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External defects and severity level evaluation of potato using single and multispectral imaging in near infrared region Author links open overlay panel

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Information Processing in Agriculture 2024年第1期11卷 80-90页

作者： Dimas Firmanda Al Riza Slamet Widodo Kazuya yamamoto Kazunori Ninomiya Tetsuhito Suzuki yuichi Ogawa Naoshi Kondo Laboratory of Biosensing Engineering Graduate School of AgricultureKyoto UniversityKitashirakawaKyoto 6068267Japan Department of Biosystems Engineering Faculty of Agricultural TechnologyUniversitas BrawijayaJl.VeteranMalang 65145Indonesia Department of Mechanical and Biosystem Engineering Bogor Agricultural UniversityJl.Raya Darmaga Kampus IPB DarmagaBogor 16680Indonesia Technology Development Department Shibuya Seiki Co.Ltd.66Takaoka-choMatsuyamaEhime 7918036Japan

Non-invasive potato defects detection has been demanded for sorting and grading *** on the classification of the defects has been available,however,investigation on the severity level calculation is *** the detection of the common scab,it has been found that imaging in the infrared region provide an interesting characteristic that could distinguish defected area to normal ***,investigations on this wavelength range is interesting to add more knowledge and for *** this research,the multispectral image has been obtained and investigated especially at three wavelengths(950,1150,1600 nm).Image pre-processing and pseudo-color conversion techniques were explored to enhance the contrast between defects,normal background skin area and soil *** show that external defects,such as common scab and some mechanical damage types,appear brighter in the near infrared region,especially at 1600 nm against the normal skin *** has been found that pseudo-color images conversion provides more information regarding type if surface characteristics compared to grayscale single *** segmentation using pseudo-color images after multiplication operation pre-processing could be used for common scab and mechanical damage detection excluding soil deposits with a Dice Sorensen coefficient of *** addition,image segmentation using single image at 1600 nm shown relatively better results with Dice Sorensen coefficient of 0.72 with note that thick soil deposits will also be *** severity level evaluation had an R2 correlation of 0.84 against standard measurements of severity.

关键词： Multispectral imaging Pseudo-color Common scab External defects Near infrared

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COMPOSITE NATURAL ORBITAL METHOD—A TEST ON BIPYRROLH

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原子与分子物理学报 1990年第4期7卷 1580-1584页

作者： yuichi yamamoto Takeshi Noro Kimio Ohno Department of Chemistry Faculty of ScienceHokkaido UniversitySapporo060JapanDepartment of ChemistryFaculty of ScienceHokkaido UniversitySapporo060JapanDepartment of ChemistryFaculty of ScienceHokkaido UniversitySapporo060Japan

A scheme for construction of virtual orbitals for use in a configuration interaction(CI) method is described and is applied to the 2,2'-bipyrrole moecule.

关键词：量子化学自洽场分子轨道双吡咯

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A Flat Spectral Response AWG Demultiplexer Composed of Slabs with Islands and Peninsulas

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光学学报 2003年第S1期23卷 157-158页

作者： Yutaka Natsume Junji Yamauchi Ryoichi Tazawa Koji Ishikawa Shigeru Kawaguchi yuichi yamamoto Hisamatsu Nakano R & D Department NHK Spring Co. Ltd. 3-10 Fukuura Kanazawa-ku Yokohama 236-0004 Japan Faculty of Engineering Hosei University 3 -7-2 Kajino-cho Koganei Tokyo 184-8584 Japan

Phase adjustment elements called islands and peninsulas are introduced to obtain an AWG demultiplexer with a flat spectral response. Use of the peninsulas enables us to achieve a IdB bandwidth of 0.5 nm.

