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Non-contact wide-field viewing system-assisted scleral buckling surgery for retinal detachment in silicone oilfilled eyes

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 761-766页

作者： Su-Lan Wu Yi-Qi Chen Li-Jun Shen Jian-Bo Mao Li Lin Ji-Wei Tao Huan Chen Shi-An Zhang Jia-Feng Yu Chen-Xi Wang Center for Rehabilitation Medicine Department of OphthalmologyZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina The Affiliated Eye Hospital of Wenzhou Medical University in Hangzhou Hangzhou 310000Zhejiang ProvinceChina

AIM:To evaluate scleral buckling(SB)surgery using a noncontact wide-field viewing system and 23-gauge intraocular illumination for the treatment of rhegmatogenous retinal detachment in silicone oil(SO)-filled ***:Totally 9 patients(9 eyes)with retinal detachment in SO-filled eyes were retrospectively *** patients underwent non-contact wide-field viewing system-assisted buckling surgery with 23-gauge intraocular *** was removed at an appropriate time based on *** patients were followed up for at least 3mo after SO *** reattachment,complications,visual acuity and intraocular pressure(IOP)before and after surgery were ***:Patients were followed up for a mean of 8.22mo(3-22mo)after SO *** patients had retinal *** the final follow-up,visual acuity showed improvement for 8 patients,and no change for 1 *** IOP was high in 3 patients before surgery,but it stabilized after treatment;it was not affected in the other *** of the patients had infections,hemorrhage,anterior ischemia,or any other ***:This new non-contact wide-field viewing system-assisted SB surgery with 23-gauge intraocular illumination is effective and safe for retinal detachment in SO-filled eyes.

关键词： non-contact wide-field viewing system scleral buckling silicone oil-filled retinal detachment

Missed retinal breaks in rhegmatogenous retinal detachment

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International Journal of Ophthalmology(English edition) 2016年第11期9卷 1629-1633页

作者： Brijesh Takkar Shorya Azad Adarsh Shashni Amar Pujari Indrish Bhatia Rajvardhan Azad Dr. Rajendra Prasad Centre for Ophthalmic Sciences AIIMS New Delhi 110029 India Bharti Eye Hospital New Delhi 110029 India

AIM： To evaluate the causes and associations of missed retinal breaks（MRBs） and posterior vitreous detachment（PVD） in patients with rhegmatogenous retinal detachment（RRD）.METHODS： Case sheets of patients undergoing vitreo retinal surgery for RRD at a tertiary eye care centre were evaluated retrospectively. Out of the 378 records screened, 253 were included for analysis of MRBs and191 patients were included for analysis of PVD,depending on the inclusion criteria. Features of RRD and retinal breaks noted on examination were compared to the status of MRBs and PVD detected during surgery for possible ***： Overall, 27% patients had MRBs. retinal holes were commonly missed in patients with lattice degeneration while missed retinal tears were associated with presence of complete PVD. Patients operated for cataract surgery were significantly associated with MRBs（P =0.033） with the odds of missing a retinal break being1.91 as compared to patients with natural lens. Advanced proliferative vitreo retinopathy（PVR） and retinal bullae were the most common reasons for missing a retinal break during examination. PVD was present in 52% of the cases and was wrongly assessed in 16%. retinal bullae,pseudophakia/aphakia, myopia, and horse shoe retinal tears were strongly associated with presence of *** RRDs were rarely associated with PVD. CONCLUSION： Pseudophakic patients, and patients with retinal bullae or advanced PVR should be carefully screened for MRBs. Though Weiss ring is a good indicator of PVD, it may still be over diagnosed in some cases. PVD is associated with retinal bullae and pseudophakia, and inversely with traumatic RRD.

