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Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children:analysis of 571 patients

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World Journal of Pediatrics 2024年第3期20卷 250-258页

作者： Min He Jia-Bin Cai Xuan Wu Yin-Bing Tang Jin-Yan Wang Jun-Qin Mao Ji-Jun Chen Li-Feng Zhang zhong-hai guan Jie-Ni Xiong Wan-Xin Peng Jin-Hu Wang Ting Tao Pediatric Cancer Research Center National Clinical Research Center for Child HealthHangzhouChina Department of Surgical Oncology Children's HospitalZhejiang University School of MedicineHangzhouChina Cancer Center Zhejiang UniversityNo.3333 Binsheng RodeHangzhouChina

Background Surgery plays an important role in the treatment of *** complications may impact the course of neuroblastoma *** date,comprehensive analyses of complications and risk factors have been *** Patients with retroperitoneal neuroblastoma undergoing tumor resection were retrospectively analyzed between 2014 and *** data collected included clinical characteristics,operative details,operative complications and postopera-tive *** factors for perioperative complications of retroperitoneal neuroblastoma were *** A total of 571 patients were enrolled in this *** complications were observed in 255(44.7%)*** leakage(28.4%),diarrhea(13.5%),and injury(vascular,nerve and organ;7.5%)were the most frequent *** were three operation-related deaths(0.53%):massive hemorrhage(n=1),biliary tract perforation(n=1)and intestinal necrosis(n=1).The presence of image-defined risk factors(IDRFs)[odds ratio(OR)=2.09,P<0.01],high stage of the International Neuroblastoma Risk Group staging system(INRGSS)(OR=0.454,P=0.04),retroperitoneal lymph node metastasis(OR=2.433,P=0.026),superior mesenteric artery encasement(OR=3.346,P=0.003),and inferior mesenteric artery encasement(OR=2.218,P=0.019)were identified as independent risk factors for perioperative *** Despite the high incidence of perioperative complications,the associated mortality rate was quite ***-perative complications of retroperitoneal neuroblastoma were associated with IDRFs,INRGSS,retroperitoneal lymph node metastasis and vascular *** with high-risk factors should receive more serious attention during surgery but should not discourage the determination to pursue total resection of neuroblastoma.

关键词： Complication Neuroblastoma Risk factors Surgery

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Hot versus cold subduction initiation

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National Science Review 2024年第2期11卷 101-102页

作者： zhong-hai Li Key Laboratory of Computational Geodynamics College of Earth and Planetary SciencesUniversity of Chinese Academy of Sciences

In the framework of plate tectonics, subduction initiation(SI) indicates the birth of a plate convergent boundary, which is a key point of plate tectonics and Wilson's cycle; however, its dynamic process is not well c... 详细信息

关键词： DRIVEN CRUST

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Paraplegia after transcatheter artery chemoembolization in a child with clear cell sarcoma of the kidney:A case report

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World Journal of Clinical Cases 2020年第11期8卷 2332-2338页

作者： Jia-Bin Cai Min He Fa-Liang Wang Jie-Ni Xiong Jun-Qing Mao zhong-hai guan Lin-Jie Li Jin-Hu Wang Department of Surgical Oncology The Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310053Zhejiang ProvinceChina

BACKGROUND Transcatheter arterial chemoembolization(TACE)is a common treatment for inoperable malignant renal ***,a series of complications may follow the TACE *** cord injury caused by the embolization of intercostal or lumbar arteries is extremely *** SUMMARY We describe a case with quite uncommon spinal cord injury after TACE in a 3-year-old child with clear cell sarcoma of the *** impairment beneath the T10 dermatomes and paraplegia on the day after TACE were found in this ***,sustained paraplegia still existed for more than 2 mo after TACE despite the large dose of steroids and supportive *** We should draw attention to an uncommon complication of paraplegia after TACE treatment in malignant renal *** it is rare,the result is disastrous.

关键词： Complication Chemoembolization Spinal cord injury Clear cell sarcoma of the kidney Pediatric Case report

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High-performance Si/VO_(2)-nanorod heterojunction photodetector based on photothermoelectric effect for detecting human radiation

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Rare Metals 2024年第3期43卷 1177-1185页

作者： Fu-hai Guo Lan-zhong Hao Wei-Zhuo Yu Si-Qi Li guan-Chu Liu Jing-Yi Hao Yun-Jie Liu College of Science China University of PetroleumQingdao266580China School of Materials Science and Engineering China University of PetroleumQingdao266580China

As a typical candidate of optoelectronic materials,vanadium dioxide(VO_(2))has wide applications in photodetectors(PDs),but is still challenging in largely enhancing the photodetecting performance for low-power human ***,high-performance Si/VO_(2)nanorods(NRs)heterojunction PDs based on the photothermoelectric(PTE)effect are *** uniform VO_(2)-NRs array films were deposited on Si by using magnetron sputtering technique,and a Si/VO_(2)heterojunctions were *** device exhibits a four-stage photoresponse and broadband photoresponse from ultraviolet to long-wavelength *** from the unique nanorods structure and the strong PTE effect,the fabricated device exhibits a large enhancement of the photodetecting performance,showing an ultrahigh photodetectivity of 1.6×10^(13)Jones and ultrafast response rates with a risingedge time of~65.0μs,three orders of magnitude higher than other VO_(2)-based ***,the device exhibits unique abilities to detect human radiation even when the human fingers are far away from the device surface up to 10.0 ***,the fabricated Si/VO_(2)devices can also be applied as breath sensors to distinguish different breathing *** results supply an effective route to design high-performance photodetectors toward detecting human thermal radiation and respiration.

