Antioxidant and antimicrobial activities of selected medicinal plants from Algeria

作     者：Krimat Soumia Dob Tahar Lamari Lynda Boumeridja Saida Chelghoum Chabane Metidji Hafidha 

作者机构：Laboratoire de Molécules Bio-Actives et Valorisation de la BiomasseENS koubaAlgeria Laboratoire de Biologie des Systèmes MicrobiensENSKoubaAlgeria Departement of Natural sciencesENSKoubaAlgeria Laboratoire de chromatographiefacultéde chimieUSTHBAlgiersAlgeria 

出 版 物：《Journal of Coastal Life Medicine》 (海岸生命医学杂志（英文版）)

年 卷 期：2014年第6期

页      面：478-483页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Supported by Algerian Ministry of Higher Education and Scientific Research 

主　　题：Antioxidant activity DPPH Antimicrobial activity Disc diffusion method Total phenolic content Total flavonoid content 

摘      要：Objective:To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal ***:Antioxidant activity of extracts was evaluated in terms of radical scavenging potential(2,2-diphenyl-1-picrylhydrazyl)and β-carotene bleaching *** phenolic contents and flavonoid contents were also *** activity of these plants was examined against Bacillus subtilis,Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida ***:The values of IC_(50) ranged from 4.30μg/mL to 486.6μg/mL for the DPPH method,while total antioxidant activity using β-carotene/linoleic acid bleaching assay ranged from 17.03%to 86.13%.It was found that Pistacia lentiscus showed the highest antioxidant capacities using DPPH assay(IC_(50)=4.30μg/mL),while Populus trimula,Origanum glandulosum,Centaurea calcitrapa,Sysimbrium officinalis and Rhamnus alaternus showed the highest percent of total antioxidant activity in β-carotene/linoleic acid bleaching *** phenolic and flavonoid contents ranged from 3.96 to 259.65 mg GAE/g extract and from 1.13 to 26.84 mg QE/g extract,*** most interesting antimicrobial activity was obtained from Sysimbrium officinalis,Rhamnus alaternus,Origanum glandulosum,Cupressus sempervirens,Pinus halipensis and Centaurea ***:The results indicated that the plants tested may be potential sources for isolation of natural antioxidant and antimicrobial compounds.