关键词： missed retinal breaks retinal detachment ocular examination posterior vitreous detachment retinalsurgery

Local dry vitrectomy combined with segmental scleral buckling and viscoelastic tamponade for rhegmatogenous retinal detachment with vitreous traction

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1713-1719页

作者： Ping Fei Hai-Ying Jin Qi Zhang Jie Peng Jia-Kai Li Jiao Lyu Tian Tian Zu-Peng Lu Jing Li Pei-Quan Zhao Department of Ophthalmology Xinhua HospitalAffiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China

AIM:To demonstrate local dry vitrectomy combined with segmental scleral buckling and viscoelastic tamponade for the treatment of partial rhegmatogenous retinal detachment(RRD)with local vitreous traction in patients at high-risk for proliferative vitreoretinopathy(PVR).METHODS:Eleven eyes of 11 patients were retrospectively studied,including 5 retinal dialysis and 6 retinal detachment(RD;5 eyes with peripheral retinal hole and I eye with giant tear).All patients exhibited partial RD and local vitreous *** local dry vitrectomy without conventional infusion and segmental scleral buckling was *** fluid was injected into the vitreous cavity if needed Demographic information,preoperative and postoperative complications,and outcomes were ***:The mean age of the patients at presentation was 26.55±*** 11 patients obtained retinal reattachment after a single surgical *** visual acuities were improved or remained stable in all *** of them developed complications,except for temporary mildly increased intraocular pressure in 3 ***:Combined local dry vitrectomy and segmental scleral buckling are effective for patients of RRD with local vitreous *** technique avoids many complications associated with regular surgery and was minimally invasive to both the external and internal eye.

关键词： dry vitrectomy retinal detachment scleral buckling

Reliability of the ocular trauma score for the predictability of traumatic and post-traumatic retinal detachment after open globe injury

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International Journal of Ophthalmology(English edition) 2021年第10期14卷 1589-1594页

作者： Simon Dulz Vasilis Dimopoulos Toam Katz Robert Kromer Eileen Bigdon Martin Stephan Spitzer Christos Skevas Department of Ophthalmology University Medical Center Hamburg-EppendorfHamburg 20246Germany Care-Vision Hamburg 20246Germany

AIM: To elucidate the question of whether the ocular trauma score(OTS) and the zones of injury could be used as a predictive model of traumatic and post traumatic retinal detachment(RD) in patients with open globe injury(OGI).METHODS: A retrospective observational chart analysis of OGI patients was performed. The collected variables consisted of age, date, gender, time of injury, time until repair, mechanism of injury, zone of injury, injury associated vitreous hemorrhage, trauma associated RD, post traumatic RD, aphakia at injury, periocular trauma and OTS in cases of OGI. RESULTS: Totally 102 patients with traumatic OGI with a minimum of 12 mo follow-up and a median age at of 48.6 y(range: 3-104 y) were identified. Final best corrected visual acuity(BCVA) was independent from the time of repair, yet a statistically significant difference was present between the final BCVA and the zone of injury. Severe trauma presenting with an OTS score Ⅰ(PⅢ. OGI associated RD was observed in 36/102 patients(35.3%), whereas post traumatic RD(defined as RD following 14 d after OGI) occurred in 37 patients(36.3%). OGI associated RD did not correlate with the OTS and the zone of injury(P=0.193), yet post traumatic RD correlated significantly with zone Ⅲ injuries(P=0.013). CONCLUSION: The study shows a significant association between lower OTS score and zone Ⅲ injury with lower final BCVA and a higher number of surgeries, but only zone Ⅲ could be significantly associated with a higher rate of RD.

关键词： intraocular foreign body ocular trauma score open globe injury retina retinal and vitreous surgery retinal detachment trauma

Application of immersion B-scan ultrasonography in diagnosis of complex retinal detachment,persistent hyperplastic primary vitreous and intraocular tumors

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International Journal of Ophthalmology(English edition) 2023年第3期16卷 388-395页

作者： Qing-Hua Yang An-Qi Liu Ying-Xin Qu Hong-Tao Zhang Bing Chen Yan Li Liang Jia Li-Qiang Wang Senior Department of Ophthalmology the Third MedicalCenter of PLA General HospitalBeijing 100039China Department of Ophthalmology Chinese Aerospace 731HospitalBeijing 100074China Medical Engineering Department of Medical Supply Center the Third Medical Center of PLA General HospitalBeijing100039China

