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Enemies atpeace:Recentprogressin Agrobacterium-mediated cereal transformation

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The Crop Journal 2024年第2期12卷 321-329页

作者： Shaoshuai Liu Ke Wang Shuaifeng Geng Moammar Hossain Xingguo Ye Aili Li Long Mao Karl-Heinz Kogel State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Institute of Phytopathology Centre for BioSystemsLand Use and NutritionJustus Liebig UniversityHeinrich Buff-Ring 26-32D-35392GiessenGermany

Agrobacterium tumefaciens mediated plant transformation is a versatile tool for plant genetic engineering following its discovery nearly half a century *** modifications were made in its application to increase efficiency,especially in the recalcitrant major cereals *** breakthroughs in transformation efficiency continue its role as a mainstream technique in CRISPR/Cas-based genome editing and gene *** modifications led to higher transformation frequency and lower but more stable transgene copies with the capability to revolutionize modern *** this review,we provide a brief overview of the history of Agrobacterium-mediated plant transformation and focus on the most recent progress to improve the system in both the Agrobacterium and the host recipient.A promising future for transformation in biotechnology and agriculture is predicted.

关键词： Agrobacterium tumefaciens Cereal species Genome editing Genetic engineering Plant breeding

Miniature tunable Airy beam optical meta-device

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Opto-Electronic Advances 2024年第2期7卷 5-12页

作者： Jing Cheng Zhang Mu Ku Chen Yubin Fan Qinmiao Chen Shufan Chen Jin Yao Xiaoyuan Liu Shumin Xiao Din Ping Tsai Department of Electrical Engineering City University of Hong KongKowloonHong Kong SAR 999077China State Key Laboratory of Terahertz and Millimeter Waves City University of Hong KongKowloonHong Kong SAR 999077China centre for biosystems Neuroscienceand NanotechnologyCity University of Hong KongKowloonHong Kong SAR 999077China Ministry of Industry and Information Technology Key Lab of Micro-Nano Optoelectronic Information System Guangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic SystemsHarbin Institute of TechnologyShenzhen 518055China

Tunable Airy beams with controllable propagation trajectories have sparked interest in various fields,such as optical manipulation and laser *** research approaches encounter challenges related to insufficient compactness and integration feasibility,or they require enhanced tunability to enable real-time dynamic manipulation of the propagation *** this work,we present a novel method that utilizes a dual metasurface system to surpass these limitations,significantly enhancing the practical potential of the Airy *** approach involves encoding a cubic phase profile and two off-axis Fresnel lens phase profiles across the two *** validity of the proposed strategy has been confirmed through simulation and experimental *** proposed meta-device addresses the existing limitations and lays the foundation for broadening the applicability of Airy beams across diverse domains,encompassing light-sheet microscopy,laser fabrication,optical tweezers,etc.

关键词： metasurface miniature device tunable Airy beam tunable meta-device

Advanced manufacturing of dielectric metadevices

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Photonics Insights 2024年第2期3卷 31-70页

作者： Wenhong Yang Junxiao Zhou Din Ping Tsai Shumin Xiao Key Lab of Micro-Nano Optoelectronic Information System Ministry of Industry and Information TechnologyGuangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic SystemsHarbin Institute of TechnologyShenzhenChina Department of Electrical Engineering City University of Hong KongHong KongChina The State Key Laboratory of Terahertz and Millimeter Waves City University of Hong KongHong KongChina centre for biosystems Neuroscienceand NanotechnologyCity University of Hong KongHong KongChina Pengcheng Laboratory ShenzhenChina

Metasurfaces,composed of two-dimensional nanostructures,exhibit remarkable capabilities in shaping wavefronts,encompassing phase,amplitude,and *** unique proficiency heralds a transformative paradigm shift in the domain of next-generation optics and photonics,culminating in the development of flat and ultrathin optical *** noteworthy is the all-dielectric-based metasurface,leveraging materials such as titanium dioxide,silicon,gallium arsenide,and silicon nitride,which finds extensive application in the design and implementation of high-performance optical devices,owing to its notable advantages,including a high refractive index,low ohmic loss,and ***,the remarkable growth in nanofabrication technologies allows for the exploration of new methods in metasurface fabrication,especially through wafer-scale nanofabrication technologies,thereby facilitating the realization of commercial applications for *** review provides a comprehensive overview of the latest advancements in state-of-the-art fabrication technologies in dielectric metasurface *** technologies,including standard nanolithography[e.g.,electron beam lithography(EBL)and focused ion beam(FIB)lithography],advanced nanolithography(e.g.,grayscale and scanning probe lithography),and large-scale nanolithography[e.g.,nanoimprint and deep ultraviolet(DUV)lithography],are utilized to fabricate highresolution,high-aspect-ratio,flexible,multilayer,slanted,and wafer-scale all-dielectric metasurfaces with intricate ***,we conclude with a perspective on current cutting-edge nanofabrication technologies.

