检索结果-南通市图书馆

Prenatal programing of motivated behaviors:can innate immunity prime behavior?

Neural Regeneration Research 2023年第2期18卷 280-283页

作者： Larisa Montalvo-Martínez Gabriela Cruz-Carrillo Roger Maldonado-Ruiz Luis ATrujillo-Villarreal Eduardo AGarza-Villarreal Alberto Camacho-Morales Universidad Autónoma de Nuevo León Department of BiochemistryCollege of MedicineMonterreyMéxico Universidad Autónoma de Nuevo León Neurometabolism UnitCenter for Research and Development in Health SciencesMonterreyMéxico Universidad Nacional Autónoma de México Campus Juriquilla Instituto de NeurobiologíaQueretaroMéxico

Prenatal programming during pregnancy sets physiological outcomes in the offspring by integrating external or internal stimuli.Accordingly,pregnancy is an important stage of physiological adaptations to the environment where the fetus becomes exposed and adapted to the maternal milieu.Maternal exposure to high-energy dense diets can affect motivated behavior in the offs p ring leading to addiction and impaired sociability.A high-energy dense exposure also increases the pro-inflammatory cytokines profile in plasma and brain and favors microglia activation in the offspring.While still under investigation,prenatal exposure to high-energy dense diets promotes structural abnormalities in selective brain regions regulating motivation and social behavior in the offspring.The current review addresses the role of energy-dense foods programming central and peripheral inflammatory profiles during embryonic development and its effect on motivated behavior in the offspring.We provide preclinical and clinical evidence that supports the contribution of prenatal programming in shaping immune profiles that favor structural and brain circuit disruption leading to aberrant motivated behaviors after birth.We hope this minireview encourages future research on novel insights into the mechanisms underlying maternal programming of motivated behavior by central immune networks.

关键词： addiction autism behavior cytokines diet maternal immune activation prenatal programming sociability trained immunity western-diets

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis and characterization of nano-hydroxyapatite added with magnesium obtained by wet chemical precipitation

引用

Progress in Natural Science:Materials International 2021年第4期31卷 575-582页

作者： Brandon A.Correa-Pi?a Omar M.Gomez-Vazquez Sandra M.Londo?o-Restrepo Luis F.Zubieta-Otero Beatriz M.Millan-Malo Mario E.Rodriguez-García Posgrado en Ciencia e Ingeniería de Materiales Centro de Física Aplicada y Tecnología Avanzada Universidad Nacional Autónoma de México Campus Juriquilla Departamento de Nanotecnología Centro de Física Aplicada y Tecnología Avanzada Universidad Nacional Autónoma de México Campus Juriquilla

Biogenic hydroxyapatites from mammalian bones naturally contain traces of ions, like Mg, which play a vital role in the bone remodeling process. In this way, synthetic hydroxyapatites should include this kind of mineral. In this work, hydroxyapatite added with Mg was synthesized by wet precipitation using（NH;）H;PO;, Ca（NO;）;.4 H;O,and Mg（NO;）;.6 H;O（0, 0.032, 0.061, and 0.123 M）. Inductively coupled plasma and X-ray diffraction evidenced the Mg inclusion in the hydroxyapatite lattice in the same levels reported for natural hydroxyapatites. The calcination at 600℃ was performed to remove the reaction by-products, but it also gave rise to physicochemical changes as the coalescence and crystals recrystallization. It produced, in turn, an improvement in the crystalline quality, according to Raman analysis. Despite those physicochemical changes, all the samples remained nanometric according to scanning electron microscopy imaging.

关键词： Magnesium Physicochemical properties Calcination Nanometric crystal size Coalescence Recrystallization

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Effects of Pre-and Neonatal Undernutrition on Long-Term Hearing Cognition of the Rat

引用

Journal of Behavioral and Brain Science 2022年第6期12卷 302-322页

作者： Manuel Salas Carmen Torrero Mirelta Regalado Institute of Neurobiology Department of Developmental Neurobiology and Neurophysiology Universidad Nacional Autónoma de México Campus UNAM Juriquilla Querétaro México

Experimental evidence in the rat suggests that perinatal undernutrition, associated with sensory and hormonal deficiencies, interferes with brain network integrative actions. We review peripheral and central morpho-functional alterations related to early food restriction along with the auditory relays, and their connections with the limbic system, which are essential for motivation-emotional arousal. The findings indicated that different morpho-functional alterations in the auditory system permanently affect the brainstem, the reticular thalamic nucleus, and the prefrontal and auditory cortices. Moreover, data showed the noxious role of early food restriction and the external ear occlusion on the distal portions of dendritic arbor measurements, in the cochlea, nucleus ambiguous and motor cortical pyramids. These anatomical alterations also correlated with deficiencies in the dynamic motor and auditory cognitive brain plasticity. Food restriction-related deficiencies in the motor-emotional-behavioral arousal systems may be useful to understand long-term cognitive disorders in humans.

