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Tuberculosis Meningitis Associated with Poncet’s Disease: A Rare Case in a Young senegalese Patient

第28届中国气象学会年会

作者： shao Dong ZHANG Fan YI Chun Ming HUANG Kai Ming HUANG school of Electronic Information, Wuhan University, Wuhan, Hubei, People’s Republic of China

We proposed a broad spectral data analyzing method to study the height and seasonal variability of gravity wave associated dynamics in the lower atmosphere in middle latitudes by using the radiosonde data at Miramar nas

关键词： Radiosonde observations of lower atmosphere dynamics associated with gravity waves in middle latitudes

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Case Reports in Clinical Medicine 2023年第7期12卷 223-226页

作者： Thioub Daouda Alassane sarr Papa L. J. Diouf Aboubakar s. Badiane seck Mamadou Ndèye A. Lakhe Agbogbenkou T. D. Lawson sylvie A. Diop Moussa seydi service des Maladies Infectieuses et Tropicales CHNU Fann Dakar Sénégal UFR des sciences de la santé Université Iba Der Thiam de Thiès Thiès Sénégal

Described by Antonin Poncet in 1897, Poncet’s disease is a non-destructive (non-erosive) inflammatory arthritis secondary to a mycobacterial infection, without an identified infectious agent in the affected joints. Neuromeningeal localization of tuberculosis (TB) is rare but remains the most severe with hight mortality and permanent neurological damage. Association of Poncet’s rheumatism and TB is rare, even less a neuromeningeal localization. We report here a case of optic nerve compression syndrome complicating tuberculous meningitis associated with Poncet’s rheumatism characterized by a good outcome. This was an 18-year-old female with no reported pathological history, who was admitted for obnubilation. The symptoms started two weeks before her hospitalization and were marked by fever and headache. On admission, the examination revealed obnubilation, bilateral pyramidal deficit syndrome, right ptosis and areactive mydriasis predominating on the right, meningeal syndrome, and intense inflammatory polyarthralgia. The brain CT showed meningeal contrast enhancement with moderate dilatation of ventricles. GeneXpert MTB/rif in CsF was positive. Rheumatoid factors (latex and Waaler-Rose test) and anti-CCP antibodies were negative. Anti-nuclear, anti-native DNA and anti-nas antibodies were negative. Ophthalmological examination revealed optic nerve compression syndrome associated with extrinsic and intrinsic oculomotor paralysis in the right eye. Orbito-encephalic MRI showed compression of the optic nerve, and hydrocephalus. Under antituberculosis treatment, we noticed disappearance of arthralgia in three weeks, regression of intracranial hypertension and improvement of vision.

关键词： Tuberculosis Meningitis Poncet’s Disease

Insight of surface treatments for CMOs compatibility of Inas nanowi

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Nano Research 2019年第3期12卷 581-586页

作者： Daya s. Dhungana Anne Hemeryck Nicolo sartori Pier-Francesco Fazzini Filadelfo Cristiano sebastien R. Plissard CNRs LAAS-CNRS Universite de Toulouse F-31400 Toulouse France LPCNO INSA Universite de Toulouse Toulouse France

A CMOs compatible process is prese nted in order to grow self-catalyzed Inas nano wires on silic on by molecular beam epitaxy. The crucial step of this process is a new in-situ surface preparation under hydrogen (gas or plasma) during the substrate degassing combined with an in-situ arsenic ann eali ng prior to growth. Morphological and structural characterizati ons of the Inas nano wires are prese nted and growth mecha nisms are discussed in detail. The major in flue nee of surface termi nation is exposed both experime ntally and theoretically using statistics on ensemble of nanowires and density functional theory (DFT) calculations. The differences observed between Molecular Beam Epitaxy (MBE) and Metal Organic Vapor Phase Epitaxy (MOVPE) growth of I nas nano wires can be explai ned by these differe nt surfaces termi nations. The transition between a vapor solid (Vs) and a vapor liquid solid (VLs) growth mechanism is presented. Optimized growth conditions lead to very high aspect ratio nano wires (up to 50 nm in diameter and 3 micron in len gth) without passi ng the 410℃ thermal limit, which makes the whole process CMOs compatible. Overall, our results suggest a new method for surface preparation and a possible tuning of the growth mechanism using different surface termi nations.

