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桦褐孔菌品质鉴定及抗氧化活性研究

北华大学学报（自然科学版） 2024年第1期25卷 35-39页

作者：常明珠李亭昱崔云鹤刘腾达郭笑母润红北华大学基础医学院吉林吉林132013 北华大学药学院吉林吉林132013

目的确定桦褐孔菌多糖的最佳提取工艺,并对桦褐孔菌多糖的抗氧化活性进行评价。方法应用水提法、超声法、微波法和酶法分别对桦褐孔菌多糖进行3次提取;以VC为对照,测定桦褐孔菌多糖对FRAP、DPPH·、·OH和ABTS·的还原能力。结果超声法... 详细信息

目的确定桦褐孔菌多糖的最佳提取工艺,并对桦褐孔菌多糖的抗氧化活性进行评价。方法应用水提法、超声法、微波法和酶法分别对桦褐孔菌多糖进行3次提取;以VC为对照,测定桦褐孔菌多糖对FRAP、DPPH·、·OH和ABTS·的还原能力。结果超声法在料液比m(g)∶V(mL)=1∶20、超声功率400 W、提取温度80℃、提取时间90 min时,多糖提取率最高,为10.35%;抗氧化活性研究结果显示,当桦褐孔菌的多糖浓度为400μg/mL时,其总抗氧化能力相当于244.04μmol/L的FeSO 4,对DPPH·的清除率较弱,对·OH和ABTS·的清除率均可达80%以上。结论超声法提取桦褐孔菌多糖效果最好,其抗氧化活性较高。

关键词：桦褐孔菌多糖抗氧化

High‑Performance Flexible Microneedle Array as a Low‑Impedance Surface Biopotential Dry Electrode for Wearable Electrophysiological Recording and Polysomnography

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Nano-Micro Letters 2022年第8期14卷 142-163页

作者： Junshi li Yundong Ma Dong Huang Zhongyan Wang Zhitong Zhang Yingjie Ren Mengyue Hong Yufeng Chen tingyu li Xiaoyi Shi Lu Cao Jiayan Zhang Bingli Jiao Junhua liu Hongqiang Sun Zhihong li National Key Laboratory of Science and Technology on Micro/Nano Fabrication School of Integrated CircuitsPeking UniversityBeijing 100871People’s Republic of China Peking University Sixth Hospital Peking University Institute of Mental HealthNHC Key Laboratory of Mental Health(Peking University)National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital)Beijing 100191People’s Republic of China School of Electronics Peking UniversityBeijing 100871People’s Republic of China Hypnometry Microsystem Beijing 100871People’s Republic of China College of Engineering Peking UniversityBeijing 100871People’s Republic of China

Microneedle array(MNA)electrodes are an effective solution to achieve high-quality surface biopotential recording without the coordination of conductive gel and are thus very suitable for long-term wearable *** schemes are limited by flexibility,biosafety,and manufacturing costs,which create large barriers for wider ***,we present a novel flexible MNA electrode that can simultaneously achieve flexibility of the substrate to fit a curved body surface,robustness of microneedles to penetrate the skin without fracture,and a simplified process to allow mass *** compatibility with wearable wireless systems and the short preparation time of the electrodes significantly improves the comfort and convenience of electrophysiological *** normalized electrode–skin contact impedance reaches 0.98 kΩcm^(2)at 1 kHz and 1.50 kΩcm^(2)at 10 Hz,a record low value compared to previous reports and approximately 1/250 of the standard *** morphology,biosafety,and electrical/mechanical properties are fully characterized,and wearable recordings with a high signal-to-noise ratio and low motion artifacts are *** first reported clinical study of microneedle electrodes for surface electrophysiological monitoring was conducted in tens of healthy and sleep-disordered subjects with 44 nights of recording(over 8 h per night),providing substantial evidence that the electrodes can be leveraged to substitute for clinical standard electrodes.

关键词： Flexible microneedle array Dry electrode Low-impedance electrode–skin contact Wearable wireless electrophysiological recording Polysomnography

A review of low-carbon technologies and projects for the global cement industry

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Journal of Environmental Sciences 2024年第2期136卷 682-697页

作者： Yangyang Guo Lei Luo Tingting liu liwei Hao Yinming li Pengfei liu tingyu Zhu CAS Key Laboratory of Green Process and Engineering Institute of Process EngineeringInnovation Academy for Green ManufactureChinese Academy of SciencesBeijing 100190China Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China State Key Laboratory of Solid Waste Reuse for Building Materials Beijing Building Materials Academy of Sciences ResearchBeijing 100041China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou 341000China

