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Intimal pericytes as the second line of immune defence in atherosclerosis

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World Journal of Cardiology 2015年第10期7卷 583-593页

作者： Ekaterina A Ivanova yuri v Bobryshev Alexander N Orekhov Department of Development and Regeneration Biomedical Sciences Group KU LeuveLeuvenBelgium Faculty of Medicine School of Medical Sciences University of New South Wales School of Medicine University of Western Sydney Laboratory of Angiopathology Institute of General Pathology and Pathophysiology Russian Academy of Sciences Institute for Atherosclerosis Research Skolkovo Innovative Center Department of Biophysics Faculty of Biology Lomonosov Moscow State University

Inflammation plays an essential role in the development of atherosclerosis. The initiation and growth of atherosclerotic plaques is accompanied by recruitment of inflammatory and precursor cells from the bloodstream and their differentiation towards pro-inflammatory phenotypes. This process is orchestrated by the production of a number of pro-inflammatory cytokines and chemokines. Human arterial intima consists of structurally distinct leaflets, with a proteoglycan-rich layer lying immediately below the endothelial lining. Recent studies reveal the important role of stellate pericyte-like cells(intimal pericytes) populating the proteoglycan-rich layer in the development of atherosclerosis. During the pathologic process, intimal pericytes may participate in the recruitment of inflammatory cells by producing signalling molecules and play a role in the antigen presentation. Intimal pericytes are also involved in lipid accumulation and the formation of foam cells. This review focuses on the role of pericytelike cells in the development of atherosclerotic lesions.

关键词： Atherosclerosis Arteries Intima Immune-inflammator

The Impact of Agricultural Import Tariff on Economic Growth： Evidence From Mercosur Countries

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Chinese Business Review 2014年第3期13卷 137-153页

作者： yuri N. Moseykin Irina v. Levchenko Peoples' Friendship University of Russia Moscow Russian Federation

This research paper attempts to determine the relationship between agricultural import tariff and economic growth of Mercosur countries over the period 1996-2007 using regression analysis as well as evaluates the gains and losses from the group＇s trade policy over the same period. The introductory part of this paper focuses on the dynamics of changes in economic growth, trade, and import tariff of these countries over the last two decades. The results of the performed regression analysis of panel data suggest that trade liberalization has a quantitatively significant positive effect on growth. By using the coefficient estimates on tariff, the authors perform a quantitative evaluation of gains and losses from trade policy, for which tariff measures to trade （imports） are used as a proxy.

关键词： Mercosur economic growth trade import tariff panel data regression

Correlation between surface charge and hydration on mineral surfaces in aqueous solutions: A critical review

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International Journal of Minerals,Metallurgy and Materials 2020年第7期27卷 857-871页

作者： Hong-liang Li Wen-nan Xu Fei-fei Jia Jian-bo Li Shao-xian Song yuri Nahmad College of Mining Engineering Taiyuan University of TechnologyTaiyuan 030024China Department of Chemical and Materials Engineering University of AlbertaEdmontonAlberta T6G2V4Canada School of Resources and Environmental Engineering Wuhan University of TechnologyWuhan 430070China Instituto de Fiscia Universidad Autonoma de San Luis PotosiAv.Sierra LeonaSan Luis Potosi 78000Mexico

Surface charges and hydration are predominant properties of colloidal particles that govern colloidal stability in aqueous *** properties usually coexist and interact with each *** correlation between the surface charge and hydration of minerals is summarized on the basis of innovative experimental,theoretical,and molecular dynamics simulation *** factors affecting the adsorption behavior of ions and water molecules,such as ion concentration,ion hydration radius and valence,and surface properties,are *** example,the hydration and adsorption states completely differ between monovalent and divalent *** ions of the same valence,the effect of surface charge on the hydration force follows the Hofmeister adsorption *** concentration exerts a significant effect on the hydration force at high ion ***,the ion correlations in high-concentration electrolyte systems become long *** interfacial water structure largely depends on surface *** hydration layer between different surfaces shows large qualitative differences.

关键词： surface hydration surface charged ion mineral water molecule

Risk factors associated with Barrett's epithelial dysplasia

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World Journal of Gastroenterology 2014年第15期20卷 4353-4361页

作者： Mikiko Fujita yuri Nakamura Saeko Kasashima Maiko Furukawa Ryoichi Misaka Hikaru Nagahara Department of Gastroenterology Aoyama HospitalTokyo Women’s Medical University

AIM: To elucidate risk factors associated with dysplasia of short-segment Barrett’s esophagus (BE).