关键词： Ⅲ-Ⅴ semiconductors on silicon Inas nanowires self-catalyzed growth hydrogen preparation growth modeling density functional theory (DFT) modeling

Photoisomerization of Provitamin D in Hydrogel Matrix

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soft 2013年第2期2卷 8-12页

作者： I. P. Terenetskaya Yu. M. samchenko T. N. Orlova N. A. Pasmurceva P. s. Kapinos I. E. Boldeskul Z. R. Ulberg Institute of Physics NAS Ukraine Prospekt Nauki Kyiv Ukraine Ovcharenko Institute of Biocolloid Chemistry NAS Ukraine Acad. Vernadsky Blvd. Kyiv Ukraine

study of interfacial processes between incorporated biomolecules and hydrogel matrix is of primary importance for the application of synthetic hydrogels as biomaterials, sensors, etc. Their hydrophilic nature, however, hampers fat-soluble biomolecule incorporation. We synthesized N-isopropylacrylamide (NIPAAm)- and Acrylamide (AA)-based hydrogels with hydrophilic-lipophilic balance that under specific conditions permit homogeneous incorporation of provitamins D3(7-dehydrocholesterol) and D2(ergosterol) dissolved in ethanol. similarity of provitamins D photoisomerization in such hydrogel matrices with the photoreaction in ethanol shows great potential of the novel material for personal dosimetry of biologically active ‘antirachitic’ UV radiation.

关键词： Hydrogels Provitamin D Photoisomerization UV Biodosimeter

慢性乙型肝炎患者停止核苷(酸)类似物后有限的持续反应

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临床肝胆病杂志 2020年第2期36卷 298-298页

作者：李德钊郭晓林 LIEM Ks FUNG s WONG DK 吉林大学第一医院感染病中心肝病科不详

【据《Gut》2019 年8 月报道】题:慢性乙型肝炎患者停止核苷(酸)类似物后有限的持续反应:随机对照试验的结果(多伦多停止试验)(作者Liem Ks 等)虽然大多数慢性乙型肝炎患者通过长期的核苷(酸)类似物(nas)治疗可达到有效的病毒学抑制,但... 详细信息

【据《Gut》2019 年8 月报道】题:慢性乙型肝炎患者停止核苷(酸)类似物后有限的持续反应:随机对照试验的结果(多伦多停止试验)(作者Liem Ks 等)虽然大多数慢性乙型肝炎患者通过长期的核苷(酸)类似物(nas)治疗可达到有效的病毒学抑制,但有些患者可能不需要终身治疗。

关键词：核苷(酸)类似物慢性乙型肝炎患者终身治疗随机对照试验持续反应多伦多病毒学抑制停止

聚甲基丙烯酸甲酯对二硫化钼拉伸应变控制及拉曼光谱研究

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机电工程技术 2023年第11期52卷 61-64页

作者：丘育辉陈伟权邓壬癸刘一颉何梓锋常雨李沭浩 Ivan s.Babichuk 杨建五邑大学智能制造学部江门广东529020 乌克兰国家科学院半导体物理研究所乌克兰基辅03680

自石墨烯问世以来,二维过渡金属硫化物二硫化钼(Mos_(2))成为了科研人员的关注热点。Mos_(2)在其原子厚度下具有独特的光学、电学和机械性能,是制造柔性电子器件的理想材料。在机械性能方面,Mos_(2)可以承受较大的应变,比传统的半导体... 详细信息

