检索结果-南通市图书馆

Plasma gelsolin level predicts acute kidney injury after cardiopulmonary bypass in infants and young children

World Journal of Pediatrics 2018年第2期14卷 143-150页

作者： Shan-Shan Shi Xiao-Jie Yue Dong-Yan Zhao Jia-Jie Fan Jian-Guo Xu Xi-Wang Liu Bao-Li Cheng Xiang-Ming Fang Jie Fan Qiang Shu Cardiac Intensive Care Unit The Children's Hospital of Zhejiang University School of MedicineHangzhouChina The Key Laboratory for Diagnosis and Therapy of Neonatal Diseases The Children's Hospital of Zhejiang University School of MedicineHangzhouChina Department of Thoracic and Cardiovascular Surgery The Children's Hospital of Zhejiang University School of MedicineHangzhouChina Department of Anesthesiology The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Surgery University of Pittsburgh School of MedicinePittsburghPAUSA

Background acute kidney injury(AKI)after cardiopulmonary bypass(CPB)is a common complication especially in pedi-atric *** gelsolin(pGSN)is an anti-inflammatory factor through binding with actin and pro-inflammatory cytokines in *** in pGSN has been reported in some pathologic *** purpose of the study was to determine the alterations of pGSN level in infants and young children after CPB and the role of pGSN as a predictor for the morbidity and severity of post-CPB *** Sixty-seven infants and young children at age≤3 years old undergoing CPB were prospectively *** levels were measured during peri-operative period with enzyme-linked immuno-sorbent assay and normalized with plasma total protein *** clinical characteristics of the patients were also *** In patients developing AKI,the normalized pGSN(pGSN_(N))levels significantly decreased at 6 h post-operation and remained low for 24 h post-operation as compared to the patients with *** at 6 h post-operation combining with CPB time presents an excellent predictive value for *** Decreased pGSN_(N)identifies post-CPB AKI in the patients≤3 years old,and is associated with adverse clini-cal *** findings suggest that circulating GSN in post-CPB patients may have beneficial effects on diminishing inflammatory responses.

关键词： acute kidney injury Cardiopulmonary bypass Infants Plasma gelsolin Young children

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Incidence, Mortality and Predictors of acute kidney injury in Patients with Cirrhosis:A Systematic Review and Meta-analysis

引用

Journal of Clinical and Translational Hepatology 2020年第2期8卷 135-142页

作者： Raseen Tariq Yousaf Hadi Khusdeep Chahal Sivani Reddy Habeeb Salameh Ashwani K.Singal Department of Medicine Rochester General HospitalRochesterNYUSA Department of Medicine University of West VirginiaMorgantownWVUSA University of Alabama at Birmingham BirminghamALUSA Department of Gastroenterology University of Texas Medical BranchGalvestonTXUSA Division of Gastroenterology and Hepatology University of South DakotaSanford School of MedicineSioux FallsSDUSA

Background and Aims:acute kidney injury(AKI)is com-mon in patients with cirrhosis but the incidence is heteroge-neous among *** performed a meta-analysis to describe the incidence of AKI and its impact on patient mor-tality in patients with *** also evaluated the admis-sion variables predicting development of ***:A systematic search of various databases was performed up to November ***-analyses were performed using ran-dom effects ***:Of 18,474 patients with cirrho-sis from 30 selected studies,5,648 developed AKI,with a pooled incidence of 29%(95% confidence interval[CI]:28-30%,I2 of 99%).In-hospital mortality assessed in eight stud-ies was six-fold higher among AKI patients,as compared to those without AKI(odds ratio[OR]6.72,95%CI:3.47-13,p0.0001).Mor-tality remained significantly high,at days 30 and 90 and even at 1-year follow up after development of *** 12 admission variables analyzed,model for end-stage liver disease score,Child-Pugh-Turcotte stage C,presence of ascites,and pres-ence of sepsis/septic shock were statistically significant risk factors for ***:AKI occurred in about 29% of patients with cirrhosis and is associated with a six-fold in-creased risk of in-hospital *** remained high even in long-term follow-up of 1 *** at risk for AKI development can be recognized at *** studies are needed to develop strategies for improving out-come of these patients.

