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X-reality for phantom limb management for amputees:A systematic review and meta-analysis

Engineered Regeneration 2023年第2期4卷 134-151页

作者： James chung-Wai Cheung Daphne Sze Ki Cheung Ming Ni Kam-Wai Chen Ye-Jiao Mao Lin Feng Wing-Kai lam Duo Wai-Chi Wong Aaron Kam-Lun Leung Department of Biomedical Engineering Faculty of EngineeringThe Hong Kong Polytechnic UniversityHong KongChina School of Nursing The Hong Kong Polytechnic UniversityHong KongChina Department of Orthopaedics Ruijin HospitalShanghai Jiao Tong UniversityShanghaiChina Department of Prosthetics and Orthotics Queen Mary HospitalHong KongChina Sports Information and External Affairs Centre Hong Kong Sports InstituteHong KongChina Research Institute for Sports Science and Technology The Hong Kong Polytechnic UniversityHong KongChina Department of Rehabilitation Science The Hong Kong Polytechnic UniversityHong KongChina

Phantom limb is a disabling neuropsychiatric condition among amputees resulting in pain and disturbance that impact their functions,quality of life,and *** pharmacological approaches appeared to be ineffec-tive,the emergence and integration of X-reality,including virtual reality,augmented reality,and mixed reality,might elevate the effectiveness of mirror therapy in managing phantom *** objective of this study is to review X-reality for managing phantom pain.A systematic search was conducted on PubMed,Scopus,Web of Science,PsycINFO,Embase,and ***(n=16)studies containing 66 lower-limb and 53 upper-limb amputees were included for the review over the thematic framework of amputee characteristics and intervention designs,while thirteen(n=13)studies were further proceeded for the *** found eleven studies on virtual reality(n=11),four studies on marker-based augmented reality(n=4)and one study on mixed reality(n=1)with a total of 40 game/task themes involving,motor skills,motor control,and ***,all these interventions adopted the movement representation strategies with different ***,the X-reality interventions reduced the pain level of the amputees(mean difference:-2.30,95%CI,-3.38 to-1.22),especially the virtual reality subgroup(mean difference:-2.83,95%CI,-4.43 to-1.22).However,there were substantial heterogeneity and partially explained by the subgroup analysis on publication *** strength of evidence was limited by case reports and case series in this review.

关键词： Extended reality Limb telescoping Phantom pain Phantom sensation

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Analysis of inborn errors of metabolism： disease spectrum for expanded newborn screening in Hong Kong

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Chinese Medical Journal 2011年第7期124卷 983-989页

作者： Han-Chih Hencher Lee Chloe Miu Mak Ching-Wan lam Yuet-Ping Yuen, Angel On-Kei Chan Chi-chung Shek Tak-Shing Siu Chi-Kong Lai Chor-Kwan Ching Wai-Kwan Siu Sammy Pak-lam Chen Chun-yiu Law Morris Hok-Leung Tai Sidney Tam Albert Yan-Wo Chan Chemical Pathology Laboratory Department of Pathology Princess Margaret Hospital Hong Kong SAR China Division of Clinical Biochemistry Queen Mary Hospital Hong Kong SAR China Department of Pathology Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China Chemical Pathology Laboratory Department of Pathology Queen Elizabeth Hospital Hong Kong SAR China

Background Data of classical inborn errors of metabolism （IEM） of amino acids, organic acids and fatty acid oxidation are largely lacking in Hong Kong, where mass spectrometry-based expanded newborn screening for IEM has not been initiated. The current study aimed to evaluate the approximate incidence, spectrum and other characteristics of classical IEM in Hong Kong, which would be important in developing an expanded newborn screening program for the local area.