自石墨烯问世以来,二维过渡金属硫化物二硫化钼(Mos_(2))成为了科研人员的关注热点。Mos_(2)在其原子厚度下具有独特的光学、电学和机械性能,是制造柔性电子器件的理想材料。在机械性能方面,Mos_(2)可以承受较大的应变,比传统的半导体材料高出了许多。研究中常使用聚二甲基硅氧烷(PDMs)直接作为单层Mos_(2)的柔性衬底,但由于它们之间的范德华力十分微弱,柔性衬底在拉伸和弯曲过程中,单层Mos_(2)会发生较大的滑移,对柔性衬底施加的应变不能有效地传递到二维Mos_(2)的晶格上,导致应变传递效率低下。为提高Mos_(2)应变传递效率,提出了将聚甲基丙烯酸甲酯(PMMA)旋涂在单层Mos_(2)上对其进行封装的方法,使PM‐MA与单层Mos_(2)形成强的相互作用力。结果表明,对PMMA进行多次应变控制时,传递到Mos_(2)的应变都相同,证实了Mos_(2)在应变过程中不会发生滑移。采用化学气相沉积法(CVD)制备Mos_(2),并用聚甲基丙烯酸甲酯(PMMA)转移到柔性衬底上。通过对柔性衬底施加应变控制,研究单层Mos_(2)在PMMA上应变传递时的拉曼光谱,探究PMMA对Mos_(2)的应变控制,证实Mos_(2)应变传递的有效性。

关键词：二硫化钼化学气相沉积法拉曼光谱应变 PMMA

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Hepatocyte apoptosis fragment product cytokeratin-18 M30 level and non-alcoholic steatohepatitis risk diagnosis:an international registry study

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Chinese Medical Journal 2023年第3期136卷 341-350页

作者： Huai Zhang Rafael s.Rios Jerome Boursier Rodolphe Anty Wah-Kheong Chan Jacob George Yusuf Yilmaz Vincent Wai-sun Wong Jiangao Fan Jean-Francois Dufour George Papatheodoridis Li Chen Jorn M.schattenberg Junping shi Liang Xu Grace Lai-Hung Wong Naomi F.Lange Margarita Papatheodoridi Yuqiang Mi Yujie Zhou Christopher D.Byrne Giovanni Targher Gong Feng Minghua Zheng Department of Biostatistics and Medical Record The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang 325000China Department of Hepatology MAFLD Research CenterThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang 325000China service d’Hépato-Gastroentérologie et Oncologie Digestive Centre Hospitalier Universitaire d’AngersAngersFrance Laboratoire HIFIH UPRES EA3859SFR ICAT 4208Universitéd’AngersAngersFrance Université Cote d’Azur CHUINSERMU1065C3M06204 NiceFrance Gastroenterology and Hepatology Unit Department of MedicineFaculty of MedicineUniversity of MalayaKuala LumpurMalaysia storr Liver Centre Westmead Institute for Medical ResearchWestmead Hospital and University of SydneySydneyNSWAustralia Department of Gastroenterology School of MedicineMarmara UniversityIstanbulTurkey Department of Gastroenterology School of MedicineRecep Tayyip Erdogan UniversityRizeTurkey Department of Medicine and Therapeutics The Chinese University of Hong KongHong Kong 999077China Department of Gastroenterology Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200000China University Clinic for Visceral surgery and Medicine InselspitalUniversity Hospital BernBernSwitzerland Graduate school for Health sciences University of BernBernSwitzerland Academic Department of Gastroenterology Medical School of National and Kapodistrian University of AthensGeneral Hospitalof Athens“Laiko”AthensGreece Department of Gastroenterology Ruijin HospitalShanghai 200000China Metabolic Liver Research Program I Department of MedicineUniversity Medical Center MainzMainzGermany The Affiliated Hospital of Hangzhou Normal University HangzhouZhejiang 310000China Tianjin second People’s Hospital Tianjin 300000China Division of Gastroenterology and Hepatology Key Laboratory of Gastroenterology and HepatologyMinistry of HealthRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai Institute of Digestive DiseaseShanghai 200000Ch