关键词： Perinatal Undernutrition Auditory Cognition Mother-Litter Bonds Rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Estradiol on 5-HTsA and 5-HT2c Receptor Immunolabeling in Rat Hippocampus

引用

Journal of Life Sciences 2011年第11期5卷 884-889页

作者： Laura Cristina Berumen Marco Antonio Sainchez-Ramos Martin Garcla-Servin Ataulfo Martinez-Torres Angelina Rodriguez Guadalupe Garcla-Alcocer Facultad de Quimica Universidad A utonoma de Querotaro Centro Universitario Queretaro 76010 Mexico Facultad de Ciencias Naturales Universidad Autonoma de Queretaro Campus Juriquilla Juriquilla Queretaro 76230 Mexico Department of Cellular and Molecular Neurobiology Instituto de Neurobiologia Universidad Nacional Autonoma de Mexico Campus Juriquilla Juriquilla Queretaro 76230 Mexico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analysis of Key Features of Non-Linear Behavior Using Recurrence Plots. Case Study: Urban Pollution at Mexico City

引用

Journal of Environmental Protection 2012年第9期3卷 1147-1160页

作者： Marco A. Aceves-Fernandez Jesus Carlos Pedraza-Ortega Artemio Sotomayor-Olmedo Juan M. Ramos-Arreguín Jose Emilio Vargas-Soto Saul Tovar-Arriaga campus juriquilla Universidad Autonoma de Queretaro Santiago de Querétaro México

The use of Recurrence plots have been extensively used in various fields. In this work, Recurrence Plots (RPs) investigates the changes in the non-linear behaviour of urban air pollution using large datasets of raw data (hourly). This analysis has not been used before to extract information from large datasets for this type non-linear problem. Two different approaches have been used to tackle this problem. The first approach is to show results according to monitoring network. The second approach is to show the results by particle type. This analysis shows the feasibility of using Recurrence Analysis for pollution monitoring and control.

关键词： Recurrence Plot Air Quality Air Pollution Modelling Atmospheric Pollution Recurrence Quantification Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Juvenile Play Behavior in Neonatally Underfed and Sensory Stimulated Wistar Rats

引用

Journal of Behavioral and Brain Science 2019年第10期9卷 362-374页

作者： Manuel Salas Mirelta Regalado Carmen Torrero Minerva Ortiz-Valladares Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology University of Mexico Campus UNAM Juriquilla Queretaro Mexico

Play development in juvenile rats depends on specific sensory signals integrated at cortical, limbic and brain stem levels to modulate motoric, metabolic, motivational and social responses. Neonatal undernourishment disrupts the morphological and functional organization of the brain for adaptive responses including play performance. These alterations may be restored by preweaning exposure to sensory-enriched environments. This study was designed to determine in four experimental groups, Control (LC), Underfed (LU), Control Ligated/Stimulated (LCS), and Underfed Ligated/Stimulated (LUS), whether changes in juvenile play of neonatally underfed male rats by the nipple-ligated procedure of F0 dams and/or the handling of F1 rats may restore the deficiencies in juvenile play performance. The pinning frequency values in LC, LCS and LUS groups consistently increased until reaching a significant peak between postnatal days (PDs) 25 and 50 and then gradually declining until PD 60, when the play in pairs was significantly higher compared with the play in groups that follows the same sequence but with lower values in the stimulated groups. The results may reflect poor maternal care and lower somatosensory stimulation;and the sensory massage of LU F1 pups compared with the LC, LUS, and LCS rats. Fewer dorsal body contacts occurred in LU and LUS rats when playing in pairs than in groups. Results suggest that although handling has salutary effects on neuronal play structures, the reduced levels of total pinning and dorsal contacts, mainly in the play of rat pairs in LCS vs. LUS groups, were not fully recovered.

关键词： Juvenile Play Early Handling Neonatal Undernutrition Rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Perinatal Undernutrition and Massage Stimulation upon the Ambiguus Nucleus in the Rat Prior to Weaning

引用

Journal of Behavioral and Brain Science 2013年第2期3卷 200-209页

作者： Dora Lopez-Jimenez Carmen Torrero Mirelta Regalado Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology National Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico Department of Developmental Neurobiology and Neurophysiology Institute of NeurobiologyNational Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico

Undernutrition produces morphological brain alterations and cognitive deficiencies in children of underdeveloped countries. The central nervous system (CNS) alterations mainly interfere with the anatomical organization of areas undergoing a phase of intense postnatal cell proliferation, disrupting plastic processes like learning, memory, and phonation. In the rat pup, prenatal malnutrition interferes with the elaboration of ultrasonic vocalizations (USVs) by poorly understood mechanisms. The neuronal caudal portion of the nucleus ambiguus (Ambc) innervates the laryngeal intrinsic muscles to produce phonation, a basic USV communication system. During postnatal development, enhanced plasticity phenomena play a fundamental role in improving brain function. Thus, the massage stimulation (MS) may accelerate growth and induce neurogenesis in different areas of the brain. The current study analyzed the effects of a daily 10-min MS on the dendritic tree and perikarya measurements of Ambc multipolar motoneurons (Golgi-Cox) of perinatally underfed (U), control (C), control massage-stimulated (CMS), and underfed massage-stimulated (UMS) groups at postnatal days (PDs) 8, 12, and 15. The data indicated that the dendritic scores were reduced (p < 0.05) in both number and density at PD8 and PD15 in the U subjects and that MS increased the values of these parameters (p < 0.05). In addition, MS induced body weight gain in both U and CMS groups, and it enhanced the dendritic density in CMS subjects. These results show that MS during the pre-weaning period restores the plastic properties of the Ambc over the hypoplastic multipolar motoneuron after the alterations caused by perinatal undernutrition.

