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Dynamic lithium-compensation mechanism for densification of garnet-type Li_(7)La_(3)Zr_(2)O_(12)electrolyte by Li_(2)O atmosphere buffer pair

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Nano Research 2024年第7期17卷 6184-6191页

作者： Chujun Zheng ya Chen Haoxin Dong yan lu Jun Jin Zhaoyin Wen CAS Key Laboratory of Materials for Energy Conversion Shanghai Institute of CeramicsChinese Academy of ScienceShanghai 200050China State Key Lab High Performance Ceram and Superfine Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Solid-state lithium metal batteries are one of the most promising options for next-generation batteries pursuing high-energy density and ***,the inevitable volatilization of lithium compounds during sintering leads to low relative density and low ionic conductivity of solid-state ***,the dynamic lithium-compensation mechanism is proposed to facilitate the densification of Ta-substituted garnet-type electrolyte(Li_(6.5)La_(3)Zr_(1.5)Ta_(0.5)O_(12)(LLZT))through the reversible manipulating of Li_(2)O ***_(2)ZrO_(3)is used as mother powder additive,which reacts with Li_(2)O in sintering atmosphere and forms Li_(6)Zr_(2)O_(7).Li_(2)ZrO_(3)/Li_(6)Zr_(2)O_(7)buffer pair manipulates the sintering Li_(2)O atmosphere,which is vital for LLZT,within the Li_(2)O partial pressure range corresponding to Li_(2)ZrO_(3)and Li_(6)Zr_(2)O_(7).Furthermore,the reversibility mechanism of buffer pair for Li_(2)O absorption and release is *** obtained LLZT exhibits a relative density of over 96%and an ionic conductivity exceeding 7×10^(−4)S·cm^(−1)with no abnormal grain *** symmetric cell demonstrates an excellent lithium dendrite suppressing ability(stable cycling at a current density of 0.3 mA·cm^(−2)for over 1000 h).Such dynamic lithium-compensation strategy has been successfully applied in atmosphere manipulation of LLZT sintering process,which reduces the dependence of LLZT on the Li_(2)O atmosphere,making it conducive to large-scale preparation of electrolyte ceramics.

关键词： solid-state batteries garnet-type electrolyte high-density electrolyte dynamic lithium-compensation buffer pair

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Analysis of the one-decoy-state SARG04 quantum cryptography protocol in the presence of afterpulse effects

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Communications in Theoretical Physics 2024年第6期76卷 66-71页

作者： Hu Nian ya-Feng Nie Chun-Mei Zhang Liang-Liang lu Key Laboratory of Optoelectronic Technology of Jiangsu Province School of Physical Science and TechnologyNanjing Normal UniversityNanjing 210023China Institute of Quantum Information and Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China Hefei National Laboratory Hefei 230088China

The SARG04 quantum key distribution protocol can offer greater robustness against photon number splitting attacks than the BB84 protocol that is implemented with weak *** this paper,we propose a tight key analysis for the SARG04 protocol,by considering the one-decoy method and investigating its performance under the influence of a detector *** results demonstrate that an increase in block size leads to a slight increase in both the secure key rate and the maximum transmission ***,the detector afterpulse plays a crucial role in practical applications and has a more pronounced effect on the SARG04 protocol compared to the BB84 protocol.

关键词： Quantum key distribution SARG04 protocol one decoy afterpulse

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Ubiquitin-specific protease 21 promotes tumorigenicity and stemness of colorectal cancer by deubiquitinating and stabilizing ZEB1

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1006-1018页

作者： Jun-Jun lin Ye-Cai lu Department of Gastrointestinal Surgery Chaohu Hospital of Anhui Medical UniversityChaohu 238000Anhui ProvinceChina

