检索结果-南通市图书馆

Synthesis of Diverse Oxetane amino acids via Visible-Light-Induced Photocatalytic Decarboxylative Giese-Type Reaction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第12期42卷 1341-1346页

作者： Haoliang Shi Yi Wan Yongqiang Zhang Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism Shanghai Key Laboratory of New Drug Designand School of PharmacyEast China University of Science and TechnologyShanghai200237 China

The divergent synthesis of versatile 3,3′-disubstituted oxetane amino acids by utilizing visible-light-induced photocatalytic decarboxylative Giese-type reaction has been demonstrated.3-Methyleneoxetane-derived substrates are readily available in a single-step and highly reactive as radical acceptors,allowing the production of versatile oxetaneγ-andα-amino acids in high yields.A distinct ring strain release-driven radical addition mechanism was preliminarily *** preparative power was further highlighted by the application in the synthesis of oxetane-containing dipeptides and azetidine amino acids,as well as the transformation of the product into novel oxetane-containing spiro-heterocycle pharmacophore.

关键词： Photoredox catalysis Decarboxylative Giese-type reaction Oxetane amino acids amino acids Synthesis Radical reactions

Low crude protein formulation with supplemental amino acids for its impacts on intestinal health and growth performance of growing-finishing pigs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives

畜牧与生物技术杂志（英文版） 2024年第4期15卷 1590-1606页

作者： Marcos Elias Duarte Wanpuech Parnsen Shihai Zhang Márvio L.T.Abreu Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC 27695USA

Background Low crude protein(CP)formulations with supplemental amino acids(AA)are used to enhance intestinal health,reduce costs,minimize environmental impact,and maintain growth performance of ***,extensive reduction of dietary CP can compromise growth performance due to limited synthesis of non-essential AA and limited availability of bioactive compounds from protein supplements even when AA requirements are ***,implementing a low CP formulation can increase the net energy(NE)content in feeds causing excessive fat *** supplementation of functional AA,coupled with low CP formulation could further enhance intestinal health and glucose metabolism,improving nitrogen utilization,and growth *** experi-ments were conducted to evaluate the effects of low CP formulations with supplemental AA on the intestinal health and growth performance of growing-finishing pigs.Methods In Exp.1,90 pigs(19.7±1.1 kg,45 barrows and 45 gilts)were assigned to 3 treatments:CON(18.0％CP,supplementing Lys,Met,and Thr),LCP(16.0％CP,supplementing Lys,Met,Thr,Trp,and Val),and LCPT(16.1％CP,LCP+0.05％SID Trp).In Exp.2,72 pigs(34.2±4.2 kg BW)were assigned to 3 treatments:CON(17.7％CP,meeting the requirements of Lys,Met,Thr,and Trp);LCP(15.0％CP,meeting Lys,Thr,Trp,Met,Val,Ile,and Phe);and VLCP(12.8％CP,meeting Lys,Thr,Trp,Met,Val,lie,Phe,His,and Leu).In Exp.3,72 pigs(54.1±5.9 kg BW)were assigned to 3 treat-ments and fed experimental diets for 3 phases(grower 2,finishing 1,and finishing 2).Treatments were CON(18.0％,13.8％,12.7％CP for 3 phases;meeting Lys,Met,Thr,and Trp);LCP(13.5％,11.4％,10.4％CP for 3 phases;meeting Lys,Thr,Trp,Met,Val,lle,and Phe);and LCPG(14.1％,12.8％,11.1％CP for 3 phases;LCP+Glu to match SID Glu with CON).All diets had 2.6 Mcal/kg NE.Results In Exp.1,overall,the growth performance did not differ among *** LCPT increased(P＜0.05)Claudin-1 expression in the duodenum and *** LCP and LCPT increased(P＜0.05)CAT-1,4F2hc,and B0