关键词： Barrett’ s esophagus, Dysplasia, Helicobacter pylori, p53, Risk factors

Myxomycete diversity in the Tarim basin and eastern Tian-Shan,Xinjiang Prov.,China

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Fungal Diversity 2013年第2期59卷 91-108页

作者： Martin Schnittler yuri K.Novozhilov Eva Carvajal Frederick W.Spiegel Institute of Botany and Landscape Ecology Ernst Moritz Arndt University GreifswaldGrimmer Str.8817487 GreifswaldGermany v.L.Komarov Botanical Institute of the Russian Academy of Sciences Prof.Popov St.2197376 St.PetersburgRussia Royal Botanic Garden(CSIC) Plaza de Murillo2Madrid 28014Spain Department of Biological Sciences University of ArkansasSCEN 6011FayettevilleAR 72701USA

We report the results of a survey for myxomycetes in the Chinese province of Xinjiang,covering the northern part of the Tarim basin and the eastern Tian-Shan *** in the hyperarid Tarim basin focused on monospecific Tugai forests;these are park-like stands of the phreatophyte Populus *** a transect from the Tarim basin to the mountains,trees vanish outside the basin,but reoccur at ca.1,400 m elevation as monospecific forests of Picea schrenkiana;the second focal area of the *** a total of 362 substrate samples(245 from the Tarim basin,177 from the mountains)we obtained 477 determinable records of myxomycetes,plus a total of 206 field collections,the latter almost exclusively from the spruce forests in the *** the 80 taxa recorded 53 are represented by field collections,and 32 were found in moist chamber cultures;with a very low overlap in species assemblages found in the field and in *** receiving less than 50 mm annual precipitation,corticolous myxomycetes were common in the Tugai forests,with Physarum pseudonotabile ***.,Didymium anellus,Echinostelium colliculosum and Protophysarum phloiogenum as the most common *** to the Tarim basin(21 taxa)the mountains were much richer in myxomycetes(75 taxa),although the diversity recovered from cultures was comparable(21 vs.28 taxa).Most species from the mountains fruited on decaying spruce,often collected under or even inside the logs due to the extremely dry *** results suggest first that there is no lower limit of annual precipitation for myxomycetes,as long as at least some days with nightly dew fall allow these organisms to complete their life ***,the two examples of surprisingly diverse myxomycete assemblages from monospecific forests demonstrate,that species richness of this group is not necessarily connected with plant diversity of the *** survey is the most eastern of a large-scale study of myxomycete diversity throughout M

关键词： Amoebozoa Distribution Moist chamber culture Myxogastria Plasmodial slime molds

Mitochondrial dysfunction and mitochondrial DNA mutations in atherosclerotic complications in diabetes

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World Journal of Cardiology 2012年第5期4卷 148-156页

作者： Dimitry A Chistiakov Igor A Sobenin yuri v Bobryshev Alexander N Orekhov Department of Medical Nanobiotechnology Pirogov Russian State Medical University117997 MoscowRussia Institute for Atherosclerosis Research Skolkovo Innovative Centre121609 MoscowRussia Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences125315 MoscowRussia Russian Cardiology Research and Production Complex 121552 MoscowRussia Faculty of Medicine School of Medical SciencesUniversity of New South WalesNSW 2052SydneyAustralia

Mitochondrial DNA(mtDNA) is particularly prone to oxidation due to the lack of histones and a deficient mismatch repair *** explains an increased mutation rate of mtDNA that results in heteroplasmy,e.g.,the coexistence of the mutant and wild-type mtDNA molecules within the same *** diabetes mellitus,glycotoxicity,advanced oxidative stress,collagen cross-linking,and accumulation of lipid peroxides in foam macrophage cells and arterial wall cells may significantly decrease the mutation threshold required for mitochondrial dysfunction,which in turn further contributes to the oxidative damage of the diabetic vascular wall,endothelial dysfunc-tion,and atherosclerosis.

关键词： Mitochondrial DNA Mutation Heteroplasmy Atherosclerosis Diabetes Oxidative stress Ultrastructure

Impact of severe plastic deformation on kinetics and thermodynamics of hydrogen storage in magnesium and its alloys

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Journal of Materials Science & Technology 2023年第15期146卷 221-239页

作者： Kaveh Edalati Etsuo Akiba Walter J.Botta yuri Estrin Ricardo Floriano Daniel Fruchart Thierry Grosdidier Zenji Horita Jacques Huot Hai-Wen Li Huai-Jun Lin Ádám Révész Michael J.Zehetbauer WPI International Institute for Carbon-Neutral Energy Research(WPI-I2CNER)Kyushu UniversityFukuokaJapan International Research Center for Hydrogen Energy Kyushu UniversityFukuokaJapan Departamento de Engenharia de Materiais Universidade Federal de São CarlosSao Carlos-SPBrazil Department of Materials Science and Engineering Monash UniversityClaytonVIC 3800Australia Department of Mechanical Engineering the University of Western AustraliaCrawleyWA 6009Australia School of Applied Sciences University of Campinas(UNICAMP)LimeiraSão PauloBrazil Institut Néel CNRS&UGA38042 GrenobleFrance JOMI-LEMAN SA 74890 FessyFrance Universitéde Lorraine Laboratory of Excellence on Design of Alloy Metals for low-mass Structures(DAMAS)MetzF-57070France Universitéde Lorraine Laboratoire d’Etude des Microstructures et de Mécanique des Matériaux(LEM3 UMR 7239)MetzF-57070France Graduate School of Engineering Kyushu Institute of TechnologyKitakyushuJapan Magnesium Research Center Kumamoto UniversityKumamotoJapan Synchrotron Light Application Center Saga UniversitySagaJapan Hydrogen Research Institute Universitédu QuébecàTrois-Rivières3351 des ForgesTrois-RivièresQC G9A 5H7Canada Hefei General Machinery Research Institute Hefei 230031China Institute of Advanced Wear&Corrosion Resistance and Functional Materials Jinan UniversityGuangzhou 510632China Department of Materials Physics Eötvös UniversityBudapestH-1518P.O.B.32BudapestHungary Faculty of Physics University of ViennaBoltzmanngasse 5A-1090 WienAustria

