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Prediction and optimization of flue pressure in sintering process based on SHAP

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 346-359页

作者： Mingyu Wang Jue tang Mansheng Chu Quan shi Zhen Zhang School of Metallurgy Northeastern UniversityShenyang 110819China Liaoning Low-Carbon Steelmaking Technology Engineering Research Center Northeastern UniversityShenyang 110819China Engineering Research Center of Frontier Technologies for Low-Carbon Steelmaking(Ministry of Education) Shenyang 110819China

Sinter is the core raw material for blast *** pressure,which is an important state parameter,affects sinter *** this paper,flue pressure prediction and optimization were studied based on the shapley additive explanation(SHAP)to predict the flue pressure and take targeted adjustment ***,the sintering process data were collected and processed.A flue pressure prediction model was then constructed after comparing different feature selection methods and model algorithms using SHAP+extremely random-ized trees(ET).The prediction accuracy of the model within the error range of±0.25 kPa was 92.63%.SHAP analysis was employed to improve the interpretability of the prediction *** effects of various sintering operation parameters on flue pressure,the relation-ship between the numerical range of key operation parameters and flue pressure,the effect of operation parameter combinations on flue pressure,and the prediction process of the flue pressure prediction model on a single sample were analyzed.A flue pressure optimization module was also constructed and analyzed when the prediction satisfied the judgment *** operating parameter combination was then *** flue pressure was increased by 5.87%during the verification process,achieving a good optimization effect.

关键词： sintering process flue pressure shapley additive explanation prediction optimization

Association between age at diagnosis of diabetes and ocular disease:Insights from a recent article

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World Journal of Diabetes 2025年第1期16卷 211-216页

作者： shi-Qi Liu Dong Wang Cheng-Chun tang Department of Cardiology Zhongda HospitalSoutheast UniversityNanjing 210009Jiangsu ProvinceChina School of Medicine Southeast UniversityNanjing 210009Jiangsu ProvinceChina

In this article,we discuss Ye et al's recent article on the association between age at diabetes diagnosis and subsequent risk of age-related ocular *** study,which utilized United Kingdom Biobank data,highlighted a strong link between early diabetes onset and major eye conditions,such as cataracts,glaucoma,agerelated macular degeneration,and vision loss,independent of glycemic control and disease *** finding challenges the previous belief that diabetic eye disease primarily correlates with *** lifestyles evolve and the age of diabetes diagnosis decreases,understanding this relationship may reveal the complex pathogenesis underlying diabetes-related *** editorial summarizes potential mechanisms connecting the age of diabetes onset with four types of ocular diseases,emphasizing the significance of early diagnosis.

关键词： Diabetes Age at diagnosis Cataract Glaucoma Age-related macular disease Vision acuity

Mixed-charge glycopolypeptides as antibacterial coatings with long-term activity

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Chinese Chemical Letters 2025年第2期36卷 270-278页

作者： Fangping Yang Jin shi Yuansong Wei Qing Gao Jingrui Shen Lichen Yin Haoyu tang Institute of Functional Nano & Soft Materials(FUNSOM) Collaborative Innovation Center of Suzhou Nano Science and TechnologySoochow University

Planktonic bacteria adhere and subsequently form biofilms on implantable medical devices can cause severe infections that have become the major types of hospital-acquired infections. Traditional coatings for the implants are frequently lack of long-term antifouling and bactericidal activities. It is still a big challenge to simultaneously improve the antifouling and bactericidal activities of the coatings. Herein,we report that mixed-charge glycopolypeptide coatings are of long-term antibacterial activities to efficiently inhibit the biofilm growth. The glycosylation of mixed-charge polypeptides has led to a significant improvement of both antifouling and bactericidal activities. The cooperative effect of the saccharide residues and mixed-charge residues improved the resistance of the polypeptide coatings against protein adsorption. The saccharide and L-glutamic acid(E) residues collectively enhanced the bacterial membrane-disruption of cationic L-lysine(K) residues, leading to potent bactericidal activity. Meanwhile,the glycopolypeptide coatings showed superior biocompatibility, long-term antibiofilm and anti-infection properties in two types of mouse subcutaneous infection models and one type of mouse urinary tract infection model. This work provides a new strategy to achieve antibacterial coatings with long-term activities for preventing implantable medical device associated infections.

