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Science China(Life Sciences) 2019年第5期62卷 713-724页

作者： Zengyi Chang School of Life Sciences State Key Laboratory of Protein and Plant Engineering Research Center for Protein Science Center of History and Philosophy of Science Peking University

The 2018 Nobel Prize in Chemistry was awarded one half to Dr. Frances Arnold (of California Institute of Technology,USA) for her work on 'directed evolution of enzymes', the other half to Dr. George Smith (of the University of Missouri, USA) and Sir Gregory Winter (of MRC Laboratory of Molecular Biology, UK) for their work on 'phage display of peptides and antibodies'.

关键词： The 2018 Nobel Prize in Chemistry towards desired properties via the construction of random libraries Engineering proteins

Inverse Design of Phononic Crystal with desired Transmission via a Gradient-Descent Approach

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Chinese Physics Letters 2023年第9期40卷 14-18页

作者：魏宇航贺达海 Department of Physics and Jiujiang Research Institute Xiamen UniversityXiamen 361005China

We propose a general approach based on the gradient descent method to study the inverse problem,making it possible to reversely engineer the microscopic configurations of materials that exhibit desired macroscopic ***,we demonstrate its application by identifying the microscopic configurations within any given frequency range to achieve transparent phonon transport through one-dimensional harmonic ***,we obtain the phonon transmission in terms of normal modes and find that the key to achieving phonon transparency or phonon blocking state lies in the ratio of the mode amplitudes at ends.

关键词： properties phonon desired

A New Method of desired Gait Synthesis for Biped Walking Robot Based on Ground Reaction Force

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High Technology Letters 2000年第4期6卷 33-38页

作者：张永学 Harbin Inst of Technology Harbin China

A new method of desired gait synthesis for biped walking robot based on the ground reaction force was proposed. The relation between the ground reaction force and joint motion is derived using the D’Almbert principle. In view of dynamic walking with high stability, the ZMP(Zero Moment Point)stability criterion must be considered in the desired gait synthesis. After that, the joint trajectories of biped walking robot are decided by substituting the ground reaction force into the aforesaid relation based on the ZMP criterion. The trajectory of desired ZMP is determined by a fuzzy logic based upon the body posture of biped walking robot. The proposed scheme is simulated and experimented on a 10 degree of freedom biped walking robot. The results indicate that the proposed method is feasible.

关键词： Biped walking robot desired gait synthesis ZMP Ground reaction force Fuzzy logic

Thickness bound for nonlocal wide-field-of-view metalenses

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Light(Science & Applications) 2022年第12期11卷 3018-3027页

作者： Shiyu Li Chia Wei Hsu Ming Hsieh Department of Electrical and Computer Engineering University of Southern CaliforniaLos AngelesCA 90089USA

Metalenses—flat lenses made with optical metasurfaces—promise to enable thinner,cheaper,and better imaging *** a sufficient angular field of view(FOV)is crucial toward that goal and requires a tailored incidentangle-dependent ***,we show that there is an intrinsic trade-off between achieving a desired broad-angle response and reducing the thickness of the *** the memory effect in disordered media,this thickness bound originates from the Fourier transform duality between space and *** can write down the transmission matrix describing the desired angle-dependent response,convert it to the spatial basis where its degree of nonlocality can be quantified through a lateral spreading,and determine the minimal device thickness based on such a required lateral *** approach is *** applied to wide-FOV lenses,it predicts the minimal thickness as a function of the FOV,lens diameter,and numerical *** bound is tight,as some inverse-designed multi-layer metasurfaces can approach the minimal thickness we *** work offers guidance for the design of nonlocal metasurfaces,proposes a new framework for establishing bounds,and reveals the relation between angular diversity and spatial footprint in multi-channel systems.

关键词： desired angular field

Dynamic Event-Triggered Control of Continuous-Time Systems With Random Impulses

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IEEE/CAA Journal of Automatica Sinica 2023年第12期10卷 2292-2299页

作者： Meng Yao Guoliang Wei the College of Science University of Shanghai for Science and TechnologyShanghai 200093China the Business School University of Shanghai for Science and TechnologyShanghai 200093China

In this paper,the networked control problem under event-triggered schemes is considered for a class of continuoustime linear systems with random *** order to save communication costs and lighten communication burden,a dynamic event-triggered scheme whose threshold parameter is dynamically adjusted by a given evolutionary rule,is employed to manage the transmission of data ***,the evolution of the threshold parameter only depends on the sampled measurement output,and hence eliminates the influence of impulsive signals on the event-triggered ***,with the help of a stochastic analysis method and Lyapunov theory,the existence conditions of desired controller gains are received to guarantee the corresponding input-to-state stability of the addressed ***,according to the semi-definite programming property,the desired controller gains are calculated by resorting to the solution of three linear matrix *** the end,the feasibility and validity of the developed control strategy are verified by a simulation example.