关键词： dielectric meta-devices meta-optics metasurface nanofabrication nanotechnology nanophotonics large/waferscale nanofabrication

Recent antibacterial agents from biomass derivatives:Characteristics and applications

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Journal of Bioresources and Bioproducts 2024年第3期9卷 283-309页

作者： Nissa Nurfajrin Solihat Alif Faturahman Hidayat R.A.Ilyas Senthil Muthu Kumar Thiagamani Nur Izyan Wan Azeele Fahriya Puspita Sari Maya Ismayati Mohammad Irfan Bakshi Zaharaddeen N.Garba M.Hazwan Hussin Witta Kartika Restu Wasrin Syafii Harits Atika Ariyanta Widya Fatriasari Research Center for Biomass and Bioproducts National Research and Innovation Agency(BRIN)Kawasan KST SoekarnoJl Raya Bogor KM 46 Cibinong Bogor 16911Indonesia Department of Bioproducts and biosystems School of Chemical EngineeringAalto UniversityEspoo 16300Finland Department of Chemical Engineering Faculty of Chemical and Energy EngineeringUniversiti Teknologi MalaysiaJohor 81310Malaysia centre for Advanced Composite Materials Universiti Teknologi MalaysiaJohor 81310Malaysia Institute of Tropical Forestry and Forest Products Universiti Putra MalaysiaSerdang 43400Malaysia centre of Excellence for Biomass Utilization Universiti Malaysia PerlisPerlis 02600Malaysia Department of Mechanical Engineering Kalasalingam Academy of Research and EducationKrishnankoil 626126India Institute of Bioproduct Development(IBD) Universiti Teknologi MalaysiaJohor 81310Malaysia Department of Chemistry Ahmadu Bello UniversityZaria 810211Nigeria Materials Technology Research Group(MaTReC) School of Chemical SciencesUniversiti Sains MalaysiaMinden 11800Malaysia Research Center for Chemistry National Research and Innovation Agency(BRIN)Kawasan Puspiptek SerpongSouth Tangerang 15314Indonesia Department of Forest Products Faculty of Forestry and EnvironmentIPB UniversityBogor 16680Indonesia Department of Pharmacy Gunadarma UniversityDepok 16424Indonesia Research Collaboration Center of Biomass-Based Nano Cosmetic In collaboration with National Research and Innovation Agency(BRIN)SamarindaEast KalimantanIndonesia

Enhancing awareness of personal cleanliness and antibacterial resistance has intensified the antibacterial substance request on consumable products. Antibacterial agents that have been commercialized nowadays are produced from inorganic and non-renewable substances. This provides several drawbacks, particularly against health and environmental issues. Therefore, many scientists work on substituting fossil-fuel-based antibacterial agents with natural ones such as from biomass. Biomass derivatives, natural abundances of biopolymers in the world, amount to major compounds including polysaccharides (cellulose, hemicellulose, and chitosan) and polyphenol (tannin and lignin) substances which are capable to combat the growth of Gram-positive bacteria and Gram-negative bacteria. To date, no report focuses on a deep understanding of antibacterial properties derived from biomass and the internal and external factors effects. This work provides that gap because comprehensive knowledge is necessary before applying biomass to the products. The potency of biomass derivatives as antibacterial additives is also summarized. Basic knowledge of antibacterial characteristics to the application in products is highlighted in this review. Besides, the discussion about challenges and future perspectives is also delivered.

