Does astrocytic L-lactate enhance cognition through myelination?

作     者：Mastura Akter Ying Li Mastura Akter;Ying Li

作者机构：Department of Neuroscience City University of Hong Kong Department of Biomedical Sciences City Universit of Hong Kong Centre for Regenerative Medicine and Health Hong Kong Institute of Science & Innovation Chinese Academy of Sciences Centre for Biosystems Neuroscience and Nanotechnology City University of Hong Kong 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究(英文版))

年 卷 期：2024年第19卷第6期

页      面：1167-1168页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 071006[理学-神经生物学] 

基　　金：funded by the General Research Fund (GRF) of the Research Grants Council of Hong Kong,China (11103721, 11102820, and 11100018) the National Natural Science Foundation of China (NSFC) and RGC Joint Research Scheme (3171101014, N＿CityU114/17) the Innovation and Technology Fund Hong Kong,China (CityU 9445909)(all to YL) supported by a grant from City University of Hong Kong Neuroscience Research Infrastructure (9610211) a grant from Center for Biosystems Neuroscience,and Nanotechnology (9360148)(both to YL) 

摘      要：Introduction: Astrocytes, the predominant glial cell in the brain, play a vital role in a plethora of central ner vous system functions. They are the major storage site of glycogen in the central nervous system. They produce L-lactate by glycogenolysis and glycolysis which is then transported to neurons(Magistreti and Allaman,