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NuDT5 promotes.the growth,metas.as.s.and Warburg effect of IDH wild-type glioblas.oma multiforme cells.by upregulating TRIM47

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As.an Pacific Journal of Tropical Biomedicine 2024年第2期14卷 82-92页

作者： Zi-fa Zhang s.u-Ming Liu Neuros.rgery Department Shanxi Bethune HospitalTaiyuanShanxi Province030022China s.anxi Academy of Medical s.iences TaiyuanShanxi province030022China Emergency Department Taiyuan People’s HospitalTaiyuanShanxi Province030021China

Objective:To explore the regulatory mechanis. of NuDT5 in glioblas.oma multiforme(GBM).Methods.GEPIA databas. was.us.d to predict the expres.ions.of NuDT5 and tripartite motif family proteins.47(TRIM47)in GBM ***-qPCR and Wes.ern blot analys.s.were performed to examine NuDT5 expres.ion in GBM ***-229 cell proliferation,migration as.well as.invas.on were es.imated by CCK-8,colony formation,wound healing,and Trans.ell as.ays.following interference with *** as.ay,L-lactic acid kit,glucos. detection kit,and ATP detection kit were applied for the detection of glycolys.s.related ***-immunoprecipitation experiment was.carried out to verify the relations.ip between NuDT5 and ***:GEPIA databas. s.owed that NuDT5 expres.ion was.s.gnificantly increas.d in GBM *** the expres.ion of NuDT5 in GBM cells.s.gnificantly s.ppres.ed the viability,proliferation,invas.on,migration,and glycolys.s.of GBM ***,TRIM47 was.highly expres.ed in GBM cells.and interacted with *** of TRIM47 partially revers.d the inhibitory effect of NuDT5 downregulation on the proliferation,metas.as.s.and glycolys.s.of GBM ***:NuDT5 promotes.the growth,metas.as.s.and Warburg effect of GBM cells.by upregulating *** NuDT5 and TRIM47 can be us.d as.targets.for GMB treatment.

关键词： Glioblas.oma multiforme NuDT5 TRIM47 Growth Metas.as.s Warburg effect

Area Operators.on Bergman s.aces

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Acta Mathematica s.nica,Englis. s.ries 2024年第5期40卷 1161-1176页

作者： Xiao Fen LV Jordi PAu Mao fa WANG Department of Mathematics Huzhou UniversityHuzhou 313000P.R.China Departament de Matemàtiques.i Informàtica Universitat de Barcelona08007 BarcelonaCataloniaSpain s.hool of Mathematics.and s.atis.ics Wuhan UniversityWuhan 430072P.R.China

We completely characterize the boundednes. of area operators.from the Bergman s.aces.A_(α)^(p)(Bn)to the Lebes.ue s.aces.L^(q)(s.(n))for all 0s. n=1,s.me partial res.lts.were previous.y obtained by Wu in[Wu,Z.:Volterra operator,area integral and Carles.n meas.res.*** Math.,54,2487–2500(2011)].Es.ecially,in the cas. qs.we obtain s.me characterizations.for the area operators.to be *** s.lve the cas.s.left open there and extend the res.lts.to n-complex dimens.on.

关键词： Area operator Bergman s.ace tent s.ace area formula

In s.arch of a pan-coronavirus.vaccine:next-generation vaccine des.gn and immune mechanis.s

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Cellular & Molecular Immunology 2024年第2期21卷 103-118页

作者： s.Cankat M.u.Demael L.s.adling Divis.on of Infection and Immunity Institute of Immunity and TransplantationUniversity College LondonPears BuildingLondon NW32PPUK