关键词： Vanadium dioxide Heterojunction Photodetector Photothermoelectric Human radiation and respiration sensing

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Neoadjuvant transcatheter arterial chemoembolization and systemic chemotherapy for the treatment of undifferentiated embryonal sarcoma of the liver in children

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World Journal of Clinical Cases 2022年第19期10卷 6437-6445页

作者： Min He Jia-Bin Cai Can Lai Jun-Qing Mao Jie-Ni Xiong zhong-hai guan Lin-Jie Li Qiang Shu Mei-Dan Ying Jin-Hu Wang Department of Surgical Oncology The Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052Zhejiang ProvinceChina Department of Radiology The Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052Zhejiang ProvinceChina Cancer Center Zhejiang UniversityHangzhou 310058Zhejiang ProvinceChina

BACKGROUND Undifferentiated embryonal sarcoma of the liver(UESL)is a rare and aggressive mesenchymal tumor in ***,we describe our experience in neoadjuvant therapy(NAT)and subsequent surgery for the treatment of UESL in *** To evaluate the efficacy of NAT and explore a new choice for successful operation of UESL in *** We retrospectively analyzed six patients newly diagnosed with unresectable UESL who received NAT and then surgery at our center between January 2004 and December *** tumor was considered unresectable if it involved a large part of both lobes of the liver or had invaded the main hepatic vessels or inferior vena *** NAT included preoperative transcatheter arterial chemoembol ization(TACE)and systemic *** patients were 4 boys and 2 girls with a mean age of 7 *** longest tumor at presentation ranged from 8.6 to 14.8 cm(mean,12 cm).Extrahepatic metastases were present in 2 *** systemic chemotherapy was administered 3 wk after *** resection was performed 3 wk after one or two cycles of *** patients received systemic chemotherapy after *** All patients successfully underwent NAT and complete *** tumor volumes decreased by 18.2%–68.7%,with a mean decrease of 36%after 1 cycle of NAT(t=3.524,P=0.017).According to the Response Evaluation Criteria In Solid Tumors criteria,4 patients had a partial response and underwent surgery,while 2 had stable disease and received another cycle of NAT before *** tumor necrosis was seen on pathological examination of the surgical specimen:>90%necrosis in two,>50%necrosis in three,and 25%necrosis in 1,with an average of 71.8%.Post-NAT complications included fever,nausea and vomiting,and mild bone marrow *** alanine transaminase levels occurred in all patients,which returned to normal within 7–10 d after *** cardiac or renal toxicity,severe hepatic dysfunction,bleeding and nontarget e

关键词： Undifferentiated embryonal sarcoma of the liver Unresectable Neoadjuvant therapy Transcatheter arterial chemoembolization Systemic chemotherapy

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Grating-free autofocus for single-pixel microscopic imaging

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Photonics Research 2024年第6期12卷 1313-1321页

作者： guan WANG HUAXIA DENG YU CAI MENGCHAO MA XIANG zhong XINGLONG GONG CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230027China School of Instrument Science and Opto-electronics Engineering Hefei University of TechnologyHefei 230009China

As a computational technology,single-pixel microscopic imaging(SPMI)transfers the target’s spatial information into a temporal *** traditional focusing method of imaging before evaluation is not applicable to the SPMI *** propose a grating-free autofocus strategy derived from the physical mechanism of optical *** the amplitude information of just one high-frequency point in the spectrum is all that is needed to achieve fast autofocus with the SPMI ***,only four patterns need to be cyclically projected,enabling efficient localization of the focal plane based on the measurement *** demonstrate SPMI autofocus experiments at micrometer and even nanometer depths of *** proposed method can be extended to achieve SMPI autofocus with invisible optical pattern illumination.

