检索结果-南通市图书馆

Journal of Mountain Science 2020年第5期17卷 1106-1114页

作者： XIAO Yuan-ming yang Lu-cun NIE xiu-qing LI Chang-bin XIONG feng ZHOU Guo-ying Northwest Institute of Plateau Biology Chinese Academy of SciencesXining 810008China Key Laboratory of Tibetan Medicine Research Chinese Academy of SciencesXining 810008China qinghai Key Laboratory of qinghai-Tibet Plateau Biological Resources Xining 810008China University of Chinese Academy of Sciences Beijing 100049China

Biodiversity distribution patterns are a basic and long-standing but crucial aspect of ecology *** patterns form the primary source of data used to develop biodiversity protection practices,especially in mountain *** comprise one of the main types of vegetation on the qinghai–Tibetan Plateau,where they serve vital ecological *** this study,we used a community phylogenetic approach to examine the distribution patterns of shrub communities along the longitudinal and latitudinal gradients on the northeastern qinghai–Tibetan *** observed significant latitudinal trends in both the phylogenetic diversity(PD)and net relatedness index(NRI)values of shrub communities,such that the former decreased and the latter increased with increasing ***,no significant PD,NRI and nearest taxon index(NTI)distribution patterns were observed along a longitudinal gradient.A further analysis revealed that the combination of temperature-related and precipitation-related climate variables most strongly affected the PD,NRI and NTI values of shrub communities,indicating that the latitudinal patterns in the PD,NRI and NTI of a shrub community may be determined mainly by interactions with these climate factors.

关键词： Phylogenetic diversity Phylogenetic community structure Shrub communities qinghai–Tibetan Plateau Net Relatedness Index Nearest Taxon Index

Aboveground biomass of the alpine shrub ecosystems in Three-River Source Region of the Tibetan Plateau

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2018年第2期15卷 357-363页

作者： NIE xiu-qing yang Lu-cun XIONG feng LI Chang-bin LI FAN ZHOU Guo-ying Key Laboratory of Tibetan Medicine Research Northwest Institute of Plateau Biology Chinese Academy of Science Xining 810008 China qinghai Key Laboratory of qing-Tibet Plateau Biological Resources Xining 81008 China University of Chinese Academy of Sciences Beijing 100049 China Institute of qinghai Meteorological Science Research Xining 810001 China

Though aboveground biomass(AGB) has an important contribution to the global carbon cycle,the information about storage and climatic effects of AGB is scare in Three-River Source Region(TRSR)shrub ecosystems. This study investigated AGB storage and its climatic controls in the TRSR alpine shrub ecosystems using data collected from 23 sites on the Tibetan Plateau from 2011 to 2013. We estimated the AGB storage(both shrub layer biomass and grass layer biomass) in the alpine shrubs as 37.49 Tg, with an average density of 1447.31 g m^(-2). Biomass was primarily accumulated in the shrub layer, which accounted for 92% of AGB, while the grass layer accounted for only 8%. AGB significantly increased with the mean annual temperature(P he effects of the mean annual precipitation on AGB were not significant. These results suggest that temperature,rather than precipitation, has significantly effects on of aboveground vegetation growth in the TRSR alpine shrub ecosystems. The actual and potential increase in AGB density was different due to global warming varies among different regions of the TRSR. We conclude that long-term monitoring of dynamic changes is necessary to improve the accuracy estimations of potential AGB carbon sequestration across the TRSR alpine shrub ecosystems.

关键词： Alpine shrub ecosystem Abovegroundbiomass Temperature Precipitation Sanjiangyuan Three-River Source Region

Exogenous Nitric Oxide Alleviated the Inhibition of Photosynthesis and Antioxidant Enzyme Activities in Iron-Deficient Chinese Cabbage (Brassica chinensis L.)