Background:Liver biopsy for the diagnosis of non-alcoholic steatohepatitis(nasH)is limited by its inherent invasiveness and possible sampling *** studies have shown that cytokeratin-18(CK-18)concentrations may be useful in diagnosing nasH,but results across studies have been *** aimed to identify the utility of CK-18 M30 concentrations as an alternative to liver biopsy for non-invasive identification of ***:Individual data were collected from 14 registry centers on patients with biopsy-proven non-alcoholic fatty liver disease(NAFLD),and in all patients,circulating CK-18 M30 levels were *** with a NAFLD activity score(nas)≥5 with a score of≥1 for each of steatosis,ballooning,and lobular inflammation were diagnosed as having definite nasH;individuals with a nas≤2 and no fibrosis were diagnosed as having non-alcoholic fatty liver(NAFL).Results:A total of 2571 participants were screened,and 1008(153 with NAFL and 855 with nasH)were finally *** CK-18 M30 levels were higher in patients with nasH than in those with NAFL(mean difference 177 U/L;standardized mean difference[sMD]:0.87[0.69–1.04]).There was an interaction between CK-18 M30 levels and serum alanine aminotransferase,body mass index(BMI),and hypertension(Pspectively).CK-18 M30 levels were positively associated with histological nas in most *** area under the receiver operating characteristics(AUROC)for nasH was 0.750(95%confidence intervals:0.714–0.787),and CK-18 M30 at Youden’s index maximum was 275.7 U/*** sensitivity(55%[52%–59%])and positive predictive value(59%)were not ***:This large multicenter registry study shows that CK-18 M30 measurement in isolation is of limited value for non-invasively diagnosing nasH.

关键词： Apoptosis Diagnosis Cytokeratin-18 Liver histology Non-alcoholic steatohepatitis Non-alcoholic fatty liver disease

与地壳活动有关的ULF地磁变化:RIKEN-nasDA项目概要和最新结果

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世界地震译丛 2005年第3期36卷 50-53页

作者： K．Hattori I．Takahashi M．Hayakawa N．Isezaki K．Yumoto T．Nagao s．Uyeda 李琪杨冬梅不详中国地震局地球物理研究所

尽管地震短临预报极其重要,并且经过了人们多年的努力,但它仍是目前未能解决的问题。近年来,与地震相关的电磁现象被认为是解决地震短临预报的有效途径之一。现在已经积累了大量的地震电磁前兆信号的震例,这些信号分布在很宽的频带范围(... 详细信息

尽管地震短临预报极其重要,并且经过了人们多年的努力,但它仍是目前未能解决的问题。近年来,与地震相关的电磁现象被认为是解决地震短临预报的有效途径之一。现在已经积累了大量的地震电磁前兆信号的震例,这些信号分布在很宽的频带范围(DC-VHF)内,其中ULF地磁变化是最有希望的地磁前兆之一。通过监测ULF地磁变化,有望实现地震短临预报。本文将阐述从ULF电磁信号中提取震磁异常变化的方法。

关键词：地磁变化 ULF 地壳活动地震短临预报概要项目电磁现象前兆信号信号分布地磁前兆异常变化电磁信号震例震磁

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应用阿片制剂妇女的妊娠结局

世界核心医学期刊文摘（妇产科学分册） 2006年第12期2卷 17-17页

作者： Fajemirokun-Odudeyi O. sinha C. Tutty s. s.W. Lindow 张新艳 Women and Children's Hospital Hull Royal InfirmaryAnlaby RoadHullHU3 2JZUnited Kingdom

Background:Opiate use in pregnancy is on the increase. There are a number of complications associated with this problem but current data from UK centres are sparse. Design:A retrospective study. setting:A North of England Hospital. Methods:Maternal and neonatal case records were studied and a standard data set completed. Main outcome measures:Maternal and neonatal outcomes were classified by the woman’s drug usage at the end of pregnancy. Results:One hundred and ten babies born to 108 women were studied and 41%had evidence of previous exposure to the hepatitis C virus. Women who took heroin in later pregnancy were significantly more likely than women who were stabilised on methadone to have a baby who needed morphine (40%versus 19%),had higher mean maximum neonatal abstinence scores (nas) (5.8 versus 4.7) and stayed in the neonatal unit significantly longer (mean 17.2 days versus 11.8 days). There were two neonatal deaths and the overall rate of prematurity was 29%. Conclusions:The outcome for pregnancy in women who use opiates is complicated by high rates of prematurity and neonatal death. Women who used heroin in later pregnancy had babies who developed more severe nas and needed a longer hospital stay than women who used only methadone.

关键词：妊娠结局阿片制剂妊娠晚期早产率妇女分娩暴露史药品用法丙肝病毒住院天数英国北部