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A preliminary snapshot of the trophic model and ecosystem attributes of Kaptai reservoir ecosystem, Bangladesh

Journal of Oceanology and Limnology 2021年第1期39卷 223-241页

作者： Mst Halima KHATUN Partho Protim BARMAN YI Jundong Saymuna Tarin LUPA Md Mahiuddin ZAHANGIR Qun LIU College of fisheries Ocean University of ChinaQingdao 266003China department of fisheries Management Bangladesh Agricultural UniversityMymensingh 2202Bangladesh department of fish Biology and biotechnology Chattogram Veterinary and Animal Sciences UniversityChattogram-4225Bangladesh

A mass-balanced Ecopath model presents a quantitative description of the trophic structure,fl ow of energy and trophic interaction among ecological groups of an *** Ecopath with Ecosim(EwE)modeling program(Version 6.5)was used to develop a preliminary trophic model for a tropical freshwater *** total fi sh biomass was 6.245 t/km 2 and the highest trophic level of the reservoir was 3.362(for snakehead).The ecosystem is phytoplankton based because primary producers originated 68%and detritus originated 32%of the total fl ow from lower trophic *** gross effi ciency of the fi shery was 0.004,suggesting the ineffi ciency of the *** positive eff ect of phytoplankton and detritus on most of the other groups were evident from mixed trophic analysis while moderately higher ecotrophic effi ciency(EE)of phytoplankton shows the ecosystem’s potential bottom-up *** competition for the same resources among diff erent groups was also *** ratio of primary production/respiration(1.969)suggests that the ecosystem is at the developing stage and utmost contemplation should be given to concerned human *** low value of relative ascendancy(30.13)and overhead(69.87)reveals the stability of the ecosystem and some degrees of *** also predicts the presence of signifi cant strength in reserve of the system to withstand or overcome any ***,ecologically sustainable resource management plans should be implemented to ensure the sustainability of this reservoir resources.

关键词： Ecopath Kaptai reservoir trophic interaction transfer effi ciency energy flow

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Neuroprotective effects of erythropoietin on neurodegenerative and ischemic brain diseases: the role of erythropoietin receptor

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Neural Regeneration Research 2017年第9期12卷 1381-1389页

作者： Carolina Castillo Hernández Carlos Felipe Burgos Angela Hidalgo Gajardo Tiare Silva-Grecchi Javiera Gavilan Jorge Roberto Toledo Jorge Fuentealba Laboratory of Screening of Neuroactive Compounds Department of Physiology School of Biological Sciences University of Concepción Laboratory of biotechnology and Biopharmaceutical Department of Pathophysiology School of Biological Sciences University of Concepción

Erythropoietin （Epo） is a fundamental hormone in the regulation of hematopoiesis, and other secondary roles mediated by the binding of the hormone to its specific receptor （EpoR）, which leads to an activation of key signaling pathways that induce an increase in cell differentiation, apoptosis control and neuroprotection. It has been suggested that their ftmction depends on final conformation of glycosylations, related with affinity to the receptor and its half-life. The presence of EpoR has been reported in different tissues including central nervous system, where it has been demonstrated to exert a neuroprotective function against oxidative stress conditions, such as ischemic injury and neurodegenerative diseases. There is also evidence of an increase in EpoR expression in brain cell lysates of Alzheimer＇s patients with respect to healthy patients. These results are related with extensive in vitro experimental data of neuroprotection obtained from cell lines, primary cell cultures and hippocampal slices. Additionally, this data is correlated with in vivo experiments （water maze test） in mouse models of Alzheimer＇s disease where Epo treatment improved cognitive function. These stud- ies support the idea that receptor activation induces a neuroprotective effect in neurodegenerative disorders including dementias, and especially Alzheimer＇s disease. Taken together, available evidence suggests that Epo appears to be a central element for EpoR activation and neuroprotective properties in the central nervous system. In this review, we will describe the mechanisms associated with neuroprotection and its relation with the activation of EpoR in order with identify new targets to develop pharmacological strategies.