关键词： optical system illumination

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Promoted hydrogenation of CO2 to methanol over single-atom Cu sites with Na+-decorated microenvironment

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National Science Review 2024年第6期11卷 264-272页

作者： Li-Li Ling Xinyu guan Xiaoshuo Liu Xiao-Mei Lei zhongyuan Lin hai-Long Jiang Hefei National Research Center for Physical Sciences at the Microscale Department of Chemistry University of Science and Technology of China School of Energy and Power Engineering North China Electric Power University School of Energy and Environment Southeast University

Although single-atom Cu sites exhibit high efficiency in CO2hydrogenation to methanol,they are prone to forming Cu nanoparticles due to reduction and aggregation under reaction conditions,especially at high ***,single-atom Cu sites stabilized by adjacent Na+ions have been successfully constructed within a metal-organic framework（MOF）-based catalyst,namely *** is found that the electrostatic interaction between the Na+and Hδ-species plays a pivotal role in upholding the atomic dispersion of Cu in MOF-808-NaCu during CO2hydrogenation,even at temperatures of up to 275℃.This exceptional stabilization effect endows the catalyst with excellent activity(306 g·kgcat-1·h-1),high selectivity to methanol（93%） and long-term stability at elevated reaction temperatures,far surpassing the counterpart in the absence of Na+（denoted as MOF-808-Cu）.This work develops an effective strategy for the fabrication of stable single-atom sites for advanced catalysis by creating an alkali-decorated microenvironment in close proximity.

关键词： single-atom sites metal–organic framework CO2 hydrogenation heterogeneous catalysis alkali-metal decoration

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State and parameter identification of linearized water wave equation via adjoint method

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Science China(Information Sciences) 2024年第10期67卷 283-297页

作者： Yang YU Cheng-zhong XU hai-Long PEI Jinpeng YU School of Automation Qingdao University LAGEP Batiment CPE University Claude Bernard-Lyon 1 School of Automation Science and Engineering Key Laboratory of Autonomous Systems and Networked ControlMinistry of Education Guangdong Engineering Technology Research Center of Unmanned Aerial Vehicle SystemSouth China University of Technology

In this paper, we focus on the state and parameter identification problem of a hydrodynamical system. This system is modeled as a linearized water wave equation(LWWE), a hyperbolic state-space model coupled with a Laplace equation. We assume that the wave elevation at two distinct points is the only measurement of water waves. We show that the state and water depth can be reconstructed from this point measurement records. The identification problem is recast as an optimization problem over an infinite-dimensional space. We propose the adjoint method-based identification algorithm to generate an estimated state and water depth. We then performed a numerical simulation to show the effectiveness of our designed algorithm by comparing it with existing studies.

关键词： linearized water wave equation (LWWE) point observation state estimation parameter identification adjoint method numerical simulation

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Free-moving-state microscopic imaging of cerebral oxygenation and hemodynamics with a photoacoustic fiberscope

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Light(Science & Applications) 2024年第1期13卷 33-46页

作者： Xiaoxuan zhong Yizhi Liang Xiaoyu Wang Haoying Lan Xue Bai Long Jin Bai-Ou guan guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications Institute of Photonics TechnologyJinan UniversityGuangzhou510632China

We report the development of a head-mounted photoacoustic fiberscope for cerebral imaging in a freely behaving *** 4.5-gram imaging probe has a 9-µm lateral resolution and 0.2-Hz frame rate over a 1.2-mm wide *** probe can continuously monitor cerebral oxygenation and hemodynamic responses at single-vessel resolution,showing significantly different cerebrovascular responses to external stimuli under anesthesia and in the freely moving *** example,when subjected to high-concentration CO_(2) respiration,enhanced oxygenation to compensate for hypercapnia can be visualized due to cerebral regulation in the freely moving *** studies exhibit significantly weakened compensation capabilities in obese *** new imaging modality can be used for investigating both normal and pathological cerebrovascular functions and shows great promise for studying cerebral activity,disorders and their treatments.

关键词： cerebral anesthesia moving

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Reversal of complete atrioventricular block in dialysis patients following parathyroidectomy:A case report

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World Journal of Clinical Cases 2024年第7期12卷 1313-1319页

作者： Shan-Shan Xu Li-hai Hao Yan-Meng guan Hemodialysis Center Weifang People’s HospitalWeifang 261041Shandong ProvinceChina

BACKGROUND Refractory secondary hyperparathyroidism(SHPT)is a common complication observed in patients with end-stage renal disease and can result in ectopic *** calcification involving the heart valves and the conduction system can easily lead to arrhythmias,including atrioventricular *** case report describes a maintenance hemodialysis patient with refractory SHPT resulting in a complete atrioventricular block(CAVB),which was eventually reversed to a first-degree atrioventricular *** SUMMARY We present the case of a 31-year-old Asian female who was receiving maintenance hemodialysis because of lupus *** developed SHPT,and an electrocardiogram revealed a first-degree atrioventricular ***,she underwent parathyroidectomy(PTX)with ***,a few years later,she developed SHPT again,and an electrocardiogram revealed a CAVB.A few years after the second PTX surgery,the calcification of the left atrium and left ventricle improved,and her CAVB was *** This case revealed that metastatic cardiac calcification can result in complete atrioventricular *** parathyroid surgery,calcification of the cardiac conduction system improved,leading to reversal of the atrioventricular *** is important for dialysis patients to optimize intact parathyroid hormone therapy and pay attention to calcification metastasis.

关键词： Secondary hyperparathyroidism Ectopic calcification Atrioventricular block Reversal Case report

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