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Predicting suitable habitat of an invasive weed Parthenium hysterophorus under future climate scenarios in Chitwan Annapurna Landscape,Nepal

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Journal of Mountain Science 2019年第10期16卷 2243-2256页

作者： MAHARJAN Seerjana SHRESTHA Bharat Babu JOSHI Mohan Dev DEVKOTA Anjana MUNIAPPAN Rangaswamy ADIGA Abhijin JHA Pramod Kumar Central Department of Botany Tribhuvan UniversityKirtipurKathmanduNepal Department of Plant Resources ThapathaliKathmanduNepal IPM Innovation Lab Virginia Tech526Prices Fork RoadBlacksburgVA24061USA Biocomplexity Institute and Initiative University of VirginiaUSA

Chitwan-Annapuma Landscape(CHAL)in central Nepal is known for its rich biodiversity and the landscape is expected to provide corridors for species range shift in response to climate *** assessments have identified biological invasions and other anthropogenic activities as major threats to the biodiversity in the *** of the rapidly spreading Invasive Alien Plant species(IAPs)in the CHAL is Parthenium hysterophorus L.,a neotropical invasive weed of global *** study aimed to investigate the current and future projected suitable habitat of *** in the CHAL using MaxEnt modelling in three'Representative Concentration Pathways'(RCPs 2.6,4.5 and 8.5)corresponding to different greenhouse gases emissiontrajectories for the year 2050 and 2070.A total of 288species occurrence points,six bioclimatic variablesmean diurnal range,isothermality,annual precipitation,precipitation of driest month,precipitation seasonality,precipitation of driest quarter and two topographic variables(aspect and slope)were selected for MaxEnt *** range shift in terms of increase or decline in the suitable habitat areas under the projected scenarios were *** and annual precipitation were the most important variables that explained the current distribution of *** percent of the total area of CHAL was predicted to be suitable habitat for the growth of *** in the current climatic *** gain in the suitable habitat of this noxious weed was found under RCP 4.5 scenario in 2050 and *** there will be a loss in thesuitable habitat under RCP 8.5 scenario in 2050 *** of four physiographic regions present in CHAL,three regions-Siwalik,Middle Mountain and High Mountain have suitable habitat for *** under current climatic *** mountainous region is likely to be affected more than the Siwalik region by further spread of *** in the future under low(R

关键词： Parthenium weed Ecological Niche Model MaxEnt Invasive species Habitat suitability

Effect of cholesterol metabolism on hepatolithiasis

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World Journal of Gastroenterology 2025年第1期31卷 157-162页

作者： Lin Zheng Zi-Yu Ye Jun-Ji Ma Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesNo.215 Heping West RoadShijiazhuang 050000Hebei ProvinceChina

Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after *** metabolism seems to play an important role in hepatoli-thiasis pathogenesis.A high cholesterol diet is one of the significant reasons for the increasing incidence of ***,regular diet and appropriate medical intervention are crucial measures to prevent hepatolithiasis and reduce recurrence rate after *** dietary cholesterol and drugs that increase cholesterol stone solubility are key therapeutic approaches in treating *** article discusses the cholesterol metabolic pathways related to the pathogenesis of hepatolithiasis,as well as food intake and targeted therapeutic drugs.

关键词： Hepatolithiasis Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct

Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui Liu Chao Fang Qiuxia Peng Wen Qin Xuebing Yan Kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

Metal separations of interest to the Chinese metallurgical industry

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Journal of Rare Earths 2010年第S1期28卷 22-29页

作者： S.R.Izatt N.E.Izatt R.L.Bruening IBC Advanced Technologies Inc.856 E.Utah Valley DriveAmerican ForkUT 84003U.S.A.

IBC Advanced Technologies’ Molecular Recognition Technology(MRT) SuperLig products selectively and rapidly bind with target species enabling their selective removal from *** MRT process can produce a high purity separation product of maximum added value at a competitive *** products have high selectivity for many target species which can include metal ions,anions,and neutral *** operation,the SuperLig product is first placed in a packed column.A solution containing a mixture of the target species and other chemical species is then passed through the *** target species is removed selectively by the SuperLig product,the column is washed to remove residual feed solution,and the target species is recovered by a minimal quantity of *** result is a pure and concentrated species that can be kept for its value or disposed of *** process is environmentally and ecologically friendly with no organic solvents being *** paper provides a review of some examples of applications of MRT to separations of interest to the Chinese metallurgical *** are several applications of MRT,including Pd separations from Pt metal refinery streams and low-grade spent catalyst wastes,Rh recovery from spent auto catalyst and other feeds,Re removal from selected impurity ions,Cd removal from Co electrolyte,Bi removal from Cu electrolyte,In and Ge separations from difficult matrices,and removal of bivalent first transition series and other metal ions from acid mine drainage(Berkeley Pit,Montana).Finally,the potential application of MRT to separations involving the recovery of rare earth metals and Li from low-level waste solutions and end-of-life products is discussed.