关键词： Antibacterial coating Bactericidal activity Biofilm Fouling Glycopolypeptide

Sodium citrate enhancing electrodeposition of metallic arsenic from toxic trivalent arsenic and the mechanism understanding

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Journal of Environmental Sciences 2025年第5期151卷 79-87页

作者： Shuiping Zhong Tingyu Xu Hang Chen Ding tang Wen Tan Wei Weng Yanru shi Zijin School of Geology and Mining Fuzhou UniversityFuzhou 350108China Fujian Key Laboratory of Green Extraction and High-value Utilization of New Energy Metals Fuzhou UniversityFuzhou 350108China Zijin Mining Group Co. Ltd.ShanghangLongyan 364200China Inner Mongolia Academy of Science and Technology Hohhot 010010China

Electrochemical conversion of hypertoxic trivalent arsenic to value-added metallic arsenic can not only contribute to pollution abatement,but also resources reutilization,therefore being widely *** reduction of trivalent arsenic as a promising way is widely ***,the high efficiency conversion is retarded by the sluggish reduction kinetics of AsO33−and fierce evolution of side products of both H_(2)and toxic AsH_(3).Herein,by using the sodium citrate as the additive,the current efficiency for metal arsenic production is increased greatly from 60%to 91%,with the accompanied evolution of hypertoxic AsH_(3)being restrained from 0.15 Nm^(3)/t_(As)to 0.022 Nm^(3)/t_(As),promising a high-efficiency and green *** electrochemical tests and electrode surface characterizations aswell as DFT calculations indicate that the added sodium citrate promotes both the diffusion of reactive AsO_(3)^(3−)towards the cathode and its subsequent adsorption on the Ti cathode,contributing to smoother reduction for generating metal arsenic,with the evolution of toxic AsH_(3)being hindered at the same *** results can provide new insights for the highefficiency and greener conversion of hypertoxic trivalent arsenic to value-added metallic arsenic.

关键词： Toxic arsenic Electrochemical conversion Metallic arsenic Sodium citrate

An adjustable bio-sealing method for rock fracture leakage mitigation

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Journal of Rock Mechanics and Geotechnical Engineering 2025年第1期17卷 220-232页

作者： Zhihao Dong Xiaohua Pan Chaosheng tang Chao Lv Bin shi School of Earth Sciences and Engineering Nanjing UniversityNanjing210023China State Key Laboratory for GeoMechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhou221116China

This study proposed a repeated adjustable mixture injection strategy(RAM)based microbial induced carbonate precipitation(MICP)for efficient mitigation of rock fracture *** fractures with small apertures were investigated,and bio-sealing experiments were conducted using five different cementation solution(CS)concentrations(0.25−2 M).The results showed that the RAM-based bio-sealing method can seal and bond the small aperture rock fractures with high efficiency and uniform precipitation by adjusting the CS *** RAM-based bio-sealing mechanism is attributed to the following four stages:(1)fixation of bacterial flocs onto the fracture surfaces,(2)precipitation of CaCO3 onto the fracture surfaces,(3)growth of pre-precipitated CaCO3 and adhesion of new-suspended CaCO3,and(4)bridging and clogging *** optimal CS concentration of 1 M resulted in a fracture filling rate up to 85%,a transmissivity reduction of 4 orders of magnitude,and a shear strength ranging from 512 kPa to 688 *** bio-sealing effect was found to be influenced by the CS concentration on bacterial attachment,calcium carbonate yield and calcium carbonate bulk *** CS concentration of 1 M promoted bacterial attachment,and increased calcium carbonate yield as well as calcium carbonate bulk density,while concentrations above 1 M had the opposite *** bulk density of calcium carbonate played a crucial role in the sealing and bonding performance of bio-sealed fractures,particularly at comparable filling ratios and bridging *** bulk density was regulated by the size of calcium carbonate crystals and was determined by Ca2+concentration in the *** study provides valuable insights into the RAM-based bio-sealing method,highlighting its potential for efficient rock fracture leakage mitigation through precise control of CS concentration and understanding the underlying mechanisms.