Carbon dioxide(CO_(2))emissions from the cement industry account for 26%of the total industrial emissions,and the need to develop low-carbon techniques within the cement industry is extremely ***-carbon projects and technologies for the cement industry in different regions and countries have been thoroughly reviewed in this manuscript,and the low-carbon development concept for each county has been *** developing countries such as China and India,energy saving and efficiency enhancement are currently the key points,while for developed countries and regions such as Europe,more efforts have been focused on carbon capture,utilization,and storage(CCUS).Global CCUS projects have been previously conducted,and the majority of CCUS projects are currently performed in Europe where major projects such as the CEMCAP,CLEANKER,and IEILAC projects represent the latest research progress in cement production technologies and low-carbon technologies for the global cement *** development of low-carbon cement technologies has changed from focusing on the end point to instead focusing on the source and process through the exploration of hydrogen and solar energies,and more disruptive and original technologies are expected to be developed,particularly in the cement industry in China.

关键词： Cement industry CO_(2)emissions Low carbon development Projects Carbon capture utilization and storage

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湖南省公路固废物质流分析与产排预测

公路工程 2024年第3期49卷 178-185页

作者：贺春宁李婷玉郅晓陈宇亮邓鹏肖源杰湖南省交通科学研究院有限公司湖南长沙410114 中国建材集团有限公司北京100020 湖南大学土木工程学院湖南长沙410082 中南大学土木工程学院湖南长沙410075

为助力公路系统建养生态化、绿色化转型发展,基于公路里程存量与大中修数据,结合MATLAB、Origin等数据分析和处理平台,采用物质流分析方法进行了湖南省公路固废的物质流分析,构建了公路固废产排预测模型。物质流分析结果显示,近年湖南... 详细信息

为助力公路系统建养生态化、绿色化转型发展,基于公路里程存量与大中修数据,结合MATLAB、Origin等数据分析和处理平台,采用物质流分析方法进行了湖南省公路固废的物质流分析,构建了公路固废产排预测模型。物质流分析结果显示,近年湖南省地方公路固废主要为废旧水泥混凝土,占比75%左右,其余为沥青路面回收料(RAP)。高速公路则以RAP为主,占比76%左右,其余为废旧水泥混凝土。在产排预测方面,本文设置短寿命(6 a)、中寿命(10 a)、中长寿命(20 a)和长寿命(30 a)4种寿命情景进行分析,预测了湖南省公路固废产生量的变化规律。结果表明,湖南省地方公路存量和高速公路存量分别在2031年和2050年达到饱和,为451 137 km和11 180 km。短寿命情景下的地方公路和高速公路大中修里程分别于2028年和2022年左右达到峰值,为3 210 km和534 km,长寿命情景下大中修里程的峰值出现更晚、波动更大。在短寿命、中寿命、中长寿命和长寿命4种情景下,地方公路公路固废产生量在2028年、2029年、2037年和2046年达到第一个小峰值,分别为652万t、447万t、291万t和280万t,此后围绕峰值波动;高速公路公路固废产生量在2022年、2024年、2032年和2043年达到第一个小峰值,分别为238万t、183万t、140万t、110万t,此后围绕峰值波动。结合调研结果,短寿命情境下更加符合湖南省公路固废产生量的实际情况,这意味着我国公路已经进入了大中修的高峰期。

关键词：公路工程产生量预测物质流分析公路固废存量-流量

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乳腺纤维瘤病2例并文献复习

甘肃医药 2024年第1期43卷 84-86页

作者：何欣李婷玉何乐杨楠刘凤磊李晓琴王登科甘肃省肿瘤医院甘肃兰州730050 甘肃中医药大学第一临床医学院甘肃兰州730000 甘肃省人民医院甘肃兰州730000

乳腺纤维瘤病是一种纤维组织来源的交界性肿瘤,临床少见,以浸润生长和局部复发为主要特点,但不易发生远处转移,易误诊为乳腺癌。乳腺纤维瘤病的明确诊断必须通过组织病理学检查,并且要与乳腺其他的梭形细胞病变进行鉴别。本文通过回顾... 详细信息

乳腺纤维瘤病是一种纤维组织来源的交界性肿瘤,临床少见,以浸润生长和局部复发为主要特点,但不易发生远处转移,易误诊为乳腺癌。乳腺纤维瘤病的明确诊断必须通过组织病理学检查,并且要与乳腺其他的梭形细胞病变进行鉴别。本文通过回顾性分析我院收治的2例乳腺纤维瘤病患者的临床资料,从乳腺纤维瘤病的病理形态、免疫表型特征、鉴别诊断及临床特点方面进行探讨,以加深对该病的认识。