关键词： selective and environmentally friendly metal separations molecular recognition technology SuperLig platinum group metals minor metals transition series metals rhenium cadmium indium germanium bismuth rare earth metals lithium

Evaluating Room Acoustics for Speech Intelligibility

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Open Journal of Applied Sciences 2019年第7期9卷 601-612页

作者： Caitlin R. Kunchur Dutch fork High School Irmo SC USA

Room acoustics play an important role in the intelligibility of speech. The main aspect of acoustics that is usually studied is the duration of the reverberation decay, since a long decay causes a blurring of phonemes. However, other parameters of the acoustics such as the strength of the reverberation can actually improve intelligibility. These factors do not receive the same attention. In many common practical situations such as classrooms and residential rooms, it would be of value to quantitatively study the acoustics to optimize the room’s function, but this is not done routinely due to the expected expense or difficulty involved. This research explores inexpensive first-principle methods to quantitatively measure three key parameters of a room’s acoustics: the reverberation decay time RT60, the reverberant intensity IR, and the room’s total absorption A. The required equipment includes two laptops installed with certain free softwares. Generation of the required noise signal and level detection are carried out using the REW software, and long-duration recordings are carried out using the Audacity software. The procedures are simple enough to be performed without specialized training and do not require specialized equipment, only commonly available household resources. This research also sheds light on the fact that not all reverberation is bad and that strong but short-duration reverberation can enhance communication. This information can be expected to benefit schools and other venues where speech intelligibility is vital.

关键词： Acoustics Reverberation Speech Music Communication

Quantitative Measurement of the Exposure Response of Digital Cameras

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Journal of Analytical Sciences, Methods and Instrumentation 2019年第3期9卷 43-50页

作者： Caitlin R. Kunchur Dutch fork High School Irmo SC USA

Digital cameras span a large range in price and performance. Consumers often focus mainly on the resolution in pixels when shopping for a camera. Of equal importance is the quality of the optics and the exposure response. Digital cameras generally have a linear exposure response, but the amount of noise and the dynamic range vary. It is difficult to obtain quantitative information on these parameters to make an informed assessment. This work explores and demonstrates first-principles methods to measure the exposure response to make meaningful comparisons between different camera models. It also shows how to make the most of a particular camera by measuring its noise level and dynamic range, to understand the limits of its useable ISO amplification. The methods only require a computer and free software to download images and extract their RGB pixel values. The analysis, based on the RGB values, uses standard spreadsheet software. The procedures are therefore accessible to anyone with a digital camera and computer, and will help to reduce speculation in comparing cameras, and help consumers make an informed decision.

关键词： Photography Image Imaging

Noni juice is not hepatotoxic

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World Journal of Gastroenterology 2006年第22期12卷 3616-3619页

作者： Brett J West C Jarakae Jensen Johannes Westendorf Research and Development Department Tahitian Noni International American ForkUtahUnited States University Medical School of Hamburg Department of Toxicology HamburgGennany

Noni juice （Morinda citrifolia） has been approved for use as a safe food within the European Union, following a review of safety. Since approval, three cases of acute hepatitis in Austrian noni juice consumers have been published, where a causal link is suggested between the liver dysfunction and ingestion of anthraquinones from the plant. Measurements of liver function in a human clinical safety study of TAHITIAN NONI Juice, as well as subacute and subchronic animal toxicity tests revealed no evidence of adverse liver effects at doses many times higher than those reported in the case studies. Additionally, M. citrifolia anthraquinones occur in the fruit in quantities too small to be of any toxicological significance. Further, these do not have chemical structures capable of being reduced to reactive anthrone radicals, which were implicated in previous cases of herbal hepototoxicity. The available data reveals no evidence of liver toxicity.

关键词： Noni juice Morinda citrifolia Novel food Human clinical safety study

Cold metal transfer(CMT) technology-An overview

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Defence Technology（防务技术） 2018年第1期14卷 28-44页

作者： S.Selvi A.Vishvaksenan E.Rajasekar Mechanical Engineering Institute of Road and Transport Technology Automobile Engineering Institute of Road and Transport Technology

Cold Metal Transfer technology has revolutionized the welding of dissimilar metals and thicker materials by producing improved weld bead aesthetics with controlled metal deposition and low heat-input. In this study, the process, weld combinations, laser-CMT hybrid welding and applications of CMT welding are critically reviewed. Microstructure and other weld characteristics have been discussed at length for various base metal combinations. Particularly, the welding of aluminium and steel with better results has been possible with CMT Welding. The results reviewed in this article indicate that the CMT-Laser hybrid welding is more preferable to Laser or Laser hybrid welding. CMT welding has found applications in automobile industries, defence sectors and power plants as a method of additive manufacturing.

关键词： Cold metal transfer [CMT]Welding Laser-CMT welding Additive manufacturing Composite joint Metal inert gas[MIG] Metal active gas[MAG]

The good and evil of complement activation in HIV-1 infection

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Cellular & Molecular Immunology 2010年第5期7卷 334-340页

作者： Qigui Yu Richard Yu Xuebin Qin Department of Microbiology and Immunology University School of Medicine635 Barnhill DriveIndianapolisINUSA Harvard Medical School Laboratory for Translational ResearchCambridgeMAUSA

The complement system,a key component of innate immunity,is a first-line defender against foreign pathogens such as *** role of the complement system in HIV-1 pathogenesis appears to be *** the complement system plays critical roles in clearing and neutralizing HIV-1 virions,it also represents a critical factor for the spread and maintenance of the virus in the infected *** addition,complement regulators such as human CD59 present in the envelope of HIV-1 prevent complement-mediated lysis of *** novel approaches are proposed to combat HIV-1 infection through the enhancement of antibody-dependent complement activity against *** this paper,we will review these diverse roles of complement in HIV-1 infection.

关键词： antibody complement HIV-1 human CD59