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The effect of scrotal versus inguinal orchiopexy on the testicular function of children with clinically palpable,inguinal undescended testis:a randomized controlled trial

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Asian Journal of Andrology 2023年第6期25卷 745-749页

作者： Wen-Hua Huang Long-Yao Xu Shu-Shen chen zhi-qiang chen Xu Cui Chao-Ming Zhou Department of Pediatric Surgery Fujian Maternity and Child Health HospitalCollege of Clinical Medicine for Obstetrics&Gynecology and PediatricsFujian Medical UniversityFuzhou 350005China Department of Urinary Surgery Fujian Children’s HospitalCollege of Clinical Medicine for Obstetrics&Gynecology and PediatricsFujian Medical UniversityFuzhou 350001China

To compare the impact of the scrotal vs inguinal orchidopexy approach on the testicular function of infants with cryptorchidism,a randomized controlled trial was conducted involving boys who were 6–12 months old at surgery and were diagnosed with clinically palpable,inguinal undescended testis.Between June 2021 and December 2021,these boys at Fujian Maternity and Child Health Hospital(Fuzhou,China)and Fujian Children’s Hospital(Fuzhou,China)were enrolled.Block randomization with a 1:1 allocation ratio was employed.The primary outcome was testicular function assessed by testicular volume,serum testosterone,anti-Müllerian hormone(AMH),and inhibin B(InhB)levels.Secondary outcomes included operative time,amount of intraoperative bleeding,and postoperative complications.Among 577 screened patients,100(17.3%)were considered eligible and enrolled in the study.Of the 100 children who completed the 1-year follow-up,50 underwent scrotal orchidopexy and 50 underwent inguinal orchidopexy.The testicular volume,serum testosterone,AMH,and InhB levels in both groups increased markedly after surgery(all P0.05).No differences between the scrotal and inguinal groups were noted regarding the operative time(P=0.987)and amount of intraoperative bleeding(P=0.746).The overall complication rate(2.0%)of the scrotal group was slightly lower than that of the inguinal group(8.0%),although this difference was not statistically significant(P>0.05).Both scrotal and inguinal orchiopexy exerted protective effects on testicular function in children with cryptorchidism,with similar operative status and postoperative complications.Scrotal orchiopexy is an effective alternative to inguinal orchiopexy in children with cryptorchidism.

关键词： cryptorchidism orchiopexy scrotum testicular function

Conducting network interface modulated rate performance in LiFePO_(4)/C cathode materials

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Rare Metals 2022年第3期41卷 951-959页

作者： Ji-Ming Peng zhi-qiang chen Yu Li Si-Jiang Hu Qi-Chang Pan Feng-Hua Zheng Hong-qiang Wang Qing-Yu Li Guangxi Key Laboratory of Low Carbon Energy Materials School of Chemical and Pharmaceutical SciencesGuangxi New Energy Ship Battery Engineering Technology Research CenterGuangxi Normal UniversityGuilin 541004China Hubei Key Laboratory for Processing and Application of Catalytic Materials College of Chemical EngineeringHuanggang Normal UniversityHuanggang 438000China

Carbon can play a critical role in electrode,especially for LiFePO_(4)cathode,not only serving as con-tinuous conducting network for electron pathway,but also boosting Li^(+) diffusion through providing sufficient elec-trons.Here,we report the modulation of electrode/elec-trolyte interface to yield excellent rate performance by creating cross-linked conducting carbon network in LiFePO_(4)/C cathode material.Such conducting networks inhibit agglomeration and growth of LiFePO_(4)/C primary particles and hence lead to a short Li^(+)diffusion pathway.Furthermore,it also offers fast electron transmission rate and efficient electron for Li storage in the LiFePO_(4)sheath.The LiFePO_(4)/C with carbon nanotubes(CNTs)delivers a discharge capacity of 150.9 mAh·g^(-1) at 0.1C(initial Coulombic efficiency of 96.4%)and an enhanced rate capability(97.2 mAh·g^(-1) at 20.0C).Importantly,it exhi-bits a high cycle stability with a capacity retention of 90.3%even after 800 cycles at 5.0C(0.85 A·g^(-1)).This proposed interface design can be applied to a variety of battery electrodes that face challenges in electrical contact and ion transport.

