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Breast cancer awareness in reproductive women in the low-and middle-income countries:a scoping review

Frontiers of Nursing 2024年第2期11卷 139-151页

作者： Made Satya Nugraha Gautama Saranya Pimolkatekul Nguyen Ngoc Nhat Thanh Department of Nursing Faculty of MedicineUniversitas Pendidikan GaneshaBali 81116Indonesia School of Nursing College of NursingTaipei Medical UniversityTaipeiTaiwan 110China Global Health and Development Program College of Public HealthTaipei Medical UniversityTaipeiTaiwan 110China

Objective:This study aimed to assess breast cancer(BC)awareness among reproductive women in low-and middle-income countries(LMICs),identify influencing factors,and propose feasible interventions or programs.Methods:We followed a 5-step process using a modified version of Arksey and O’Malley framework methodology.A comprehensive search was conducted on the Embase,PubMed,and CINAHL electronic databases for literature published within 10 years(from 2012 to 2022).Results:Thirty-three papers published between 2012 and 2020,spanning 18 countries,were included.Of these,45.6%described a good level of knowledge,while 24.2%reported that women at reproductive ages had good awareness.Twelve influencing factors were identified in 3 categories:socio-demographic(family history,personal history,marital status,age,religion,income status,living place,and occupation),personal(self-efficacy,education,and perceived level),and external(advertisements promoting awareness).Educational programs were recommended in most(>72%)of the included studies.Conclusions:While most studies reported high levels of knowledge and awareness,some found low prevalence among certain groups.Factors affecting knowledge and awareness were classified into socio-demographic,personal,and external categories,with socio-demographic factors such as age,education,income,and marital status being the most frequently cited.The studies recommended implementing educational programs,health prevention strategies,and social interventions to increase BC knowledge and awareness.

关键词： awareness breast cancer low-and middle-income countries reproductive women scoping review

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Effect of Acupuncture on Outcomes of in vitro Fertilisation:A scoping review

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Chinese Journal of Integrative Medicine 2022年第5期28卷 472-480页

作者： XIU Wen-cui GANG Wei-juan JIAO Rui-min SHI Lan-jun YANG Ji-wei JING Xiang-hong SHI Xiao-shuang Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing(100700)China

Objectives:To identify,examine and summarize the available evidence on the effectiveness and safety of acupuncture for in vitro fertilisation(IVF)outcomes.Methods:Eight electronic databases,including Pub Med,EMBASE,Cochrane Database of Systematic review,Cochrane Central Register of Controlled Trials,China National Knowledge Infrastructure,Wanfang Database,Chinese Biomedical Database and VIP Database,were searched,supplemented by manual searches.Two researchers independently conducted the literature screening,data extraction,and methodological quality assessments.A narrative description was provided to show the general information and specific characteristics of the included studies.A bubble plot was used to visually display the overall effects of acupuncture on IVF outcomes.Results:Eighty-two studies were identified,including 64 primary studies and 18 systematic reviews.Transcutaneous electrical acupoint stimulation,electric acupuncture and manual acupuncture were applied in most studies and compared with no acupuncture,sham acupuncture and placebo acupuncture control groups.Sixty-three(98.4%)primary studies reported clinical pregnancy rate,and positive effects of acupuncture were found in 34 studies(54.0%).Live birth rate was reported in only 18(28.1%)primary studies,of which 10(55.6%)showed positive results.In addition,only 8 and 2 systematic reviews showed that acupuncture could increase clinical pregnancy events and live birth events,respectively.However,none of these reviews was of high methodological quality.Conclusions:Available evidence suggests that acupuncture therapy could improve clinical pregnancy rates.However,whether acupuncture could increase live birth events was difficult to determine based on the few studies that have reported this outcome indicator.Furthermore,the methodological quality of most systematic reviews was assessed as critically low or low.Studies with a rigorous design and standardized implementation should be performed to refine the available evidence.

