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Enhancement of Performance by Blade Optimization in Two-Stage Ring Blower

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Journal of Thermal Science 2010年第5期19卷 383-389页

作者： Choon-Man jang Gi-young Han Plant Research Division Korea Institute of Construction Technology dh-m co. ltd.626-5Bulmo-dongSeo-guIncheon404-270Korea

This paper describes the shape optimization of an impeller used for two-stage high pressure ring *** shape variables,which are used to define an impeller shape,are introduced to increase the blower *** pressure of a blower is selected as an object function,and the blade optimization is performed by a response surface ***-dimensional Navier-Stokes equations are introduced to analyze the internal flow of the blower and to find the value of object function for the training *** good agreement between experimental measurements and numerical simulation is obtained in the present *** the shape optimization,it is found that a hub height is effective to increase pressure in the ring *** pressure rise for the optimal two-stage ring blower is successfully increased up to 1.86% compared with that of reference at the design flow *** recirculation flow having low velocity is formed in both sides of the impeller outlet by different flow direction of the inlet and outlet of the *** flow field inside the ring blower is also analyzed and discussed.

关键词： Ring blower Blower performance Numerical simulation Blade optimization Response surface method

Neuroimaging characterization of recovery of impaired consciousness in patients with disorders of consciousness

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Neural Regeneration Research 2019年第7期14卷 1202-1207页

作者： Sung Ho jang young Hyeon Kwon Department of Physical Medicine and Rehabilitation College of MedicineYeungnam University

Elucidation of critical brain areas or structures that are responsible for recovery of impaired consciousness in patients with disorders of consciousness is important because it can provide information that is useful when developing therapeutic strategies for neurorehabilitation or neurointervention in patients with disorders of *** this review,studies that have demonstrated brain changes during recovery of impaired consciousness were *** studies used positron emission tomography,electroencephalography/transcranial magnetic stimulation,diffusion tensor tractography,and diffusion tensor tractography/*** majority of these studies reported on the importance of supratentorial areas or structures in the recovery of impaired *** important brain areas or structures that were identified were the prefrontal cortex,basal forebrain,anterior cingulate cortex,and parietal *** results have a clinically important implication that these brain areas or structures can be target areas for neurorehabilitation or neurointervention in patients with disorders of ***,most of studies were case reports;therefore,further original studies involving larger numbers of patients with disorders of consciousness are *** addition,more detailed information on the brain areas or structures that are relevant to the recovery of impaired consciousness is needed.

关键词： consciousness vegetative state minimally conscious state ascending reticular activating system diffusion tensor imaging neuroimaging neural regeneration review

Recent advances in electronic devices for monitoring and modulation of brain

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Nano Research 2021年第9期14卷 3070-3095页

作者： Yong Won Kwon Yoon Sun Jun young-Geun Park Jiuk jang jang-Ung Park Nano Science Technology Institute Department of Materials Science and EngineeringYonsei UniversitySeoul 03722Republic of Korea Center for Nanomedicine Institute for Basic Science(IBS)Seoul 03722Republic of Korea Graduate Program of Nano Biomedical Engineering(NanoBME) Advanced Science InstituteYonsei UniversitySeoul 03722Republic of Korea

The brain is actuated by billions of neurons with trillions of interconnections that regulate human *** the mechanisms of these systems that induce sensory reactions and respond to disease remains one of the greatest challenges in science,engineering,and *** advances in nanomaterials and nanotechnologies have led to the extensive research of electronic devices for brain interfaces to better understand the neural activities of the brains complex nervous *** development of sensor devices for monitoring the physiological signals of the brain related to traumatic injury status has accompanied by the progress of electronic neural probes in *** addition,these neurological and stereotactic surgical revolutions hold immense potential for clinical analysis of pharmacological systems within cerebral ***,we review the progress of electronic devices interfacing with brain in terms of the materials,fabrication technologies,and device *** activity can be measured and modulated by brain probes based on newly developed nanofabrication ***,in vivo pathological monitoring of the brain and pharmacological assessment has been developed in miniaturized and wireless *** also consider the key challenges and prospects for further development,and explore the future directions emerging in the latest research.