在线全文

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2008年第2期7卷 168-179页

作者： DING Fei WANG xiu-feng SHI qing-hua WANG Mei-ling yang feng-juan GAO qing-hai State Key Laboratory of Crop Biology College of Horticulture Science and Engineering Shandong Agricultural University Tai＇an 271018 P.R. China

The effects of exogenous nitric oxide （NO） on plant growth, chlorophyll contents, photosynthetic and chlorophyll fluorescence parameters as well as lipid peroxidation and activities of antioxidant enzymes were investigated in Chinese cabbage plants exposed to iron （Fe） deficiency. Iron deficiency led to serious chlorosis in Chinese cabbage leaves, and resulted in significant decrease in plant growth, photosynthetic pigments, net photosynthetic rate, Fv/Fm, Ф ps Ⅱ and activities of antioxidant enzymes, and increase in lipid peroxidation. While treatment with SNP, a NO donor, it could revert the iron deficiency symptoms, increased photosynthetic rate as well as activities of antioxidant enzymes, and protected membrane from lipid peroxidation, as a result, the growth inhibition of Chinese cabbage by Fe deficiency was alleviated.

关键词： antioxidant enzyme Chinese cabbage iron deficiency nitric oxide photosynthesis

A new method for concentration analysis of bacterial endotoxins in perfluorocarbon

在线全文

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2014年第4期8卷 399-402页

作者： Dan-Dan CheN Xiao-Ming feng Chun-Ren WANG qing-quan HUANG Zhao-Peng yang qing-Yuan MENG National Institutes for Food and Druq Control Beijing 100050 China School of Materials Science and Engineering Tsinghua University Beijing 100084 China

This communication demonstrates the feasibility of the gel-clot method for the analysis of bacterial endotoxins in water extracts of perfluorocarbon which is a water insoluble liquid medical device. Perfluorocarbon （10 mL） was shaken with 10 mL water for 15 min at 2000 r/min and the endotoxin present was extracted to the aqueous phase without interference inhibition/enhancement of the product and the recovery of endotoxin added to perfluorocarbon was determined, A validation study confirmed that endotoxins presented in perfluorocarbon pass over into the aqueous phase at concentrations of 20, 10 and 5EU/mL with recoveries from 86.8% to 96.8%. Therefore, the gel-clot test is suitable for detecting bacterial endotoxins in perfluorocarbon which is a water insoluble medical device.

关键词： perfluorocarbon bacterial endotoxin endotoxin recovery

Down-regulation of Vinculin in Human Colorectal Carcinoma Identified by Proteomics Analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2012年第6期28卷 1031-1034页

作者： yang Guang-yuan ZHAO Hai-feng XIE feng LI Yi SUN Li SHI qing-hong he Cheng-yan LIU Ning SONG Li-na China-Japan Union Hospital of Jilin University Changchun 130033 P. R. China The First Affiliated Hospital of Jiamusi University Jiamusi 154003 P. R. China The Second Hospital of Jilin University Changchun 130021 P. R. China Stomatological School of Jilin University Changchun 130021 P. R. China

In the present study,we aimed to globally profile the proteins involved in colorectal carcinoma（CRC）,in order to find clues to the pathological process of *** of malignant tissues and their adjacent healthy tissues from patients with colorectal cancer were subject to differential proteomics *** dimensional electrophoresis coupled with mass spectrometry（2-DE/MS） was used to identify differentially expressed proteins between pairs of tissue samples.A list of proteins relevant to the progression of colorectal tumor was identified by two dimensional gel electrophoresis（2-DE）-based proteomics *** the identified proteins,vinculin was found to be remarkably down-regulated in colorectal carcinoma *** addition,three phosphorylation modifications within the isolated vinculin were identified by in-depth liquid chromatography-tandem mass spectrometry（LC-MS/MS） *** results provide a basis for further understanding the pathological significance of vinculin in the regulation of carcinogenesis,invasion and metastasis of colorectal tumors.

关键词： Mass spectrometry Vinculin Colorectal carcinoma Phosphorylation

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第5期18卷 1067-1075页

作者： Xin Sun Li-Yi Huang hong-Xia Pan Li-Juan Li Lu Wang Gai-Qin Pei yang Wang qing Zhang hong-Xin Cheng Cheng-Qi he quan Wei Rehabilitation Medical Center and Institute of Rehabilitation Medicine West China HospitalSichuan UniversityChengduSichuan ProvinceChina Key Laboratory of Rehabilitation Medicine in Sichuan Province ChengduSichuan ProvinceChina