BACKGROUND Colorectal cancer(CRC)is one very usual tumor together with higher death ***-specific protease 21(USP21)has been confirmed to take part into the regulation of CRC progression through serving as a ***,the promotive function of USP21 has also discovered in the progression of ***1 has illustrated to be modulated by USP7,USP22 and USP51 in ***,the regulatory functions of USP21 on ZEB1 in CRC progression need more *** To investigate the relationship between USP21 and ZEB1 in CRC *** The mRNA and protein expressions were assessed through RT-qPCR,western blot and IHC *** interaction between USP21 and ZEB1 was evaluated through Co-IP and GST pull down *** cell proliferation was detected through colony formation *** cell migration and invasion abilities were determined through Transwell *** stemness was tested through sphere formation *** tumor growth was evaluated through in vivo mice *** In this work,USP21 and ZEB1 exhibited higher expression in CRC,and resulted into poor ***,the interaction between USP21 and ZEB1 was further *** was demonstrated that USP21 contributed to the stability of ZEB1 through modulating ubiquitination *** addition,USP21 streng-thened cell proliferation,migration and stemness through regulating *** last,through in vivo assays,it was illustrated that USP21/ZEB1 axis aggravated tumor *** For the first time,these above findings manifested that USP21 promoted tumorigenicity and stemness of CRC by deubiquitinating and stabilizing *** discovery suggested that USP21/ZEB1 axis may provide novel sights for the treatment of CRC.

关键词： Ubiquitin-specific protease 21 ZEB1 Stemness Colorectal cancer

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Solar-and/or Radiative Cooling-Driven Thermoelectric Generators:A Critical Review

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Energy Engineering 2024年第10期121卷 2681-2718页

作者： Jinglong Wang lin lu Kai Jiao Department of Building Environment and Energy Engineering The Hong Kong Polytechnic UniversityHong Kong999077China

Thermoelectric generators(TEGs)play a critical role in collecting renewable energy fromthe sun and deep space to generate clean *** their environmentally friendly,reliable,and noise-free operation,TEGs offer diverse applications,including areas with limited power infrastructure,microelectronic devices,and wearable *** review thoroughly analyses TEG system configurations,performance,and applications driven by solar and/or radiative cooling,covering non-concentrating,concentrating,radiative cooling-driven,and dual-mode *** for solar absorbers and radiative coolers,simulation techniques,energy storage management,and thermal management strategies are *** integration of TEGs with combined heat and power systems is identified as a promising ***,TEGs hold potential as charging sources for electronic *** comprehensive review provides valuable insights into this energy collection approach,facilitating improved efficiency,reduced costs,and expanded *** also highlights current limitations and knowledge gaps,emphasizing the importance of further research and development in unlocking the full potential of TEGs for a sustainable and efficient energy future.

关键词： Thermoelectric generators solar energy radiative sky cooling applications

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Jianpi Qinghua Formula Alleviates Diabetic Myocardial Injury Through Inhibiting JunB/c-Fos Expression

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Current Medical Science 2024年第1期44卷 144-155页

作者： lin WANG Qing-guang CHEN Hao lu Department of Endocrinology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Traditional Chinese Medicine Naval Medical UniversityShanghai 200433China

Objective Diabetic cardiomyopathy(DCM)represents a substantial risk factor for heart failure and increased mortality in individuals afflicted with diabetes mellitus(DM).DCM typically manifests as myocardial fibrosis,myocardial hypertrophy,and impaired left ventricular diastolic *** the clinical utility of the Jianpi Qinghua(JPQH)formula has been established in treating diabetes and insulin resistance,its potential efficacy in alleviating diabetic cardiomyopathy remains *** study aims to investigate the impact and underlying molecular mechanisms of the JPQH formula(JPQHF)in ameliorating myocardial injury in nonobese diabetic rats,specifically focusing on apoptosis and *** Wistar rats were assigned as the normal control group(CON),while Goto-Kakizaki(GK)rats were randomly divided into three groups:DM,DM treated with the JPQHF,and DM treated with metformin(MET).Following a 4-week treatment regimen,various biochemical markers related to glucose metabolism,cardiac function,cardiac morphology,and myocardial ultrastructure in GK rats were *** sequencing was utilized to analyze differential gene expression and identify potential therapeutic *** vitro experiments involved high glucose to induce apoptosis and inflammation in H9c2 *** viability was evaluated using CCK-8 assay,apoptosis was monitored via flow cytometry,and the production of inflammatory cytokines was measured using quantitative real-time PCR(qPCR)and *** expression levels were determined by Western blotting *** investigation also incorporated the use of MAPK inhibitors to further elucidate the mechanism at both the transcriptional and protein *** The JPQHF group exhibited significant reductions in interventricular septal thickness at end-systole(IVSs)and left ventricular internal diameter at end-systole and end-diastole(LVIDs and LVIDd).JPQHF effectively suppressed high glucose-induced activation of IL-1βand caspase 3 in