关键词： amino acids Growing-finishing pigs Growth performance Intestinal health Low crude protein formulation Net energy NITROGEN-EXCRETION PATTERNS MONOSODIUM L-GLUTAMATE DIETARY-PROTEIN INSULIN-SECRETION GENE-EXPRESSION ADIPOSE-TISSUE L-TRYPTOPHAN PLASMA UREA WEIGHT-GAIN BLOOD UREA

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2023年第7期17卷 817-829页

作者： Benjing Xu Jinhang Dai Ziting Du Fukun Li Huan Liu Xingxing Gu Xingmin Wang Ning Li Jun Zhao Engineering Research Center for Waste Oil Recovery Technology and Equipment of Ministry of Education Chongqing Technology and Business UniversityChongqing 400067China College of Environment and Resources Chongqing Technology and Business UniversityChongqing 400067China Key Laboratory of Energy Resource Utilization from Agriculture Residue Academy of Agricultural Planning and EngineeringMinistry of Agriculture and Rural AffairsBeijing 100125China Department of Biology Hong Kong Baptist UniversityHong KongChina

amino acids are important nitrogen-containing chemicals that have a variety of ***,fermentation is the widely employed method to produce amino acids;however,the products are mostly limited to natural amino acids in the *** synthesis is an alternative approach for the synthesis of amino acids with different types and configurations,where the use of renewable biomass-based feedstocks is highly *** date,several lignocellulose and triacylglycerol-derived intermediates,typicallyα-keto acids andα-hydroxyl acids,have been transformed into amino acids via the amination reaction in the presence of additional nitrogen sources(i.e.,NH3·H2O).Making full use of inherent nitrogen in biomass(i.e.,chitin and protein)to produce amino acids avoids the use of extra nitrogen sources and meets the requirements of green chemistry,which is attracting increasing *** this review,we summarize different chemical-catalytic systems for the transformation of biomass to amino *** outlook on the challenges and opportunities for more effective production of amino acids from biomass by catalytic methods is provided.

关键词： biomass amino acids chitin nitrogen-containing compounds lignocellulose

Electrochemical detection of amino acids based on cucurbit[7]uril-mediated three-dimensional gold nanoassemblies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2023年第4期34卷 258-261页

作者： Shimi Liu Hao Zhang Yaqi Wang Yan Zeng Sobhan Chatterjee Feng Liang The State Key Laboratory of Refractories and Metallurgy School of Chemistry and Chemical EngineeringWuhan University of Science and TechnologyWuhan 430081China Improve-WUST Joint Laboratory of Advanced Technology for Point-of-Care Testing and Precision Medicine Wuhan University of Science and TechnologyWuhan 430081China

In this paper, cucurbit[7]uril(CB[7])-mediated three-dimensional gold nanoassemblies were successfully prepared to increase the loaded amount of CB[7] and enhance the electrochemical detection of amino acids. Particle sizes of gold nanoparticles(Au NPs) significantly affect stability and detection sensitivity of nanoassemblies. The volume of gold nanoassemblies first increased and then decreased with the increase of CB[7] concentration. The 3D gold nanoassemblies composed of 16 nm Au NPs and 100 μmol/L CB[7]had excellent stability and maximum volume, exhibiting more sensitive detection for a variety of amino acids. And the detection limits of aromatic amino acids are lower in virtue of the higher binding constant between aromatic amino acids and CB[7]. This study will develop and deepen our understanding of molecular recognition in amino acids detection.