关键词： acupuncture in vitro fertilisation clinical pregnancy rate live birth rate scoping review

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Vitamin E in the management of pancreatic cancer: A scoping review

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World Journal of Gastrointestinal Oncology 2023年第6期15卷 943-958页

作者： Sophia Ogechi Ekeuku Effiong Paul Etim Kok-Lun Pang Kok-Yong Chin Chun-Wai Mai Department of Pharmacology Faculty of MedicineUniversiti Kebangsaan MalaysiaKuala Lumpur 56000Malaysia Faculty of Applied Sciences UCSI UniversityKuala Lumpur 56000Malaysia Newcastle University Medicine Malaysia Iskandar Puteri 79200JohorMalaysia State Key Laboratory of Oncogenes and Related Genes Renji-Med X Clinical Stem Cell Research CenterRen Ji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of Pharmaceutical Chemistry Faculty of Pharmaceutical SciencesUCSI UniversityKuala Lumpur 56000Malaysia

Pancreatic cancer is the leading cause of cancer mortality worldwide.Research investigating effective management strategies for pancreatic cancer is ongoing.Vitamin E,consisting of both tocopherol and tocotrienol,has demonstrated debatable effects on pancreatic cancer cells.Therefore,this scoping review aims to summarize the effects of vitamin E on pancreatic cancer.In October 2022,a literature search was conducted using PubMed and Scopus since their inception.Original studies on the effects of vitamin E on pancreatic cancer,including cell cultures,animal models and human clinical trials,were considered for this review.The literature search found 75 articles on this topic,but only 24 articles met the inclusion criteria.The available evidence showed that vitamin E modulated proliferation,cell death,angiogenesis,metastasis and inflammation in pancreatic cancer cells.However,the safety and bioavailability concerns remain to be answered with more extensive preclinical and clinical studies.More in-depth analysis is necessary to investigate further the role of vitamin E in the management of pancreatic cancers.

关键词： Anti-cancer treatment Pancreatic cancer scoping review Tocopherol Tocotrienol Vitamin E

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Vestibular migraine in low-and lower-middle-income countries:A scoping review

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Journal of Otology 2023年第3期18卷 173-184页

作者： Eric K.Kim Amina Seguya May Htoo Thaw Peggy Tahir Eric J.Formeister Christopher J.Waterworth Ali F.Jaffer The Global Otolaryngology-Head and Neck Surgery Initiative USA Department of Otolaryngology-Head and Neck Surgery University of CaliforniaSan FranciscoSan FranciscoCAUSA Ear Nose and Throat SurgeonMulago National Referral HospitalKampalaUganda Eye ORL-HNS HospitalMandalayMyanmar UCSF Library University of CaliforniaSan FranciscoCAUSA Department of Otolaryngology-Head and Neck Surgery Duke UniversityDurhamNCUSA Department of Audiology and Speech Pathology The University of MelbourneVictoriaAustralia Nossal Institute for Global Health University of MelbourneVictoriaAustralia HearWell Audiology Clinic Dar es SalaamTanzania

Background:Vestibular migraine(VM)is a common cause of dizziness that is underrecognized,underdiagnosed,and challenging to effectively treat.The prevalence,appropriate diagnostic workup,and therapies for VM in low-and lower-middle-income countries(LLMICs)remain understudied.The objective of this scoping review is to evaluate the current state of VM research in LLMICs.Methods:PubMed,Embase,and Web of Science databases were searched to execute a scoping review of VM.Keywords“vestibular diseases”and“vertigo”were used in combination with terms referring to LLMICs as defined by the World Bank.Title and abstract screening,full-text review,and data collection were conducted by two authors independently.Results:Twenty-six studies were included in the scoping review.Most studies were cross-sectional(57.7%)or case studies/series(23.1%)and were conducted in urban settings only(92.3%).Geographic distribution of studies was skewed,with 65.4%of articles originating from India.The prevalence of VM among clinic patients ranged from 0.3%to 33.3%.VM most frequently presented as headache,nausea and vomiting,and photophobia.Radiographic imaging,audiometry,and electronystagmography/videonystagmography were the three most commonly utilized diagnostic modalities in the dizziness workup.The most studied pharmacotherapies included calcium channel blockers,followed by beta-blockers and antiepileptics.Case studies and series discussed less common VM pharmacotherapies,such as ayurvedic medicine.Conclusions:There is a need for more VM research in LLMICs,including innovative diagnostic approaches and therapies that can improve VM care globally.Equitable partnerships between LLMIC and highincome country researchers must expand vestibular research capacity and productivity in LLMICs.