关键词： Lithium-ion battery Cathode material LiFePO_(4) Rate performance

Recent progress in nuclear data measurement for ADS at IMP

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Nuclear Science and Techniques 2017年第12期28卷 269-278页

作者： zhi-qiang chen Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China

Recent progress in nuclear data measurement for ADS at Institute of Modern Physics is reviewed briefly.Based on the cooler storage ring of the Heavy Ion Research Facility in Lanzhou, nuclear data terminal was established.The nuclear data measurement facility for the ADS spallation target has been constructed, which provides a very important platform for the experimental measurements of spallation reactions. A number of experiments have been conducted in the nuclear data terminal. A Neutron Time-of-Flight(NTOF)spectrometer was developed for the study of neutron production from spallation reactions related to the ADS project.The experiments of 400 MeV/u ^(16)O bombarded on a tungsten target were presented using a NTOF spectrometer.Neutron yields for 250 MeV protons incident on a thick grain-made tungsten target and a thick solid lead target have been measured using the water-bath neutron activation method. Spallation residual productions were studied by bombarding W and Pb targets with a 250 MeV proton beam using the neutron activation method. Benchmarking of evaluated nuclear data libraries was performed for D-T neutrons on ADS relevant materials by using the benchmark experimental facility at the China Institute of Atomic Energy.

关键词： Accelerator-driven systems Nuclear data measurement Neutron Time-of-Flight spectrometer Integral experiment Evaluated nuclear data

A rare type of choledochal cysts of Todani type IV-B with typical pancreaticobiliary maljunction

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Hepatobiliary & Pancreatic Diseases International 2021年第6期20卷 582-584页

作者： Xu-Ting zhi Bing-Ran Yu zhi-qiang chen Department of Hepatobiliary Surgery General SurgeryQilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012China

Choledochal cysts(CCs),first described by Vater and Ezler in 1723,are rare congenital cystic dilations of biliary tract[1].The most widely adopted classification system from Todani et al.divides CCs into five major types and several subtypes[2].Almost all of the CCs are type I and type IV-A,while type IV-B is extremely rare[3,4].The accurate diagnosis and precise categorization of CCs are crucial for surgeons to perform proper operative strategy.

关键词： rare precise Toda

A curve-based material recognition method in MeV dual-energy X-ray imaging system

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Nuclear Science and Techniques 2016年第1期27卷 13-20页

作者： zhi-qiang chen Tiao Zhao Liang Li Department of Engineering Physics Tsinghua University Key Laboratory of Particle and Radiation Imaging (TsinghuaUniversity) Ministry of Education

High-energy dual-energy X-ray digital radiography imaging is mainly used in the material recognition of cargo inspection. We introduce the development history and principle of the technology and describe the data process flow of our system. The system corrects original data to get a dual-energy transparence image. Material categories of all points in the image are identified by the classification curve,which is related to the X-ray energy spectrum. For the calibration of classification curve, our strategy involves a basic curve calibration and a real-time correction devoted to enhancing the classification accuracy. Image segmentation and denoising methods are applied to smooth the image. The image contains more information after colorization. Some results show that our methods achieve the desired effect.

关键词： X射线成像系统校准曲线材料识别识别方法数据处理流程透明图像分类精度实时校正

Xiangbinfang granules enhance gastric antrum motility via intramuscular interstitial cells of Cajal in mice

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World Journal of Gastroenterology 2021年第7期27卷 576-591页

