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Protein hydrolysates in animal nutrition：Industrial production, bioactive peptides,and functional significance

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Journal of animal Science and Biotechnology 2017年第3期8卷 513-525页

作者： Yongqing Hou Zhenlong Wu Zhaolai Dai Genhu Wang Guoyao Wu Hubei Key Laboratory of animal nutrition and Feed Science Hubei Collaborative innovation Center for Animal Nutrition and Feed Safety Wuhan Polytechnic University Wuhan 430023 China College of animal Science and Technology China Agricultural University Beijing China Research and Development Division Shanghai Gentech Industries Group Shanghai China 201015 Department of animal Science Texas A&M University College Station. TX. USA 77843

Recent years have witnessed growing interest in the role of peptides in animal nutrition. Chemical, enzymatic, or microbial hydrolysis of proteins in animal by-products or plant-source feedstuffs before feeding is an attractive means of generating high-quality small or large peptides that have both nutritional and physiological or regulatory functions in livestock, poultry and fish. These peptides may also be formed from ingested proteins in the gastrointestinal tract, but the types of resultant peptides can vary greatly with the physiological conditions of the animals and the composition of the diets. In the small intestine, large peptides are hydrolyzed to small peptides,which are absorbed into enterocytes faster than free amino acids（AAs） to provide a more balanced pattern of AAs in the blood circulation. Some peptides of plant or animal sources also have antimicrobial, antioxidant,antihypertensive, and immunomodulatory activities. Those peptides which confer biological functions beyond their nutritional value are called bioactive peptides. They are usually 2–20 AA residues in length but may consist of 〉20AA residues. Inclusion of some（e.g. 2–8%） animal-protein hydrolysates（e.g., porcine intestine, porcine mucosa,salmon viscera, or poultry tissue hydrolysates） or soybean protein hydrolysates in practical corn-and soybean mealbased diets can ensure desirable rates of growth performance and feed efficiency in weanling pigs, young calves,post-hatching poultry, and fish. Thus, protein hydrolysates hold promise in optimizing the nutrition of domestic and companion animals, as well as their health（particularly gut health） and well-being.

关键词： animals nutrition Peptides Protein hydrolysates Sustainability

Corrigendum to“Point-of-care testing for lysine concentration in swine serum via blue-emissive carbon dots entrapped microfluidic chip”[animal nutrition 12(2023)236e244]

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animal nutrition 2023年第2期13卷 435-438页

作者： Chizhu Ding Xiang Chen Xiaoyu Chen Yue Liu Menglin Xia Ziyi He Qinshu Kang Xianghua Yan State Key Laboratory of Agricultural Microbiology Hubei Hongshan LaboratoryFrontiers Science Center for Animal Breeding and Sustainable ProductionCollege of ScienceCollege of Animal Sciences and TechnologyCollege of Veterinary MedicineHuazhong Agricultural UniversityWuhan430070China

Section 2.1:animal ethics approval number:HZAUSW-2002e0009 Change to:HZAUSW-2022e0011 Section 2.6:…200 mL solution of N-CDs(0.1 mg/mL)…Change to:…200 mL solution of N-CDs(1.5 mg/mL)…Section 3.1:…with the size ran... 详细信息

关键词： animal Cor testing

Direct-fed microbial: animal nutrition and reproduction responses

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Journal of Integrative Agriculture 2015年第3期14卷 494-496页

作者： Abdelfattah Z M Salem Nicolas Di Lorenzo Member of JIA Editorial Board Faculty of Veterinary Medicine and animal Science Autonomous University of the State of Mexico North Florida Research and Education Center University of Florida Marianna Guest Editor Dr.

Manipulating the gastrointestinal microbial ecosystem to enhance animal performance and reproductive responses has been one of the main goals of animal science researchers and *** restrictions to the use of antimicrobials as growth promoters led researchers to seek alternative practices that can show promise both from the standpoint of efficacy as well as from the practical and economic *** of the alternatives that surfaced as very promising in the last few decades is the use of direct-fed microbials （DFM） as a means to modulate the effects of the gastrointestinal microbiome on the host immune status, health and productivity.

