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Molecular Mediators of Estrogen Reduction-induced Otolith Shedding

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Current Medical Science 2021年第4期41卷 667-672页

作者： Mei-yan FENG huan-huan GU Qing TIAN Hua-lan yanG Jian-hua ZhuanG Department of Neurology Medical Center for Vertigo and Balance DisordersShanghai Changzheng Hospital of Navy Medical UniversityShanghai200003China Department of Neurology Shanghai Pudong HospitalFudan University Pudong Medical CenterShanghai201399China

Objective Previous study suggested that estradiol(E2)plays an important role in otolith shedding by regulating the expression of otoconin 90(OC90).The purpose of this article is to provide further data on the effect and mechanism of E2 on the morphology of *** The rats receiving bilateral ovariectomy(OVX)were used as animal ***-immunoprecipitation was used to observe the relationship between estrogen receptor(ER)and estrogen-related receptorα(ERRα).The morphology of otolith was observed under the scanning electron *** blotting and qPCR were used for quantitative analysis of the roles of ER and ERRαin regulating OC90 *** The looser otoliths were observed in rats receiving bilateral OVX,which could be reversed by supplementation with *** level of ERRαwas decreased in bilateral OVX *** and ERRαinteracted with each other on the regulation of the expression of *** Our results suggest ER and ERRαare both important downstream receptors involved in regulating OC90 expression in utricles of rats,and ERRαprobably functions by interacting with *** provides evidence for the mechanism of otolith *** it may be significant for future studies of targeted prevention and therapies for benign paroxysmal positional vertigo.

关键词： estrogen-related receptorα estrogen receptor otoconin 90 otolith benign paroxysmal positional vertigo

Ferroelectric-like behaviors of metal-insulator-metal with amorphous dielectrics

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Science China(Information Sciences) 2023年第10期66卷 178-183页

作者： huan LIU Jiajia CHEN Chengji JIN Xiao YU yan LIU Genquan HAN Research Center for Intelligent Chips Zhejiang Lab School of Microelectronics Xidian University

In this paper, unique ferroelectric-like characteristics in amorphous(a-) ZrO2-based devices enabled by mobile ions are systematically investigated at room temperature and cryogenic. The physical origin of the ferroelectric-like behaviors of the metal/a-ZrO2/metal capacitor is confirmed to be the migration of ions exhibiting strong frequency dependency due to the limited velocity of the mobile ions, which is proven by the comparison between experimental results and theoretical analysis. The ferroelectric-type hysteresis will be reduced sharply with the decrease of the temperature, which is essentially different from the reported doped-HfO2FeFET. This further confirms that the origin of the ferroelectric-like characteristics is the migration and redistribution of the mobile ions.

关键词： ferroelectric-like mobile ion amorphous dielectric ZrO$_{2}$ temperature

Transmission Properties of One-Dimensional Photonic Crystals Containing Anisotropic Metamaterials

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Chinese Physics Letters 2010年第6期27卷 93-96页

作者： ZHANG Li-Wei yan Ling-Ling ZHAO Yu-huan LIU Li School of Physics and Chemistry Henan Polytechnic University Jiaozuo 454000 Pohl Institute of Solid State Physics Tongji University Shanghai 200092

The transmission properties of one-dimensional photonie crystals （1DPCs） containing anisotropic metamaterials are theoretically studied. It is shown that the 1DPCs can possess a similar zero average index （zero-n） gaps, the edges of zero-~ gap are weakly dependent on the incident angles, scale length and the polarization of the electromagnetic wave. When an impurity is introduced, a defect mode appears inside the zeron gap with a very weak dependence on incident angles and sealing. It is found that in such photonic crystals, a transmitted Gaussian pulse with its carrier frequency lying in the lower gap edge, in the defect mode and in the bandgap, can experience a positive or negative group delay and hence a subluminal, *** or superluminal propagation with small distortions. These properties of the photonic crystals have potential applications in the transfer of information.

关键词： CRYSTAL optics ANISOTROPY METAMATERIALS POLARIZATION of electromagnetic waves SCALING laws (Statistical physics) POINT defects GAUSSIAN processes ENERGY gaps (Physics)

Highly improved hydrogen storage dynamics of nanocrystalline and amorphous NdMg12-type alloys by mechanical milling

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Journal of Iron and Steel Research International 2020年第10期27卷 1236-1246页

作者： Ying-chun Liu yan Qi Wei Zhang Jin-liang Gao yang-huan Zhang China National Institute of Standardization Beijing 100191China Department of Functional Material Research.Central Iron and Steel Research Institute Beijing 100081China Weishan Cisri Rare Earth Materials Co. Ltd.Jining 277600ShandongChina