关键词： biochemical genetics chemical pathology expanded newborn screening Hong Kong," inborn errorsof metabolism tandem mass spectrometry

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Telling Duckweed Apart:Genotyping Technologies for the Lemnaceae

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应用与环境生物学报 2013年第1期19卷 1-10页

作者： Klaus J.Appenroth Nikolai Borisjuk Eric lam University of Jena Institute of General Botany and Plant Physiology Plant Biology and Pathology Rutgers State University of New Brunswick

The family of Lemnaceae,commonly called duckweed,comprise five genera and 37 species of aquaticmonocotyledonous plants that are endemic to lakes,ponds and brackish water bodies on most continents. They are angiospermsthat have the highest biomass production rate and have been used to remediate wastewater from both municipal andindustrial sources. With these attractive features,duckweed is poised to be a novel agricultural platform that can complementcurrent terrestrial crops. In addition,their remarkable ability to adapt to diverse climates and conditions may provide newunderstanding of stress tolerance and genome adaptability mechanisms. However,one of the first challenges facing theseapplications is to establish reliable and rapid methods for identification of closely related strains that may have very differentbehaviour or properties. This review article summarizes the state of the arts for this endeavour and provides the outlook for thisquest in the near future.

关键词： RAPD ISSR AFLP 环境生物学

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Atomistic simulation of free transverse vibration of graphene,hexagonal SiC, and BN nanosheets

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Acta Mechanica Sinica 2017年第1期33卷 132-147页

作者： Danh-Truong Nguyen Minh-Quy Le Thanh-lam Bui Hai-Le Bui School of Mechanical Engineering Hanoi University of Science and Technology Hanoi 10000 Vietnam International Institute for Computational Science and Engineering Hanoi University of Science and TechnologyHanoi 10000 Vietnam Faculty of Mechanical Engineering Hanoi University of Industry Hanoi 10000 Vietnam

Free transverse vibration of monolayer graphene, boron nitride (BN), and silicon carbide (SiC) sheets is investigated by using molecular dynamics finite element method. Eigenfrequencies and eigenmodes of these three sheets in rectangular shape are studied with different aspect ratios with respect to various boundary conditions. It is found that aspect ratios and boundary conditions affect in a similar way on natural frequencies of graphene, BN, and SiC sheets. Natural frequencies in all modes decrease with an increase of the sheet’s size. Graphene exhibits the highest natural frequencies, and SiC sheet possesses the lowest ones. Missing atoms have minor effects on natural frequencies in this study.

关键词： Atomistic simulation Hexagonal sheet Transverse vibration Molecular dynamics finite element method

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Endohepatology:Arrival at the frontier of interventional endosonography

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World Journal of Gastroenterology 2024年第18期30卷 2397-2401页

作者： Shane P Selvanderan Eric lam Neal Shahidi Department of Medicine University of British ColumbiaVancouver V6Z 1Y6BCCanada

Endohepatology describes the emerging field where diagnostic and therapeutic endoscopic ultrasound(EUS)are used for the diagnosis and management of liver disease and its *** this editorial we comment on the article by Gadour et *** spectrum of EUS-guided procedures includes liver parenchymal and lesional biopsy,abscess drainage,treatment of focal liver lesions,diagnosis of portal hypertension and management of gastric *** data suggest that the application of EUS to hepatology is technically feasible and safe,heralding the arrival at a new frontier for *** data,specifically randomised trials comparing EUS to interventional radiology techniques,and continued partnership between endoscopy and hepatology are required to see this field establish itself outside expert tertiary centres.

关键词： Cancer Cirrhosis Endoscopy Endoscopic ultrasound Liver disease

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Traditional Chinese medicine poisoning in the emergency departments in Hong Kong: Trend, clinical presentation and predictors for poor outcome

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World Journal of Emergency Medicine 2021年第2期12卷 143-150页

作者： Rex Pui Kin lam Eric Ho Yin Lau Wai lam Yip Joe Kai Shing Leung Matthew Sik Hon Tsui Emergency Medicine Unit Li Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina Accident and Emergency Department Queen Mary HospitalHong KongChina Accident and Emergency Department Pamela Youde Nethersole Eastern HospitalHong KongChina School of Public Health Li Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina

Dear editor,Traditional Chinese medicine (TCM) is popular in many countries,especially in the Chinese population.^([1,2]) In Hong Kong,it has been estimated that around 15%of the population consumed Chinese medicine products/herbs in the preceding *** reasons for consumption include regulating bodily functions,curing disease,and building up health.