关键词： microbial nutrition reproduction goals promise ecosystem fermentation anaerobic digestion pleased

Red osier dogwood and its use in animal nutrition:A review

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animal nutrition 2023年第2期13卷 64-77页

作者： Taiwo Joseph Erinle Martine Boulianne Younes Miar Robert Scales Deborah Adewole Department of animal Science and Aquaculture Faculty of AgricultureDalhousie UniversityTruro NSB2N 5E3Canada Department of Clinical Sciences Faculty of Veterinary MedicineUniversity of Montreal3200 Sicotte StreetSaint-Hyacinthe QCJ2S 2M2Canada Red Dog Enterprises Ltd. Swan River MBR0L 1Z0Canada

As the human population increases globally,the food animal industry has not been spared from the monumental demand for edible animal products,particularly *** has necessitated the simulta-neous expansion of the productivity of the animal sector to meet the ever-growing human *** antibiotics have been used in food animal production with commendable positive impacts on their growth performance,their sole contributive factor to the increasing incidence of antimicrobial resistance has ushered the strict restrictions placed on their use in the animal *** has handed a setback to both animals and farmers;thus,the intense push for a more sustainable antibiotic alternative for use in animal *** use of plants with concentrated phytogenic compounds has gained much interest due to their beneficial bioactivities,including antioxidant and selective *** the reported beneficial activities of phytogenic additives on animals vary due to their varying total polyphenol concentrations(TPC),red osier dogwood(ROD)plant materials boast of high TPC with excellent antioxidant prowess and growth improvement capacities compared to some plant extracts commonly used in ***,its adoption in research and commercial scale is still ***,the present review aims to provide concise information on the dietary potential of ROD plant materials in animal feeding.

关键词： Red osier dogwood Antibiotic-alternative Polyphenolic compounds Antioxidant Antimicrobial

Corrigendum to “Functionality of a next generation biosynthetic bacterial 6-phytase in enhancing phosphorus availability to weaned piglets fed a corn-soybean meal-based diet without added inorganic phosphate” [animal nutrition 6/1 (2020) 24e30]

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animal nutrition 2021年第4期7卷 1388-1388页

作者： Yueming Dersjant-Li Boris Villca Vincent Sewalt Arno de Kreij Leon Marchal Deepak E.Velayudhan Robin *** Trine Christensen Rie Mejldal Igor Nikolaev Sina Pricelius Hye-Sook Kim Svend Haaning Jens F.Sørensen Rosil Lizardo DuPont nutrition and Biosciences Archimedesweg302333CN Leidenthe Netherlands Institut de Recerca I Tecnologia Agroaliment_aries Centre Mas de BoverCtra.Reus-El Morell km.3.8E-43120ConstantiSpain DuPont nutrition&Biosciences 925 Page Mill RoadPalo AltoCA 94304USA DuPont nutrition&Biosciences 21 Biopolis RoadNucleosSouth Tower138567Singapore DuPont nutrition and Biosciences Edwin Rahrs Vej 38DK-8220BrabrandDenmark

The authors regret that the following errors are found in the Materials and method under section *** *** following sentence:“Analysis of exogenous phytase activity in feeds was performed according to Engelen et al.(1994)”should instead to be corrected to:“Analysis of exogenous phytase activity in feeds was performed according to a modified version of the 2000.12 AOAC method(Engelen et al.,2001).”

关键词： analysis. soybean inorganic

Impacts of prenatal nutrition on animal production and performance： a focus on growth and metabolic and endocrine function in sheep

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Journal of animal Science and Biotechnology 2018年第1期9卷 10-23页

作者： Prabhat Khanal Mette Olaf Nielsen Department of Veterinary and animal Sciences Faculty of Health and Medical SciencesUniversity of Copenhagen Gronnegardsvey 31st floorDK-1870 Frederiksberg CDenmark Department of nutrition Faculty of MedicineTransgenic Animal and Lipid StorageNorwegian Transgenic Centre(NTS)University of OsloOsloNotway