关键词： Nucleus Ambiguus Development Massage Stimulation Perinatal Undernutrition Rat Pups

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Correcting the Gutenberg–Richter b-value for effects of rounding and noise

引用

Earthquake Science 2015年第2期28卷 129-134页

作者： V.H.Márquez-Ramírez F.A.Nava F.R.Zúiga UNAM campus Querétaro México Centro de GeocienciasBlvd.Juriquilla No 3001 76230 México Querétaro México Seismology Department CICESE Carretera Ensenada-Tijuana No 3918 Zona Playitas 22860 Ensenada BC México

The effects of magnitude rounding and of the presence of noise in the rounded magnitudes on the estimation of the Gutenberg-Richter b-value are explored, and the ways to correct for these effects are proposed. For typical values, b = 1 and rounding interval △M = 0.1, the rounding error is approximately -10^-3 and it can be corrected to a negligible approximately -10^-5. For the same typical values, the effect of noise can be larger, depending on the characteristics of the noise distribution; for normally distributed noise with standard deviation σ = 0.1, the correct b-value may be underestimated by a factor - 0.97.

关键词： b-Value Noise Magnitude

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Olfactory Discrimination in Adult Male Rats Undernourished during the Pre- and Neonatal Period

引用

Journal of Behavioral and Brain Science 2012年第3期2卷 283-290页

作者： Mitzi G. Carreon Carmen Torrero Mirelta Regalado Lorena Rubio Manuel Salas Developmental Neurobiology and Neurophysiology Department Neurobiology Institute University of Mexico Campus UNAM Juriquilla Queretaro Mexico

In the neonatal rat, the olfactory system is a fundamental channel to locate and recognize the mother, to survive and develop early social behavior, and to distinguish related or unrelated members of a litter. Perinatal undernutrition in rats alters the neuronal organization and functioning of the olfactory system and its ascending relays, possibly affecting odor discrimination. In this study we compared the frequency and time spent visiting the source of urine obtained from unrelated female subjects and amyl acetate odors vs water in adult perinatally underfed rats. Each test initiated with one daily presentation during three consecutive aliquots of deionized water (10 μl) placed on a filter paper for 2 min, separated by 1-min intervals for habituation. The water presentations were followed by three exposures to an odor, all at the same dilution (either 1:1 or 1:80) for dishabituation. Control (C) and undernourished (U) subjects display similar, significant habituation/dishabituation responses, except that the U subjects showed greater increases in the frequency and duration of visits to undiluted and diluted urine and amyl acetate cues compared to the controls. These findings are similar to previous studies showing that adult rats investigate novel odors longer than the familiar ones. Thus, perinatal undernutrition appears to interfere with the foundation of the olfactory development causing long-term olfactory discrimination deficits as revealed by the increased frequency and duration of visits to the source of odors that may be relevant for social behavior.

关键词： Olfactory Discrimination Main Olfactory System Perinatal Undernutrition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Neonatal Undernutrition on Development of the Dorsolateral Prefrontal Cortex Pyramidal Cells in the Rat

引用

Journal of Behavioral and Brain Science 2014年第1期4卷 49-57页

作者： Carmen Torrero Mirelta Regalado Lorena Rubio Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology National Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico

The dorsolateral prefrontal cortex (dlPFC) of the rat plays a role in the encoding of neuronal signals involved in conflict-induced behavioral adjustment, working memory, planning and executive abilities, attentional control and other cognitive responses. In altricial species, early perinatal undernutrition interferes with the morphofunctional organization of a number of central nervous system (CNS) structures including the prefrontal cortex. The effects of neonatal undernutrition on dendritic arbor density, perikaryon measurements, and the number of spines (detected by rapid-Golgi) of basilar dendritic segments in layer III pyramidal neurons of the dlPFC were examined in male Wistar rats on postnatal (PDs) 12, 20, and 30. In the underfed (U) subjects the distal portions of the dendritic arbors had a consistent hipoplasia, mainly on PD 30, with reduced cross sectional area, perimeter, and spine densities on the basilar dendrites on all days studied. Thus, the alterations of the dlPFC pyramidal neurons may interfere with the plastic synaptic activity and cognitive performance of rats subjected to the stress of early underfeeding. Characterizing these anatomical alterations may help to understand the disrupted cognitive processes associated with neonatal undernutrition.

关键词： Neonatal Undernutrition Prefrontal Cortex Development Stressed Rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：