauma Hospital of HamburgGermany Head of Medical British CyclingUK School of Medicine Dentistry and Biomedical sciences Queen's UniversityBelfast.Team IneosWorld Tour Professional Cycling TeamUK

sport-related concussion(SRC)is a common and increasingly recognised sport-related injury and accounts for between 1%and 9%of all cycling-specific *** has been drawn to the difficulty in managing suspected SRC in a fast-paced sport such as road cycling,particularly the lack of an effective and time-efficient assessment protocol.A meeting on cycling SRC was convened in Harrogate,United Kingdom,in an attempt to resolve this *** aim was to agree on standard terminology,definitions,diagnostic protocols and return to play protocols for the various differing codes of cycle *** experts in the field of cycling medicine were invited to participate by the International Cycling Union and are the authors of this *** panel recognised that the sport of cycling consists of varied disciplines,some of which provide a setting in which a sideline assessment is possible which is in line with the Berlin Consensus ***,other disciplines provide challenging circumstances where health care providers have limited access to participants and where participants are unable to discontinue participation and participate in sideline ***-based discipline-specific protocols and guidelines which recognise the limitations posed by these circumstances,but nevertheless,improve on the current situation specific to the sport of cycling are presented as a potential solution to the unique chal-lenges posed by these cycling disciplines.

关键词： sport-related concussion Cycling

Characteristics of Steps and Analysis of the Technical Procedure of the Block in Middle Men’s Volleyball Players

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Journal of sports science 2019年第4期7卷 123-133页

作者： Rui Pinto Susana Vale Paulo Vicente Joao Centre for Research and Innovation in Education(inED)of Escola Superior de Educacao of Politécnico do Porto Porto 4000Portugal Research Center for sport sciences Health and Human Development(CIDESD)University of Trás-os-Montes e Alto DouroVila Real 5000Portugal

In modern volleyball,the middle blocker is regarded as one of the most important players for the tactical organization,because he is frequently requested for both defensive and offensive *** the block action,the coach must always consider the characteristics of the middle blocker,and his intervention should contemplate the ball tempo and the zone where the opposing attack *** purpose of this study is to understand what the movements are that precede the action of the technical gesture of the *** sample consisted of n=4,895 actions representing 30 footages of games from the 1st male volleyball division in the Portuguese league from season 2013/*** have analyzed the movements that each middle blocker has performed during the pre-block *** have also recorded the ball tempo on the opposing setter and the zone where the opposing attack *** have established that there is a relationship between the movements performed and the attack zones(p≤0.001),as well as between the movements and the type of setting,in each attack zone(p≤0.001 in all of them).This way,we have determined that the Crossover Step is the most frequent movement,followed by the Drive Step.

关键词： Volleyball movements middle blocker block

小P值并不能保证可靠结果:以帕金森病的静息态脑功能成像元分析为例

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science Bulletin 2021年第21期66卷 2148-2152,M0003页

作者：贾熙泽赵娜董昊铭孙家伟 Marek Barton Roxana Burciu Nicolas Carrière Antonio Cerasa 陈博宇陈俊 Stephen Coombes Luc Defebvre Christine Delmaire Kathy Dujardin Fabrizio Esposito 范国光 Federica Di Nardo 冯怡萱 Brett W.Fling Saurabh Garg Moran Gilat Martin Gorges Shu-Leong Ho Fay B.Horak 胡晓胡晓飞黄飚黄沛钰贾泽娟 Christina Jones Jan Kassubek Lenka Krajcovicova Ajay Kurani 李静李晴刘爱萍刘波刘虎刘卫国 Renaud Lopes 娄毓婷罗巍 Tara Madhyastha 毛妮妮 Grainne McAlonan Martin J.McKeown Shirley Pang Andrea Quattrone Irena Rektorova Alessia Sarica 商慧芳 James M.Shine Priyank Shukla Tomas Slavicek 宋潇鹏 Gioacchino Tedeschi Alessandro Tessitore David Vaillancourt 王健王珏 Z.Jane Wang 魏鲁庆邬霞徐晓俊闫磊杨靓杨万群姚乃琳张得龙张久权张敏鸣张艳玲周彩红严超赣左西年 Mark Hallett 吴涛臧玉峰 Center for Cognition and Brain Disorders the Affiliated HospitalHangzhou Normal UniversityHangzhou 310015China Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou 311121China National Basic science Data Center Beijing 100190China State Key Laboratory of Cognitive Neuroscience and Learning&McGovern Institute for Brain Research Beijing Normal UniversityBeijing 100875China School of Information and Electronics Technology Jiamusi UniversityJiamusi 154007China Neuroscience Program Central European Institute of TechnologyCEITECMasaryk UniversityBrno 62500Czech Republic Department of Applied Physiology and Kinesiology University of FloridaGainesville FL 32611USA Univ.Lille InsermCHU LilleU1172-LilNCog-Lille Neuroscience&CognitionLille F-59000France The Institute for Biomedical Research and Innovation National Research CouncilMangone CS 87050Italy Department of Radiology The First Affiliated Hospital of China Medical UniversityShenyang 110001China Department of Radiology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China Department of Medicine Surgery and DentistryScuola Medica SalernitanaUniversity of SalernoFiscianoSA 132-84084Italy Department of Advanced Medical and Surgery sciences University of Campania“Luigi Vanvitelli”Caserta 81100Italy Eye Center of the 2nd Affiliated Hospital Medical College of Zhejiang UniversityHangzhou 310020China Zhejiang Provincial Key Lab of Ophthalmology Hangzhou 310020China Department of Health and Exercise science Colorado State UniversityFort Collins CO 80523USA Pacific Parkinson’s Research Centre University of British ColumbiaVancouver BC V6E 2M6Canada Department of Medicine(Neurology)University of British Columbia Vancouver BC V6T 1B7Canada Brain and Mind Center The University of SydneySydney NSW 2006Australia Department of Neurology Ulm UniversityUlm 89081Germany division of Neurology Department of MedicineQueen Mary HospitalUniversity of Hong KongHong Kong 999077China Department of