关键词： spectral response

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QUADRANT ANALYSIS OF BUBBLE INDUCED VELOCITY FLUCTUATIONS IN A TRANSITIONAL BOUNDARY LAYER

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Journal of Hydrodynamics 2009年第1期21卷 93-99页

作者： HUANG Jian MURAI yuichi yamamoto Fujio Graduate School of Engineering Fiber Amenity Engineering Course University of Fukui Bunkyo 3-9-1 Fukui 910-8507 Japan Division of Energy and Environment System School of Engineering Hokkaido University Sapporo Japan Graduate School of Engineering University of Fukui Bunkyo 3-9-1 Fukui 910-8507 Japan

Our previous study showed that the frictional drag decreases with increasing void fraction at Re〉1300, while it increases at Re 〈 1000. Decomposition of the Reynolds shear stress also implied that bubbles induce isotropy of turbulence. In order to confirm our previous analysis and to further investigate flow fields in the vicinity of bubbles, we analyze velocity fluctuations on the quadrant space in the streamwise and transverse directions （u′-v′ plane）. Here, we focus on two specific Reynolds numbers （at Re≈900 and ≈1410, which are close to the laminar-to-turbulent transition regime） and discuss bubble effects on sweep （u′〉 0, v′〈 0 ） and ejection （u′〈 0, v′〉 0） events as a function of the Reynolds number. We also illustrate velocity fluctuations in the vicinity of an individual bubble and a swarm of bubbles on the u′- v′ coordinates. The results show that a bubble swarm suppresses the velocity fluctuations at Re≈1410.

关键词： bubbly channel flow Particle Tracking Velocimetry (PTV) quadrant analysis velocity fluctuation boundary layer,laminar-to-turbulent transition

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Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

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Relationships of early esophageal cancer with human papillomavirus and alcohol metabolism

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World Journal of Gastroenterology 2020年第39期26卷 6047-6056页

作者： Masaki Inoue yuichi Shimizu Marin Ishikawa Satoshi Abiko Yoshihiko Shimoda Ikko Tanaka Sayoko Kinowaki Masayoshi Ono Keiko yamamoto Shoko Ono Naoya Sakamoto Department of Gastroenterology and Hepatology Graduate School of Medicine and Faculty of MedicineHokkaido UniversitySapporoHokkaido 060-0808Japan of Endoscopy Hokkaido University HospitalSapporoHokkaido 060-8648Japan Department of Cancer Pathology Hokkaido University Graduate School of MedicineSapporoHokkaido 060-0808Japan Department of Gastroenterology Hokkaido University HospitalSapporoHokkaido 060-8648Japan Department of Gastroenterology and Hepatology Hakodate Municipal HospitalHakodateHokkaido 041-8680Japan

BACKGROUND It is well known that an alcohol consumption habit together with inactive heterozygous aldehyde dehydrogenase-2(ALDH2)is an important risk factor for the development of esophageal squamous cell carcinoma(ESCC).It remains controversial whether human papillomavirus(HPV)infection contributes to the occurrence/development of *** has been no study in which the relationship between ESCC and HPV in addition to alcohol dehydrogenase-1B(ADH1B)and ALDH2 genotypes was *** To evaluate relationships between HPV infection and development of esophageal cancer,particularly early esophageal cancer,based on ADH1B/ALDH2 *** We conducted an exploratory retrospective study using new specimens,and we enrolled 145 patients who underwent endoscopic resection for superficial ESCC and had been observed for more than two years by both physical examination and endoscopic examination in Hokkaido University *** was collected to analyze genetic polymorphisms of ADH1B/*** performed in situ hybridization for resected specimens to detect HPV by using an HPV type 16/18 *** HPV was detected in 15(10.3%)of the 145 patients with ***-positive rates in inactive ALDH2*1/*2 and ALDH2*1/*1+*2/*2 were 10.8%and 9.8%,respectively(P=1.00).HPV-positive rates in slow-metabolizing ADH1B*1/*1 and ADH1B*1/*2+*2/*2 were 12.0%and 10.0%,respectively(P=0.72).HPV-positive rates in the heavy or moderate alcohol consumption group and the light or rare consumption group were 11.1%and 8.7%,respectively(P=0.68).HPV-positive rates in the heavy smoking group and the light or no smoking group were 11.8%and 8.3%,respectively(P=0.59).The 3-year incidence rates of secondary ESCC or head and neck cancer after initial treatment in the HPV-positive and HPVnegative groups were 14.4%and 21.4%(P=0.22),*** In the present situation,HPV status is considered to be less important than other risk factors,such as alcohol consumption,smoking habit,AD