Magnesium and its alloys are the most investigated materials for solid-state hydrogen storage in the form of metal hydrides,but there are still unresolved problems with the kinetics and thermodynamics of hydrogenation and dehydrogenation of this group of *** plastic deformation(SPD)methods,such as equal-channel angular pressing(ECAP),high-pressure torsion(HPT),intensive rolling,and fast forging,have been widely used to enhance the activation,air resistance,and hydrogenation/dehydrogenation kinetics of Mg-based hydrogen storage materials by introducing ultrafine/nanoscale grains and crystal lattice *** severely deformed materials,particularly in the presence of alloying additives or second-phase nanoparticles,can show not only fast hydrogen absorption/desorption kinetics but also good cycling *** was shown that some materials that are apparently inert to hydrogen can absorb hydrogen after SPD ***,the SPD methods were effectively used for hydrogen binding-energy engineering and synthesizing new magnesium alloys with low thermodynamic stability for reversible low/room-temperature hydrogen storage,such as nanoglasses,high-entropy alloys,and metastable phases including the high-pressureγ-MgH2 *** work reviews recent advances in the development of Mg-based hydrogen storage materials by SPD processing and discusses their potential in future applications.

关键词： Severe plastic deformation(SPD) Nanostructured materials Ultrafine-grained(UFG)materials Magnesium hydride(MgH_(2)) Magnesium-based alloys Hydrogen absorption Hydrogenation kinetics Hydrogen storage thermodynamics

Multiscale wood micromechanics and size effects study via nanoindentation

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Journal of Bioresources and Bioproducts 2023年第3期8卷 246-264页

作者： yuri I.Golovin Alexander A.Gusev Dmitry Yu.Golovin Sergey M.Matveev Alexander I.Tyrin Alexander A.Samodurov viktor v.Korenkov Inna A.vasyukova Maria A.Yunack Institute“Nanotechnology and Nanomaterials” G.R.Derzhavin Tambov State University392000 TambovRussia Department of Chemical Enzymology School of ChemistryLomonosov Moscow State University119991 MoscowRussia Research and Educational Center«Sustainable Development of the Forest Complex» Voronezh State Forestry University Named after G.F.Morozov394087 VoronezhRussia Department of Functional Nanosystems and High-Temperature Materials National University of Science and Technology“MISIS”119991 MoscowRussia

Wood as a material is a natural composite with a complex hierarchically arranged *** scale levels of wood structure contribute to its macroscopic mechanical *** nature of such characteristics and deformation modes differs radically at different scale *** macroscopic properties are well studied,and the relevant information can be easily found in the ***,the knowledge of the deformation mechanisms at the mesoscopic level corresponding to the cellular structure of early and late wood layers of annual growth rings is *** hinders building the comprehensive multiscale model of how wood mechanical properties are *** paper described the results of scanning of mechanical properties of softwood and hardwood samples,such as common pine,small-leaf lime,and pedunculate oak,by means of nanoindentation(NI).The NI technique allows varying the size of deformed region within a wide range by altering maximal load(P max)applied to the indenter so that one can re-peatedly and non-destructively test wood structural components at different scale levels on the same sample without changing the technique or *** was discovered that the effective microhardness(H eff)and Young’s modulus(E eff)decreased manifold with P max growing from 0.2 to 2000 *** drop in H effwas observed when the locally deformed region grew,and re-sulting from P max increase generally follows the rule similar to the Hall-Petch relation for yield stress,strength,and hardness initially established for metals and alloys,though obviously in those cases the underlying internal mechanisms are quite *** nature and micromechanisms of such size effect(SE)in wood revealed using NI were discussed in this *** P maxvich indenter was much smaller than the cell wall ***,in this case,NI measured the internal mechanical properties of the cell wall material as long as free boundaries impact

关键词： Nano/microhardness Scanning nanoindentation Annual growth ring Early and late wood Dendrochronology

Sectoral Advanced Planning Systems (APS) Based on Utility Functions

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Journal of Management Science & Engineering Research 2023年第2期6卷 32-46页

作者： yuri Mauergauz Russian MES-Center Moscow119296Russian Federation

This paper contains the example of sectoral APS systems,for which the problem algorithmic space coincides with the relevant operational environment with great *** method of scheduling for technological processes with looping is described,based on the simultaneous application of two criteria:the value of relative direct costs and the average utility of order *** influence of buffers on the work of shops is *** proposed method provides an automatic grouping of the same type of jobs on all machines involved while taking into account the required duration of jobs.A package of application programs has been developed that allows planning for an average number of *** result of the program is a set of non-dominant(not improved)options that are offered to the user for making a final decision.

关键词： Scheduling Production intensity Buffer Job shop