Thousands of resting state functional magnetic resonance imaging(RS-f MRI)articles have been published on brain *** precise localization of abnormal brain activity,a voxel-level comparison is *** of the large number of voxels in the brain,multiple comparison correction(MCC)must be performed to reduce false positive rates,and a smaller P value(usually including either liberal or stringent MCC)is widely recommended[1].

关键词：帕金森病 precise correction

Influence of structural defects on charge density waves in 1T-TaS_(2)

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Nano Research 2023年第8期16卷 11528-11539页

作者： Iaroslav Lutsyk Karol Szalowski Pawel Krukowski Pawel Dabrowski Maciej Rogala Witold Kozlowski Maxime Le Ster Michal Piskorski Dorota A.Kowalczyk Wojciech Rys Rafal Dunal Aleksandra Nadolska Klaudia Toczek Przemyslaw Przybysz Ewa Lacinska Johannes Binder Andrzej Wysmolek Natalia Olszowska Jacek J.Kolodziej Martin Gmitra Takuma Hattori Yuji Kuwahara Guang Bian Tai-Chang Chiang Pawel J.Kowalczyk Faculty of Physics and Applied Informatics University of LodzPomorska 149/15390-236 LodzPoland Faculty of Physics University of WarsawPasteura 502-093 WarsawPoland Faculty of Physics Astronomyand Applied Computer ScienceJagiellonian UniversityLojasiewicza 1130-348 KrakowPoland National Synchrotron Radiation Centre SOLARIS Jagiellonian UniversityCzerwone Maki 9830-392 KrakówPoland Institute of Physics Faculty of SciencePavol JozefŠafárik University in KošicePark Angelinum 904001 KošiceSlovakia Institute of Experimental Physics Slovak Academy of SciencesWatsonova 4704001 KošiceSlovakia Department of Precision Engineering Graduate School of EngineeringOsaka University2-1 Yamada-okaSuita 565-0871Japan Department of Physics and Astronomy University of MissouriColumbiaMissouri 65211USA Department of Physics and Frederick Seitz Materials Research Laboratory University of Illinois at Urbana-ChampaignUrbanaIllinois 61801-3080USA

The influence of intrinsic defects of 1T-TaS_(2)on charge density waves(CDWs)is studied using scanning tunneling microscopy and spectroscopy(STM,STS),angle-resolved photoelectron spectroscopy(ARPES),and density functional theory(DFT).We identify several types of structural defects and find that most have a local character limited to a single CDW site,with a single exception which effectively behaves as a dopant,leading to band-bending and affecting multiple neighboring *** only one type of defect can be observed by STM topographic imaging,all defects are easily resolved in STS *** results indicate modulation of the Mott band gap commensurate with the CDW and breaking of the three-fold symmetry of electronic *** calculations(with included Coulomb interactions)are used to investigate the electronic structure,focusing on both sulfur vacancy and oxygen-sulfur *** sulfur vacancy system,characterized with a metallic behavior,is identified as the origin of one of the experimentally observed ***,the effect of oxidation of 1T-TaS_(2)depends on the substitution site,leading to the heterogeneity of electronic properties.

关键词： structural charge sulfur

膳食碳水化合物:其质量与摄入量对慢性疾病的作用

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英国医学杂志中文版 2021年第3期24卷 139-143页

作者： David S Ludwig Frank B Hu Luc Tappy Jennie Brand-Miller 潘天园(译) 任菁菁(校) New Balance Foundation Obesity Prevention Center Boston Children′s HospitalBostonMAUSA Department of Pediatrics Harvard Medical SchoolBostonMAUSA Department of Nutrition Harvard T H Chan School of Public HealthBostonUSA Channing division of Network Medicine Brigham and Women′s HospitalHarvard Medical SchoolBoston Department of Physiology University of LausanneLausanneSwitzerland Charles Perkins Centre School of Life and Environmental SciencesUniversity of SydneySydneyAustralia 浙江大学医学院附属第一医院

David S Ludwig及其同事调查了不同类型的碳水化合物和健康之间的联系。碳水化合物是唯一一类无最低摄入要求,但含有大量主要营养素的物质。虽然很多人以碳水化合物为他们生存的主要能源来源,但也有人常年食用几乎不含碳水化合物的食物... 详细信息

David S Ludwig及其同事调查了不同类型的碳水化合物和健康之间的联系。碳水化合物是唯一一类无最低摄入要求,但含有大量主要营养素的物质。虽然很多人以碳水化合物为他们生存的主要能源来源,但也有人常年食用几乎不含碳水化合物的食物(因纽特人、拉普兰人,和一些印第安人)1-2。

关键词：碳水化合物因纽特人主要营养素慢性疾病拉普兰摄入量印第安人能源来源