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Does a low solar cycle minimum hint at a weak upcoming cycle?

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Research in Astronomy and Astrophysics 2010年第10期10卷 950-955页

作者： zhan-le du hua-ning wang Key Laboratory of Solar Activity National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

The maximum amplitude （Rm） of a solar cycle, in the term of mean sunspot numbers, is well-known to be positively correlated with the preceding minimum （Rmin）. So far as the long term trend is concerned, a low level of Rmin tends to be followed by a weak Rm, and vice versa. We found that the evidence is insufficient to infer a very weak Cycle 24 from the very low Rmin in the preceding cycle. This is concluded by analyzing the correlation in the temporal variations of parameters for two successive cycles.

关键词： Sun activity -- Sun general -- sunspots

A Running Average Method for Predicting the Size and length of a Solar Cycle

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Chinese Journal of Astronomy and Astrophysics 2008年第4期8卷 477-488页

作者： zhan-le du hua-ning wang Li-Yun zhang National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

The running correlation coefficient between the solar cycle amplitudes and the max-max cycle lengths at a given cycle lag is found to vary roughly in a cyclical wave with the cycle number, based on the smoothed monthly mean Group sunspot numbers available since 1610. A running average method is proposed to predict the size and length of a solar cycle by the use of the varying trend of the coefficients. It is found that, when a condition （that the correlation becomes stronger） is satisfied, the mean prediction error （16.1） is much smaller than when the condition is not satisfied （38.7）. This result can be explained by the fact that the prediction must fall on the regression line and increase the strength of the correlation. The method itself can also indicate whether the prediction is reasonable or not. To obtain a reasonable prediction, it is more important to search for a running correlation coefficient whose varying trend satisfies the proposed condition, and the result does not depend so much on the size of the correlation coefficient. As an application, the peak sunspot number of cycle 24 is estimated as 140.4 ± 15.7, and the peak as May 2012 ±11 months.

关键词： Sun activity -- Sun sunspots - Sun general

The relationships of solar flares with both sunspot and geomagnetic activity

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Research in Astronomy and Astrophysics 2012年第4期12卷 400-410页

作者： zhan-le du hua-ning wang Key Laboratory of Solar Activity National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100012China

The relationships between solar flare parameters （total importance, time duration, flare index, and flux） and sunspot activity （R z ） as well as those between geomagnetic activity （aa index） and the flare parameters can be well described by an integral response model with the response time scales of about 8 and 13 months, respectively. Compared with linear relationships, the correlation coefficients of the flare parameters with R z , of aa with the flare parameters, and of aa with R z based on this model have increased about 6%, 17%, and 47% on average, respectively. The time delays between the flare parameters with respect to R z , aa to the flare parameters, and aa to R z at their peaks in a solar cycle can be predicted in part by this model （82%, 47%, and 78%, respectively）. These results may be further improved when using a cosine filter with a wider window. It implies that solar flares are related to the accumulation of solar magnetic energy in the past through a time decay factor. The above results may help us to understand the mechanism of solar flares and to improve the prediction of the solar flares.

关键词： Sun: activity -- Sun: sunspots -- Sun: flares -- geomagnetic activity

The Relation between the Amplitude and the Period of Solar Cycles

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Chinese Journal of Astronomy and Astrophysics 2006年第4期6卷 489-494页

作者： zhan-le du hua-ning wang Xiang-Tao He National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 Department of Astronomy Beijing Normal University Beijing 100875

The maximum amplitudes of solar activity cycles are found to be well anticorrelated （r = -0.72） with the newly defined solar cycle lengths three cycles before （at lag -3） in 13-month running mean sunspot numbers during the past 190 years. This result could be used for predicting the maximum sunspot numbers. The amplitudes of Cycles 24 and 25 are estimated to be 149.5±27.6 and 144.3±27.6, respectively.

关键词： Sun: activity -- Sun: sunspots -- Sun: general

The pivotal role of microglia in injury and the prognosis of subarachnoid hemorrhage

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Neural Regeneration Research 2025年第7期20卷 1829-1848页

作者： Wenjing ning Shi Lv Qian wang Yuzhen Xu Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina Department of Central Laboratory The Affiliated Taian City Central Hospital of Qingdao UniversityTaianShandong ProvinceChina