作者： Qi-cheng chen zhi Jiang Jun-Hong Zhang Li-Xing Cao zhi-qiang chen The Research Team of TCM Applications of Perioperative The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Research Public Service Center The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Interdigestive migrating motor complexes(MMC)produce periodic contractions in the gastrointestinal tract,but the exact mechanism of action still remains unclear.Intramuscular interstitial cells of Cajal(ICC-IM)participate in gastrointestinal hormone and neuromodulation,but the correlation between ICCIM and MMC is also unclear.We found that xiangbinfang granules(XBF)mediated the phase III contraction of MMC.Here,the effects of XBF on gastric antrum motility in W/Wv mice and the effects of ICC-IM on gastric antrum MMC are reported.AIM To observe the effects of ICC-IM on gastric antrum motility and to establish the mechanism of XBF in promoting gastric antrum motility.METHODS The density of c-kit-positive ICC myenteric plexus(ICC-MP)and ICC-IM in the antral muscularis of W/Wv and wild-type(WT)mice was examined by confocal microscopy.The effects of XBF on gastric antrum slow waves in W/Wv and WT mice were recorded by intracellular amplification recording.Micro-strain-gauge force transducers were implanted into the gastric antrum to monitor the MMC and the effect of XBF on gastric antrum motility in conscious W/Wv and WT mice.RESULTS In the gastric antrum of W/Wv mice,c-kit immunoreactivity was significantly reduced,and no ICC-IM network was observed.Spontaneous rhythmic slow waves also appeared in the antrum of W/Wv mice,but the amplitude of the antrum slow wave decreased significantly in W/Wv mice(22.62±2.23 mV vs 2.92±0.52 mV,P<0.0001).MMCs were found in 7 of the 8 WT mice but no complete MMC cycle was found in W/Wv mice.The contractile frequency and amplitude index of the gastric antrum were significantly increased in conscious WT compared to W/Wv mice(frequency,3.53±0.18 cpm vs 1.28±0.12 cpm;amplitude index,23014.26±1798.65 mV·20 min vs 3782.16±407.13 mV·20 min;P<0.0001).XBF depolarized smooth muscle cells of the gastric antrum in WT and W/Wv mice in a dose-dependent manner.Similarly,the gastric antrum motility in WT mice was significantly increased after treatment with XBF 5 mg(P<0.05).Atropine(0.1 mg

关键词： Interstitial cells of Cajal Migrating motor complex W/Wv Gastric antrum motility Xiangbinfang granules Chinese medicine

Efficacy and Safety of Aspirin for Prevention of Hepatocellular Carcinoma:An Updated Meta-analysis

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Journal of Clinical and Translational Hepatology 2022年第5期10卷 835-846页

作者： Lun-Jie Yan Sheng-Yu Yao Hai-Chao Li Guang-Xiao Meng Kai-Xuan Liu Zi-Niu Ding Jian-Guo Hong zhi-qiang chen Zhao-Ru Dong Tao Li Department of General Surgery Qilu HospitalShandong UniversityJinanShandongChina Department of Hepatobiliary Surgery The second Hospital of Shandong UniversityJinanShandongChina

Background and Aims:Previous meta-analyses have shown that aspirin use may reduce the risk of hepatocellular carcinoma(HCC).However,the optimal dose,frequency,and duration of aspirin use or the safety and efficacy of aspirin in target populations for HCC prevention remain unclear.The study aim was to investigate the efficacy and safety of aspirin for prevention of HCC.Methods:Publications were retrieved by a comprehensive literature research of several databases.Based on a random-effects model,hazard ratios(HRs)and the corresponding 95%confidence intervals(CIs)were used to assess the pooled risk.The dose-response relationship between aspirin use and HCC risk was assessed with a restricted cubic spline model.Results:Twenty-two studies were included in the metaanalysis.Aspirin use was associated with a reduced risk of HCC(HR=0.64,95%CI:0.56–0.75).The effect was robust across sex and age;however,women and the non-elderly had the greatest benefit from aspirin use.The preventive effect was well reproduced in those with comorbidities.Daily use and long-term use of aspirin appeared to offer greater benefits.Aspirin 100 mg/d was associated with maximum reduction of HCC risk.Aspirin use did slightly increase the risk of bleeding(HR=1.14,95%CI:1.02–1.27).Conclusions:Our meta-analysis confirmed that use of aspirin significantly reduced the incident risk of HCC.Regular and long-term aspirin use offers a greater advantage.Aspirin use was associated with an increased risk of bleeding.We recommend 100 mg/d aspirin as a feasible dose for further research on primary prevention of HCC in a broad at-risk population.