关键词： has editor curing

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Plasmonic metasurfaces with 42.3% transmission efficiency in the visible

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Light(Science & Applications) 2019年第1期8卷 711-723页

作者： Jihua Zhang Mohamed ElKabbash Ran Wei Subhash CSingh Billy lam Chunlei Guo The Institute of Optics University of RochesterRochesterNY 14627USA Changchun Institute of Optics Fine Mechanicsand PhysicsChinese Academy of Sciences130033 ChangchunChina

Metasurfaces are two-dimensional nanoantenna arrays that can control the propagation of light at *** particular,plasmonic metasurfaces feature ultrathin thicknesses,ease of fabrication,field confinement beyond the diffraction limit,superior nonlinear properties,and ultrafast ***,the technological relevance of plasmonic metasurfaces operating in the transmission mode at optical frequencies is questionable due to their limited *** state-of-the-art efficiency of geometric plasmonic metasurfaces at visible and near-infrared frequencies,for example,is ≤10%.Here,we report a multipole-interference-based transmission-type geometric plasmonic metasurface with a polarization conversion efficiency that reaches 42.3% at 744 nm,over 400% increase over the state of the *** efficiency is augmented by breaking the scattering symmetry due to simultaneously approaching the generalized Kerker condition for two orthogonal *** addition,the design of the metasurface proposed in this study introduces an air gap between the antennas and the surrounding media that confines the field within the gap,which mitigates the crosstalk between meta-atoms and minimizes metallic *** proposed metasurface is broadband,versatile,easy to fabricate,and highly tolerant to fabrication *** highlight the technological relevance of our plasmonic metasurface by demonstrating a transmission-type beam deflector and hologram with record efficiencies.

关键词： visible surfaces approaching

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Conjugated polymers developed from alkynes

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National Science Review 2015年第4期2卷 493-509页

作者： Yajing Liu Jacky W.Y.lam Ben Zhong Tang HKUST-Shenzhen Research Institute Department of Chemistry Division of Life Science State Key Laboratory of Molecular NeuroscienceInstitute for Advanced Study Institute of Molecular Functional Materials and Division of Biomedical Engineering The Hong Kong University of Science and Technology Guangdong Innovative Research Team SCUT-HKUST Joint Research Laboratory State Key Laboratory of Luminescent Materials and Devices South China University of Technology

The numerous merits of conjugated polymers(CPs) have encouraged scientists to develop a variety of synthetic routes to CPs with diverse structures and functionalities. Among the large scope of substrates,alkyne plays an important role in constructing polymers with conjugated backbones. In addition to some well-developed reactions including Glaser–Hay and Sonogashira coupling, azide/thiol-yne click reaction and cyclotrimerization, some novel alkyne-based reactions have also been explored such as oxidative polycoupling, decarbonylative polycoupling and multicomponent tandem polymerizations. his review focuses on the recent progress on the synthetic methodology of CPs in the last ive years using monomers with two or more triple bonds and some of their high-technological applications. Selected examples of materials properties of these CPs are given in this review, such as luorescence response to chemical or physical stimuli, magnetism, white light emission, cell imaging and bioprobing. Finally, a short perspective is raised in regard to the outlook of the preparation methodologies, functionalities as well as potential applications of CPs in the future.

