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chromoblastomycosis as a problem of the tropics

Asian Pacific Journal of Tropical Medicine 2009年第3期2卷 79-80页

作者： Bava Amadeo Javier Rodriguez Rios Elizabeth Troncoso Alcides Department of Micology La Plata National UniversityBuenos Aires State Department of Microbiology Parasitology and Infectious DiseasesSchool of MedicineBuenos Aires University

chromoblastomycosis can also cause severe but usually superficial lesions on the *** other deep mycosis, this chronic and disabling condition is seen in many tropical regions,including Argentina,where this man was ***... 详细信息

关键词： chromoblastomycosis Verrucous Lesiones

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Environmental siblings of black agents of human chromoblastomycosis

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Fungal Diversity 2014年第2期65卷 47-63页

作者： V.A.Vicente M.J.Najafzadeh Jiufeng Sun R.R.Gomes D.Robl S.G.Marques C.M.P.S.Azevedo G.S.de Hoog CBS-KNAW Fungal Biodiversity Centre P.O.Box 851673508AD UtrechtThe Netherlands Microbiology Parasitology and Pathology Post-graduation ProgramDepartment of Basic PathologyFederal University of ParanáCuritibaPRBrazil Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Peking University Health Science Center Research Center for Medical MycologyBeijingChina Sun-Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhouChina Second Medical Military University ShanghaiChina King Abdulassiz University Jeddah JeddahSaudi Arabia Department of Parasitology and Mycology and Cancer Molecular Pathology Research CenterGhaem HospitalSchool of MedicineMashhad University of Medical SciencesMashhadIran Guangdong Provincial Institute of Public Health Guangdong Provincial Center for Disease Control and PreventionGuangzhouChina Federal University of Maranhão University Hospital of the Federal University of MaranhãoSão LuísBrazil Cedro Laboratory and University Hospital of the Federal University of Maranhão São LuísBrazil Institute of Biomedical Sciences University of São Paulo(USP)CEP 05508-900 São PauloBrazil

Agents of human chromoblastomycosis,a skin disease almost exclusively caused by members of the order Chaetothyriales,are assumed to be traumatically inoculated into the skin with sharp environmental materials such as plant thorns or wooden splinters carrying the respective *** the supposition that such fungi should have their main habitat in the environment,we investigated the occurrence of black fungi in living areas of patients with *** South America Fonsecaea agents are prevalent as agents of the disease,while also related Cladophialophora species,known from other types of skin infections,are known from the *** environmental isolates were preliminarily selected as possible agents of chromoblastomycosis,based on *** from ITS sequence data isolates were attributed to the genera Cladophialophora,Cyphellophora,Exophiala,Fonsecaea,Phialophora,and Veronaea.A total of 45 fungi morphologically identified as Fonsecaea or Cladophialophora isolated from debris and thorns of living prickly plants in Brazil were processed for taxonomic *** analysis revealed that the isolates indeed belonged to the Chaetothyriales,but only rarely an agent of chromoblastomycosis was concerned;only two strains of *** and one *** were isolated from debris *** remaining isolates belonged to hitherto unknown molecular siblings of *** novel taxa are introduced.

关键词： Black yeasts Environmental isolation chromoblastomycosis Opportunistic fungi Virulence Infection route

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chromoblastomycosis:a tropical-subtropical fungal disease with pathognomonic features not to be neglected in a global health scenario

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Clinical Research Communications 2023年第1期6卷 1-4页

作者： Larissa de Andrade Defendi Giuliano Ferreira Morgantetti Guilherme Alencar de Medeiros Marcelo Balancin Department of Radiology Escola Paulista de MedicinaSão Paulo/SP 04024-002Brazil Department of Dermatopathology NORDD PathologyFortaleza/CE 60140-110Brazil Department of Pathology FOSPOncocentro FoundationSão Paulo/SP 04024-002Brazil

chromoblastomycosis(CBM)is a fungal disease,distributed in tropical and subtropical regions,affecting mainly rural *** is characterized by chronic skin lesions that may vary from nodular,tumorous,verrucous or plaque *** constitutional symptoms are rarely *** histological presentation may yield a pathognomonic feature,the Medlar(sclerotic)bodies,in which a typical brown to black pigment is depicted,explaining“copper pennies”as its *** this article,the case of a 56-year-old woman in the countryside of Brazil is reported,whose main complaint was a chronic leg ulcer for the past 8 *** left leg had a large,partially ulcerated plaque lesion was *** cultures were positive for the *** analysis demonstrated pseudoepitheliomatous hyperplasia,lymphohistiocytic infiltrate and sclerotic bodies(“copper pennies”).CBM’s epidemiological panorama,once established uniquely by geographical distribution,is transitioning to a global health issue,influenced by immunosuppressive conditions,global warming and *** scenario demands CBM to be widely considered as a differential diagnosis and may represent a clinical challenge in regions whose professionals have little expertise in infectious tropical diseases.

关键词： chromoblastomycosis fungal infection histopathology global health

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