关键词： Jianpi Qinghua formula diabetic cardiomyopathy AP-1 transcription factor apoptosis inflammation

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Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release

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Virologica Sinica 2024年第1期39卷 24-30页

作者： Jia Li Yong lin Xueyu Wang Mengji lu Institute for Virology University Hospital EssenUniversity of Duisburg-EssenEssen45122Germany Key Laboratory of Molecular Biology of Infectious Diseases(Chinese Ministry of Education) Chongqing Medical UniversityChongqing400016China The Key Laboratory for Diagnosis and Treatment of Infectious Diseases The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou310000China

Hepatitis B virus(HBV)produces and releases various particle types,including complete virions,subviral particles with envelope proteins,and naked *** studies demonstrate that HBV exploits distinct intracellular membrane trafficking pathways,including the endosomal vesicle trafficking and autophagy pathway,to assemble and release viral and subviral ***,we summarize the findings about the distinct roles of autophagy and endosomal membrane trafficking and the interaction of both pathways in HBV replication,assembly,and release.

关键词： Amphisome Autophagy Endosomal vesicle Hepatitis B virus(HBV)

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Self-Driven Photo-Polarized Water Molecule-Triggered Graphene-Based Photodetector

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Research 2024年第2期2023卷 273-283页

作者： Shisheng lin Chang Liu Xin Chen Yi Zhang Hongtao lin Xutao Yu Yujiao Bo yanghua lu College of Information Science and Electronic Engineering Zhejiang UniversityHangzhou 310027P.R.China Hangzhou Gelanfeng Technology Co.Ltd Hangzhou 310051P.R.China State Key Laboratory of Modern Optical Instrumentation Zhejang UniversityHangzhou 310027P.R.China Key Laboratory of Wide Bandgap Semiconductor Materials and Devices HCSemitek CorporationYiwu 322009P.R.China Smart Materials for Architecture Research Lab Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100P.R.China

Flowing water can be used as an energy source for generators,providing a major part of the energy for daily ***,water is rarely used for information or electronic ***,we present the feasibility of a polarized liquid-triggered photodetector in which polarized water is sandwiched between graphene and a *** to the polarization and depolarization processes of water molecules driven by photogenerated carriers,a photo-sensitive current can be repeatedly produced,resulting in a high-performance *** response wavelength of the photodetector can be fine-tuned as a result of the free choice of semiconductors as there is no requirement of lattice match between graphene and the *** zero voltage bias,the responsivity and specific detectivity of Gr/NaCl(0.5 M)W/N-GaN reach values of 130.7 mA/W and 2.3×10^(9)Jones under 350 nm illumination,***,using a polar liquid photodetector can successfully read the photoplethysmography signals to produce accurate oxygen blood saturation and heart *** with the commercial pulse oximetry sensor,the average errors of oxygen saturation and heart rate in the designed photoplethysmography sensor are~1.9%and~2.1%,*** study reveals that water can be used as a high-performance photodetector in informative industries.