关键词： Human papillomavirus Esophageal squamous cell carcinoma Early esophageal cancer Alcohol dehydrogenase-1B Aldehyde dehydrogenase-2 Endoscopic resection

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Tracing founder haplotypes of Japanese apple varieties: application in genomic prediction and genome-wide association study

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Horticulture Research 2021年第1期8卷 614-627页

作者： Mai FMinamikawa Miyuki Kunihisa Koji Noshita Shigeki Moriya Kazuyuki Abe Takeshi Hayashi yuichi Katayose Toshimi Matsumoto Chikako Nishitani Shingo Terakami Toshiya yamamoto Hiroyoshi Iwata Laboratory of Biometry and Bioinformatics Department of Agricultural and Environmental BiologyGraduate School of Agricultural and Life SciencesThe University of Tokyo1-1-1 YayoiBunkyoTokyo 113-8657Japan Institute of Fruit Tree and Tea Science National Agriculture and Food Research Organization(NARO)2-1 FujimotoTsukubaIbaraki 305-8605Japan Division of Apple Research Institute of Fruit Tree and Tea ScienceNARO92-24 Shimokuriyagawa NabeyashikiMoriokaIwate 020-0123Japan Institute of Crop Science NARO2-1-2 KannondaiTsukubaIbaraki 305-8518Japan Institute of Agrobiological Sciences NARO1-2 OwashiTsukubaIbaraki 305-8634Japan

Haplotypes provide useful information for genomics-based approaches,genomic prediction,and genome-wide association *** a small number of superior founders have contributed largely to the breeding history of fruit trees,the information of founder haplotypes may be relevant for performing the genomics-based approaches in these *** this study,we proposed a method to estimate 14 haplotypes from 7 founders and automatically trace the haplotypes forward to apple parental(185 varieties)and breeding(659 F 1 individuals from 16 full-sib families)populations based on 11,786 single-nucleotide polymorphisms,by combining multiple ***,92%of the single-nucleotide polymorphisms information in the parental and breeding populations was characterized by the 14 founder *** use of founder haplotype information improved the accuracy of genomic prediction in 7 traits and the resolution of genome-wide association study in 13 out of 27 fruit quality traits analyzed in this *** also visualized the significant propagation of the founder haplotype with the largest genetic effect in genome-wide association study over the pedigree tree of the parental *** results suggest that the information of founder haplotypes can be useful for not only genetic improvement of fruit quality traits in apples but also for understanding the selection history of founder haplotypes in the breeding program of Japanese apple varieties.

关键词： breeding varieties prediction

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Tubulopapillary adenoma of the gallbladder accompanied by bile duct tumor thrombus

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World Journal of Gastroenterology 2014年第26期20卷 8736-8739页

作者： Kentaroh yamamoto Fumio yamamoto Atsuhiro Maeda Hirotsune Igimi Mami yamamoto Ryosuke Yamaguchi yuichi Yamashita Department of Surgery Yamamoto Memorial Hospital Department of Internal Medicine Maeda Hospital Department of Gastroenterological Surgery Fukuoka University School of Medicine

Intraductal papillary mucinous neoplasm of the bile duct(IPNB)is recognized as a precancerous lesion;however,both its pathogenesis and progression remain *** present here a case of IPNB arising from the gallbladder accompanied by bile duct tumor thrombus in a 79-year-old *** resected specimen revealed a tubulopapillary adenoma with no malignant *** case suggests that even in the absence of malignant cells,these tumors can behave as malignant tumors requiring aggressive *** if no malignant cells are present,intraepithelial neoplasms occurring in the ampullopancreatobiliary tract can behave as malignant tumors.