Although many therapeutic interventions have shown promise in treating spinal cord injury, focusing on a single aspect of repair cannot achieve successful and functional regeneration in patients following spinal cord injury. In this study, we applied a combinatorial approach for treating spinal cord injury involving neuroprotection and rehabilitation, exploiting cell transplantation and functional sensorimotor training to promote nerve regeneration and functional recovery. here, we used a mouse model of thoracic contusive spinal cord injury to investigate whether the combination of bone marrow mesenchymal stem cell transplantation and exercise training has a synergistic effect on functional restoration. Locomotor function was evaluated by the Basso Mouse Scale, horizontal ladder test, and footprint analysis. Magnetic resonance imaging, histological examination, transmission electron microscopy observation, immunofluorescence staining, and western blotting were performed 8 weeks after spinal cord injury to further explore the potential mechanism behind the synergistic repair effect. In vivo, the combination of bone marrow mesenchymal stem cell transplantation and exercise showed a better therapeutic effect on motor function than the single treatments. Further investigations revealed that the combination of bone marrow mesenchymal stem cell transplantation and exercise markedly reduced fibrotic scar tissue, protected neurons, and promoted axon and myelin protection. Additionally, the synergistic effects of bone marrow mesenchymal stem cell transplantation and exercise on spinal cord injury recovery occurred via the PI3 K/AKT/mTOR pathway. In vitro, experimental evidence from the PC12 cell line and primary cortical neuron culture also demonstrated that blocking of the PI3 K/AKT/mTOR pathway would aggravate neuronal damage. Thus, bone marrow mesenchymal stem cell transplantation combined with exercise training can effectively restore motor function after spinal cord inj

关键词： axon growth bone marrow mesenchymal stem cell exercise training mTOR neuroprotection neurotrophin remyelination scar formation spinal cord injury synaptic plasticity

^(18)F-PBR06 PET/CT imaging of inflammation and differentiation of lung cancer in mice

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2019年第5期30卷 122-129页

作者： he Zhang Hui Tan Wu-Jian Mao Jun Zhou Zhe-quan Fu Yan Hu Jie Xiao qing-Yu Lin hong-Cheng Shi Deng-feng Cheng Shanghai Institute of Medical Imaging Department of Nuclear Medicine Zhongshan HospitalFudan University Institute of Nuclear Medicine Fudan University

The present study explored the 18-kDa translocator protein radioligand ^(18)F-PBR06 as a PET imaging biomarker for diagnosis of inflammation and compared it with ^(18)F-FDG for differentiation of inflammation and lung tumors in animals.^(18)F-PBR06 was synthesized with an average decay-corrected radiochemical yield of 30–40%(end of synthesis, EOS), and the radiochemical purity was greater than 99%. The inflammation-to-blood ratio of ^(18)FPBR06(3.53 ± 0.26) was higher than the tumor-to-blood ratio(1.77 ± 0.35)(P \ 0.001). The inflammation-tomuscle ratio of ^(18)F-PBR06(2.33 ± 0.64) was also higher than the tumor-to-muscle ratio(1.45 ± 0.14)(P = 0.036).Micro-PET/CT images showed high uptake of ^(18)F-FDG in both inflamed muscles and lung tumor tissues. However,^(18)F-PBR06 uptake in inflamed muscles remained higher than that in the lung tumor tissues, following 90 min of dynamic Micro-PET/CT imaging. Further, macrophages in the inflammatory regions showed a higher fluorescence signal than in lung tumor tissues. Results of the study confirmed that ^(18)F-PBR06 PET/CT imaging allowed for diagnosis of inflammation. Moreover,^(18)F-PBR06 uptake in the inflammatory regions was significantly higher than in lung tumor tissues, suggesting that ^(18)F-PBR06 PET/CT imaging has potential to differentiate between peripheral lung cancer and inflammation nodules.