关键词： acute kidney injury Cirrhosis Mortality Outcomes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Urinary neutrophil gelatinase-associated lipocalin(NGAL)and serum cystatin C measurements for early diagnosis of acute kidney injury in children admitted to PICU

引用

World Journal of Pediatrics 2018年第2期14卷 134-142页

作者： Jameela Abdulaziz Kari Mohamed Ahmed Shalaby Kholoud Sofyani Ahmad Saleh Sanad Albaraa Fuad Ossra Rayan Smeer Halabi Maha Hassan Aljuhani Wael Mohammad Toffaha Feras Aymen Moria Samar Sabry Hanan AbdelAziz Ahmed Khalid Abdulaziz Alhasan Sara Sharief Osama Safdar Pediatric Nephrology Center of Excellence and Department of Pediatrics King Abdulaziz University80215Jeddah 21589Kingdom of Saudi Arabia Pediatric Intensive Care Unit Department of PediatricsKing Abdulaziz UniversityJeddahKingdom of Saudi Arabia Pediatric Department Cairo UniversityGizaEgypt Department of Pediatrics College of MedicineKing Khalid University HospitalKing Saud UniversityRiyadhKingdom of Saudi Arabia

Background acute kidney injury(AKI)is common in critically ill children with significant mortality and *** creatinine is an insensitive and late biomarker compared to newly proposed AKI *** Prospective study in pediatric intensive care unit(PICU)over three months to compare between serum cystatin-C(s-Cys-C)and urinary neutrophil gelatinase-associated lipocalin(uNGAL)as AKI biomarkers at multiple time points with pediatric risk,injury,failure,loss,end-stage renal disease(pRIFLE)classification in diagnosing *** Forty children were *** these 40 children,22 developed AKI according to pRIFLE *** was no significant difference between AKI and non-AKI in age(P=0.29).Post cardiac surgery,renal insult was the main cause of AKI(27.3%).There was a twofold increased risk of incident AKI in those patients with high baseline uNGAL at PICU admission and almost a fourfold increased risk in patients with high baseline s-Cys-C at PICU *** levels were highly predictive of AKI during the follow-up period[area under the curve(AUC)=0.76,95%confidence interval(CI)0.61-0.92].The cutoff point with the highest correctly classified proportion was 223 ng/mL(≥12 centiles)which correctly predict 80.0%patients with AKI,with a corresponding sensitivity of 72.7%and a specificity of 89.9%.AUC for s-Cys-C was 0.86(95%CI 0.75-0.97),and the highest correctly classified proportion was 1009μg/L(≥13 centiles);75%of patients with AKI,with a corresponding sensitivity of 63.6%and a specificity of 88.9%.Conclusion uNGAL and s-Cys-C predicts AKI early in critically ill children.

关键词： acute kidney injury Neutrophil gelatinase-associated lipocalin Serum cystatin C

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Metabolic Acidosis in Critically Ill Cirrhotic Patients with acute kidney injury

引用

Journal of Clinical and Translational Hepatology 2019年第2期7卷 112-121页

作者： Dan-Qin Sun Lai Zhang Chen-Fei Zheng Wen-Yue Liu Kenneth I.Zheng Xiao-Ming Chen Ming-Hua Zheng Wei-Jie Yuan Department of Nephrology The Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical UniversityWuxiChina Department of Nephrology Shanghai General Hospital of Nanjing Medical UniversityShanghaiChina Department of Nephrology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouChina Department of Endocrinology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouChina NAFLD Research Center Department of Hepatologythe First Affiliated Hospital of Wenzhou Medical UniversityWenzhouChina Zhejiang Engineering Research Center of Intelligent Medicine The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouChina Institute of Hepatology Wenzhou Medical UniversityWenzhouChina Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province WenzhouChina

Background and Aims:The metabolic acid-base disorders have a high incidence of acute kidney injury(AKI)in critically ill cirrhotic patients(CICPs).The aims of our study were to ascertain the composition of metabolic acidosis of CICPs with AKI and explore its relationship with hospital ***:Three-hundred and eighty consecutive CICPs with AKI were eligible for the cohort ***,clinical and laboratory parameters were recorded and arterial acid-base state was analyzed by the Stewart and Gilfix ***:Net metabolic acidosis,lactic acidosis,acidosis owing to unmeasured anions,acidemia,and dilutional acidosis were less frequent in the non-survival group compared to the survival group of *** presence of acidemia,acidosis owing to unmeasured anions,and lactic acidosis were independently associated with increased risk of intensive care unit 30-day mortality,with hazard ratios of 2.11(95%confidence interval(CI):1.43–3.12),3.38(95%CI:2.36–4.84),and 2.16(95%CI:1.47–3.35),*** full adjustment for confounders,the relationship between acidosis owing to unmeasured anions with hospital mortality was still significant,with hazard ratio of 2.29(95%CI:1.22–4.30).Furthermore,arterial lactate concentration in combination with chronic liver failure-sequential organ failure assessment and BEUMA had the strongest ability to differentiate 30-day mortality(area under the receiver operating characteristic curve:0.79,95%CI:0.74–0.83).