关键词： conjugated polymer alkyne synthetic methodology functional polymer

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Simultaneous harvesting and cell disruption of microalgae using ozone bubbles:optimization and characterization study for biodiesel production

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Frontiers of Chemical Science and Engineering 2021年第5期15卷 1257-1268页

作者： Wan N.A.Kadir Man K.lam Yoshimitsu Uemura Jun W.Lim Peck L.Kiew Steven Lim Siti S.Rosli chung Y.Wong Pau L.Show Keat T.Lee Chemical Engineering Department Universiti Teknologi PETRONASSeri Iskandar32610Malaysia HICoE-Centre for Biofuel and Biochemical Research Institute of Self-Sustainable BuildingUniversiti Teknologi PETRONASSeri Iskandar32610Malaysia NPO Kuramae Bioenergy Tokyo108-0023Japan Fundamental and Applied Sciences Department Universiti Teknologi PETRONASSeri Iskandar32610Malaysia Faculty of Engineering Technology&Built EnvironmentUniversity College Sedaya InternationalCheras Kuala Lumpur56000Malaysia Department of Chemical Engineering Lee Kong Chian Faculty of Engineering and ScienceUniversiti Tunku Abdul RahmanSungai LongSelangor43000Malaysia Department of Chemical and Environmental Engineering Faculty of Science and EngineeringUniversity of Nottingham MalaysiaSemenyih43500Malaysia School of Chemical Engineering Universiti Sains MalaysiaEngineering CampusNibong Tebal14300Malaysia

In the present study, ozone was introduced as an alternative approach to harvest and disrupt microalgae cells (Chlorella vulgaris) simultaneously for biodiesel production. At the optimum ozonation conditions (6.14 g·h^(−1) ozone concentration, 30 min ozonation time, 1 L·min^(−1) of ozone flowrate at medium pH of 10 and temperature of 30℃), the sedimentation efficiency of microalgae cells increased significantly from 12.56% to 68.62%. It was observed that the microalgae cells aggregated to form flocs after pretreated with ozone due to the increment of surface charge from −20 to −6.59 mV. Besides, ozone had successfully disrupted the microalgae cells and resulted in efficient lipid extraction, which was 1.9 times higher than the control sample. The extracted microalgae lipid was mainly consisted of methyl palmitate (C16:0), methyl oleate (C18:1) and methyl linolenate (C18:3), making it suitable for biodiesel production. Finally, utilization of recycled culture media after ozonation pre-treatment showed robust growth of microalgae, in which the biomass yield was maintained in the range of 0.796 to 0.879 g ·h^(−1) for 5 cycles of cultivation.

关键词： microalgae biodiesel ozonation pre-treatment lipid

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Technical note on ALPPS for a patient with advanced hepatocellular carcinoma associated with invasion of the inferior vena cava

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Hepatobiliary & Pancreatic Diseases International 2016年第3期15卷 319-323页

作者： Tan To Cheung Tiffany Cho lam Wong See Ching Chan Department of Surgery The University of Hong Kong

Patients with hepatocellular carcinoma have a very short life expectancy if they receive no surgical interven- tion. A relatively new surgical technique termed ＂Associating Liver Partition and Portal Vein Ligation for Staged Hepa- tectomy＂（ALPPS） has been employed for inducing rapid hypertrophy of the future liver remnant for patients waiting for hepatectomy. As portal vein embolization may not result in satisfactory hypertrophy before tumor progression occurs, ALPPS can be an alternative for patients with advanced hepa- tocellular carcinoma. Herein we describe an ALPPS procedure with tumor thrombectomy for a patient who had a small left liver lobe and a large hepatocellular carcinoma involving the whole right liver lobe and the middle hepatic vein and extend- ing into the inferior vena cava. In the first-stage operation, the right portal vein was controlled and divided with a Hemolock. The right hepatic artery was well protected. Hepatic transec- tion was performed with a 1-cm margin from the tumor. The middle hepatic vein trunk was preserved. Ten days afterwards, there was significant hypertrophy of the left lateral section of the liver, and the second-stage operation was conducted. Ex- tended right hepatectomy and tumor thrombectomy were per- formed under sternotomy and total vascular exclusion. The patient had good recovery and was free of disease 10 months after the operation. ALPPS may be a good treatment option even for patients with advanced disease if carried out at high- volume centers.

关键词： anatomy hepatocellular carcinoma therapeutics survival surgical procedure

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