The concept of foetal programming（FP） originated from human epidemiological studies, where foetal life nutrition was linked to health and disease status later in life. Since the proposal of this phenomenon, it has been evaluated in various animal models to gain further insights into the mechanisms underlying the foetal origins of health and disease in humans. In FP research, the sheep has been quite extensively used as a model for humans. In this paper we will review findings mainly from our Copenhagen sheep model, on the implications of late gestation malnutrition for growth, development, and metabolic and endocrine functions later in life, and discuss how these implications may depend on the diet fed to the animal in early postnatal life. Our results have indicated that negative implications of foetal malnutrition, both as a result of overnutrition and, particularly, late gestation undernutrition, can impair a wide range of endocrine functions regulating growth and presumably also reproductive traits. These implications are not readily observable early in postnatal life, but are increasingly manifested as the animal approaches adulthood. No intervention or cure is known that can reverse this programming in postnatal life. Our findings suggest that close to normal growth and slaughter results can be obtained at least until puberty in animals which have undergone adverse programming in foetal life, but manifestation of programming effects becomes increasingly evident in adult *** to the risk of transfer of the adverse programming effects to future generations, it is therefore recommended that animals that are suspected to have undergone adverse FP are not used for reproduction. Unfortunately, no reliable biomarkers have as yet been identified that allow accurate identification of adversely programmed offspring at birth,except for very low or high birth weights, and, in pigs, characteristic changes in head shape（dolphin head）. Future efforts should be therefo

关键词： Adipose tissue Endocrine function Foetal programming Metabolic function Sheep

The toxicological effect of dietary excess of saccharicterpenin,the extract of camellia seed meal,in piglets

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Journal of Integrative Agriculture 2020年第1期19卷 211-224页

作者： WANG Man YU Bing HE Jun YU Jie LUO Yu-heng LUO Jun-qiu MAO Xiang-bin CHEN Dai-wen Key Laboratory of animal Disease-Resistance nutrition Animal Nutrition InstituteSichuan Agricultural University

Recently, saccharicterpenin extracted from Camellia oleifera seed meal has become a widely used feed supplement in animal husbandry. In order to assess its safety, this study was designed to investigate the toxicity and histopathological effects of saccharicterpenin on piglets. One hundred-fifty weaned pigs((Yorkshire×Landrace)×Duroc), 75 males and 75 females with body weight(BW) of(7.35±0.29) kg, were randomly allotted to groups receiving diets supplemented with 0, 500, 1 000, 2 500 or 5 000 mg kg^–1 saccharicterpenin for 70 d. The diet with 500 mg kg^–1 saccharicterpenin supplementation improved liver glutathione peroxidase(GSH-Px) activity, and the diet with 1 000 mg kg^–1 saccharicterpenin supplementation improved liver glutathione S-transferase(GSH-S) activity in piglets on d 70(P<0.05). At 2 500 mg kg^–1, saccharicterpenin in the diets reduced average daily feed intake(ADFI) and average daily gain(ADG) of piglets from d 1 to 35, damaged the cardiac tissue and liver on d 35, and decreased white blood cell counts(WBC), activities of catalase(CAT) and GSH-Px, and concentrations of glucose(GLU) and urea nitrogen(BUN) in the blood of piglets on d 70(P<0.05). In addition, diets with 5 000 mg kg^–1 saccharicterpenin supplementation reduced ADFI, ADG and increased diarrhea rates of piglets from d 36 to 70, and decreased hemoglobin(HGB) concentration and activity of CAT in the blood of piglets on d 70(P<0.05). Moreover, at a rate of 5 000 mg kg^–1, saccharicterpenin supplementation increased pancreas index on d 35 and hepatic index on d 70, and damaged cardiac tissue, liver and spleen during the whole experimental period(P<0.05). These results suggested that dietary 500 mg kg^–1 saccharicterpenin supplementation had beneficial effects on piglets, but excessive supplementation(2 500 or 5 000 mg kg^–1) of saccharicterpenin in the diets could lead to growth retardation, hematological abnormalities and organ injuries.