AIM:To evaluate the diagnostic value of panoramic immersion B-scan ultrasonography(Pano-immersion B-scan,PIB)in complex retinal detachment(RD),persistent hyperplastic primary vitreous(PHPV)and intraocular ***:The clinical data of 44 patients collected from May 2012 to December 2019 in Chinese PLA General Hospital was retrospectively *** of these patients underwent PIB of the eye,because it was difficult to diagnose by routine ocular fundus examination,conventional ultrasound or/and ultrasonic biomicroscope(UBM)due to opacity of refractive media,pupillary occlusion,large involvement or special location of the *** imaging features of difficult cases in PIB were *** diagnosis accuracy rating of PIB were evaluated and contrasted with conventional ultrasound or UBM by the standard of intraoperative diagnosis or/and pathological ***:According to intraoperative diagnosis or pathological results as gold standard,among the 44 cases,there were 19 cases missed diagnosis,misdiagnosed or difficult-to-diagnose by conventional ultrasound or UBM,including 4 cases of long-standing RD difficult to diagnose,4 cases misdiagnosed,and 11 cases incompletely observed or miss *** diagnostic accuracy rate of PIB and conventional ultrasound or UBM were 100%(44/44)and 56.82%(25/44),and the sensitivity of them were 100%and 56.82%.All the patients underwent PIB and were diagnosed as RD(15 cases),retinal and choroidal detachment(4 cases),subchoroidal hematocele(1 case),vitreous opacity and/or organic membrane formation(4 cases),PHPV(12 cases),iris and/or ciliary body tumors(3 cases),and choroidal tumors(6 cases).According to the intraoperative diagnosis or pathological results,the diagnostic coincidence rate of PIB was 100%,which was significantly higher than conventional ultrasound and ***:PIB can help to accurately diagnose complex RD,PHPV,and intraocular masses with special location or/and excessive *** has important diagn

关键词： immersion ultrasonography panoramic retinal detachment persistent hyperplastic primary vitreous intraocular tumor

Amniotic membrane for covering high myopic macular hole associated with retinal detachment following failed primary surgery

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International Journal of Ophthalmology(English edition) 2022年第5期15卷 760-765页

作者： Gang Qiao Xiao-Juan Zhang Zi-Yan Tang Qiang-Xing Zou Chun-Mei He Xian-Ming Lei Long Zhao Yu Quan Hua-Qing Yang Kui Cao Wan-Jiang Dong Wanjiang Eye Hospital of Mianyang MianyangSichuan ProvinceChina

AIM:To evaluate the therapeutic effect of amniotic membrane(AM)for covering high myopic macular hole associated with retinal detachment following failed primary ***:Seventeen eyes of 17 patients whose axial length was more than 29 mm suffered from macular hole(MH)or MH associated with retinal detachment(RD),and had previously surgery of pars plana vitrectomy(PPV)with internal limiting membrane(ILM)peeling and silicone oil(SO)*** a year after the surgery,optical coherence tomography(OCT)showed that MH did not heal in all 17 eyes and RD was still maintained in 13 eyes of these 17 *** performed SO removal combined with AM covering on macular area and C3 F8 tamponade,and phacoemulsification combined with intraocular lens implantation simultaneously cataract *** followed up these patients for one ***:In all 17 eyes,SO was removed successfully,MHs were healed and RDs were *** eye(5.89%,1/17)had AM shifted half a month after surgery and underwent a second surgery to adjust the position of the AM and supplement C3 *** surgery,the visual acuity(VA)improved in 15 eyes(88.24%,15/17),no change in two eyes(11.76%,2/17).No serious complications occurred in all ***:AM covering is helpful to rescue the previous failure surgery of high myopic MH.

关键词： amniotic membrane high myopia macular hole retinal detachment

RNA interference targeting NOX4 protects visual function in an experimental model of retinal detachment by alleviating blood-retinal barrier damage

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International Journal of Ophthalmology(English edition) 2021年第1期14卷 50-56页

作者： Kai Dong Nan Yang Jie Ding Yuan-Ye Yan Li Lu Yi-Sai Wang Department of Ophthalmology Anhui Provincial HospitalAnhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Ophthalmology the Second People’s Hospital of HefeiHefei 230001Anhui ProvinceChina Department of Ophthalmology Wannan Medical CollegeWuhu 241001Anhui ProvinceChina Department of Ophthalmology Eye Centerthe First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina

AIM:To observe the effects of the inhibition of NADPH oxidase 4(NOX4)expression on the retinal vascular barriers and visual function after retinal detachment(RD).METHODS:RD model was established 3 wk after adenoassocianed virus vector *** retinal tissue was harvested 3 d after RD,and the death of retinal vascular endothelial cells and photoreceptors was observed using electron *** NOX4 expression was detected by Western *** microscopy was used to observe a retinal patch that had been perfused with Evans blue.A modified water maze test was used to detect the time required to find the platform on the water *** visual function of the rats was evaluated and reactive oxygen species(ROS)expression was detected by a fluorescence microplate ***:The retinal patch showed that NOX4 interference significantly reduced the destruction of the tight junctions between the retinal endothelium of RD rats and reduced *** blotting showed decreased expression of the NOX4 protein and decreased expression of ROS in retinal tissue;the Morris water maze test results showed that NOX4 interference significantly decreased the escape latency of the ***:NOX4 interference reduces the production of ROS in retinal vascular endothelial cells after experimental RD,thereby protecting the blood-retinal barrier and protecting visual function.