关键词： erythropoietin erythropoietin receptor neuroprotection anti-apoptosis Alzheimer's disease

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Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice

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World Journal of Gastroenterology 2006年第41期12卷 6646-6651页

作者： Sergey V Popov Pavel A Markov Ida R Nikitina Sergey Petrishev Vasily Smirnov Yury S Ovodov department of Molecular Immunology and biotechnology Institute of PhysiologyKomi Science CentreThe Urals Branch of the Russian Academy of Sciences50 Pervomaiskaya str.Syktyvkar 167982Russia

AIM： To study isolation and chemical characterization of pectin derived from the common cranberry Vaccin/um oxycoccos L. （oxycoccusan OP） and the testing of its preventive effect on experimental colitis. METHODS： Mice were administrated orally with OP two days prior to a rectal injection of 5% acetic acid and examined for colonic damage 24 h later. Colonic inflammation was characterized by macroscopical injury and enhanced levels of myeloperoxidase activity measured spectrophotometrically with o-phenylene diamine as the substrate. The mucus contents of the colon were determined by the Alcian blue dye binding method. Vascular permeability was estimated using 4% Evans blue passage after i.p. injection of 0.05 mol/L acetic acid. RESULTS： In the mice treated with OP, colonic macroscopic scores （1.1 ± 0.4 vs 2.7, P 〈 0.01） and the total square area of damage （10 ± 2 vs 21 ± 7, P 〈 0.01） were significantly reduced when compared with the vehicle-treated colitis group. OP was shown to decrease the tissue myeloperoxidase activity in colons （42 ± 11 vs 112 ± 40, P 〈 0.01） and enhance the amount of mucus of colitis mice （0.9 ± 0.1 vs 0.4 ± 0.1, P 〈 0.01）. The level of colonic malondialdehyde was noted to decrease in OP-pretreated mice （3.6 ± 0.7 vs 5.1 ± 0.8, P 〈 0.01）. OP was found to decrease the inflammatory status of mice as was determined by reduction of vascular permeability （161 ± 34 vs 241 ± 21, P 〈 0.01）. Adhesion of peritoneal neutrophils and macrophages was also shown to decrease after administration of OP （141 ± 50 vs 235 ± 37, P 〈 0.05）. CONCLUSION： Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected. A reduction of neutrophil infiltration and antioxidant action may be implicated in the protective effect of oxycoccusan.

关键词： Common cranberry Vaccinium oxycoccos L Pectin Colitis Anti-inflammatory Mice

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Anti-obesity Effects of Ginsenosides in High-Fat Diet-Fed Rats

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Chinese Journal of Integrative Medicine 2019年第12期25卷 895-901页

作者： Hyun-Jung Park Ji Hyun Kim Insop Shim department of physiology College of MedicineKyung Hee UniversitySeoul(130-701)Republic of Korea department of Food Science&biotechnology College of Science and EngineeringSuwon-si(16227)Republic of Korea

Objective: To examine the anti-obesity effects of ginsenosides in Korea Red Ginseng(KRG, Panax ginseng) in rats fed with a high-fat diet(HFD). Methods: Twenty-five 4-week-old obesity rats after receiving an HFD for 5 weeks;subsequently, they were additionally treated with ginsenosides Rb1, Rd, Rg1, or Re(10 mg/kg, intraperitoneal injection) for a further 3 weeks(n=5 in each group). The control rats were fed a normal diet. The food consumption, body weight, locomotor activity, serum lipids, adipose tissues, nitric oxide(NO) expression, leptin, neuropeptide Y(NPY), cholecystokinin(CCK) in the brains were measured. Results: In the HFD-fed rats, body weight, body fat mass, serum levels of leptin and NO were significantly higher than in the control rats(P<0.05 or P<0.01). However, the treatment of Rd, Re, and Rb1 markedly decreased body fat mass and body weight(P<0.05). The serum level of leptin and NO in ginsenoside-treated rats were markedly lower than the control group(P<0.01). The expression of NPY and CCK in the hypothalamic nuclei showed insignificant difference among groups. However, the expression of NPY immunoreactive neurons in the hypothalamus was significantly reduced in the Rb1-treated group(P<0.05). Conclusion: PD-type ginsenoside Rb1 from the crude saponins of KRG may be a useful compound for the treatment of obesity and related disorders through the modulation of peripheral and central appetite-regulating signals.

关键词： Panax ginseng ginsenosides hypothalamus obesity

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Second to Fourth Digit Ratio(2D:4D) as a Predictor of Adult Circulating Sex Hormones and Overweight/Obesity in Ado-Ekiti Nigeria

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Biomedical and Environmental Sciences 2018年第7期31卷 539-544页

作者： OYEYEMI Fatai Bolaji ADEBAYO John Oluwafemi OYEYEMI Adekunle Wahab ADEOLA Iyabo Cecilia AYANWOLE Elizabeth Tope JEGEDE Febisola Oluwatoyin OGUNSAKIN Ruth Oluwakemi Integrative Biology Unit Transcriptional Regulation Group International Centre for Genetic Engineering and Biotechnology department of Science Technology The Federal Polytechnic Ado-Ekiti department of physiology Igbinedion university

The ratio of the second-to-fourth digit length（2D：4D）has been shown to be sexually dimorphic,with males having lower mean than females and the ratio relates to masculinity and femininity in adults.2D：4D is influenced by digit growth pattern which is related to the ratio of prenatal androgen to estrogen levels in the later part of the first trimester.