关键词：乳腺肿瘤纤维瘤病诊断鉴别诊断

Ultrathin curved PdNiRu nanosheets as bifunctional catalysts for oxygen reduction and ethylene glycol oxidation

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Nano Research 2024年第5期17卷 3777-3784页

作者： Xianzeng li tingyu Lu Huan Pang Mingyi Zhang Dongdong Xu lin Xu Min Han Jun Yang Jiangsu Key Laboratory of New Power Batteries Jiangsu Collaborative Innovation Center of Biomedical Functional MaterialsSchool of Chemistry and Materials ScienceNanjing Normal UniversityNanjing 210023China Fujian Cross Strait Institute of Flexible Electronics(Future Technology) Fujian Normal UniversityFuzhou 350117China State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China State Key Laboratory of Coordination Chemistry Nanjing UniversityNanjing 210023China School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225009China Key Laboratory for Photonic and Electronic Bandgap Materials Ministry of EducationSchool of Physics and Electronic EngineeringHarbin Normal UniversityHarbin 150025China

Pd-based metallic nanosheets with advanced physicochemical properties have been widely prepared and employed in various electrocatalytic ***,few concerns were focused on their multiple performances in different ***,highly curved and ultrathin PdNiRu nanosheets(NSs)are developed by facile wet-chemistry strategy and exhibit excellent electrocatalytic performance toward both oxygen reduction reaction(ORR)and ethylene glycol oxidation reaction(EGOR).Owing to the synergistically structural(e.g.,ultrathin,curved,defects/steps-rich)and compositional(ternary alloy)advantages,PdNiRu NSs exhibited enhanced ORR and EGOR specific/mass activities and better stability/durability than control *** specific activity(5.52 mA·cm^(−2))and mass activity(1.13 A·mg_(Pd)^(−1))of the PdNiRu NSs in ORR are 4.8 and 3.4 times as the ones of commercial Pt/C,*** mass activity of PdNiRu NSs(3.86 A·mg_(Pd)^(−1))in EGOR is 2.6 times as commercial Pd/C(1.51 A·mg_(Pd)^(−1)).This study is helpful for the development of desired electrocatalysts with multi-functional application in practical fuel cells.

关键词： ultrathin nanosheets noble metal electrocatalysts bifunctional

Dedifferentiated human umbilical cord mesenchymal stem cell reprogramming of endogenous hSDF-1a expression participates in neural restoration in hypoxic-ischemic brain damagerats

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Genes & Diseases 2021年第3期8卷 331-343页

作者： Zhou Xiaoqin liu Jia Dai Mengjie Gu Jialu Bi Yang Wang Yuting Hu Huajian liu Bo Zhang Xiaojun li Zhongyue Chen Jie li tingyu Zhan Xue Department of Gastroenterology Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and Disorders(Chongqing)401122PR China International Science and Technology Cooperation Base of Child Development and Critical Disorders Children’sHospital of Chongqing Medical UniversityChongqing401122PR China Department of Pediatric Research Institute Chongqing Key Laboratory of Child Health and NutritionChildren’s Hospital of Chongqing Medical UniversityChongqing401122PR China Department of Neonatology Chongqing Health Center for Womenand Children400021PR China Child Health Centre of Northwest Women and Children’s Hospital USA

The transplantation of human umbilical cord mesenchymal stem cells(hUC-MSCs)can promote hypoxic-ischemic brain damage(HIBD)nerve repair,but finding suitable seed cells to optimize transplantation and improve treatment efficiency is an urgent problem to be *** this study,we induced hUC-MSCs into dedifferentiated hUC-MSCs(De-hUC-MSCs),and the morphology,stem cell surface markers,proliferation and tri-directional differentiation ability of the De-hUC-MSCs and hUC-MSCs were detected.A whole-gene chip was utilized for genome cluster,gene ontology and KEGG pathway analyses of differentially expressed ***-hUC-MSCs were transplanted into HIBD rats,and behavioral experiments and immunofluorescence assays were used to assess the therapeutic effect.A lentivirus vector for human stromal cell-derived factor-1(hSDF-1a)was constructed,and the role of hSDF-1a in the neuroprotective effect and mechanism of De-hUC-MSCs was ***-hUC-MSCs displayed similar cell morphology,stem cell surface marker expression,cell proliferation and even three-dimensional differentiation ability as hUC-MSCs but exhibited greater treatment potential in *** reprogramming mechanism of hSDF-1a participated in the dedifferentiation *** successfully constructing a stable hSDF-1a cell line,we found that De-hUC-MSCs might participate in nerve repair through the hSDF-1a/CXCR4/PI3K/Akt ***-hUC-MSCs reprogramming of endogenous hSDF-1a expression may mediate the hSDF-1a/CXCR4/PI3K/Akt pathway involved in nerve repair in HIBD rats.