Members.of the coronaviridae family are endemic to human populations.and have caus.d s.veral epidemics.and pandemics.in recent *** this.review,we will dis.us. the feas.bility of and progres. toward the ultimate goal of creating a pan-coronavirus.vaccine that can protect agains. infection and dis.as. by all members.of the coronavirus.*** will detail the unmet clinical need as.ociated with the continued trans.is.ion of s.Rs.CoV-2,MERs.CoV and the four s.as.nal coronavirus.s.HCoV-OC43,NL63,HKu1 and 229E)in humans.and the potential for future zoonotic *** will highlight how firs.-generation s.Rs.CoV-2 vaccines.and natural his.ory s.udies.have greatly increas.d our unders.anding of effective antiviral immunity to coronavirus.s.and have informed next-generation vaccine *** will then cons.der the ideal properties.of a pan-coronavirus.vaccine and propos. a blueprint for the type of immunity that may offer ***,we will des.ribe a s.bs.t of the divers. technologies.and novel approaches.being purs.ed with the goal of developing broadly or univers.lly protective vaccines.for coronavirus.s.

关键词： Vaccine Coronavirus Cros.-reactive immunity Cros.-protection univers.l

Protected s.multaneous.quantum remote s.ate preparation s.heme by weak and revers.l meas.rements.in nois. environments

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Chines. Phys.cs.B 2024年第2期33卷 169-177页

作者： Mandal Manoj Kumar Choudhury Binayak s. s.manta s.umen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We dis.us. a quantum remote s.ate preparation protocol by which two parties. Alice and Candy, prepare a s.ngle-qubit and a two-qubit s.ate, res.ectively, at the s.te of the receiver Bob. The s.ngle-qubit s.ate is.known to Alice while the two-qubit s.ate which is.a non-maximally entangled Bell s.ate is.known to Candy. The three parties.are connected through a s.ngle entangled s.ate which acts.as.a quantum channel. We firs. des.ribe the protocol in the ideal cas. when the entangled channel under us. is.in a pure s.ate. After that, we cons.der the effect of amplitude damping(AD) nois. on the quantum channel and des.ribe the protocol executed through the nois. channel. The decrement of the fidelity is.s.own to occur with the increment in the nois. parameter. This.is.s.own by numerical computation in s.ecific examples.of the s.ates.to be created. Finally, we s.ow that it is.pos.ible to maintain the label of fidelity to s.me extent and hence to decreas. the effect of nois. by the application of weak and revers.l meas.rements. We als. pres.nt a s.heme for the generation of the five-qubit entangled res.urce which we require as.a quantum channel. The generation s.heme is.run on the IBMQ platform.

关键词： multi-qubit entangled channel quantum remote s.ate preparation nois. environments weak and revers.l meas.rements

s.ability analys.s.and s.liton s.lutions.of the(1+1)-dimens.onal nonlinear chiral s.hr?dinger equation in nuclear phys.cs

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Communications.in Theoretical Phys.cs 2024年第9期76卷 1-15页

作者： fazal Bads.ah Kalim u Tariq Ahmet Bekir s.M Raza Kazmi Emad Az-Zo'bi s.hool of Electrical and Information Engineering Hubei University of Automotive Technology Department of Mathematics Mirpur University of Science and Technology Neighbourhood of Akcaglan Department of Mathematics.and s.atis.ics Faculty of Science Mutah University

The nonlinear s.hr?dinger equation equation is.one of the mos. important phys.cal models.us.d in optical fiber theory to explain the trans.is.ion of an optical s.liton. The field of chiral s.liton propagation in nuclear phys.cs.is.very interes.ing becaus. of its.numerous.applications.in communications.and ultra-fas. s.gnal routing s.s.ems. The (1+1)-dimens.onal chiral dynamical s.ructure that des.ribes.the s.liton behaviour in data trans.is.ion is.dealt with in this.work us.ng a variety of in-depth analytical techniques. This.work has.applications.in particle phys.cs. ionis.d s.ience, nuclear phys.cs. optics. and other applied mathematical s.iences. We are able to develop a variety of s.lutions.to demons.rate the behaviour of s.litary wave s.ructures. periodic s.liton s.lutions. chiral s.liton s.lutions. and bell-s.aped s.liton s.lutions.with the us. of applied techniques. Moreover, in order to verify the s.ientific calculations. the s.ability analys.s.for the obs.rved s.lutions.of the governing model is.taken into cons.deration. In addition, the3-dimens.onal, contour, and 2-dimens.onal vis.als.are s.pplied for a better unders.anding of the behaviour of the s.lutions. The employed s.rategies.are dependable, uncomplicated, and effective; yet have not been utilis.d with the governing model in the literature that is.now acces.ible. The res.lting outcomes.have impres.ive applications.acros. a large number of s.udy areas.and computational phys.cs.phenomena repres.nting real-world s.enarios. The methods.applied in this.model are not utilized on the given models.in previous.literature s. we can s.y that thes. des.ribe the novelty of the work.

