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Antioxidant and antimicrobial activities of selected medicinal plants from Algeria

Journal of Coastal Life Medicine 2014年第6期 478-483页

作者： Krimat Soumia Dob Tahar Lamari Lynda Boumeridja Saida Chelghoum Chabane Metidji Hafidha Laboratoire de Molécules Bio-Actives et Valorisation de la Biomasse ENS koubaAlgeria Laboratoire de Biologie des Systèmes Microbiens ENSKoubaAlgeria Departement of Natural sciences ENSKoubaAlgeria Laboratoire de chromatographie facultéde chimieUSTHBAlgiersAlgeria

Objective:To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal ***:Antioxidant activity of extracts was evaluated in terms of radical scavenging potential(2,2-diphenyl-1-picrylhydrazyl)and β-carotene bleaching *** phenolic contents and flavonoid contents were also *** activity of these plants was examined against Bacillus subtilis,Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida ***:The values of IC_(50) ranged from 4.30μg/mL to 486.6μg/mL for the DPPH method,while total antioxidant activity using β-carotene/linoleic acid bleaching assay ranged from 17.03%to 86.13%.It was found that Pistacia lentiscus showed the highest antioxidant capacities using DPPH assay(IC_(50)=4.30μg/mL),while Populus trimula,Origanum glandulosum,Centaurea calcitrapa,Sysimbrium officinalis and Rhamnus alaternus showed the highest percent of total antioxidant activity in β-carotene/linoleic acid bleaching *** phenolic and flavonoid contents ranged from 3.96 to 259.65 mg GAE/g extract and from 1.13 to 26.84 mg QE/g extract,*** most interesting antimicrobial activity was obtained from Sysimbrium officinalis,Rhamnus alaternus,Origanum glandulosum,Cupressus sempervirens,Pinus halipensis and Centaurea ***:The results indicated that the plants tested may be potential sources for isolation of natural antioxidant and antimicrobial compounds.

关键词： Antioxidant activity DPPH Antimicrobial activity disc diffusion method Total phenolic content Total flavonoid content

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Comparative study of hypoglycemic and antibacterial activity of organic extracts of four Bangladeshi plants

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Journal of Coastal Life Medicine 2016年第3期4卷 231-235页

作者： Mohammad Shah Hafez Kabir Shabbir Ahmad Md.Sofi Mahamoud Nishan Chakrabarty Md.Akramul Hoque Mohammed Munawar Hossain Md.Nazim Uddin Chy Mohammed Shoibe Department of Pharmacy International Islamic University ChittagongChittagongBangladesh

Objective:To examine hypoglycemic and antibacterial activity against some Gram-positive and Gram-negative bacteria of organic extracts of four Bangladeshi ***:An in vivo hypoglycemic effect on mice model was used to check the hypoglycemic effect of four Bangladeshi herbal organic extracts viz.,roots of Curculigo recurvata ***(Satipata)(***),leaf of Amorphophallus bulbifer Roxb.(Olkachu)(***),whole plant of Thunbergia grandiflora Roxb.(Nillata)(***)and leaf of Steudnera colocasiifolia ***(Yunnan)(***)using glibenclamide as a positive control and water as a negative *** were also tested for antibacterial activity on three Grampositive and four Gram-negative bacteria by disk diffusion ***,*** and *** were extracted with methanol and *** was extracted with ***:Among all the plant extract,only ethanol extract of *** leaves at 800 mg/kg dose significantly(P<0.01)reduced fasting glucose level in normal mice as compared to standard drug glibenclamide(5 mg/kg).Ethanol extract of *** leaves at 800 mg/kg dose decreased 20.28%of blood glucose level after 2 h of administration in normal mice,where glibenclamide decreased 39.63%.Methanol extract of *** didn’t show any zone of inhibition against the tested bacteria,but other three extracts showed a wide range of zone of ***,none of the extract showed antibacterial activity against all the tested *** extract of *** showed maximum zone of inhibition against Bacillus cereus[(10.50±0.50)mm],Salmonella typhi[(16.20±1.26)mm],Escherichia coli[(13.00±1.00)mm]and ethanol extract of *** showed maximum zone of inhibition against Staphylococcus aureus[(11.20±1.26)mm],Bacillus subtilis[(12.00±0.50)mm],Salmonella paratyphi[(10.80±0.29)mm].Only methanol extract of *** showed(8.50±0.50)mm and(7.20±0.76)mm zone of inhibition against P

关键词： Curculigo recurvata Steudnera colocasiifolia Hypoglycemic Antibacterial disc diffusion method

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