关键词： Metabolic acidosis Critically ill cirrhotic patients acute kidney injury Hospital morality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Madelung’s disease with alcoholic liver disease and acute kidney injury: A case report

引用

World Journal of Clinical Cases 2021年第27期9卷 8199-8206页

作者： Ling Wu Ting Jiang Yan Zhang An-Qi Tang Li-Hua Wu Yu Liu Ming-Quan Li Liang-Bin Zhao Department of Nephrology Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Ultrasound Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina

BACKGROUND Madelung’s disease(MD)is a rare disorder of lipid metabolism,characterized by the growth of unencapsulated masses of adipose tissue symmetrically deposited around the neck,shoulders,or other sites around the *** pathological mechanism is not yet *** of the most common comorbidities in MD patients is liver disease,especially chronic alcoholic liver disease(CALD);however,no reports exist of acute kidney injury(AKI)with *** SUMMARY We report a 60-year-old man who presented with complaint of edema in the lower limbs that had persisted for 3 *** examination showed subcutaneous masses around the neck,and history-taking revealed the masses to have been present for 2 years and long-term heavy *** the clinical symptoms,along with various laboratory test results and imaging characteristics,a diagnosis was made of MD with acute exacerbation of CALD and *** patient was treated with liver function protection and traditional Chinese medicine,without surgical *** was advised to quit *** 10 d,the edema had subsided,renal function indicators returned to normal,liver function significantly improved,and size of subcutaneous masses remained *** In MD,concomitant liver or kidney complications are possible and monitoring of liver and kidney functions can be beneficial.

关键词： Madelung’s disease Multiple symmetric lipomatosis Drinking Alcoholic liver disease acute kidney injury Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis

引用

World Journal of Clinical Cases 2021年第35期9卷 10899-10908页

作者： Xian-Qiang Yu Hong-Bin Deng Yang Liu Cheng Qu Ze-Hua Duan Zhi-Hui Tong Yu-Xiu Liu Wei-Qin Li Medical School Southeast UniversityNanjing 210009Jiangsu ProvinceChina Department of Critical Care Medicine Nanjing Medical UniversityNanjing 210002Jiangsu ProvinceChina Department of Critical Care Medicine Nanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Critical Care Medicine General Hospital of Eastern Theater CommandNanjing 210002Jiangsu ProvinceChina

BACKGROUND Decreased serum magnesium(Mg2+)is commonly seen in critically ill *** is significantly more frequent in patients with severe acute *** kidney injury(AKI)in patients with acute pancreatitis(AP)is associated with an extremely high *** association underlying serum Mg2+and AKI in AP has not been *** To explore the association between serum Mg2+on admission and AKI in patients with *** A retrospective observational study was conducted in a cohort of patients(n=233)with AP without any renal injury before admission to our center from August 2015 to February *** characteristics on admission,severity score,laboratory values and in-hospital mortality were compared between patients with and without *** A total of 233 patients were included for analysis,including 85 with *** to patients without AKI,serum Mg2+level was significantly lower in patients with AKI at admission[OR=6.070,95%CI:3.374-10.921,P<0.001].Multivariate logistic analysis showed that lower serum Mg2+was an independent risk factor for AKI[OR=8.47,95%CI:3.02-23.72,P<0.001].CONCLUSION Our analysis indicates that serum Mg2+level at admission is independently associated with the development of AKI in patients with AP and may be a potential prognostic factor.

关键词： acute pancreatitis acute kidney injury Magnesium(Mg2+) kidney Predictor of acute kidney injury

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Management of acute kidney injury in gastrointestinal tumor:An overview

引用

World Journal of Clinical Cases 2021年第35期9卷 10746-10764页

作者： Yi-Qi Su Yi-Yi Yu Bo Shen Feng Yang Yu-Xin Nie Department of Nephrology Xiamen BranchZhongshan HospitalFudan UniversityXiamen 361015Fujian ProvinceChina Department of Medical Oncology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Nephrology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Pancreatic Surgery Pancreatic Disease InstituteHuashan HospitalShanghai Medical CollegeFudan UniversityShanghai 200040China

Gastrointestinal tumors remain a global health *** kidney injury(AKI)is a common complication during the treatment of gastrointestinal *** can cause a decrease in the remission rate and an increase in *** this review,we analyzed the causes and risk factors for AKI in gastrointestinal tumor *** possible mechanisms of AKI were divided into three groups:pretreatment,intrafraction and post-treatment *** and prevention measures were proposed according to various factors to provide guidance to clinicians and oncologists that can reduce the incidence of AKI and improve the quality of life and survival rate of gastrointestinal tumor patients.

