Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release
作者机构:Institute for VirologyUniversity Hospital EssenUniversity of Duisburg-EssenEssen45122Germany Key Laboratory of Molecular Biology of Infectious Diseases(Chinese Ministry of Education)Chongqing Medical UniversityChongqing400016China The Key Laboratory for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou310000China
出 版 物:《Virologica Sinica》 (中国病毒学(英文版))
年 卷 期:2024年第39卷第1期
页 面:24-30页
核心收录:
学科分类:0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
基 金:supported by the Deutsche Forschungsgemeinschaft(RTG1949/2) the National Natural Science Foundation of China(82202497)
主 题:Amphisome Autophagy Endosomal vesicle Hepatitis B virus(HBV)
摘 要:Hepatitis B virus(HBV)produces and releases various particle types,including complete virions,subviral particles with envelope proteins,and naked *** studies demonstrate that HBV exploits distinct intracellular membrane trafficking pathways,including the endosomal vesicle trafficking and autophagy pathway,to assemble and release viral and subviral ***,we summarize the findings about the distinct roles of autophagy and endosomal membrane trafficking and the interaction of both pathways in HBV replication,assembly,and release.