Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis

作     者：Xian-Qiang Yu Hong-Bin Deng Yang Liu Cheng Qu Ze-Hua Duan Zhi-Hui Tong Yu-Xiu Liu Wei-Qin Li 

作者机构：Medical SchoolSoutheast UniversityNanjing 210009Jiangsu ProvinceChina Department of Critical Care MedicineNanjing Medical UniversityNanjing 210002Jiangsu ProvinceChina Department of Critical Care MedicineNanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Critical Care MedicineGeneral Hospital of Eastern Theater CommandNanjing 210002Jiangsu ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2021年第9卷第35期

页      面：10899-10908页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：National Natural Science Foundation of China No.82070669 

主　　题：Acute pancreatitis Acute kidney injury Magnesium(Mg2+) Kidney Predictor of acute kidney injury 

摘      要：BACKGROUND Decreased serum magnesium(Mg2+)is commonly seen in critically ill *** is significantly more frequent in patients with severe acute *** kidney injury(AKI)in patients with acute pancreatitis(AP)is associated with an extremely high *** association underlying serum Mg2+and AKI in AP has not been *** To explore the association between serum Mg2+on admission and AKI in patients with *** A retrospective observational study was conducted in a cohort of patients(n=233)with AP without any renal injury before admission to our center from August 2015 to February *** characteristics on admission,severity score,laboratory values and in-hospital mortality were compared between patients with and without *** A total of 233 patients were included for analysis,including 85 with *** to patients without AKI,serum Mg2+level was significantly lower in patients with AKI at admission[OR=6.070,95%CI:3.374-10.921,P0.001].Multivariate logistic analysis showed that lower serum Mg2+was an independent risk factor for AKI[OR=8.47,95%CI:3.02-23.72,P0.001].CONCLUSION Our analysis indicates that serum Mg2+level at admission is independently associated with the development of AKI in patients with AP and may be a potential prognostic factor.