关键词： growth retardation hematology organ injury piglets saccharicterpenin

The effect of dietary tryptophan levels on oxidative stress of liver induced by diquat in weaned piglets

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Journal of animal Science and Biotechnology 2015年第1期6卷 104-110页

作者： Xiangbing Mao Mei Lv Bing Yu Jun He Ping Zheng Jie Yu Quyuan Wang Daiwen Chen animal nutrition Institute Sichuan Agricultural University Key Laboratory of animal Disease-Resistance nutrition Ministry of Education

Oxidative stress can induce abnormal tryptophan metabolism. The present study was mainly conducted to determine the effect of dietary tryptophan levels on oxidative stress in the liver of weaned pigs challenged by diquat. A total of 36 PIC piglets weaned at 21 days of age were randomly allotted to 1 of 3 diets containing dietary tryptophan levels of 0.18, 0.30, and 0A5% for 14 d. On day 8, the piglets were injected intraperitoneally with sterile 0.9% NaCI solution or diquat （10 mg/kg body weight）. During the first 7 d of trial, increasing dietary tryptophan levels enhanced average daily gain （P = 0.09） and average daily feed intake （P = 0.08）, and decreased the feed efficiency （P 〈 0.05） of piglets. The growth performance was decreased by diquat injection （P 〈 0.05）. Diquat injection also decreased the activities of the superoxide dismutase （SOD） and glutathione peroxidase （GPx） in the plasma and liver （P 〈 0.05）, increased plasma malondialdehyde （MDA）（P 〈 0.05） and urea nitrogen （P 〈 0.05） concentrations, and enhanced MDA concentration （P = 0.09） and tryptophan 2,3-dioxygenase （TDO） activity （P = 0.07） in liver of piglets. Increasing dietary tryptophan levels could attenuate the effects of diquat injection on the MDA （P = 0.06） concentration and the activities of SOD （P = 0.09） and GPx （P = 0.05） of the liver, and plasma urea nitrogen （P = 0.06） concentration in the piglet. There was a synergistic role for increasing TDO activity in the liver between dietary tryptophan levels and diquat injection （P 〈 0.05）. These results suggest that increasing dietary tryptophan levels could attenuate the oxidative stress of the liver in weaned piglets intraperitoneally injected with diquat via enhancing the antioxidant capacity.

关键词： Antioxidant capacity Diquat Oxidative stress of livers Tryptophan,Weaned piglets

Effect of dietary supplementation with mulberry(Morus alba L.) leaves on the growth performance,meat quality and antioxidative capacity of finishing pigs

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Journal of Integrative Agriculture 2019年第1期18卷 143-151页

作者： ZENG Zhu JIANG Jun-jie YU Jie MAO Xiang-bing YU Bing CHEN Dai-wen Key Laboratory for animal Disease-Resistant nutrition Ministry of Education/Institute of Animal NutritionSichuan Agricultural University

The present study was conducted to evaluate the effect of dietary mulberry(Morus alba L.) leaves powder(MLP) supplementation on meat quality of finishing pigs.A total of 40 Duroc×Landrace×Yorkshire pigs(initial body weight of(40.5±0.63) kg) were randomly allotted into two treatments,fed either with control diet or 15% MLP diet for 85 *** results showed that MLP diet decreased(P≤0.05) average daily gain(ADG) and increased(P<0.05) feed/gain ratio(F/G) in the finishing and whole *** diet also decreased(P<0.05) carcass weight,dressing percentage,last rib and average backfat ***,MLP diet increased(P<0.05) intramuscular fat(IMF) content,decreased(P<0.05) shear force,cooking loss and drip *** addition,MLP diet increased(P<0.05) total antioxidative capacity,glutathione peroxidase and tended(P<0.10) to increase total superoxide dismutase in *** longissimus thoracis,myosin heavy chain(MyHC) I and IIa mRNA levels were increased(P≤0.05) for MLP *** conclusion,15% MLP supplementation reduced the growth performance and carcass traits,but improved meat quality of finishing pigs possibly through the change of myofiber characteristics,enhancement of antioxidative capacity and increase of IMF.

关键词： mulberry leaves powder meat quality myofibers antioxidation pigs