关键词： Gastrointestinal tumor acute kidney injury Risk factors Treatment Preventive measures Enhanced recovery pathways

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimizing prevention of contrast-induced acute kidney injury in type 2 diabetic patients with at least moderate renal impairment

引用

Chinese Medical Journal 2012年第19期125卷 3365-3367页

作者： SHEN Wei-feng Department of Cardiology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

iabetes is a key risk factor for chronic kidney disease,^1 and patients with type 2 diabetes and coronary artery disease are at hlgla risk ot caralovascular events particularly when renal function is impaired.^2-4 Decision on how and when to proceed to coronary revascularization in an individual type 2 diabetic patient should be based on the extent of coronary disease, ischemic burden, ventricular function, as well as co-morbidities （e.g., renal insufficiency）.^5,6

关键词： acute kidney injury contrast-induced type 2 diabetic patients

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An effective model for predicting acute kidney injury after liver transplantation

引用

Hepatobiliary & Pancreatic Diseases International 2010年第3期9卷 259-263页

作者： Xu, Xiao Ling, Qi Wei, Qiang Wu, Jian Gao, Feng He, Zeng-Lei Zhou, Lin Zheng, Shu-Sen Zhejiang Univ Sch Med Affiliated Hosp 1 Dept Hepatobiliary & Pancreat Surg Hangzhou 310003 Zhejiang Peoples R China

BACKGROUND: acute kidney injury (AKI) is a common complication in the early period after liver transplantation (LT), posing an enormous obstacle to treatment efficiency and patient survival. However, the exact influencing factors of AKI are still unclear and a predictive model is desperately required in the clinic. METHODS: Data of 102 consecutive LTs were reviewed. A model for predicting AKI was established and further validated in a prospective study of 44-patients receiving LT. RESULTS: The incidence of AKI was 32.4%. AKI patients showed a significantly lower survival rate than non-AKI patients. Multivariate analysis demonstrated the independent influencing factors of AKI were preoperative serum creatinine >1.2 mg/dl, intraoperative urine output <= 60 ml/h, intraoperative hypotension status, and intraoperative use of noradrenaline. A model was then established and showed a sensitivity of 75.0%, a specificity of 93.8%, and an accuracy of 88.6% in predicting AKI. CONCLUSIONS: High preoperative serum creatinine, low intraoperative urine output, and intraoperative hypotension contribute to the development of AKI, and intraoperative use of noradrenaline serves as a protective factor. The predictive model could potentially facilitate early prediction and surveillance of AKI. (Hepatobilinty Pancreat Dis Int 2010; 9:259-263)

关键词： acute kidney injury liver transplantation risk factors complications prognosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Severe dengue associated with aseptic meningitis, acute kidney injury, and sudden sensorineural hearing loss: A case report

引用

Asian Pacific Journal of Tropical Medicine 2021年第4期14卷 187-190页

作者： Renan GM Diniz Elaine C dos Santos Gabriel CL Chagas Elizabeth F Daher Department of Internal Medicine Faculty of MedicineFederal University of CearaCearaBrazil Department of Intensive Care Unit Fortaleza General HospitalFortalezaCearaBrazil Post-Graduation Program in Medical Sciences Department of Internal MedicineFederal University of CearaFortalezaCearaBrazil

Rationale:Dengue is the most important human arboviral *** manifestations occur rarely in *** the best of our knowledge,there is only one reported case of dengue-associated sudden sensorineural hearing loss(SSNHL)in Brazil untill *** concerns:A 42-year-old man was presented to the emergency department with unconsciousness and generalized tonicclonic ***:Dengue-associated aseptic meningitis,acute kidney injury,and ***:The patient was treated with anticonvulsants and thiamine and underwent mechanical *** received combined ceftriaxone and acyclovir,which were later switched to meropenem,acyclovir and ampicillin empirically until culture results became *** also required hemodialysis and plasmapheresis sessions and fresh frozen plasma and buffy coat transfusions until definitive ***:The patient was discharged after improvement of his general condition and of his blood test results,but hearing loss remained.A six-month follow-up visit showed persistent ***:Dengue should be included in the differential diagnosis of patients from dengue-endemic areas presenting an acute febrile disease with neurological *** the best of our knowledge,this is the second reported case of dengueassociated SSNHL,suggesting an association between dengue and development of SSNHL.

关键词： Dengue Aseptic meningitis acute kidney injury Sensorineural hearing loss Deafness

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：