关键词： Cucurbituril Gold nanoassemblies amino acids Electrochemical detection Host-guest interactions

Bidirectional role of synthetic musk tonalide as photosensitizer and activator on amino acids:Formation of sensitizer imine at aqueous chemistry interface of skin

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Eco-Environment & Health 2023年第1期2卷 32-39页

作者： Na Luo Yanpeng Gao Mei Wang Xiaolin Niu Guiying Li Taicheng An Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health Guangdong Key Laboratory of Environmental Catalysis and Health Risk ControlInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Guangzhou Key Laboratory of Environmental Catalysis and Pollution Control Key Laboratory of City Cluster Environmental Safety and Green Development of the Ministry of EducationSchool of Environmental Science and EngineeringGuangdong University of TechnologyGuangzhou 510006China

Personal care products(PCPs)inevitably come into contact with the skin in people’s daily life,potentially causing adverse effects on human *** adverse effects can be exacerbated under UV irradiation but are rarely *** this study,to clearly understand the damage of representative PCPs to human skin and their photochemical transformation behaviors,fragrance tonalide(AHTN)was measured in the presence of amino acids as a basic building block of human *** results showed that amino acids could decelerate the photochemical transformation rate of AHTN,increasing the likelihood of AHNT persisting on the skin surface and the health risk to the human ***,the interaction between amino acids and AHTN was *** could play bidirectional roles in damaging amino acids:the photosensitizer and reactive *** a photosensitizer,the ^(1)O_(2) generated from the AHTN photosensitization was partly employed to oxidative damage amino ***,by combining experiments with quantum chemical computation,the carbonyl group of the activator AHTN was found to be the active site to activate the N-containing group of amino *** activation mechanism was the electron transfer between AHTN and amino *** formed during the photochemical transformation of AHTN with histidine/glycine were the molecular initiating event for potential skin *** study reported for the first time that skin photosensitizer formation threatens human health during the photochemical transformation of AHTN.

关键词： Personal care products amino acids Photosensitive damage Electron transfer Imines

amino acids Functionalized Graphene Oxide for Enhanced Hydrophilicity and Antifouling Property of Poly(vinylidene fluoride) Membranes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2016年第7期34卷 805-819页

作者：李建华 shuang-shuang wang de-bin zhang xing-xing ni 张其清 Institute of Biomedical and Pharmaeeutical Teehnology Fuzhou University Fuzhou 350001 China

Herein, functionalized graphene oxide（GO） was prepared by the covalent functionalization with amino acids（lysine, glycine, glutamic acid and tyrosine） in this study. Zeta potential results demonstrated that covalent functionalization of GO with amino acids was favourable for their homogeneous dispersion in water and organic solvents. Based on the higher absolute value of zeta potential and the better dipersion stability of GO-lysine, the PVDF/GO-lysine hybrid membranes were then prepared via the phase inversion induced by immersion precipitation technique. SEM images showed a better pore diameter and porosity distribution on the PVDF/GO-lysine membrane surface. The zeta potential absolute value of the PVDF/GO-lysine membrane surface was higher than that of the virgin PVDF membrane. Furthermore, the PVDF/GO-lysine membranes surface exhibited good hydrophilicity. The water flux of PVDF/GO-lysine membranes can reach two times of that of the virgin PVDF membrane. And the BSA adsorbed amount on PVDF/GO-lysine surface was decreased to 0.82 mg/cm^2 for PVDF/GO-lysine-8% membrane. Filtration experiment results indicated that the fouling resistance was significantly improved for the PVDF/GO-lysine membranes. As a result, lysine functionalized GO will provide a promising method to fabricate graphene oxide based hybrid membranes with effective antifouling property and hydrophilicity.

关键词： PVDF membrane Graphene oxide amino acids Hydrophilicity Antifouling property

Differently synthesized gold nanoparticles respond differently to functionalization with L-amino acids

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Particuology 2020年第5期18卷 97-104页

作者： Darshana V.Havaldar Reshma V.Patil Disha N.Moholkar Priyanka S.Magdum Akash P.Vadrale Kiran D.Pawar School of Nanoscience and Biotechnology Shivaji UniversityKolhapurMaharashtraIndia