关键词： MICP Rock fracture Hydraulic and mechanical performance Bio-sealing

Grading severity of microscopic vascular invasion was independently associated with recurrence and survival following hepatectomy for solitary hepatocellular carcinoma

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Hepatobiliary Surgery and Nutrition 2024年第1期13卷 16-28页

作者： Lan-Qing Yao Chao Li Yong-Kang Diao Lei Liang Hang-Dong Jia shi-chuan tang Yong-Yi Zeng Han Wu Ming-Da Wang Li-Hui Gu Timothy M.Pawlik Wan Yee Lau Cheng-Wu Zhang Feng Shen Kui Wang Tian Yang Department of Hepatobiliary Surgery Eastern Hepatobiliary Surgery HospitalSecond Military Medical University(Navy Medical University)ShanghaiChina Department of General Surgery Cancer CenterDivision of Hepatobiliary and Pancreatic SurgeryZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhouChina Department of Hepatobiliary Surgery Mengchao Hepatobiliary HospitalFujian Medical UniversityFuzhouChina Department of Surgery Ohio State UniversityWexner Medical CenterColumbusOHUSA Faculty of Medicine the Chinese University of Hong KongShatinNew TerritoriesHong KongChina Eastern Hepatobiliary Clinical Research Institute Third Affiliated Hospital of Navy Medical UniversityShanghaiChina

Background:Hepatectomy is the preferred treatment for solitary hepatocellular carcinoma(HCC)without macrovascular invasion and distant metastasis,but long-term survival remains unsatisfactory in certain *** sought to identify whether the grading severity of microscopic vascular invasion(MVI)was associated with recurrence and survival among patients with solitary ***:Consecutive patients who underwent hepatectomy for solitary HCC were identified from a multicenter prospectively-collected *** were categorized into three groups according to the MVI grading system proposed by the Liver Cancer Pathology Group of China:M0(no MVI),M1(1-5 sites of MVI occurring≤1.0 cm away from the tumor),and M2(>5 sites occurring≤1.0 cm or any site occurring>1 cm away from the tumor).Recurrence-free survival(RFS)and overall survival(OS)were compared among the ***:Among 227 patients,97(42.7%),83(36.6%),and 47(20.7%)patients had M0,M1,and M2,*** RFS rates among patients with M0,M1,and M2 were 38.3,35.1,11.6 months,respectively,while OS rates were 66.8,62.3,30.6 months,respectively(both P<0.001).Multivariate Cox-regression analyses demonstrated that both M1 and M2 were independent risk factors for RFS(hazard ratio 1.20,95%CI:1.03-1.89,P=0.040;and hazard ratio 1.67,95%CI:1.06-2.64,P=0.027)and OS(hazard ratio 1.28,95%CI:1.05-2.07,P=0.035;and hazard ratio 1.97,95%CI:1.15-3.38,P=0.013).Conclusions:Grading severity of MVI was independently associated with RFS and OS after hepatectomy for solitary *** surveillance for recurrence and potentially adjuvant therapy may be considered for patients with MVI,especially individuals with more severe MVI grading(M2).

关键词： Hepatocellular carcinoma microscopic vascular invasion recurrence survival hepatectomy

Targeted gene sequencing and bioinformatics analysis of patients with gallbladder neuroendocrine carcinoma:A case report