关键词： neural interfaces neural recording neuromodulation intracranial pressure monitoring microfluidic drug delivery

Torsional vibration analysis of lathe spindle system with unbalanced workpiece

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Journal of Central South University 2011年第1期18卷 171-176页

作者：郭瑞 jang Sung-Hyun CHOI young-Hyu School of Mechatronics Changwon National University

For the purpose of analyzing the torsional vibration caused by the gravitational unbalance torque arisen in a spindle system when it is machining heavy work piece,a 10-DOF lumped parameter model was made for the machine tool spindle system with geared *** using the elementary method and Runge-Kutta method in Matlab,the eigenvalue problem was solved and the pure torsional vibration responses were obtained and *** results show that the spindle system cannot operate in the desired constant rotating speed as far as the gravitational unbalance torque is engaged,so it may cause bad effect on machining *** the torsional vibration increases infinitely near the resonant frequencies,so the spindle system cannot operate normally during these spindle speed ranges.

关键词： unbalanced work piece gravitational unbalance torque torsional vibration spindle system geared transmission

Tribological properties of multilayer tetrahedral amorphous carbon coatings deposited by filtered cathodic vacuum arc deposition

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Friction 2021年第5期9卷 1292-1302页

作者： young-Jun jang Jae-Il KIM Wooyoung LEE Jongkuk KIM Department of Extreme Environmental Coatings Surface Technology DivisionKorea Institute of Materials Science(KIMS)Gyeongnam-do 51508Republic of Korea Department of Mechanical Science and Engineering Graduate School of EngineeringNagoya UniversityNagoya 464-8603Japan

Tetrahedral amorphous carbon(ta‐C)has emerged as an excellent coating material for improving the reliability of application components under high normal ***,we present the results of our investigations regarding the mechanical and tribological properties of a 2‐μm‐thick multilayer ta‐C coating on high‐speed steel *** composed of alternating soft and hard layers are fabricated using filtered a cathodic vacuum arc with alternating substrate bias voltages(0 and 100 V or 0 and 150 V).The thickness ratio is discovered to be 1:3 for the sp2‐rich and sp3‐rich *** results show that the hardness and elastic modulus of the multilayer ta‐C coatings increase with the sp3 content of the hard *** hardness reached approximately 37 GPa,whereas an improved toughness and a higher adhesion strength(>29 N)are *** friction performance(μ=0.07)of the multilayer coating is similar to that of the single layer ta‐C thick coating,but the wear rate(0.13×10^(–6) mm^(3)/(N∙m))improved under a high load of 30 *** further demonstrate the importance of the multilayer structure in suppressing crack propagation and increasing the resistance to plastic deformation(H3/E2)ratio.

关键词： tetrahedral amorphous carbon(ta‐C) filtered cathodic vacuum arc deposition multilayer coatings alternating substrate bias voltage wear resistance plastic deformation resistance

Development of genome engineering technologies in cattle: from random to specific

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Journal of Animal Science and Biotechnology 2018年第2期9卷 285-293页

作者： Soo-young Yum Ki-young Youn Woo-Jae Choi Goo jang Department of Veterinary Clinical Science College of Veterinary Medicine and the Research Institute of Veterinary Science Seoul National University Farm Animal Clinical Training and Research Center Institute of Green Bio Science Technology Seoul National University Emergence Center for Food-Medicine Personalized Therapy System Advanced Institutes of Convergence Technology Seoul National University College of Veterinary Medicine Seoul National University

The production of transgenic farm animals(e.g., cattle) via genome engineering for the gain or loss of gene functions is an important undertaking. In the initial stages of genome engineering, DNA micro-injection into one-cell stage embryos(zygotes) followed by embryo transfer into a recipient was performed because of the ease of the ***, as this approach resulted in severe mosaicism and has a low efficiency, it is not typically employed in the cattle as priority, unlike in mice. To overcome the above issue with micro-injection in cattle, somatic cell nuclear transfer(SCNT) was introduced and successfully used to produce cloned livestock. The application of SCNT for the production of transgenic livestock represents a significant advancement, but its development speed is relatively slow because of abnormal reprogramming and low gene targeting efficiency. Recent genome editing technologies(e.g.,ZFN, TALEN, and CRISPR-Cas9) have been rapidly adapted for applications in cattle and great results have been achieved in several fields such as disease models and bioreactors. In the future, genome engineering technologies wil accelerate our understanding of genetic traits in bovine and wil be readily adapted for bio-medical applications in cattle.