The potential utility of gold nanoparticles(AuNPs)synthesized via different methods for biomedical applications vary greatly due to inherent differences in their surface *** the present study,we investigated the functionalization of AuNPs synthesized by chemical reduction,plant extract,and bacteria-mediated methods with 22 L-amino *** produced by bacteria-mediated(B_AuNPs)and plant-mediated(P_AuNPs)methods showed good potential,as they were able to be functionalized with six(histidine,lysine,methionine,phenylalanine,tryptophan,and tyrosine)and four(cystine,tryptophan,tyrosine,and valine)amino acids,*** contrast,AuNPs produced by chemical reduction(C_AuNPs)were not found to be suitable for *** functionalization conditions were found to be amino acid concentration of 20-25 mM and neutral pH(7)for P_AuNPs,whereas B_AuNPs tolerated more variable *** electrophoretic mobility of P_AuNPs after functionalization indicated that these nanoparticles were less sensitive than B_AuNPs to the deviations from optimal conditions.A significant change in mobility was observed when B_AuNPs were functionalized with either methionine or ***,the results of this study suggest that the suitability of the three differently synthesized AuNPs with amino acids is in the following order:B_AuNPs>P_AuNPs>C_AuNPs.

关键词： Gold nanoparticles Biogenic synthesis amino acids Functionalization Electrophoretic mobility

Design of dual metal ions/dual amino acids integrated photoluminescent logic gate by high-molecular weight protein-localized Au nanoclusters

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2018年第1期11卷 311-322页

作者： Liu Liu Hui Jiang Xuemei Wang State Key Laboratory of Bioelectronics School of BiologicaI Science and Medical Engineering Southeast University Nanjing 210096 China

Proteins are excellent templates and stabilizers for Au nanoclusters （NCs） because of their abundant thiol groups and unique internal environments. However, high-molecular weight （MW） proteins with special quaternary structures are rarely reported as such templates. Considering that proteins may afford different spatial configurations as templates for Au NCs, we focused on alkaline phosphatase, catalase, and fibrinogen （MW range from 150 to 340 kDa） as direct templates for synthesizing Au NCs. We demonstrated that both Cu2~ and Hg2~ could induce photoluminescence （PL） quenching of these Au NCs, while their binding mech- anisms were different. Therefore, significant PL recovery by amino acids, e.g., histidine and cysteine, was observed for Cu2＋-treated Au NCs, but not Hg2＋-treated Au NCs, allowing for selective detection of Hg2＋ by using histidine as a masking agent. The detection ranges were 0.06-2.0 DM for Hg2＋ and 0.04-5.0 DM for Cu2＋, with low limits of detection of 0.02 and 0.01μM, respectively. The PL change showed opposite tendency for histidine and cysteine at higher concentrations, resulting in different PL outputs. Using dual metal ion and dual amino acid combinations, an integrated PL logic gate was fabricated. This work improves the understanding of the PL mechanisms of complicated protein-localized Au NCs.

关键词： gold nanoclusters proteins logic gate metal ions amino acids

Synthesis and Characterization of Rare Earth Complexes with Phthalanilic acids and amino acids

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2000年第1期18卷 18-21页

作者：石进超彭晓琦贾婴琪王振军 Department of Chemistry Northwest University Xi'an 710069 China

The complexes with the general formula REP3A· H2O [P = 2- (COO ) C6H4CONHC6H4X, X=2-CI, 4-Br; A=Gly, Ala, Leu; RE=Pr3+, Nd3+] were synthesized and characlerized by elemental analysis, IR and reflectance electronic spectra and TG methods. The results show that rare earth ion in each complex is coordinated by three oxygen atoms. One is from the amido and the other two from the hydroxyl in the carboxylate and the amino acid respectively, and each complex contains one coordinate water molecule. Condon parameters Fk, Lande parameters(4f), Nephelanxetic ratio(β), percentage convalency parameter(δ) and bonding parameter(b ) of the chelates were calculated from the reflectance electronic spectra, indicating certain covalent character in the metalligand bond. The apparent decompose activation energies were evaluated and the decompose mechanism were discussed.

关键词： rare earths praseodymium neodymium phthalanilic acid amino acids energy interaction parameter