关键词： NOX4 adeno-associated virus retinal detachment blood-retinal barrier reactive oxygen species

Expression levels of ROS and Atg proteins in the vitreous in rhegmatogenous retinal detachment

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International Journal of Ophthalmology(English edition) 2023年第3期16卷 348-353页

作者： Nan Huang Xue-Yan Gao Jin-Ping Li Xing Lu Hua-Mei Zhu Kai Dong Department of Ophthalmology Xiaoxian People’s HospitalSuzhou 234000Anhui ProvinceChina Graduate School of Bengbu Medical College Bengbu233000Anhui ProvinceChina Department of Ophthalmology Eye Centerthe First AffiliatedHospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Graduate School of Anhui Medical University Hefei 230001Anhui ProvinceChina Hefei Aier Eye Hospital Hefei 230001Anhui ProvinceChina

AIM:To detect the concentrations of reactive oxygen species(ROS),transient receptor potential mucin-1(TRPML1),and autophagy-related(Atg)proteins(LC3-Ⅰ,LC3-Ⅱ,and Beclin1)in vitreous humor of patients with simple rhegmatogenous retinal detachment(RRD).METHODS:RRD patients enrolled as the RRD group,and patients with idiopathic macular hole(IMH)and idiopathic macular epiretinal membrane(IMEM)were enrolled as control *** levels of ROS,TRPML1,LC3-Ⅰ,LC3-Ⅱ,and Beclin1 in vitreous humor of patients in the RRD and control groups were detected by enzyme-linked immunosorbent assay(ELISA).RESULTS:The RRD group included 28 eyes 28 patients and had a higher concentration of ROS in vitreous humor(631.86±18.05 vs 436.34±108.22 IU/m L,Pretinal detachment(RD)extent(RD range≥1/2)was higher than that with a narrow RD extent(RD range<1/2,P<0.05).ROS concentration was negatively correlated with RD time(r=-0.46,P=0.01).The expression levels of LC3-Ⅰand Beclin1 significantly decreased in RRD(P<0.05),but there were no correlations with the RD time,RD extent,or macular ***:In eyes with RRD,the concentration of ROS in vitreous humor increases and the expression levels of Atg proteins decrease,reflecting possibly that autophagy is inhibited.

关键词： autophagy-related proteins reactive oxygen species vitreous body retinal detachment

Late contralateral recurrence of retinal detachment in incontinentia pigmenti:A case report

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World Journal of Clinical Cases 2022年第13期10卷 4171-4176页

作者： You-Ran Cai Yong Liang Xin Zhong Department of Ophthalmology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi ProvinceChina

BACKGROUND Incontinentia pigmenti(IP)is a rare X-linked genetic *** mainly manifests as skin lesions and causes problems in the eyes,teeth,bones,and central nervous *** the various ocular manifestations,the most severe with difficult recovery is retinal detachment(RD).Here,we report an unusual case of bilateral asymmetrical *** SUMMARY We present the case of an 11-year-old Chinese girl with IP who complained of sudden blurring of vision in the left *** that time,she had been blind in her right eye for 4 *** with traction was observed in both eyes.A massive retinal proliferative membrane,exudation,and hemorrhage were seen in the left *** performed vitrectomy in her left *** visual acuity recovered to 20/50,and her retina had flattened within 2 d after *** the 3-mo follow-up,we performed retinal laser treatment of the non-perfused retinal area in her left ***,her visual acuity returned to 20/32,and no new retinal abnormalities *** In patients with IP with fundal abnormalities in one eye,it is important to focus on the rate of fundal change in the other *** in its early stages can be effectively treated with timely vitrectomy and laser photocoagulation.

关键词： Incontinentia pigmenti Bilateral retinal detachment Shift code mutation Vitrectomy Case report