关键词： Cattle CRISPR-Cas9 Genome engineering technologies Transgenesis Transposon

Recent application of biochar on the catalytic biorefinery and environmental processes

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Chinese Chemical Letters 2019年第12期30卷 2147-2150页

作者： Hyung Won Lee Heejin Lee young-Min Kim rae-su Park young-Kwon Park School of Environmental Engineering University of SeoulSeoul 02504Republic of Korea Department of Environmental Engineering Daegu UniversityGyeongsan 38452Republic of Korea Department of Bioenvironmental&Chemical Engineering Chosun College of Science&TechnologyGwangju 61453Republic of Korea

Lignocellulosic biomass is an abundant and environment-friendly source for renewable energy *** value and application of biochar,which is obtained from the thermochemical conversion of biomass,is increasing rapidly because of its high carbon content and *** property of biochar,such as surface area,porosity,and number of functional groups,can be improved by controlling the conditions of biomass conversion,biochar activation,and functionalization *** production and activation of biochar as well as its potential use for soil remediation,pollutant adsorption,and biorefinery have been reviewed extensively over recent *** paper provides a conceptual approach for biochar production and activation together with its application as a catalyst for biorefineries and the removal of environmental contaminants.

关键词： Biomass Thermochemical conversion Biochar Activation Catalyst

Plasmid DNA-loaded asymmetrically porous membrane for guided bone regeneration

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Journal of Materials Science & Technology 2021年第4期63卷 161-171页

作者： Se Heang Oh June-Ho Byun So young Chun young-Joo jang Jin Ho Lee Department of Nanobiomedical Science Dankook UniversityCheonan 31116Republic of Korea Department of Oral and Maxillofacial Surgery Gyeongsang National University School of MedicineGyeongsang National University HospitalInstitute of Health SciencesGyeongsang National UniversityJinju 52727Republic of Korea BioMedical Research Institute Kyungpook National University HospitalDaegu 41404Republic of Korea Department of Advanced Materials Hannam UniversityDaejeon 34054Republic of Korea

Although bone defects can be restored spontaneously,bone reconstruction with sufficient strength and volume continues to be a challenge in clinical *** recent years,the use of a variety of biomaterials with bioactivity has been attempted to compensate for this ***,we fabricated a pDNA(encoding for BMP-2)-loaded asymmetrically porous polycaprolactone(PCL)/Pluronic F127 membrane as a bioactive guided bone regeneration(GBR)membrane,using a modified immersion-precipitation *** was observed that the GBR membrane allows continuous release of pDNA for more than20 *** pDNA was sufficiently transfected into human bone marrow stem cells(h BMSCs)without significant cytotoxicity and the gene-transfected cells showed prolonged synthesis of *** in vitro osteogenic differentiation and in vivo animal studies,the effective induction of osteogenic differentiation of h BMSCs and enhanced bone regeneration by the pDNA-loaded asymmetrically porous PCL/Pluronic F127 membrane was observed,suggesting that the pDNA-loaded membrane as a bioactive GBR membrane can be an alternative therapeutic technique for effective bone regeneration.

关键词： loaded porous attempted

Expression of a High Mobility Group Protein Isolated from Cucumis sativus Affects the Germination of Arabidopsis thaliana under Abiotic Stress Conditions

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Journal of Integrative Plant Biology 2008年第5期50卷 593-600页

作者： Ji young jang Kyung Jin Kwak Hunseung Kang Department of Plant Biotechnology Agricultural Plant Stress Research Center and Biotechnology Research InstituteCollege of Agriculture and Life SciencesChonnam National UniversityGwangju 500-757Korea

Although high mobility group B （HMGB） proteins have been identified from a variety of plant species, their importance and functional roles in plant responses to changing environmental conditions are largely unknown. Here, we investigated the functional roles of a CsHMGB isolated from cucumber （Cucumis sativus L.） in plant responses to environmental stimuli. Under normal growth conditions or when subjected to cold stress, no differences in plant growth were found between the wild-type and transgenic Arabidopsis thaliana overexpressing CsHMGB. By contrast, the transgenic Arabidopsis plants displayed retarded germination compared with the wild-type plants when grown under high salt or dehydration stress conditions. Germination of the transgenic plants was delayed by the addition of abscisic acid （ABA）, implying that CsHMGB affects germination through an ABA-dependent way. The expression of CsHMGB had affected only the germination stage, and CsHMGB did not affect the seedling growth of the transgenic plants under the stress conditions. The transcript levels of several germination-responsive genes were modulated by the expression of CsHMGB in Arabidopsis. Taken together, these results suggest that ectopic expression of a CsHMGB in Arabidopsis modulates the expression of several germinationresponsive genes, and thereby affects the germination of Arabidopsis plants under different stress conditions.

关键词： abiotic stress cucumber Cucumis sativus high mobility group protein transgenic Arabidopsis plant.