关键词： Vestibular migraine Migraine Global Otolaryngology scoping review

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The Influence of Fat Mass and Obesity-Associated(FTO)Gene on the Effect of Physical Activity(PA)on Risk of Obesity:scoping review

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Journal of Science in Sport and Exercise 2023年第3期5卷 193-202页

作者： Hamad I.Alrajhi Anwar B.Almutairi Hesham N.Alrowayeh Physiology Department Faculty of MedicineKuwait UniversityP.O.Box 596913060 SafatKuwait Physical Therapy Department Faculty of Allied HealthKuwait UniversityKuwaitKuwait

Purpose We aimed to conduct a scoping review by reviewing studies that investigated the influence of the fat mass and obesity-associated(FTO)gene on the effect of physical activity(PA)on risk of obesity.The research questions of this review were:(1)“What is known from existing literature about the influence of the FTO gene on the effect of physical activity on obesity?”(2)“What are the gaps in existing literature in that area?”Methods Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for scoping reviews(PRISMA-ScR)Checklist and the five-stage methodological framework outlined by Arksey and O’Malley were utilized to conduct this scoping review.Four online databases were searched for articles between July 2021 and August 2021.The articles were chosen to be included if they were:published in English;included male and/or female adult participants(ages 18-65);looked at the effect of FTO on overweight/obesity;and included PA/exercise/physical fitness intervention or examination.Excluded studies were studies with a population that had a diagnosis of any disorder or condition other than obesity.Results Nine articles were selected for this scoping review,one of which is a conference abstract.Based on the type,the articles were categorized into intervention(n=3),observational(n=5),and review article(n=1).All articles were sum-marized in terms of questions and main findings.Conclusion This scoping review presented evidence that the FTO gene could influence the effect of PA on obesity.The gaps in knowledge were evident in the limited number of intervention studies.

关键词： FTO Physical activity Exercise scoping review

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Moxibustion for COVID-19:a systematic scoping review

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Acupuncture and Herbal Medicine 2022年第3期2卷 162-171页

作者： Meng Xia Bo Pang Shaowei Yi Xinjue Shan Shizhe Deng Yinan Qin Tao Jiang Hai Lu Alberta College of Acupuncture&Traditional Chinese Medicine AlbertaCanada Evidence-based Medicine Center Tianjin University of Traditional Chinese MedicineTianjinChina School of Acupuncture-moxibustion and Tuina Tianjin University of Traditional Chinese MedicineTianjinChina School of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina Department of Acupuncture and Moxibustion First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina School of Acupuncture-moxibustion and Tuina Shaanxi University of Chinese MedicineXianyangChina Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical SchoolNanjingChina

Objective:Moxibustion has been widely used in the prevention and treatment of COVID-19.However,there is no systematic review of current topics and clinical findings on moxibustion for COVID-19.We conducted this scoping review to systematically summarize and analyze the themes and findings of published articles,and to provide an overview of current knowledge and practice of moxibustion for COVID-19.Methods:PubMed,Embase,Cochrane Library,Web of Science,China National Knowledge Infrastructure,SinoMed,Wan Fang Data,and VIP databases were searched from inception until April 2022.The relevant data were presented through bar graphs,structured tables,and figures along with descriptive statistics and analysis.This scoping review was conducted based on the PRISMA-ScR Checklist.Results:A total of 76 articles were reviewed:47 reviews,19 clinical research studies,seven systematic reviews(all were protocols),and three guidelines.All the studies were conducted by Chinese researchers and published from January 1,2020 to March 14,2022.The feasibility of moxibustion in the prevention and treatment of mild or moderate COVID-19 is based on the consensus of therapeutic mechanisms and effectiveness.The most adopted approach was the suspended and gentle moxibustion,and the most frequently applied or recommended acupoints were found to be ST36,CV8,CV6,CV4,CV12,GV14,BL13,LI4,ST25,and LR3.Conclusions:As a convenient and safe traditional Chinese medicine(TCM)therapy with its specific feature,moxibustion has been significantly effective at ameliorating mild or moderate symptoms among COVID-19 patients.Further large-scale,welldesigned research and international cooperation are still warranted in clinical evaluations of moxibustion.

