Environmental siblings of black agents of human chromoblastomycosis
作者机构：CBS-KNAW Fungal Biodiversity CentreP.O.Box 851673508AD UtrechtThe Netherlands MicrobiologyParasitology and Pathology Post-graduation ProgramDepartment of Basic PathologyFederal University of ParanáCuritibaPRBrazil Institute for Biodiversity and Ecosystem DynamicsUniversity of AmsterdamAmsterdamThe Netherlands Peking University Health Science CenterResearch Center for Medical MycologyBeijingChina Sun-Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouChina Second Medical Military UniversityShanghaiChina King Abdulassiz University JeddahJeddahSaudi Arabia Department of Parasitology and Mycologyand Cancer Molecular Pathology Research CenterGhaem HospitalSchool of MedicineMashhad University of Medical SciencesMashhadIran Guangdong Provincial Institute of Public HealthGuangdong Provincial Center for Disease Control and PreventionGuangzhouChina Federal University of MaranhãoUniversity Hospital of the Federal University of MaranhãoSão LuísBrazil Cedro Laboratory and University Hospital of the Federal University of MaranhãoSão LuísBrazil Institute of Biomedical SciencesUniversity of São Paulo(USP)CEP 05508-900 São PauloBrazil
出 版 物：《Fungal Diversity》 (真菌多样性（英文）)
年 卷 期：2014年第65卷第2期
页 面：47-63页
核心收录：
学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1002[医学-临床医学] 100214[医学-肿瘤学] 0713[理学-生态学] 10[医学]
基 金：The work of Vania A.Vicente was supported by a Brazilian Government fellowship by financial support from the Brazilian Federal Agency for Support and Evaluation of Graduate Education-CAPES and Conselho Nacional de Pesquisa(CNPq).The work of Mohammad Javad Najafzadeh was supported by the Faculty of Medicine,Mashhad University of Medical Sciences,Mashhad,Iran
主 题：Black yeasts Environmental isolation Chromoblastomycosis Opportunistic fungi Virulence Infection route
摘 要：Agents of human chromoblastomycosis,a skin disease almost exclusively caused by members of the order Chaetothyriales,are assumed to be traumatically inoculated into the skin with sharp environmental materials such as plant thorns or wooden splinters carrying the respective *** the supposition that such fungi should have their main habitat in the environment,we investigated the occurrence of black fungi in living areas of patients with *** South America Fonsecaea agents are prevalent as agents of the disease,while also related Cladophialophora species,known from other types of skin infections,are known from the *** environmental isolates were preliminarily selected as possible agents of chromoblastomycosis,based on *** from ITS sequence data isolates were attributed to the genera Cladophialophora,Cyphellophora,Exophiala,Fonsecaea,Phialophora,and Veronaea.A total of 45 fungi morphologically identified as Fonsecaea or Cladophialophora isolated from debris and thorns of living prickly plants in Brazil were processed for taxonomic *** analysis revealed that the isolates indeed belonged to the Chaetothyriales,but only rarely an agent of chromoblastomycosis was concerned;only two strains of *** and one *** were isolated from debris *** remaining isolates belonged to hitherto unknown molecular siblings of *** novel taxa are introduced.
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