检索结果-南通市图书馆

Inelastic Scattering of Dark Matter with Heavy Cosmic Rays

Research in Astronomy and Astrophysics 2024年第6期24卷 68-80页

作者： Keyu Lu yue-lin Sming tsai Qiang Yuan Le Zhang School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China CSST Science Center for the Guangdong-Hong Kong-Macao Greater Bay Area SYSUZhuhai 519082China Peng Cheng Laboratory Shenzhen 518000China

We investigate the impact of inelastic collisions between dark matter(DM)and heavy cosmic ray(CR)nuclei on CR *** approximate the fragmentation cross-sections for DM-CR collisions using collider-measured proton-nuclei scattering cross-sections,allowing us to assess how these collisions affect the spectra of CR boron and *** derive new CR spectra from DM-CR collisions by incorporating their cross-sections into the source terms and solving the diffusion equation for the complete network of reactions involved in generating secondary *** a specific example with a coupling strength of b_(χ)=0.1 and a DM mass of m_(χ)=0.1 GeV,considering a simplified scenario where DM interacts exclusively with oxygen,a notable modification in the boron-to-carbon spectrum due to the DM-CR interaction is ***,the peak within the spectrum,spanning from 0.1 to 10 GeV,experiences an enhancement of approximately 1.5 ***,in a more realistic scenario where DM particles interact with all CRs,this peak can be amplified to twice its original *** the latest data from AMS-02 and DAMPE on the boron-to-carbon ratio,we estimate a 95%upper limit for the effective inelastic cross-section of DM-proton as a function of DM *** findings reveal that at m_(χ)?2 MeV,the effective inelastic cross-section between DM and protons must be less than O(10^(-32))cm^(2).

关键词： elementary particles nuclear reactions nucleosynthesis abundances scattering astroparticle physics (cosmology:)dark matter

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

NMSSM neutralino dark matter for CDFⅡW-boson mass and muon g-2 and the promising prospect of direct detection

引用

Science China(Physics,Mechanics & Astronomy) 2023年第3期66卷 169-177页

作者： Tian-Peng Tang Murat Abdughani Lei Feng yue-lin Sming tsai Jian Wu Yi-Zhong Fan Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210033China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China School of Physical Science and Technology Xinjiang UniversityUrumqi 830046China Joint Center for Particle Nuclear Physics and CosmologyNanjing University-Purple Mountain ObservatoryNanjing 210093China

Two experiments from the Fermilab, E989 and CDF II, have reported two anomalies for muon g-2 and W-boson mass that may indicate the new physics at the low energy scale. Here we examine the possibility of a common origin of these two anomalies in the Next-to-Minimal Supersymmetric Standard Model. Considering various experimental and astrophysical constraints such as the Higgs mass, collider data, flavor physics, dark matter relic density, and direct detection experiments, we find that lighter electroweakinos and sleptons can generate sufficient contributions to muon g-2 and mW. Moreover, the corresponding bino-like neutralino dark matter mass is in the ~ 180-280 Ge V range. Interestingly, the favored dark matter(DM) mass region can soon be entirely probed by ongoing direct detection experiments like Panda X-4T, XENONn T, LUX-ZEPlin, and DARWIN.

关键词： supersymmetry dark matter W-boson muon g-2

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

HNF-4α determines hepatic differentiation of human mesenchymal stem cells from bone marrow

引用

World Journal of Gastroenterology 2010年第40期16卷 5092-5103页

作者： Mong-Liang Chen Kuan-Der Lee Huei-Chun Huang yue-lin tsai Yi-Chieh Wu Tzer-Min Kuo Cheng-Po Hu Chungming Chang Division of Molecular and Genomic Medicine National Health Research Institutes Department of Hematology and Oncology Chang Gung Memorial Hospital Institute of Microbiology and Immunology National Yang-Ming University Department of Life Science Tunghai University