To improve the hydrogenation and dehydrogenation dynamics of NdMg12-type alloy,we replaced part of Mg with Ni in thesamples and used the ball milling method to prepare NdMg11Ni+x wt.%Ni(x=100,200)*** infuences of millingduration and Ni content on the electrochemical and gascous dynamics of the samples were studied in ***-tion activation cnergies of samples were calculated by using Kissinger and Arrhenius *** conclusions show thatthe dynamic properties of samples are significantly enhanced with the increase in Ni *** the change of the miling duration,the gaseous hydrogenation rate and high rate discharging capability reach the maximal ***,thedehydrogenation dynamics of sample alloys are always enhanced with the prolonging of milling *** concretely,prolonging milling duration from 5 to 60 h improves the dehydrogenation ratio of NdMgNi+100 wt.%Ni alloy from58.03%to 64.81%and that of NdMgNi+200 wt.%Ni alloy from 62.20%to 71.59%.Besides,the enhancement of gaseoushydrogen storage dynamics of the samples is believed to be the result of the declined dehydrogenation activation energyresulted from the increase in milling duration and Ni content.

关键词： NdMg12 alloy Hydrogen storage dynamics Activation energy Mechanical milling Ni addition

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世界油料贸易网络演化特征及其影响因素

热带地理 2022年第8期42卷 1241-1252页

作者：李爽闫欢东北农业大学经济管理学院哈尔滨150030

基于UN Comtrade公布的2011—2020年国际油料贸易数据,采用复杂网络分析法,研究世界油料贸易网络的演化特征,并通过QAP模型探究油料贸易网络的影响因素。结果表明:1)油料贸易网络具有良好的连通性和小世界属性,但整体网络密度及互惠系... 详细信息

基于UN Comtrade公布的2011—2020年国际油料贸易数据,采用复杂网络分析法,研究世界油料贸易网络的演化特征,并通过QAP模型探究油料贸易网络的影响因素。结果表明:1)油料贸易网络具有良好的连通性和小世界属性,但整体网络密度及互惠系数相对较低,网络中各节点间的联系有待加强;国际油料出口市场高度集中,进口市场相对分散,贸易重心向以巴西为首的发展中经济体偏移;油料贸易网络存在核心―半边缘―边缘的圈层结构,核心成员国家主要集中在北美和南美地区,美国、巴西和阿根廷是主要的核心国家,对其他国家存在较强的影响力。2)经济规模差异、人均收入差异、人均耕地面积差异和陆地接壤对油料贸易具有显著的正向影响;制度距离和劳动力数量差异则存在显著的负向影响;地理距离在无权网络中与油料贸易负相关,而在加权网络中为正相关。中国虽是油料进口大国和消费大国,但油料进口来源过度集中,进口潜在风险较大。中国应调整油料进口国别结构,构建油料供应网络,深化贸易合作与利益融合,保障油料进口安全。

关键词：世界油料贸易贸易网络复杂网络 QAP模型影响因素

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Multi-verse optimizer based parameters decision with considering tool life in dry hobbing process

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Advances in Manufacturing 2021年第2期9卷 216-234页

作者： Heng-Xin Ni Chun-Ping yan Shen-Fu Ni huan Shu Yu Zhang State Key Laboratory of Mechanical Transmission Chongqing UniversityChongqing 400030People’s Republic of China Hefei Meiya Photoelectric Technology Co.Ltd Hefei 230088People’s Republic of China

Dry hobbing has received extensive attention for its environmentally friendly processing *** to the absence of lubricants,hobbing process is highly dependent on process parameters combination since using unreasonable parameters tends to affect the machining ***,the consideration of tool life is frequently ignored in gear ***,to settle the above issues,a multiobjective parameters decision approach considering tool life is ***,detailed quantitative analysis between process parameters and hobbing performance,i.e.,machining time,production cost and tool life is ***,a multi-objective parameters decision-making model is constructed in search for optimum cutting parameters(cutting velocity v,axial feed rate f_(a))and hob parameters(hob diameter d_(0),threads z_(0)).Thirdly,a novel algorithm named multi-objective multi-verse optimizer(MOMVO)is utilized to solve the presented model.A case study is exhibited to show the feasibility and reliability of the proposed *** results reveal that(i)a balance can be achieved among machining time,production cost and tool life via appropriate process parameters determination;(ii)optimizing cutting parameters and hob parameters simultaneously contributes to optimal objectives;(iii)considering tool life provides usage precautions support and process parameters guidance for practical machining.