关键词： Dediffer entiation Human umbilicalcord mesenchymal stem cells Hypoxic-ischemic brain damage Neurorestoration Reprogramming Stromal cell-derived factor-1

不同时间催花处理对‘台农17号’菠萝果实品质的影响

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热带生物学报 2024年第3期15卷 323-331页

作者：吴永旺付山梁邺何善林韩泽永姚金双殷涛李婷玉海南大学热带农林学院海南海口570208 海南天地人生态农业股份有限公司海南海口570100

为明确不同时间催花处理对‘台农17号’菠萝果实的产量、品质及关键内源激素的影响,通过大田试验分别于2022年8月及9月中旬进行不同时间催花处理(2.0%电石溶液间隔1 d于夜间灌心3~5 s),统计催花后菠萝的正常果率、植株干物质、产量品质... 详细信息

为明确不同时间催花处理对‘台农17号’菠萝果实的产量、品质及关键内源激素的影响,通过大田试验分别于2022年8月及9月中旬进行不同时间催花处理(2.0%电石溶液间隔1 d于夜间灌心3~5 s),统计催花后菠萝的正常果率、植株干物质、产量品质及内源激素含量等差异。结果表明:9月中旬催花处理菠萝果实成熟时长约比8月中旬催花处理的长30 d;其无冠、多冠等畸形果占比相较8月中旬催花少31.33%;9月中旬催花处理干物质积累量、产量、糖酸比及可溶性蛋白含量分别比8月中旬催花处理提升了6.63%、25.75%、23.73%、50.36%,可滴定酸显著降低了14.71%;不同果型果实的糖组分差异不大,均以蔗糖积累为主;不同时间催花处理对正常果、无冠果实的内源激素都有显著性影响,相较8月中旬催花处理,9月中旬催花处理显著降低了无冠果的赤霉素、脱落酸、反式玉米素含量,分别降低了23.81%、41.67%、17.54%,无冠果茉莉酸含量显著提高了120.93%;显著降低了正常果脱落酸、水杨酸含量,分别降低了18.18%、54.81%,正常果反式玉米素含量显著提高了27.91%。综合分析认为,9月中旬催花的‘台农17号’菠萝果实品质和产量更好。

关键词：菠萝不同时间催花处理品质产量内源激素

Design of artificial biomimetic channels with Na^(+)permeation rate and selectivity potentially outperforming the natural sodium channel

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Nano Research 2024年第9期17卷 8638-8646页

作者： Zhi Zhu Yan Zhao Chao Chang Shaojian Yan tingyu Sun Shiyu Gu Yangmei li Dengsong Zhang Chunlei Wang Xiao Cheng Zeng School of Optical-Electrical and Computer Engineering University of Shanghai for Science and TechnologyShanghai 200093China Innovation Laboratory of Terahertz Biophysics National Innovation Institute of Defense TechnologyBeijing 100071China School of Physics Peking UniversityBeijing 100871China International Joint Laboratory of Catalytic Chemistry College of SciencesShanghai UniversityShanghai 200444China Department of Materials Science and Engineering City University of Hong KongHong Kong 999077China

Artificial ion channels that enable high-efficiency ion transport have important implications in nanofluidics and biomedical applications such as drug ***,we show a simulation-based chemical design of a biomimetic sodium channel that possesses permeation rate and selectivity potentially higher than those of the state-of-the-art natural vertebrate voltage-gated sodium ***,our theoretical findings have undergone empirical testing,aligning well with the Arrhenius law as derived from a diverse range of experimental *** high-efficiency ion transport is achieved by anchoring the carboxylate functional groups within the channel filter.A key chemical guiding principle underlying the ion channel design is that the free-energy barrier for the Na^(+)passage across the channel should be comparable to typical thermal energy at room *** the implementation of the chemical design,we found that the relatively low free-energy barrier can be attributed to the compensation effect of the carboxylate groups to the partially lost oxygen shell of the ion within the ion channel,as well as to the consonant vibration of the ions inside and outside the *** mechanistic understanding brings new insight,at the molecular level,into the high-efficiency ion transport across the designed membrane *** proof of principle achieved from the simulations will stimulate future experimental confirmation and potential applications of the high-performance artificial channels in nanofluidics and in bioinspired iontronics.

关键词： sodium channels anchoring carboxylate functional groups molecular dynamics simulations low free-energy barrier for ion passage thermal kinetic energy