AIM: To investigate the differentiation status and key factors to facilitate hepatic differentiation of human bone-marrow-derived mesenchymal stem cells (MSCs). METHODS: Human MSCs derived from bone marrow were induced into hepatocyte-like cells following a previously published protocol. The differentiation status of the hepatocyte-like cells was compared with various human hepatoma cell lines. Overexpression of hepatocyte nuclear factor (HNF)-4α was mediated by adenovirus infection of these hepatocyte-like cells. The expression of interesting genes was then examined by either re-verse transcription-polymerase chain reaction (RT-PCR) or real-time RT-PCR methods. RESULTS: Our results demonstrated that the differentiation status of hepatocyte-like cells induced from human MSCs was relatively similar to poorly differentiated human hepatoma cell lines. Interestingly, the HNF-4 isoform in induced MSCs and poorly differentiated human hepatoma cell lines was identified as HNF4γ instead of HNF-4α. Overexpression of HNF-4α in induced MSCs significantly enhanced the expression level of hepatic-specific genes, liver-enriched transcription factors, and cytochrome P450 (P450) genes. CONCLUSION: Overexpression of HNF-4α improves the hepatic differentiation of human MSCs from bone marrow and is a simple way of providing better cell sources for clinical applications.

关键词： Bone marrow Cytochrome P450 genes Differentiation of hepatocyte Hepatocyte nuclear factor 4 Human mesenchymal stem cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A common origin of muon g-2 anomaly,Galaxy Center GeV excess and AMS-02 anti-proton excess in the NMSSM

引用

Science Bulletin 2021年第21期66卷 2170-2174,M0003页

作者： Murat Abdughani Yi-Zhong Fan Lei Feng yue-lin Sming tsai Lei Wu Qiang Yuan Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Joint Center for Panicle.Nuclear Physics and Cosmology Nanjing University-Purple Mountain ObservatoryNanjing 210093China Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China

The supersymmetric model is one of the most attractive extensions of the Standard Model of particle *** light of the most recently reported anomaly of the muon g-2 measurement by the FermiLab E989 experiment,and the excesses of gamma rays at the Galactic center observed by Fermi-LAT space telescope,as well as the antiproton excess observed by the Alpha Magnetic Spectrometer,we propose to account for all these anomalies or excesses in the Next-to-Minimal Supersymmetric Standard Model(NMSSM).Considering various experimental constraints including the Higgs mass,B-physics,collider data,dark matter relic density and direct detections,we find that a~60 GeV bino-like neutralino is able to successfully explain all these *** scenario can be sensitively probed by future direct detection experiments.

关键词： Dark matter Supersymmetry Muon g-2 anomaly Galactic center GeV excess Anti-proton excess Global analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Regulation of integrated and covalently closed circular form of Hepatitis B virus (HBV) replication by cytokines

Regulation of integrated and covalently closed circular form...

引用

第五届海峡两岸细胞生物学学术研讨会

作者： Mong-Liang Chen Chin-Liew Chong yue-lin tsai Tzu-ling Liu King-Song Jeng National Health Research Institutes Zhunan MiaoliTaiwan

Chronic hepatitis B (CHB) is one of the most serious viral infections worldwide, which is also a high risk factor for cirrhosis and hepatocellular carcinoma (HCC). Several studies have reported that yirus persistence in CHB patients relies on maintaining a pool of viral covalently closed circular DNA (cccDNA) in the nuclei of infected hepatocytes, which presumably served as the template for HBV gene expression and viral replication. Apparently, cccDNA may play a pivotal role in the life cycle of HBV replication and may be responsible

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

镜像量子色动力学相变解释纳赫兹随机引力波背景

引用

Science Bulletin 2024年第6期69卷 741-746页

作者：祖磊张弛李垚钰顾玉超蔡岳霖范一中 Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China

Several Pulsar Timing Array(PTA)Collaborations have recently provided strong evidence for a n Hz Stochastic Gravitational-Wave Background(SGWB).Here we investigate the implications of a firstorder phase transition occurring within the early Universe's dark quantum chromodynamics epoch,specifically within the framework of the mirror twin Higgs dark sector *** analysis indicates a distinguishable SGWB signal originating from this phase transition,which can explain the measurements obtained by ***,a significant portion of the parameter space for the SGWB signal also effectively resolves the existing tensions in both the H_(0) and S_(8) measurements in *** intriguing correlation suggests a possible common origin of these three phenomena for 0.2<ΔN_(eff)<0.5,where the mirror dark matter component constitutes less than 30% of the total dark matter *** CMB experiments such as CMB-S4 can test this parameter region.