关键词： polarization polarized saturation

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Efficient Spin-Flip between Charge-Transfer States for High-Performance Electroluminescence, without an Intermediate Locally Excited State

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Research 2024年第1期2023卷 339-349页

作者： Donghai Zhang Shanshan Jiang Xiaodong Tao Fulin lin lingyi Meng Xu-lin Chen Can-Zhong lu State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002China Fujian Science and Technology Innovation Laboratory for Optoelectronic Information of China FuzhouFujian 350108China Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstitutesChinese Academy of SciencesXiamenFujian 361021China University of Chinese Academy of Sciences Beijing 100049China

Thermally activated delayed fluorescence(TADF)materials with both high photoluminescence quantum yield(PLQY)and fast reverse intersystem crossing(RISC)are strongly desired to realize efficient and stable organic light-emitting diodes(OLEDs).Control of excited-state dynamics via molecular design plays a central role in optimizing the PLQY and RISC rate of TADF materials but remains ***,3 TADF emitters possessing similar molecular structures,similar high PLQYs(89.5%to 96.3%),and approximate energy levels of the lowest excited singlet states(S_(1)),but significantly different spin-flipping RISC rates(0.03×10^(6) s^(−1) vs.2.26×10^(6) s^(−1))and exciton lifetime(297.1 to 332.8μs vs.6.0μs)were systematically synthesized to deeply investigate the feasibility of spin-flip between charge-transfer excited states(^(3)CT–^(1)CT)transition.

关键词： transition lifetime desired

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The Implications of Artificial Intelligence on Infection Prevention and Control: Current Progress and Future Perspectives

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China CDC weekly 2024年第35期6卷 901-904页

作者： lin yang Shuya lu Lei Zhou School of Nursing The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina Chinese Center for Disease Control and Prevention BeijingChina

The rapid advancement of artificial intelligence(AI)has significantly impacted infection prevention and control,particularly amid the coronavirus disease 2019(COVID-19)pandemic(1).AI techniques such as machine learning(ML),deep learning,and natural language processing(NLP)have successfully transformed infection prevention and control strategies(1).These technologies have enhanced our understanding of infectious diseases,facilitated disease transmission prediction,and improved public health emergency responses(2).

关键词： has such prevention

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A NONLOCAL KRONECKER-BASIS-REPRESENTATION METHOD FOR LOW-DOSE CT SINOGRAM RECOVERY

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Journal of Computational Mathematics 2024年第4期42卷 1080-1108页

作者： Jian lu Huaxuan Hu Yuru Zou Zhaosong lu Xiaoxia Liu Keke Zu lin Li Shenzhen Key Laboratory of Advanced Machine Learning and Applications College of Mathematics and StatisticsShenzhen UniversityShenzhen 518060China National Center for Applied Mathematics Shenzhen(NCAMS) Shenzhen 518055China Department of Industrial and Systems Engineering University of Minnesota Twin CitiesMinneapolisMN55455USA Department of Applied Mathematics The Hong Kong Polytechnic UniversityHong Kong SARChina School of Electronic Engineering Xidian UniversityXi'an 710071China

Low-dose computed tomography(LDCT)contains the mixed noise of Poisson and Gaus-sian,which makes the image reconstruction a challenging *** order to describe the statistical characteristics of the mixed noise,we adopt the sinogram preprocessing as a stan-dard maximum a posteriori(MAP).Based on the fact that the sinogram of LDCT has non-local self-similarity property,it exhibits low-rank *** conventional way of solving the low-rank problem is implemented in matrix forms,and ignores the correlations among similar patch *** avoid this issue,we make use of a nonlocal Kronecker-Basis-Representation(KBR)method to depict the low-rank problem.A new denoising model,which consists of the sinogram preprocessing for data fidelity and the nonlocal KBR term,is developed in this *** proposed denoising model can better illustrate the generative mechanism of the mixed noise and the prior knowledge of the ***-merical results show that the proposed denoising model outperforms the state-of-the-art algorithms in terms of peak-signal-to-noise ratio(PSNR),feature similarity(FSIM),and normalized mean square error(NMSE).

关键词： Low-dose computed tomography Kronecker-basis-representation Low-rank imation.Noise-generating-mechanism

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