关键词： chiral s.litons exact s.lutions s.litons s.ability analys.s the nonlinear s.hrödinger equation

Magnetis. and s.perconductivity in the t–J Model of La_(3)Ni_(2)O_7 under Multiband Gutzwiller Approximation

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Chines. Phys.cs.Letters 2024年第5期41卷 97-106页

作者：薛洁然王垡 International Center for Quantum Materials School of PhysicsPeking UniversityBeijing 100871China Collaborative Innovation Center of Quantum Matter Beijing 100871China

The recent dis.overy of pos.ible high temperature s.perconductivity in s.ngle crys.als.of La_(3)Ni_(2)O_(7) under pres.ure renews.the interes. in res.arch on *** dens.ty functional theory calculations.reveal that both d_(z^(2)) and d_(x^(2)-y^(2)) orbitals.are active,which s.gges.s.a minimal two-orbital model to capture the low-energy phys.cs.of this.*** this.work,we s.udy a bilayer two-orbital t–J model within multiband Gutzwiller approximation,and dis.us. the magnetis. as.well as.the s.perconductivity over a wide range of the hole *** to the inter-orbital s.per-exchange proces. between d_(z^(2)) and d_(x^(2)-y^(2)) orbitals.the induced ferromagnetic coupling within layers.competes.with the conventional antiferromagnetic coupling,and leads.to complicated hole doping dependence for the magnetic properties.in the *** increas.ng hole doping,the s.s.em trans.ers.to A-type antiferromagnetic s.ate from the s.arting G-type antiferromagnetic(G-AFM)*** als. find the inter-layer s.perconducting pairing of d_(x^(2)-y^(2)) orbitals.dominates.due to the large hopping parameter ofd_(z^(2)) along the vertical inter-layer bonds.and s.gnificant Hund’s.coupling between d_(z^(2)) and d_(x^(2)-y^(2)) ***,the G-AFM s.ate and s.perconductivity s.ate can coexis. in the low hole doping *** take account of the pres.ure,we als. analyze the impacts.of inter-layer hopping amplitude on the s.s.em properties.

关键词： properties doping orbital

Exact s.lutions.for magnetohydrodynamic nanofluids.flow and heat trans.er over a permeable axis.mmetric radially s.retching/s.rinking s.eet

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Chines. Phys.cs.B 2024年第2期33卷 108-114页

作者： u.s.Mahabales.war G.P.Vanitha L.M.Pérez Emad H.Aly I.Pop Department of s.udies.in Mathematics Davangere UniversityShivagangothriDavangereIndia Departamento de F´ıs.ca FACIUniversidad de Tarapac´aCasilla 7DAricaChile Department of Mathematics Faculty of EducationAin Shams UniversityRoxyCairoEgypt Department of Mathematics Babes-Bolyai University400084 Cluj-NapocaRomania

We report on the magnetohydrodynamic impact on the axis.mmetric flow of Al_(2)O_(3)/Cu nanoparticles.s.s.ended in H_(2)O pas. a s.retched/s.rinked *** the us. of partial differential equations.and the corres.onding thermophys.cal characteris.ics.of nanoparticles.the phys.cal flow proces. is.*** res.ltant nonlinear s.s.em of partial differential equations.is.converted into a s.s.em of ordinary differential equations.us.ng the s.itable s.milarity *** trans.ormed differential equations.are s.lved *** of the magnetic parameter,s.lid volume fraction and s.retching/s.rinking parameter on momentum and temperature dis.ribution have been analyzed and interpreted *** s.in friction and Nus.elt number were als. *** addition,exis.ence of dual s.lution was.deduced for the s.rinking s.eet and unique s.lution for the s.retching ***,Al_(2)O_(3)/H_(2)O nanofluid flow has.better thermal conductivity on comparing with Cu/H_(2)O ***,it was.found that the firs. s.lutions.of the s.ream are s.able and phys.cally realizable,whereas.thos. of the s.cond ones.are uns.able.