关键词： COVID-19 Moxibustion scoping review

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Suicide in Digestive System Cancers: A scoping review

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International Journal of Mental Health Promotion 2023年第1期25卷 1-20页

作者： Jie Chen Xiaoping Ding Xin Peng Deying Hu Department of Nursing Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430000China School of Nursing Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430000China Cancer Center Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430000China

Digestive system cancers are important causes of morbidity and mortality worldwide.Cancer patients are more likely to commit suicide.The objective of this scoping review is to provide a comprehensive and updated summary of the existing literature on suicide among patients with digestive system cancers to identify the incidence and risk factors relevant to suicide in these populations.The PRISMA-Scr(Preferred Reporting Items for Systematic reviews and Meta-Analyses extension protocol for scoping reviews)protocol was used.The review was based on relevant articles published prior to January 2022 in databases of Web of Science and PubMed.The authors identified 21 records that met the criteria for inclusion.Among the 21 articles,18(n=85.7%)reported suicide risk factors,21(n=100%)evaluated the incidence of suicide and 16(n=76.2%)involved the variation in suicide rates.Only one study comprehensively reported that the suicide rate for this population was 32.8 per 100,000 years and the standardized mortality ratio(SMR)was 1.91.Most suicides occurred in patients with pancreatic,esophageal,and gastric cancers.The factors associated with suicide in digestive system cancers included male gender,older age,the white race,single status,advanced stage of disease,and cancer metastasis.The most critical time for suicide was in the early post-diagnostic period.It is indispensable to identify suicide in these cancer patients,especially those with high-risk factors.In the future,more prospective research may be needed to provide more reliable support and care to prevent suicide.

关键词： Digestive system cancer suicidal death suicidal ideation risk factor scoping review

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Traditional Chinese medicine for promoting mental health of patients with COVID-19:a scoping review

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Acupuncture and Herbal Medicine 2022年第3期2卷 184-195页

作者： Zhaochen Ji Haiyin Hu Danlei Wang Marco Di Nitto Alice Josephine Fauci Masayoshi Okada Kai Li Hui Wang Evidence-Based Medicine Center Tianjin University of Traditional Chinese MedicineTianjinChina Joint Sino-Italian Laboratory of Traditional Chinese Medicine Italian National Institute of HealthRomeItaly Department of Surgery Kobe University School of MedicineKobeJapan Shanxi Provincial Key Laboratory of classical prescription strengthening yang ShanxiChina

Objective:This study aimed to systematically review and depict the current studies of traditional Chinese medicine for the mental health of patients with coronavirus disease 2019(COVID-19).Methods:A scoping review was conducted by searching PubMed,Web of Science,CNKI,Wanfang database,VIP database,and SinoMed,with the retrieval time being from the establishment of the database to April 18,2022.The basic information of the included studies,objective,design,types of patients,interventions,outcomes,etc.,was reviewed and summarized narratively.Methodological quality was assessed using the Cochrane Risk of Bias assessment tool,the methodological index for nonrandomized studies or the Newcastle-Ottawa scale.Results:We identified 30 traditional Chinese medicine(TCM)studies from six databases.Among them,finished randomized controlled trials(n=16)accounted for most of the studies,followed by single-arm studies(n=9).In terms of study theme,20 studies defined the mental health of patients with COVID-19 as the research theme.Psychological assessment was included in the inclusion criteria(performed before participation)of nine studies,whereas the other studies only mentioned the mental outcomes.TCM interventions included TCM exercises(Yijinjing,Baduanjin,Liuzijue,Taichi),acupoint stimulation(auricular and body points),moxibustion,decoction,or granules based on TCM syndrome differentiation,decoction,or granules with fixed formulae(Baidu Jieduan granules,Xuanfei Baidu decoction,and Qingfei Paidu decoction),Chinese patent medicine(Jinhua Qinggan granules),TCM psychological therapy(TCM ideological therapy,TCM five-tone therapy,and TCM psychological sand table),and TCM nursing(dialectical care,dialectical diet,and psychological counseling).Anxiety and depression were the main outcomes evaluated in regard to mental health in patients with COVID-19.The limitations of methodological quality were predominantly from follow-up,blinding,and registration.Positive results were reported by 27 studies(90%,n=30).Conclusion:We summarized the ex