关键词： Antibacterial Application Biomass derivatives Challenge Future perspectives

Structure-function Aspects of Extracellular Leucine-rich Repeat-containing Cell Surface Receptors in Plants

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Journal of Integrative Plant Biology 2013年第12期55卷 1212-1223页

作者： Zhao Zhang Bart P.H.J.Thomma Laboratory of Phytopathology Wageningen University centre for biosystems Genomics

Plants exploit several types of cell surface receptors for perception of extracellular signals, of which the extracellular leucine-rich repeat （eLRR）-containing receptors form the major class. Although the function of most plant eLRR receptors remains unclear, an increasing number of these receptors are shown to play roles in innate immunity and a wide variety of developmental processes. Recent efforts using domain swaps, gene shuffling analyses, site-directed mutagenesis, interaction studies, and crystallographic analyses resulted in the current knowledge on ligand binding and the mechanism of activation of plant eLRR receptors. This review provides an overview of eLRR receptor research, specificallysummarizing the recent understanding of interactions among plant eLRR receptors, their co-receptors and corresponding ligands. The functions of distinct eLRR receptor domains, and their role in structure, ligand perception and multimeric complex formation are discussed.

关键词： eLRR receptor-like kinase (RLK) receptor-like protein (RLP) pathogen-associated molecular pattern (PAMP) effector peptide ligand brassinosteroid CLE peptide.

Molecular Diagnosis of Sexual Differentiation Disorders in Burkina Faso

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Journal of Biosciences and Medicines 2024年第3期12卷 1-15页

作者： Bazie Bapio Valérie Elvira Jean Télesphore Sawadogo Soumaïla Zohoncon Théodora Mahoukèdè Tall Ahmadou Bado Prosper Soubeiga Serge Théophile Ouattara Moussa Sorgho Abel Kiendrebeogo Touwendpoulimdé Isabelle Yonli Albert Theophane Djigma Florencia Millogo/Traore Timongo Françoise Danielle Simpore Jacques centre National de la Recherche Scientifique et Technologique (CNRST) Institut de Recherche en Sciences de la Santé (IRSS) Ouagadougou Burkina Faso Université Joseph KI-ZERBO Unité de Formation en Sciences de la Vie et de la Terre Laboratoire de Biologie Moléculaire et de Génétique (LABIOGENE) Ouagadougou Burkina Faso centre de Recherche Biomoléculaire Pietro Annigonie (CERBA) Ouagadougou Burkina Faso centre Hospitalier Universitaire Régional de Ouahigouya Ouagadougou Burkina Faso centre Hospitalier Universitaire Yalgado Ouedraogo Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

Sex development anomalies represent a group of congenital pathologies in which chromosomal, gonadal and anatomical sex differentiation is atypical. The aim of our study was to use molecular biology techniques to elucidate sex in cases of anomalies of sexual differentiation in Burkina Faso. This cross-sectional study took place from March 2023 to June 2023. Oral and blood samples were collected respectively using sterile swabs and stored on Swab Kits and NUCLEIcardTM (https://***/product-ranges/nucleic-card/) were used to determine gonosome profiles. Extraction was carried out using the DNA Swap solution Kit and the DNA IQ System Kit, and a PowerPlex? 21 kit (Promega) for amplification. The Applied biosystems 9700 thermal cycler was used for PCR followed by 36 cm capillary electrophoresis in the Applied biosystems 3130 prism sequencer. Sequence files were analyzed using GeneMapper IDX v. 3.2 software. Seven (07) patients were registered during the study period. There were 4 cases of XX DSD or 46, XX DSD and 3 cases of XY DSD or 46, XY DSD. The median age of our patients was 16 years. Civilian sex was male in 4 cases and female in 3. The most frequent reason for consultation was micropenis in 3 cases, followed by primary amenorrhea and sex ambiguity. There were 03 cases of discrepancy between genetic sex and civil sex. The accessibility of molecular diagnosis is little known to clinicians. XX DSDs or 46, XX DSDs were the most frequent (4/7) in our study. The problem facing this situation is early diagnosis to help prevent complications in Burkina Faso.