Subarachnoid hemorrhage leads to a series of pathological changes,including vascular spasm,cellular apoptosis,blood–brain barrier damage,cerebral edema,and white matter ***,which are the key immune cells in the central nervous system,maintain homeostasis in the neural environment,support neurons,mediate apoptosis,participate in immune regulation,and have neuroprotective *** evidence has shown that microglia play a pivotal role in the pathogenesis of subarachnoid hemorrhage and affect the process of injury and the prognosis of subarachnoid ***,microglia play certain neuroprotective roles in the recovery phase of subarachnoid *** approaches aimed at modulating microglia function are believed to attenuate subarachnoid hemorrhage *** provides new targets and ideas for the treatment of subarachnoid ***,an in-depth and comprehensive summary of the role of microglia after subarachnoid hemorrhage is still *** review describes the activation of microglia after subarachnoid hemorrhage and their roles in the pathological processes of vasospasm,neuroinflammation,neuronal apoptosis,blood–brain barrier disruption,cerebral edema,and cerebral white matter *** also discusses the neuroprotective roles of microglia during recovery from subarachnoid hemorrhage and therapeutic advances aimed at modulating microglial function after subarachnoid ***,microglia in subarachnoid hemorrhage are targeted with TLR inhibitors,nuclear factor-κB and STAT3 pathway inhibitors,glycine/tyrosine kinases,NLRP3 signaling pathway inhibitors,Gasdermin D inhibitors,vincristine receptorαreceptor agonists,ferroptosis inhibitors,genetic modification techniques,stem cell therapies,and traditional Chinese ***,most of these are still being evaluated at the laboratory *** clinical studies and data on subarachnoid hemorrhage are required to improve the treatment of subarachnoid hemor

关键词： apoptosis blood–brain barrier brain edema microglia neuroinflammation neuron neuroprotection subarachnoid hemorrhage vasoconstriction white matter injury

Pyroptosis,ferroptosis,and autophagy in spinal cord injury:regulatory mechanisms and therapeutic targets

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Neural Regeneration Research 2025年第10期20卷 2787-2806页

作者： Qingcong Zheng du wang Rongjie Lin Weihong Xu Department of Spinal Surgery the First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Arthritis Clinical and Research Center Peking University People’s HospitalBeijingChina Department of Orthopedic Surgery Fujian Medical University Union HospitalFuzhouFujian ProvinceChina

Regulated cell death is a form of cell death that is actively controlled by *** studies have shown that regulated cell death plays a key role after spinal cord *** and ferroptosis are newly discovered types of regulated cell deaths that have been shown to exacerbate inflammation and lead to cell death in damaged spinal ***,a complex form of cell death that is interconnected with various regulated cell death mechanisms,has garnered significant attention in the study of spinal cord *** injury triggers not only cell death but also cellular survival *** signaling pathways play pivotal roles in influencing the processes of both deterioration and repair in spinal cord injury by regulating pyroptosis,ferroptosis,and ***,this review aims to comprehensively examine the mechanisms underlying regulated cell deaths,the signaling pathways that modulate these mechanisms,and the potential therapeutic targets for spinal cord *** analysis suggests that targeting the common regulatory signaling pathways of different regulated cell deaths could be a promising strategy to promote cell survival and enhance the repair of spinal cord ***,a holistic approach that incorporates multiple regulated cell deaths and their regulatory pathways presents a promising multi-target therapeutic strategy for the management of spinal cord injury.

关键词： autophagy cell death ferroptosis inflammation pathological mechanisms pyroptosis regulated cell death regulatory pathways spinal cord injury therapeutic targets

A New Method to Determine Epochs of Solar Cycle Extrema

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Chinese Journal of Astronomy and Astrophysics 2006年第3期6卷 338-344页

作者： zhan-Lc du hua-ning wang Xiang-Tao He Department of Astronomy Beijing Normal University Beijing 100875 National Astronomical Observatories Chinese Academy of Sciences Beijing 100012

A weighted average method is proposed to determine the epochs of solar cycle extrema and hence the solar cycle lengths. Comparing to the previous methods, this method has the advantage that the extremum epochs are eas... 详细信息

关键词： Sun: activity - Sun: sunspots - Sun:general

Support Vector Machine combined with K-Nearest Neighbors for Solar Flare Forecasting

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Chinese Journal of Astronomy and Astrophysics 2007年第3期7卷 441-447页

作者： Rong Li hua-ning wang Han He Yan-Mei Cui zhan-le du National Astronomical Observatories Chinese Academy of Sciences Beijing 100012

A method combining the support vector machine （SVM） the K-Nearest Neighbors （KNN）, labelled the SVM-KNN method, is used to construct a solar flare forecasting model. Based on a proven relationship between SVM and KNN, the SVM-KNN method improves the SVM algorithm of classification by taking advantage of the KNN algorithm according to the distribution of test samples in a feature space. In our flare forecast study, sunspots and 10cm radio flux data observed during Solar Cycle 23 are taken as predictors, and whether an M class flare will occur for each active region within two days will be predicted. The SVM- KNN method is compared with the SVM and Neural networks-based method. The test results indicate that the rate of correct predictions from the SVM-KNN method is higher than that from the other two methods. This method shows promise as a practicable future forecasting model.

关键词： Sun flare - Sun sunspot - Sun activity - Sun magnetic fields

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu Zhao Juan-Han Yu Yi-hua wang Yi-Xin Liu Lu Xu Lin Fu ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report