关键词： WC WHR Second to Fourth Digit Ratio BMI NC FSH

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A Simple and Rapid Oxidative Stress Screening Method of Small Molecules for Functional Studies of Transcription Factor

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Rice science 2022年第5期29卷 402-406,I0012-I0016页

作者： Vanitha ADHINARAYANREDDY Preethi VIJAYARAGHAVAREDDY Ashwin VARGHEESE Sujitha DADI Akshay UTTARKAR Vidya NIRANJAN Anuradha VENKATRAMAN Sheshshayee M.SREEMAN Ramu S.VEMANNA Laboratory of Plant Functional Genomics Regional Centre for BiotechnologyFaridabad-Gurgaon ExpresswayFaridabad 121001India department of Crop physiology University of Agricultural SciencesBengaluru 560065India department of biotechnology Rashtreeya VidyalayaCollege of EngineeringBengaluru 560059India department of Biochemistry&biotechnology Annamalai UniversityChidambaram 608002India

Structure-assisted reverse chemical discovery approaches are becoming attractive due to target based ***,Small molecules(SMs)identified by reverse chemical genetic approach require robust phenotyping assays to study the plant *** optimized a screening method in rice seedlings using methyl viologen(MV)induced oxidative stress under high light *** method was suitable for studying the efficacy of SM targeting oxidative stress related ***-assisted drug designing approach was used to identify SM targeting DREB2A transcription factor(TF).Rice seedlings treated with pronetalol showed susceptible phenotype when exposed to oxidative *** inhibited the DREB2A activity and suppressed the expression of its target LEA7 and HSFA3 genes under oxidative *** assay is quite simple and robust and can be expanded to high throughput screening method for functional validation of TF.

关键词： inhibited oxidative Small

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Expression of Acyl-lipid 12-desaturase Gene in Prokaryotic and Eukaryotic Cells and Its Effect on Cold Stress Tolerance of Potato

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Journal of Integrative Plant Biology 2010年第3期52卷 289-297页

作者： Reza Maali Amiri Natalia O. Yur'eva Khristina R. Shimshilashvili Irina V. Goldenkova-Pavlova Vasiliy P. Pchelkin Elmira I. Kuznitsova Vladimir D. Tsydendambaev Tamara I. Trunova Dmitry A. Los Gholamreza Salehi Jouzani Alexander M. Nosov department of Agronomy and Plant Breeding University College of Agriculture and Natural Resources of the University of Tehran K.A.Timiryazev Institute of Plant physiology Russian Academy of Sciences (RAS) Vavilov Institute of General Genetics Agricultural biotechnology Researches Institute of Iran (ABRII) department of Plant physiology Moscow State University

We report the expression profile of acyl-lipid △12-desaturase （desA） gene from Synechocystis sp. PCC6803 and its effect on cell membrane lipid composition and cold tolerance in prokaryotic （Escherichia coil） and eukaryotic （Solanum tuberosum） cells. For this purpose, a hybrid of desA and reporter gene encoding thermostable lichenase （licBM3） was constructed and used to transform these cells. The expression of this hybrid gene was measured using qualitative （Petri dish test, electrophoregram and zymogram） and quantitative methods （spectrometry and gas liquid chromatography assays）. The maximum level of linoleic acid in the bacterial cells containing hybrid gene was 1.9% of total fatty acids. Cold stress tolerance assays using plant damage index and growth parameters showed that cold tolerance was enhanced in primary transgenic lines because of increased unsaturated fatty acid concentration in their lipids. The greatest content of 18：2 and 18：3 fatty acids in primary transgenic plants was observed for lines 2 （73%） and 3 （41%）. Finally, our results showed that desaturase could enhance tolerance to cold stress in potato, and desaturase and lichenase retain their functionality in the structure of the hybrid protein where the enzymatic activity of target gene product was higher than in the case of reporter lichenase gene absence in the construction.