关键词： Mirror twin Higgs Dark matter Phase transition Gravitational wave Pulsar timing array

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Success of intravenous immunoglobulin and steroids in managing severe COVID-19 following lung transplantation:A case report

引用

World Journal of Transplantation 2025年第1期15卷 178-184页

作者： Yen-Shou Kuo Kuan-Hsun lin Ying-Yi Chen Yuan-Ming tsai Ti-Hui Wu Hsu-Kai Huang tsai-Wang Huang Division of Thoracic Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114202Taiwan

BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following *** immunoglobulin(IVIG)plays a role in both immune support and inflammation control,especially in immunocompromised *** case report describes the first successful experience using IVIG and pulse steroids to manage this critical condition following lung *** SUMMARY A 65-year-old male patient reported a history of chronic obstructive pulmonary disease and poor lung function and received bilateral sequential lung ***,he developed COVID-19 pneumonia,severe septic shock,and *** recovered from this critical condition after empirical antibiotics administration and veno-venous extracorporeal membrane oxygenation,in addition to IVIG and pulse *** IVIG is a valuable adjunct in managing severe sepsis in lung transplant recipients after COVID-19 *** aim,for the first time,to report the success of such a management approach for COVID-19 ARDS and sepsis in the post-lung transplant *** further investigations,this is a starting point for wider analysis of such an approach in this setting and consequently helps guide clinical practice for such a challenging patient population moving forward.

关键词： COVID-19 Septic shock Intravenous immunoglobulin Lung transplantation Post-transplant complications Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

引用

Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu Wei Wan Xiuqin Rao yue lin Gen Wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nanostructured ZnO/BiVO_(4)I-scheme heterojunctions for piezocatalytic degradation of organic dyes via harvesting ultrasonic vibration energy

引用

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 488-497页

作者： Yiling Li Xiaoyao Yu Yingjie Zhou Yao lin Ying Wu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step *** resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure *** 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and *** enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole ***,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active ***,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.

关键词： piezoelectric catalytic heterojunction dye degradation ultrasonic vibration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases

引用

Neural Regeneration Research 2025年第11期20卷 3076-3094页

作者： Xinyu Yang Xiangyu Gao Xiaofan Jiang Kangyi yue Peng Luo Department of Neurosurgery Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina

Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological *** to their therapeutic properties and ability to cross the blood–brain barrier,extracellular vesicles are recognized as promising drug delivery vehicles for various neurological conditions,including ischemic stroke,traumatic brain injury,neurodegenerative diseases,glioma,and ***,the clinical application of natural extracellular vesicles is hindered by their limited targeting ability and short clearance from the *** address these limitations,multiple engineering strategies have been developed to enhance the targeting capabilities of extracellular vesicles,thereby enabling the delivery of therapeutic contents to specific tissues or ***,this review aims to highlight the latest advancements in natural and targeting-engineered extracellular vesicles,exploring their applications in treating traumatic brain injury,ischemic stroke,Parkinson's disease,Alzheimer's disease,amyotrophic lateral sclerosis,glioma,and ***,we summarized recent clinical trials involving extracellular vesicles and discussed the challenges and future prospects of using targeting-engineered extracellular vesicles for drug delivery in treating neurological *** review offers new insights for developing highly targeted therapies in this field.

关键词： Alzheimer's disease amyotrophic lateral sclerosis engineered extracellular vesicles glioma ischemic stroke neurological diseases Parkinson's disease psychosis targeted drug delivery traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：