关键词： Intraductal papillary mucinous neoplasm of the bil

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A Possible Mechanism of Cisplatin-Induced Tumor Necrosis Factor (TNF)-α Production in Murine Macrophages

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Pharmacology & Pharmacy 2013年第2期4卷 146-151页

作者： Seikou Kim Kouichi yamamoto Yusuke Nakamura yuichi Otoyo Atsushi Yamatodani Laboratory of Pharmacology Department of Medical Science and Technology Division of Health Science Graduate School of Medicine Osaka University Osaka Japan

Cisplatin has been used for the treatment of various solid cancers or sarcomas;however, it can induce severe adverse effects. Among these adverse effects, nephrotoxicity, which has the potential to be a dose-limiting factor of this agent, develops due to the secretion of tumor necrosis factor-α (TNF-α) from macrophages;however, the precise mechanisms are still unclear. To elucidate possible mechanisms, we investigated the involvement of mitogen-activated protein kinases (MAPK) and reactive oxygen species (ROS) in cisplatin-induced TNF-α mRNA expression and protein production in the mouse macrophage-like cell line, RAW 264. Cisplatin (1 μM) significantly increased TNF-α mRNA expression and protein production. Extracellular-regulated kinase (ERK) and p38 MAPK, but not c-Jun N-terminal kinase (JNK), phosphorylation increased in response to cisplatin. Although an ERK inhibitor (PD98059) suppressed both cisplatin-induced TNF-α mRNA expression and its protein production, a p38 MAPK inhibitor (SB203580) decreased TNF-α protein production only. A JNK inhibitor (SP600125) had no effect on cisplatin-induced TNF-α mRNA expression. Furthermore, a scavenger of ROS, N,N’-dimethylthiourea, suppressed both ERK activation and TNF-α mRNA expression. These results suggest that the phosphorylation of ERK by ROS is involved in cisplatin-induced TNF-α mRNA expression and that the signaling pathway of p38 MAPK is related to TNF-α protein production.

关键词： Cisplatin Reactive Oxygen Species (ROS) Macrophage RAW264 MAPK TNF-α

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Acute pancreatitis successfully diagnosed by diffusion-weighted imaging: A case report

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World Journal of Gastroenterology 2008年第35期14卷 5478-5480页

作者： Satoshi Shinya Takamitsu Sasaki Yoshifumi Nakagawa Zhang Guiquing Fumio yamamoto yuichi Yamashita Department of Gastroenterological Surgery Yamamoto Memorial Hospital88-4 HachiyagaramiNirimachiImariSaga 848-0031Japan Department of Gastroenterological Surgery Fukuoka University School of MedicineNanakuma 7-45-1Jonan-kuFukuoka 814-0180Japan

Diffusion-weighted imaging (DWI) is an established diagnostic method of acute stroke. The latest advances in magnetic resonance imaging (MRI) technology have greatly expanded the utility of DWI in the examination of various organs. Recent studies have revealed the usefulness of DWI for imaging of the liver, kidney, ovary, and breast. We report a patient with acute pancreatitis detected by DWI and discussed the efficacy of DWI in diagnosing acute pancreatitis. A 50-year old man presented with a primary complaint of abdominal pain. We performed both DWI and computed tomography (CT) for this patient. The signal intensity in a series of DWI was measured and the apparent diffusion coefficient (ADC) values were calculated to differentiate inflammation from normal tissue. Two experienced radiologists evaluated the grade of acute pancreatitis by comparing the CT findings. Initially, the pancreas and multiple ascites around the pancreas produced a bright signal and ADC values were reduced on DWI. As the inflammation decreased, the bright signal faded to an iso-signal and the ADC values returned to their normal level. There was no difference in the abilities of DWI and CT images to detect acute pancreatitis. However, our case indicates that DWI can evaluate the manifestations of acute pancreatitis using no enhancement material andhas the potential to replace CT as a primary diagnostic strategy for acute pancreatitis.

关键词：急性胰腺炎加权扩散成像表观扩散常数磁共振成像诊断

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