关键词： COVID-19 Mental health Psychological health scoping review Traditional Chinese medicine

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scoping review of cochlear implantation in Susac’s syndrome

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2021年第9期7卷 126-132页

作者： Philip L.Perez Andrew A.McCall Barry E.Hirsch Department of Otolaryngology University of PittsburghPittsburghPA15213USA

Objective:scoping review of published literature to establish clinical characteris tics and audiologic outcomes in patients diagnosed with Susac’s Syndrome(SS)who have undergone cochlear implantation(CI).Data sources:All published studies of CI in SS and contribution of two of our own patients who have not been reported previously.Methods:A comprehensive search of MEDLINE(via PubMed)was carried out in March 2020 using the following keywords and related entry terms:Susac's Syndrome,Cochlear Implantation.Results:Our search identified a total of five case reports of CI in SS.With the addition of our two patients reported here,we analyzed characteristics and outcomes in seven patients.Mean age at implantation was 30 years old(range 19-46),with six women and one man implanted.Mean time from onset of hearing loss to implantation was 17 months(range three months to four years).Best reported postoperative speech understanding was reported via different metrics,with six of seven patients achieving open set speech scores of 90% or better,and one subject performing at 68%.Vestibular symptoms were present preoperatively in four of seven patients(57%),with vestibular testing reported in two patients,and showing vestibulopathy in one patient.No complications were reported following cochlear implantation.Conclusion:Cochlear implantation is a viable option for hearing rehabilitation in patients with SS,with levels of attainment of open set speech comparable to other populations of CI candidates.

关键词： Susac's syndrome Cochlear implantation scoping review

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Clinical implications of single cell sequencing for bladder cancer

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Oncology Research 2024年第4期32卷 597-605页

作者： REZA YADOLLAHVANDMIANDOAB MEHRSA JALALIZADEH FRANCIELE APARECIDA VECHIA DIONATO KEINI BUOSI PATRÍCIA A.F.LEME LUCIANA S.B.DAL COL CRISTIANE F.GIACOMELLI ALEX DIAS ASSIS NASIM BASHIRICHELKASARI LEONARDO OLIVEIRA REIS UroScience School of Medical SciencesUniversity of CampinasUNICAMPCampinasSao Paulo13083-872Brazil ImmunOncology Pontifical Catholic University of CampinasPUC-CampinasCampinasSao Paulo13087-571Brazil

Bladder cancer(BC)is the 10th most common cancer worldwide,with about 0.5 million reported new cases and about 0.2 million deaths per year.In this scoping review,we summarize the current evidence regarding the clinical implications of single-cell sequencing for bladder cancer based on PRISMA guidelines.We searched PubMed,CENTRAL,Embase,and supplemented with manual searches through the Scopus,and Web of Science for published studies until February 2023.We included original studies that used at least one single-cell technology to study bladder cancer.Forty-one publications were included in the review.Twenty-nine studies showed that this technology can identify cell subtypes in the tumor microenvironment that may predict prognosis or response to immune checkpoint inhibition therapy.Two studies were able to diagnose BC by identifying neoplastic cells through single-cell sequencing urine samples.The remaining studies were mainly a preclinical exploration of tumor microenvironment at single cell level.Single-cell sequencing technology can discriminate heterogeneity in bladder tumor cells and determine the key molecular properties that can lead to the discovery of novel perspectives on cancer management.This nascent tool can advance the early diagnosis,prognosis judgment,and targeted therapy of bladder cancer.

关键词： Bladder cancer Urothelial carcinoma Transitional cell carcinoma Single-cell sequencing Tumor heterogeneity Immunotherapy scoping review Tumor microenvironment

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