关键词： TSPO Macrophage PET/CT Inflammation Lung cancer

The RNAome landscape of tomato during arbuscular mycorrhizal symbiosis reveals an evolving RNA layer symbiotic regulatory network

在线全文

学校读者我要写书评

暂无评论

Plant Communications 2023年第1期4卷 148-166页

作者： Zhen Zeng yang Liu xing-Yu feng Sai-Xi Li xing-Mei Jiang Jian-Qun Chen Zhu-qing Shao State Key Laboratory of Pharmaceutical Biotechnology School of Life SciencesNanjing UniversityNanjing 210023China

Arbuscular mycorrhizal symbiosis(AMS)is an ancient plant-fungus relationship that is widely distributed in terrestrial *** formation of symbiotic structures and bidirectional nutrient exchange requires the regulation of numerous ***,the landscape of RNAome during plant AMS involving different types of regulatory RNA is poorly *** this study,a combinatorial strategy utilizing multiple sequencing approaches was used to decipher the landscape of RNAome in tomato,an emerging AMS *** annotation of the tomato genome was improved by a multiple-platform sequencing strategy.A total of 3,174 protein-coding genes were upregulated during AMS,42%of which were alternatively ***-transcriptome analysis revealed that genes from 24 orthogroups were consistently induced by AMS in eight phylogenetically distant *** additional orthogroups were specifically induced by AMS in all surveyed dicot AMS host ***,these orthogroups were absent or not induced in monocots and/or non-AMS hosts,suggesting a continuously evolving AMS-responsive network in addition to a conserved core regulatory ***,we detected 587 lncRNAs,ten miRNAs,and 146 circRNAs that responded to AMS,which were incorporated to establish a tomato AMSresponsive,competing RNA-responsive endogenous RNA(ceRNA)***,a tomato symbiotic transcriptome database(TSTD,https://***/TSTD)was constructed to serve as a resource for deep deciphering of the AMS regulatory *** results help elucidate the reconfiguration of the tomato RNAome during AMS and suggest a sophisticated and evolving RNA layer responsive network during AMS processes.

关键词： tomato RNAome landscape arbuscular mycorrhizal symbiosis evolution ceRNA network

Aberrant expression of genes and proteins in pterygium and their implications in the pathogenesis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2017年第6期10卷 973-981页

作者： qing-yang feng Zi-Xuan Hu Xi-Ling Song hong-Wei Pan[[ Department of Ophthalmology the First Affiliated Hospital of Jinan University Guangzhou 510630 Guangdong Province China Department of Public health and Preventive Medicine Jinan University Guangzhou 510632 Guangdong Province China Institute of Ophthalmology School of Medicine Jinan University Guangzhou 510632 Guangdong Province China

Pterygium is a common ocular surface disease induced by a variety of factors. The exact pathogenesis of pterygium remains unclear. Numbers of genes and proteins are discovered in pterygium and they function differently in the occurrence and development of this disease. We searched the Web of Science and PubMed throughout history for literatures about the subject. The keywords we used contain pterygium, gene, protein, angiogenesis, fibrosis, proliferation, inflammation, pathogenesis and therapy. In this review, we summarize the aberrant expression of a range of genes and proteins in pterygium compared with normal conjunctiva or cornea, including growth factors, matrix metalloproteinases and tissue inhibitors of mefalloproteinases, interleukins, tumor suppressor genes, proliferation related proteins, apoptosis related proteins, cell adhesion molecules, extracellular matrix proteins, heat shock proteins and tight junction proteins. We illustrate their possible mechanisms in the pathogenesis of pterygium as well as the related intervention based on them for pterygium therapy.

关键词： pterygium growth factors matrixmetalloproteinases tissue inhibitors of metalloproteinases interleukins tumor suppressor genes proliferation andapoptosis cell adhesion molecules extmcellular matrix proteins

Warthin-like papillary renal cell carcinoma: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第30期11卷 7450-7456页

作者： xiu-feng Li Zheng-Jiang Wang heng-Ming Zhang Mai-qing yang Department of Pathology Weifang People's Hospital(First Affiliated Hospital of Weifang Medical University)Weifang 261041Shandong ProvinceChina

BACKGROUND Warthin-like papillary renal cell carcinoma(WPRCC)has been described as a rare pathological subtype of papillary renal cell carcinoma in the 2022 World health Organization Classification of the Urinary and Male Reproductive *** we report a case of WPRCC in the left *** SUMMARY Physical examination of a previously healthy 47-year-old woman revealed a lump in her left kidney,4.5 cm×3.5 cm×3.5 cm in *** on the clinical information,imaging data,histmorphological features,and immunohistochemistry results,the pathological diagnosis was WPRCC in left *** Resection of the mass in the left kidney was performed and her postoperative course was uneventful.

关键词： Papillary renal cell carcinoma Warthin-like Clinicopathologic features Case report