Differently synthesized gold nanoparticles respond differently to functionalization with L-amino acids
不同地综合的金 nanoparticles 与 L 氨基的酸对 functionalization 不同地作出回应作者机构：School of Nanoscience and BiotechnologyShivaji UniversityKolhapurMaharashtraIndia
出 版 物：《Particuology》 (颗粒学报（英文版）)
年 卷 期：2020年第18卷第5期
页 面：97-104页
核心收录：
学科分类：07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学]
基 金：This research did not receive any specific grants from funding agencies in the public commercial or-not-for profit sectors
主 题：Gold nanoparticles Biogenic synthesis Amino acids Functionalization Electrophoretic mobility
摘 要：The potential utility of gold nanoparticles(AuNPs)synthesized via different methods for biomedical applications vary greatly due to inherent differences in their surface *** the present study,we investigated the functionalization of AuNPs synthesized by chemical reduction,plant extract,and bacteria-mediated methods with 22 L-amino *** produced by bacteria-mediated(B_AuNPs)and plant-mediated(P_AuNPs)methods showed good potential,as they were able to be functionalized with six(histidine,lysine,methionine,phenylalanine,tryptophan,and tyrosine)and four(cystine,tryptophan,tyrosine,and valine)amino acids,*** contrast,AuNPs produced by chemical reduction(C_AuNPs)were not found to be suitable for *** functionalization conditions were found to be amino acid concentration of 20-25 mM and neutral pH(7)for P_AuNPs,whereas B_AuNPs tolerated more variable *** electrophoretic mobility of P_AuNPs after functionalization indicated that these nanoparticles were less sensitive than B_AuNPs to the deviations from optimal conditions.A significant change in mobility was observed when B_AuNPs were functionalized with either methionine or ***,the results of this study suggest that the suitability of the three differently synthesized AuNPs with amino acids is in the following order:B_AuNPsP_AuNPsC_AuNPs.
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