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Gelatin-Based Metamaterial Hydrogel Films with High conformality for Ultra-Soft Tissue Monitoring

Nano-Micro Letters 2024年第2期16卷 347-364页

作者： Yuewei Chen Yanyan Zhou Zihe Hu Weiying Lu Zhuang Li Ning Gao Nian Liu Yuanrong Li Jing He Qing Gao Zhijian Xie Jiachun Li Yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China School of Mechanical Engineering Guizhou UniversityGuiyang 550025People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineClinical Research Center for Oral Diseases of Zhejiang ProvinceKey Laboratory of Oral Biomedical Research of Zhejiang ProvinceCancer Center of Zhejiang UniversityHangzhou 310006People’s Republic of China

Implantable hydrogel-based bioelectronics(IHB)can precisely monitor human health and diagnose ***,achieving biodegradability,biocompatibility,and high conformality with soft tissues poses significant challenges for *** is the most suitable candidate for IHB since it is a collagen hydrolysate and a substantial part of the extracellular matrix found naturally in most *** study used 3D printing ultrafine fiber networks with metamaterial design to embed into ultra-low elastic modulus hydrogel to create a novel gelatin-based conductive film(GCF)with mechanical *** regulation of GCF nearly covers soft tissue mechanics,an elastic modulus from 20 to 420 kPa,and a Poisson’s ratio from-0.25 to *** negative Poisson’s ratio promotes conformality with soft tissues to improve the efficiency of biological *** GCF can monitor heartbeat signals and respiratory rate by determining cardiac deformation due to its high ***,the gelatin characteristics of the biodegradable GCF enable the sensor to monitor and support tissue *** GCF metamaterial design offers a unique idea for bioelectronics to develop implantable sensors that integrate monitoring and tissue repair and a customized method for endowing implanted sensors to be highly conformal with soft tissues.

关键词： Implantable hydrogel-based bioelectronics conformality 3D printing Metamaterial design

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具有增强一致性和透气性的无基底超薄表皮生物电极用于长期生理监测

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Science China Materials 2024年第5期67卷 1481-1490页

作者：李冠军公彦婷方诗镪游通邵瑞瑞姚兰前刘晨武春锦牛坚赖文勇 State Key Laboratory of Organic Electronics and Information Displays(SKLOEID) Institute of Advanced Materials(IAM)School of Chemistry and Life SciencesNanjing University of Posts&TelecommunicationsNanjing210023China

开发耐用且可靠的生物电极,用以采集高质量的生物电信号,已成为人体生理状态监测和人机交互领域的关键技术.然而,现有的生物电极多基于传统弹性基底,这导致了机械性能不匹配和低渗透性等问题,并且缺乏与生物皮肤类似的多方面属性和必要... 详细信息

开发耐用且可靠的生物电极,用以采集高质量的生物电信号,已成为人体生理状态监测和人机交互领域的关键技术.然而,现有的生物电极多基于传统弹性基底,这导致了机械性能不匹配和低渗透性等问题,并且缺乏与生物皮肤类似的多方面属性和必要的协同特性.本研究中,我们报道了一种新型的基于自支撑导电全聚合物薄膜的超薄表皮生物电极(ASU-EBE).该电极将超一致性、优异的拉伸性和透气性集成于一体,展现了约475 S cm^(-1)的高导电性,约48%的出色拉伸性,与生物组织界面的超一致性以及优异的透气性.该电极的电子和机械性能得到提升,这归功于在PEDOT:PSS中引入水溶性聚氧化乙烯,以调节分子间π-π堆积距离,并促进纳米纤维结构的形成.因此,ASU-EBE在与皮肤接触时的阻抗远低于标准凝胶电极,使其成为复杂日常环境下长期医疗监测的理想选择.

关键词： flexible bioelectronics epidermal bioelectrodes freestanding conductive films conformality breathability

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Parylene film for sidewall passivation in SCREAM process

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Science China(Technological Sciences) 2009年第2期52卷 357-362页

作者： JI Xu YU HuaiQiang HUANG XianJu LEI YingHua LI ZhiHong State Key Laboratory of Micro/Nano Fabrication Technology Institute of MicroelectronicsPeking UniversityBeijing 100871China

Trench sidewall passivation is a key step in the SCREAM (single crystal reactive etching and metallization) process for releasing suspended MEMS structures. In this paper, the parylene thin film is reported to serve as the passivation layer owing to its excellent conformality, chemical inertness, mechanical performance, and especially, low growth temperature. The deposited parylene films are characterized and the test structures are released through SCREAM process utilizing the parylene films as a passivation layer. The results show that as a passivation layer the parylene has more merits than the PECVD SiO2 film.

关键词： parylene sidewall passivation stress conformality SCREAM (single crystal reactive etching and metallization) process

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Runge-Kutta Multi-resolution Time-Domain Method for Modeling 3D Dielectric Curved Objects

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Transactions of Nanjing University of Aeronautics and Astronautics 2014年第4期31卷 440-444页

作者：朱敏曹群生赵磊王毅 College of Electronic and Information Engineering Nanjing University of Aeronautics and Astronautics Nanjing ASSEN Environment Technology Co.Ltd.

A conformal Runge-Kutta multi-resolution time-domain(C-RKMRTD)method is present and applied to model and analyze curved *** with the non-conformal method,the proposed method is more *** scattering analyses of the cylinder and ellipsoid are presented to validate the proposed *** numerical results demonstrate that the proposed scheme perform better than the MRTD method and other higher order methods with a higher accuracy.

关键词： conformality Runge-Kutta multi-resolution time-domain(MRTD) scattering

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ON DIMENSIONS OF SPACES OF BIVARIATE SPLINES WITH TRIANGULATIONS

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Science China Mathematics 1989年第6期32卷 674-684页

作者：王仁宏卢旭光 Jilin University Changchun Jilin University Changchun Department of Applied Mathematics Tsinghua University Beijing.

In this paper, the dimensional formulae of spline spaces S_k~μ(T) for all μ≥1, h≥4μ+ 1and arbitrary triangulation T are established with the use of conformality condition of themultivariate spline, plane graph theory and method of isomorphism of linear spaces. Fora kind of triangulation T = T(μ) as arbitrary as possible, the dimensional formula ofS_k~μ(T) for all k≥μ+ 1 is given. Especially, for μ= 1 or 2 this kind of triangulation willbe very useful to the approximation problem.

关键词： dimension bivariate spline conformality condition plane graph theory.

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