关键词： Aspirin Hepatocellular carcinoma Prevention Meta-analysis Doseresponse analysis

Effects of Chinese herbal medicine Xiangbin prescription on gastrointestinal motility

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World Journal of Gastroenterology 2017年第16期23卷 2987-2994页

作者： zhi Jiang Li-Xing Cao Bo Liu Qi-cheng chen Wen-Fan Shang Lu Zhou Dan-Yan Li De-An Guo zhi-qiang chen Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510120Guangdong ProvinceChina Institute of Basic Medical Sciences Chinese Academy of Medical SciencesBeijing 100005China Shanghai Research Center for Modernization of Traditional Chinese Medicine Shanghai Institute of Materia MedicaShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 201203China

AIM To investigate the effects of Xiangbin prescription(XBP), a Chinese herbal concoction, on gastrointestinal motility.METHODS Forty healthy volunteers were recruited for this randomized controlled trial of XBP. Antroduodenojejunal manometry was used to monitor gastrointestinal motility in these subjects. After the subjects had fasted for at least 12 h, XBP(n = 30) or placebo(n = 10) was orally administrated and gastrointestinal motility was recorded for 4 h. Plasma motilin and ghrelin were measured by enzyme-linked immunosorbent assay.RESULTS Oral administration of XBP significantly increased the amplitude of duodenal contractions [19.5(13.0-26.7) vs 16.9(12.3-23.9), P < 0.05], jejunal contractions [18.3(15.3-25.0) vs 15.4(11.7-23.9), P < 0.01], and the motility index of duodenal contractions [522.0(146.0-139.0) vs 281.0(76.5-1006.0), P < 0.01] in phase Ⅱ of the migratory motor complex(MMC), which subsequently initiated the MMC cycle [74.0(30.0-118.0) vs 116.5(24.0-219.0), P < 0.05], shortened the duration of phase I of the MMC [42.0(0.0-90.0) vs 111.5(42.0-171.0), P < 0.01], and lengthened the duration of phase Ⅱ of the MMC [120(21-240) vs 58(16-170), P < 0.01] compared to the duration before XBP administration. There were significant differences in the amplitude of jejunal contractions [19.8(14.0-30.0) vs 18.0(13.0-28.5), P < 0.05], the motility index of duodenal contractions [236.0(115.0-306.0) vs 195.0(109.0-310.0), P < 0.05], and jejunal contractions [214.0(95.0-403.0) vs 178.0(55.0-304.0), P < 0.01] in phase Ⅲ of the MMC. Oral administration of XBP greatly increased plasma motilin(57.69 ± 9.03 vs 49.38 ± 8.63, P < 0.01) and ghrelin(279.20 ± 104.31 vs 238.73 ± 115.59, P < 0.01) concentrations compared to concentrations after oral administration of the placebo.CONCLUSION XBP can stimulate duodenal and jejunal motility and increase the concentrations of plasma motilin and ghrelin. The clinical applicability of XBP in treating GDIM deserves investigation.

关键词： Antrotroduodenojejunal manometry Gastrointestinal motility Migrating motor complex Xiangbin concoction Motilin Ghrelin

INVERSE OPALINE STRUCTURE TITANIA PHOTONIC CRYSTALS BY FUNCTIONALLY MODIFIED COLLOIDAL CRYSTALS TEMPLATING

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Chinese Journal of Polymer Science 2007年第2期25卷 217-220页

作者： Hong-yu Li zhi-qiang chen Hai-qiao Wang Bo Meng Xiao-yu Li Department of Chemistry Anyang Teachers College Anyang Henan 455000 China The Key Laboratory of Nanomaterials of Ministry of Education College of Materials Science and Engineering Beijing University of Chemical Technology Beijing 100029 China

Ordered macroporous titania photonic crystals （PCs） and photonic balls were fabricated by functional modified polymer colloidal crystals. The TiO2 PCs and balls formed through this method exhibit no cracks and lacun... 详细信息

关键词： Photonic crystals Photonic balls Ordered macroporous titania Polymer colloidal crystals.