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 239-251页

作者： Yun-chuan Yang Zhi-Tao Chen Da-Long Wan Hui tang Mu-Lin Liu Department of Medical College Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Department of General Surgery The First Affiliated Hospital of Bengbu Medical UniversityBengbu 233000Anhui ProvinceChina Department of Hepatobiliary Surgery Shulan(Hangzhou)Hospital Affiliated to Zhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Department of Pathology The First Affiliated Hospital of Medical School of Zhejiang UniversityHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Gallbladder neuroendocrine carcinoma(NEC)represents a subtype of gallbladder malignancies characterized by a low incidence,aggressive nature,and poor *** its clinical severity,the genetic alterations,mechanisms,and signaling pathways underlying gallbladder NEC remain *** SUMMARY This case study presents a rare instance of primary gallbladder NEC in a 73-year-old female patient,who underwent a radical cholecystectomy with hepatic hilar lymphadenectomy and resection of liver segments IV-B and *** gene sequencing and bioinformatics analysis tools,including STRING,GeneMANIA,Metascape,TRRUST,Sangerbox,cBioPortal and GSCA,were used to analyze the biological functions and features of mutated genes in gallbladder *** mutations(APC,ARID2,IFNA6,KEAP1,RB1,SMAD4,TP53,BTK,GATA1,GNAS,and PRDM3)were identified,and the tumor mutation burden was determined to be 9.52 muts/Mb via targeted gene sequencing.A protein-protein interaction network showed significant interactions among the twelve mutated *** Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were used to assess mutation functions and *** results revealed 40 tumor-related pathways.A key regulatory factor for gallbladder NEC-related genes was identified,and its biological functions and features were compared with those of gallbladder *** Gallbladder NEC requires standardized *** with other gallbladder carcinomas revealed clinical phenotypes,molecular alterations,functional characteristics,and enriched pathways.

关键词： Gallbladder neuroendocrine carcinoma Targeted-gene sequencing Bioinformatics analysis case report Immunocytochemistry Case report

Intermetallic compounds for nitrogen electrochemistry

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Green Energy & Environment 2025年第2期10卷 268-291页

作者： Haohong Wei Cheng tang Yanyun Wang Yongcheng Feng Huancong shi Mingjin Cui Huakun Liu shixue Dou Laiquan Li Institute of Energy Materials Science School of Energy and Power EngineeringUniversity of Shanghai Science and TechnologyShanghai200093China Tsinghua Center for Green Chemical Engineering Electrification(CCEE) Department of Chemical EngineeringTsinghua UniversityBeijing100084China State Grid New Energy Cloud Carbon Neutralization Innovation Center State Grid Zhejiang Electric Power Co.LtdHuzhou Power Supply CompanyZhejiang313000China Shanghai Marine Diesel Engine Research Institute.Shanghai 201108China

Electrochemical nitrogen transformation techniques represent a burgeoning avenue for nitrogen pollutant remediation and synthesizing valuable nitrogenous products from atmospheric *** compounds(IMCs)nanocrystals,featured with unique geometric,electronic and functional properties,have emerged as promising *** review discusses various synthesis approaches for IMCs,including thermal annealing,wet chemical synthesis,electrochemical synthesis,and other emerging methods,analyzing their advantages and *** we summarized the recent advances of IMCs in electrocatalytic nitrogen transformation reactions,such as nitrate reduction reaction,nitric oxide reduction reaction,nitrogen reduction reaction,and hydrazine oxidation *** significant progress,challenges remain in the field,particularly in adopting more refined strategies to improve catalyst performance and *** review aims to comprehensively understand the structural properties of IMCs and their structure-performance relationship,guiding the development of more efficient and stable catalysts for future nitrogen electrochemistry.

关键词： Intermetallic compounds Electrocatalysis Nitrogen transformation reactions Synthesis methods Catalyst design

CMOS Temperature Sensors: From Module Design to System Design

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Chinese Journal of Electronics 2025年第1期34卷 16-25页

作者： Zhong tang Xiao-Peng Yu Zheng shi Nianxiong Nick Tan Vango Technologies Inc. Zhejiang Univerisity

In a smart complementary metal-oxide semiconductor(CMOS) temperature sensor, the temperature information is converted to an electrical signal, such as voltage, current, or time delay, and then it is digitized by an analog-to-digital converter. Instead of categorizing sensors according to their sensing elements, this work introduces different CMOS temperature sensors based on their signal processing domains of the readout circuits. To design a suitable sensor for a specific application, two general design methodologies are also introduced with state-of-the-art examples. Depending on the applications, the corresponding types of the sensor and design methodology can be chosen to optimize the performance.

关键词： Temperature sensors Design methodology Circuits Voltage Signal processing Sensor systems Sensors Transistors System analysis and design MOS devices