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Clinical and computed tomography features of adult abdominopelvic desmoplastic small round cell tumor

World Journal of Gastroenterology 2014年第17期20卷 5157-5164页

作者： Xun-Ze Shen Jian-Guo Zhao Jian-Jun Wu Fang Liu Department of Radiology Shaoxing People’s Hospital Shaoxing Hospital of Zhejiang University Department of Radiotherapy Shaoxing People’s Hospital Department of Radiology Second Affiliated Hospital of Medical SchoolZhejiang University Department of PAThology Shaoxing People’s Hospital

To investigate the clinical and computed tomography(CT)features of desmoplastic small round cell tumor(DSRCT),we retrospectively analyzed the clinical presentations,treatment and outcome,as well as CT manifestations of four cases of DSRCT confirmed by surgery and PAThology.The CT manifestations of DSRCT were as follows:(1)multiple soft-tissue masses or diffuse peritoneal thickening in the abdomen and pelvis,with the dominant mass usually located in the pelvic cavity;(2)masses without an apparent organbased primary site;(3)mild to moderate homogeneous or heterogeneous enhancement in solid area on enhanced CT;and(4)secondary manifestations,such as ascites,hePATic metastases,lymphadenoPAThy,hydronephrosis and hydroureter.The prognosis and overall survival rates were generally poor.Commonly used treatment strategies including aggressive tumor resection,polychemotherapy,and radiotherapy,showed various therapeutic effects.CT of DSRCT shows characteristic features that are helpful in diagnosis.Early discovery and complete resection,coupled with postoperative adjuvant chemotherapy,are important for prognosis of DSRCT.Whole abdominopelvic rather than locoregional radiotherapy is more effective for unresectable DSRCT.

关键词： Desmoplastic small round cell tumor Peritoneum PAT

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Helicobacter pylori and functional dyspepsia: An unsolved issue?

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World Journal of Gastroenterology 2014年第27期20卷 8957-8963页

作者： Angelo Zullo Cesare Hassan Vincenzo De Francesco Alessro Repici Raffaele Manta Silverio Tomao Bruno Annibale Dino Vaira Gastroenterology and Digestive Endoscopy "Nuovo Regina Margherita" Hospital Gastroenterology Unit "Riuniti" Hospital Digestive Endoscopy Unit "IRCCS Istituto Clinico Humanitas" 20089 Milan Italy Gastroenterology and Endoscopy Unit "Nuovo S Agostino" Hospital Oncology Unit "SM Goretti" Hospital Latina "Sapienza" University Department of Digestive and Liver Diseases "Sant’Andrea" Hospital "Sapienza" University Department of Internal Medicine and Gastroenterology University of Bologna

PATients with Helicobacter pylori(H. pylori) infection may complain of dyspeptic symptoms without presence of macroscopic lesions on gastroduodenal mucosa. Such a condition is usually recognized as functional dyspepsia, and different PAThogenetic mechanisms are involved. The role of H. pylori in these PATients is controversial. Several trials assessed the potential role of H. pylori eradication in improving dyspeptic symptoms, and data of some meta-analyses demonstrated that cure of infection is associated with a small(10%), but significant therapeutic gain as compared to placebo. The reason for which dyspeptic symptoms regress in some PATients following bacterial eradication, but persist in others remains unclear. Regrettably, trials included in the meta-analyses are somewhat different for study design, definition of symptoms, assessment of symptoms changes, and some may be flawed by potential pitfalls. Consequently, the information could be not consistent. We critically reviewed the main available trials, attempting to address future research in this

关键词： Helicobacter pylori Dyspepsia Symptoms Therapy PAT

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实现更优秀过程的关键

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流程工业 2017年第6期 46-46,48,49页

作者： Christian Knopf Axel Friese 不详 Glatt公司营销部

自从美国食品药品管理局（FDA）早在2003年决定在药品生产当中结合更多的过程分析技术以来，相关情形已经有了很大改变。但是，PAT倡导活动的目标并没有改变：直至今日，其目标仍然是优化药品生产和增进对过程的理解。在这段时期当中，... 详细信息

自从美国食品药品管理局（FDA）早在2003年决定在药品生产当中结合更多的过程分析技术以来，相关情形已经有了很大改变。但是，PAT倡导活动的目标并没有改变：直至今日，其目标仍然是优化药品生产和增进对过程的理解。在这段时期当中，市场上出现了适合这一应用领域且品类丰富的技术和传感器产品。

关键词：美国食品药品管理局药品生产 PAT 传感器技术

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一种可同步检测3种外源基因的多重PCR方法

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山西农业科学 2017年第1期45卷 37-40,88页

作者：尹全李忆邓强敬媛四川省农业科学院分析测试中心四川成都610066 四川民族学院环境与生命科学系四川康定626001 甘孜州农产品质量安全中心四川康定626000

为建立一种可同步检测3种外源基因的多重PCR方法,试验选择较常见的T-CaMV 35S,P-CaMV 35S和PAT这3个基因作为多重PCR检测对象,对多重PCR体系中引物浓度配比和引物退火温度进行优化。结果表明,多重PCR适宜的引物终浓度(μmol/L)配比T-CaM... 详细信息

为建立一种可同步检测3种外源基因的多重PCR方法,试验选择较常见的T-CaMV 35S,P-CaMV 35S和PAT这3个基因作为多重PCR检测对象,对多重PCR体系中引物浓度配比和引物退火温度进行优化。结果表明,多重PCR适宜的引物终浓度(μmol/L)配比T-CaMV 35S∶P-CaMV 35S∶PAT为0.2∶0.2∶0.2以及适宜的引物退火温度为56℃;采用优化后的反应体系对多重PCR体系灵敏度进行测试,结果显示,方法灵敏度为0.5 ng;通过利用建立的多重PCR方法对已知样品进行检测,结果表明,试验建立的多重PCR体系具有良好的可靠性。

关键词： T-CaMV 35S P-CaMV 35S PAT 多重PCR 检测

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