关键词： Process parameters Decision-making Tool life Dry hobbing Multi-objective multi-verse optimizer(MOMVO)

Protonated-amino-functionalized bamboo hydrochar for efficient removal of hexavalent chromium and methyl orange

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Progress in Natural Science:Materials International 2023年第4期33卷 501-507页

作者： Zi-Le Chen huan Xu Li-Qun Bai yan-Long Feng Bing Li College of Chemistry and Materials Engineering Zhejiang A&F University

Hydrochar has great potential for wastewater treatment and the functional modification can significantly improve the ability of hydrochar to remove pollutants. Herein, a novel protonated amino-modified bamboo hydrochar(PAHC) was synthesized by the reaction of bamboo hydrochar first with acryloyl chloride, then with amine and finally with hydrochloric acid, and employed to adsorb methyl orange(MO) and Cr(Ⅵ). The PAHC was observed by BET, SEM-EDX, FTIR, elemental analysis, and zeta potential to monitor its textural properties before and after adsorption. The amino groups were effectively grafted onto the hydrochar by the Aza-Michael addition reaction through characterization. Adsorption results showed the PAHC possessed high MO/Cr(Ⅵ) adsorption amounts(515.35/523.57 mg g-1at 298 K) because the introduction of protonated amine was pivotal in eliminating anionic pollutants by electrostatic interaction. The Langmuir/Freundlich model can well describe MO/Cr(Ⅵ)adsorption, which proves the removal process belongs to MO monolayer/Cr(Ⅵ) multilayer adsorption. The PAHC also exhibited a good regeneration performance. These results indicate the PAHC is a green and efficient adsorbent with potential application in wastewater treatment.

关键词： Methyl orange Cr(VI) Hydrochar Adsorption Modification

High mobility germanium-on-insulator p-channel FinFETs

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Science China(Information Sciences) 2021年第4期64卷 241-242页

作者： huan LIU Genquan HAN Jiuren ZHOU yan LIU Yue HAO State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology School of MicroelectronicsXidian University

Dear editor,Over the past decade, germanium has attracted great interest as a promising channel material for p-channel metal oxide semiconductor field-effect-transistor (MOSFET), owing to its higher hole mobility over... 详细信息

关键词： Information Systems and Communication Service

Characterization of eating quality and starch properties of two Wx alleles japonica rice cultivars under different nitrogen treatments

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Journal of Integrative Agriculture 2020年第4期19卷 988-998页

作者： huanG shuang-jie ZHAO Chun-fang ZHU Zhen ZHOU Li-hui ZHENG Qing-huan WANG Cai-lin Institute of Food Crops Jiangsu Academy of Agricultural Sciences/Jiangsu High Quality Rice R&D Center/Nanjing Branch of China National Center for Rice ImprovementNanjing 210014P.R.China College of Tea Science Xinyang Agriculture and Forestry UniversityXinyang 464000P.R.China Agri-Tech Extension Center of Wancheng District Nanyang 473000P.R.China

To understand the effect of nitrogen(N) fertilizer on rice(Oryza sativa L.) eating and cooking quality(ECQ). Here, we investigated the ECQ attributes, physicochemical foundation of ECQ, and amylopectin fine structure of two Waxy(Wx) alleles japonica rice cultivars Nanjing 9108(NJ9108) and Huaidao 5(HD5) under four N rates(0, 150, 300, and 450 kg ha^-1). Sensory and pasting properties of the two cultivars varied depending on N rates. Compared with the control(0 kg ha^-1), the overall eating quality and sensory value were significantly decreased under the N rates of 300 and 450 kg ha^-1. Further, conventional descriptive analysis showed that the stickiness and retrogradation of cooked rice were significantly decreased. These results indicated that application of N fertilizer seems to affect the texture of cooked rice, causing it to be less sticky, lowering its retrogradation, and consequently reducing its palatability. Results from rapid visco analyzer(RVA) revealed that the peak and breakdown viscosities significantly decreased, while the setback viscosity and peak time increased under the N rates of 300 and 450 kg ha^-1. However, no significant difference was observed when the N rate was 150 kg ha^-1, indicating that less N fertilization can maintain rice ECQ. As the N rate increasing, protein content increased, whereas apparent amylose content, starch content, and gel consistency almost unchanged. Interestingly, compared with the control, under N treatments, the percentage of short amylopectin branches in NJ9108 was decreased, but increased in HD5, as controlled by amylopectin synthesis-related genes. Notably, SSI and BEIIb were down-regulated in NJ9108, whereas BEIIb was up-regulated in HD5. Thus, the palatability of both rice cultivars was significantly decreased under excessive N fertilization as a consequence of reduced stickiness and retrogradation of the cooked rice, which might have resulted from an elevated protein content and altered amylopectin fine struc

关键词： rice(Oryza sativa L.) nitrogen fertilizer eating and cooking quality amylopectin fine structure

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