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Chromoblastomycosis:a tropical-subtropical fungal disease with pathognomonic features not to be neglected in a global health scenario

作     者:Larissa de Andrade Defendi Giuliano Ferreira Morgantetti Guilherme Alencar de Medeiros Marcelo Balancin 

作者机构:Department of RadiologyEscola Paulista de MedicinaSão Paulo/SP 04024-002Brazil Department of DermatopathologyNORDD PathologyFortaleza/CE 60140-110Brazil Department of PathologyFOSPOncocentro FoundationSão Paulo/SP 04024-002Brazil 

出 版 物:《Clinical Research Communications》 (临床研究通讯)

年 卷 期:2023年第6卷第1期

页      面:1-4页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:chromoblastomycosis fungal infection histopathology global health 

摘      要:Chromoblastomycosis(CBM)is a fungal disease,distributed in tropical and subtropical regions,affecting mainly rural *** is characterized by chronic skin lesions that may vary from nodular,tumorous,verrucous or plaque *** constitutional symptoms are rarely *** histological presentation may yield a pathognomonic feature,the Medlar(sclerotic)bodies,in which a typical brown to black pigment is depicted,explaining“copper penniesas its *** this article,the case of a 56-year-old woman in the countryside of Brazil is reported,whose main complaint was a chronic leg ulcer for the past 8 *** left leg had a large,partially ulcerated plaque lesion was *** cultures were positive for the *** analysis demonstrated pseudoepitheliomatous hyperplasia,lymphohistiocytic infiltrate and sclerotic bodies(“copper pennies).CBM’s epidemiological panorama,once established uniquely by geographical distribution,is transitioning to a global health issue,influenced by immunosuppressive conditions,global warming and *** scenario demands CBM to be widely considered as a differential diagnosis and may represent a clinical challenge in regions whose professionals have little expertise in infectious tropical diseases.

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