关键词： mechanism. desired hence

Orbit-Transfer Torque Switching

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Chinese Physics Letters 2022年第7期39卷 1-2页

作者： Yeliang Wang School of Integrated Circuits and Electronics MIIT Key Laboratory for Low-Dimensional Quantum Structure and DevicesBeijing Institute of TechnologyBeijing 100081China

In the post-Moore era, memory devices with smaller sizes, lower energy consumption, and higher reliability are desired. As a classic type of non-volatile memory, magnetic random-access memory(MRAM)is outstanding, sinc... 详细信息

关键词： sizes magnetic desired

A high-throughput data analysis and materials discovery tool for strongly correlated materials

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npj Computational Materials 2018年第1期4卷 138-146页

作者： Hasnain Hafiz Adnan Ibne Khair Hongchul Choi Abdullah Mueen Arun Bansil Stephan Eidenbenz John Wills Jian-Xin Zhu Alexander V.Balatsky Towfiq Ahmed Department of Physics Northeastern UniversityBostonMA 02119USA Department of Computer Science University of New MexicoAlbuquerqueNM 87131USA Theoretical Division Los Alamos National LaboratoryLos AlamosNM 87545USA The Information Science and Technology Institute Los Alamos National LaboratoryLos AlamosNM 87545USA Nordita KTH Royal Institute of Technology and Stockholm UniversityRoslagstullsbacken 23Stockholm SE-10691Sweden Department of Physics University of ConnecticutStorrsCT 06269USA Department of Mechanical Engineering Carnegie Mellon UniversityPittsburghPA 15213USA

Modeling of f-electron systems is challenging due to the complex interplay of the effects of spin–orbit coupling,electron–electron interactions,and the hybridization of the localized f-electrons with itinerant conduction *** complexity drives not only the richness of electronic properties but also makes these materials suitable for diverse technological *** this context,we propose and implement a data-driven approach to aid the materials discovery *** deploying state-of-the-art algorithms and query tools,we train our learning models using a large,simulated dataset based on existing actinide and lanthanide *** machine-learned models so obtained can then be used to search for new classes of stable materials with desired electronic and physical *** discuss the basic structure of our f-electron database,and our approach towards cleaning and correcting the structure data *** examples of the applications of our database include successful prediction of stable superstructures of double perovskites and identification of a number of physically-relevant trends in strongly correlated features of f-electron based materials.

关键词： database desired conduction

Nanomedicine in cancer therapy

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Signal Transduction and Targeted Therapy 2023年第9期8卷 3931-3964页

作者： Dahua Fan Yongkai Cao Meiqun Cao Yajun Wang Yongliang Cao Tao Gong Shunde Women and Children’s Hospital Guangdong Medical UniversityFoshan 528300China Department of Neurology Institute of Translational MedicineThe First Affiliated Hospital of Shenzhen UniversityShenzhen 518035China Lingang Laboratory Shanghai 200120China Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengdu 610064China

Cancer remains a highly lethal disease in the ***,either conventional cancer therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that cannot accurately distinguish malignant cells from healthy ones,giving rise to multiple undesired side *** advances in nanotechnology,accompanied by our growing understanding of cancer biology and nano-bio interactions,have led to the development of a series of nanocarriers,which aim to improve the therapeutic efficacy while reducing off-target toxicity of the encapsulated anticancer agents through tumor tissue-,cell-,or organelle-specific ***,the vast majority of nanocarriers do not possess hierarchical targeting capability,and their therapeutic indices are often compromised by either poor tumor accumulation,inefficient cellular internalization,or inaccurate subcellular *** Review outlines current and prospective strategies in the design of tumor tissue-,cell-,and organelle-targeted cancer nanomedicines,and highlights the latest progress in hierarchical targeting technologies that can dynamically integrate these three different stages of static tumor targeting to maximize therapeutic ***,we briefly discuss the current challenges and future opportunities for the clinical translation of cancer nanomedicines.

关键词： desired indices medicines

Single-atom alloying sprinkles magic over copper for exclusive CO_(2)conversion to pure formic acid

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Science China Chemistry 2022年第3期65卷 421-422页

作者： Zidong Wei The State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing Key Laboratory of Chemical Process for Clean Energy and Resource UtilizationSchool of Chemistry and Chemical EngineeringChongqing UniversityChongqing 400044China

CO_(2)electrolysis provides a promising solution to achieve carbon neutrality[1].With electric power from renewable energy,CO_(2)electrolysis brings considerable economic benefits by converting CO_(2)into diversified value-added chemicals,including CO,HCOOH,CH_(2),C_(2)H_(2),C_(2)H_(5)OH,and C_(3)H_(7)OH[2].Considering the profit of electrons per mole,HCOOH is one of the most desired products[3].

关键词： alloying copper desired

Efficient Spin-Flip between Charge-Transfer States for High-Performance Electroluminescence, without an Intermediate Locally Excited State

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Research 2024年第1期2023卷 339-349页

作者： Donghai Zhang Shanshan Jiang Xiaodong Tao Fulin Lin Lingyi Meng Xu-Lin Chen Can-Zhong Lu State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002China Fujian Science and Technology Innovation Laboratory for Optoelectronic Information of China FuzhouFujian 350108China Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstitutesChinese Academy of SciencesXiamenFujian 361021China University of Chinese Academy of Sciences Beijing 100049China

Thermally activated delayed fluorescence(TADF)materials with both high photoluminescence quantum yield(PLQY)and fast reverse intersystem crossing(RISC)are strongly desired to realize efficient and stable organic light-emitting diodes(OLEDs).Control of excited-state dynamics via molecular design plays a central role in optimizing the PLQY and RISC rate of TADF materials but remains ***,3 TADF emitters possessing similar molecular structures,similar high PLQYs(89.5%to 96.3%),and approximate energy levels of the lowest excited singlet states(S_(1)),but significantly different spin-flipping RISC rates(0.03×10^(6) s^(−1) vs.2.26×10^(6) s^(−1))and exciton lifetime(297.1 to 332.8μs vs.6.0μs)were systematically synthesized to deeply investigate the feasibility of spin-flip between charge-transfer excited states(^(3)CT–^(1)CT)transition.

关键词： transition lifetime desired