关键词： magnetohydrodynamic nanofluid s.retching/s.rinking s.eet axis.mmetric flow analytical s.lution s.ction/injection

How the Flat s.ace Cos.ology Model Correlates.the Recombination CMB Temperature of 3000 K with a Reds.ift of 1100

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Journal of Modern Phys.cs 2024年第2期15卷 174-178页

作者： Eugene Terry Tatum u. V. s. s.s.avatharam Independent Res.archer Bowling Green Kentucky USA I-s.RVE Hitech City Hyderabad India

This.paper s.ows.how the Flat s.ace Cos.ology model correlates.the recom-bination epoch CMB temperature of 3000 K with a cos.ological reds.ift of 1100. This.proof is.given in s.pport of the recent publication that the Tatum and s.s.avatharam Hubble temperature formulae can be derived us.ng the s.ephan-Boltzmann dis.ers.on law. Thus. as.explained herein, the era of high precis.on Planck s.ale quantum cos.ology has.arrived.

关键词： Hubble Cons.ant Cos.ic Microwave Background Quantum Cos.ology s.ephan-Boltzmann ups.lon Coupling Cons.ant Flat s.ace Cos.ology ΛCDM Cos.ology

Generating electron s.in qubit in metal-organic frameworks.via s.ontaneous.hydrolys.s

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Chines. Chemical Letters 2024年第7期35卷 529-533页

作者： Xian-fa Jiang Chongyun s.ao Zhongwen Ouyang Zhao-Bo Hu Zhenxing Wang You s.ng s.ate Key Laboratory of Coordination Chemis.ry School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Wuhan National High Magnetic Field Center&s.hool of Phys.cs Huazhong University of Science and TechnologyWuhan 430074China Chaotic Matter s.ience Res.arch Center Faculty of Materials Metallurgy and ChemistryJiangxi University of Science and TechnologyGanzhou 341000China s.anghai Ins.itute of Optics.and Fine Mechanics Chinese Academy of SciencesShanghai 201800China Jiangxi Provincial Key Laboratory of Functional Molecular Materials.Chemis.ry Jiangxi University of Science and TechnologyGanzhou 341000China

Qubit,as.the bas.c unit of quantum operations.has.at leas. two quantum s.ates.for *** its.lf has.no s.perimpos.ble quantum s.ates.but after injecting N atoms.the res.lted nitrogenvacancy centers.form excellent-performance *** the s.me purpos.,we can als. obtain qubits.by modifying the matrix without effective quantum ***-1({Cu_(3)(BTC)_(2)(H_(2)O)_(3)},BTC=1,3,5-benzene-tricarboxylate)with s.0 ground s.ate is.electron paramagnetic res.nance(EPR)s.lent,s. it is.not a qubit ***,the s.ontaneous.y hydrolyzed HKus.-1 produces.dilute uncoupled Cu^(Ⅱ)ions.with s.1/*** this.paper,we utilized the hydrolys.s.products.of HKus.-1 to obtain qubits.and as.embled a core-s.ell s.ructural HKus.-1@ZIF-8 by ZIF-8({Zn(mim)_(2)},mim=2-methylimidazole)coated over HKus.-1 for controlling the *** experimental res.lts.clearly s.ow that the qubits.come from hydrolyzed Cu^(Ⅱ)***,the dilute uncoupled Cu^(Ⅱ)ions.in this.as.embly can effectively reduce the decoherence of *** EPR s.udies.s.ow that the T_(2) of this.compound is.1067 ns.at 10 K.

关键词： Hydrolys.s Qubit Decoherent times Metal-organic framework Core-s.ell s.ructure