关键词： Gonosome DSD Abnormal Sexual Development Burkina Faso

Integrated-resonant metadevices:a review

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Advanced Photonics 2023年第2期5卷 7-33页

作者： Jin Yao Rong Lin Mu Ku Chen Din Ping Tsai City University of Hong Kong Department of Electrical EngineeringHong KongChina City University of Hong Kong Centre for BiosystemsNeuroscienceand NanotechnologyHong KongChina City University of Hong Kong State Key Laboratory of Terahertz and Millimeter WavesHong KongChina

Integrated-resonant units(IRUs),associating various meta-atoms,resonant modes,and functionalities into one supercell,have been promising candidates for tailoring composite and multifunctional electromagnetic responses with additional degrees of ***-resonant metadevices can overcome many bottlenecks in conventional optical devices,such as broadband achromatism,efficiency enhancement,response selectivity,and continuous tunability,offering great potential for performant and versatile application *** focus on the recent progress of integrated-resonant *** from the design principle of IRUs,a variety of IRU-based characteristics and subsequent practical applications,including achromatic imaging,light-field sensing,polarization detection,orbital angular momentum generation,metaholography,nanoprinting,color routing,and nonlinear generation,are *** challenges in this field and opinions on future research directions are also provided.

关键词： integrated-resonant units metadevices metasurfaces nanophotonic devices planar optics

Templating core-shell particles using metal ion-chelating biosurfactants

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Particuology 2022年第5期20卷 145-152页

作者： Ching-Min Yeh Thomas Jarrett Yuan Gao Chun-Xia Zhao Andrew Whittaker Frank Sainsbury Alison L.White Australian Institute of Bioengineering and Nanotechnology The University of QueenslandSt.LuciaQueensland4072Australia ARC centre of Excellence in Convergent Bio-Nano Science and Technology The University of QueenslandSt Lucia4072Australia CSIRO Probing biosystems Future Science Platform BrisbaneAustralia centre for Cell Factories and Biopolymers Griffith Institute for Drug DiscoveryGriffith UniversityBrisbaneQLD4111 Australia

Designer biosurfactants can be used to stabilise and functionalise *** particularly promising use is the stabilisation of oil-in-water emulsions,enabling fine tuning physical,chemical and biological surface *** ability of emulsion systems to carry high payloads makes them attractive for applications in medicine,food and fragrances,and ***,they have limited long-term *** we sought to use the metal ion-chelating ability of the biosurfactant peptide,AM1,to precipitate the formation of a gold metal shell on AM1-stabilised emulsions by electroless *** found that replacing the commonly used zinc(Ⅱ)with palladium(Ⅱ)for coordination by histidine residues of adjacent AM1 peptides produced interfacial films that maintained elasticity at acidic *** NMR suggested a coordination mechanism independent of the imidazole ring of the *** of emulsions at low pH enabled the deposition of a gold shell,albeit by an unexpected *** propose that gold nanoparticles forming in bulk are adsorbed onto the peptide-stabilised interface,accumulating into a particulate *** resulting one-step method for nanoparticle precipitation and shell formation will be useful for the creation of biocompatible core-shell particles for applications where large payloads of hydrophobic active compounds require stability over long time periods.

关键词： Biosurfactants Emulsion Core-shell particles Electroless plating Histidine Interfacial elasticity

Therapeutic cell engineering:designing programmable synthetic genetic circuits in mammalian cells

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Protein & Cell 2022年第7期13卷 476-489页

作者： Maysam Mansouri Martin Fussenegger Department of biosystems Science and Engineering ETH ZurichMattenstrasse 264058 BaselSwitzerlandDepartment of Biosystems Science and EngineeringETH ZurichMattenstrasse 264058 BaselSwitzerland Faculty of Science University of BaselMattenstrasse 264058 BaselSwitzerland

Cell therapy approaches that employ engineered mam-malian cells for on-demand production of therapeutic agents in the patient's body are moving beyond proof-of-concept in translational *** therapeutic cells can be customized to sense user-defined signals,pro-cess them,and respond in a programmable and pre-dictable *** this paper,we introduce the available tools and strategies employed to design therapeutic ***,various approaches to control cell behav-iors,including open-loop and closed-loop systems,are *** also highlight therapeutic applications of engineered cells for early diagnosis and treatment of various diseases in the clinic and in experimental dis-ease ***,we consider emerging technolo-gies such as digital devices and their potential for incorporation into future cell-based therapies.

关键词： synthetic biology cell-based therapy cell engineering therapeutic gene expression controllable genetic circuits