关键词： Expression of Acyl-lipid 12-desaturase Gene in Prokaryotic and Eukaryotic Cells and Its Effect on Cold Stress Tolerance of Potato gene

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A review: The beneficial effects and possible mechanisms of aluminum on plant growth in acidic soil

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Journal of Integrative Agriculture 2019年第7期18卷 1518-1528页

作者： Noor Muhammad Gerald Zvobgo ZHANG Guo-ping department of Agronomy College of Agriculture and BiotechnologyZhejiang UniversityHangzhou 310058P.R.China physiology/Chemistry Section Central Cotton Research InstituteMultan 60500Pakistan

Aluminum(Al) is the third most abundant element in the earth’s crust and a major factor inhibiting plant growth and reducing crop yield in acidic *** there is substantial research on the phytotoxic effects and the underlying mechanisms of Al by applying Al alone hydroponically,soil is a complex medium containing numerous mineral elements that can interact with Al and other elements and their bioavailability in *** this review,we describe the roles of Al in promoting plant growth,enhancing phosphorus availability and efficient use in plants,and alleviating H+,iron,and manganese toxicity in acidic ***,we discuss the possible mechanisms of enhanced abiotic stress tolerance induced by *** also elucidate the role of Al in attracting plant growth promoting rhizo-bacteria(PGPR) and their interactions with plants by increasing organic exudates.

关键词： aluminum interaction iron manganese organic acids phosphorous tolerance

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ZmGns,a maize class I β-1,3-glucanase,is induced by biotic stresses and possesses strong antimicrobial activity

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Journal of Integrative Plant Biology 2015年第3期57卷 271-283页

作者： Yu-Rong Xie Yenjit Raruang Zhi-Yuan Chen Robert L.Brown Thomas E.Cleveland department of Plant Pathology and Crop physiology Louisiana State University Agricultural Center biotechnology Research Institute the Chinese Academy of Agricultural Sciences Southern Regional Research Center USDA-ARS

Plant b-1,3-glucanases are members of the pathogenesis-related protein 2（PR-2） family,which is one of the 17 PR protein families and plays important roles in biotic and abiotic stress *** of the differentially expressed proteins（spot 842） identified in a recent proteomic comparison between five pairs of closely related maize（Zea mays L.） lines differing in aflatoxin resistance was further investigated in the present ***,the corresponding cDNA was cloned from maize and designated as *** encodes a protein of338 amino acids containing a potential signal *** expression of Zm Gns was detectible in all tissues studied with the highest level in *** was significantly induced by biotic stresses including three bacteria and the fungus Aspergillus *** was also induced by most abiotic stresses tested and growth hormones including salicylic *** vivo,ZmGns showed a significant inhibitory activity against thebacterial pathogen Pseudomonas syringae *** DC3000 and fungal pathogen Botrytis cinerea when it overexpressed in *** high level of expression in the silk tissue and its induced expression by phytohormone treatment,as well as by bacterial and fungal infections,suggest it plays a complex role in maize growth,development,and defense.

关键词： β-1 3-Glucanase biological activity expression profiles Zea mays ZmGns

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Effect of Korea red ginseng on cerebral blood flow and superoxide production

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Acta Pharmacologica Sinica 2002年第12期23卷 99-103页

作者： CukSeong KIM,Jin Bong PARK,Kwang-Jin KIM,Seok Jong CHANG,Sung-Woo RYOO,Byeong Hwa JEON department of physiology College of Medicine Chungnam National University Taejon KOREA department of physiology College of Medicine Chungnam National University Taejon KOREA department of physiology College of Medicine Chungnam National University Taejon KOREA department of physiology College of Medicine Seonam University Namwon KOREA Division of Genomics ＆ Proteomics Korea Research Institute of Bioscience and biotechnology(KRIBB) Yusong Taejon Korea Correspondence to Byeong Hwa JEON MD PhD.department of physiology College of Medicine Chungnam National University 6 Munhwa-dong Jung-gu Taejon South Korea 301131

AIM: To investigate the effects of Korea red ginseng (KRG) on the cerebral perfusion rate in the rats and the generation of superoxide anion in the endothelial cells. METHODS: The cerebral perfusion rate was measured using laser-doppler flowmetry before and after the administration of crude saponin (CS) and saponin-free fraction (SFF) of KRG in the anesthetized rats. The superoxide generation was measured by the method based on lucigenin-enhanced chemiluminescence in the cultured endothelial cells. RESULTS: The relative cerebral perfusion rate (rCBF) was significantly increased by the intraperitoneal injection of CS (100 mg/kg) in the rats, but SFF had no effect on the rCBF. Chronic treatment with CS for 7 d significantly inhibited the decrease of forebrain cerebral blood flow induced by clamping both carotid arteries in the rats. Furthermore, CS (0.1 g/L) significantly sup-pressed NADPH-induced superoxide generation in the human umbilical vein endothelial cells (P<0.01). CONCLUSION: The present study d

关键词： Korean red ginseng cerebral blood flow superoxides vascular endothelium

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