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Measurement of the neutron-induced total cross sections of ^(nat)Pb from 0.3 eV to 20 MeV on the Back-n at CSNS

Nuclear Science and Techniques 2024年第2期35卷 85-93页

作者： Jie-ming xue Song feng Yong-Hao chen Han Yi min Xiao Pin-Jing cheng Xin-Xiang Li Rong Liu Yi-Wei yang Zi-Jie Han Da-Jun Zhao Hao-Qiang Wang Bao-Qian Li Ji-Rong Zhao Lei-Xun Tang Wen Luo Bo Zheng School of Nuclear Science and Technology University of South ChinaHengyang 421001China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China

The neutron-induced total cross sections of natural lead have been measured in a wide energy range(0.3 eV-20 MeV)on the back-streaming white neutron beamline(Back-n)at the China Spallation Neutron *** energy was determined by the neutron total cross-section spectrometer using the time-of-flight technique.A fast multi-cell fission chamber was used as the neutron detector,and a 10-mm-thick high-purity natural lead sample was employed for the neutron transmission *** on-beam background was determined using Co,In,Ag,and Cd *** excitation function of ^(nat)Pb(n,tot)reaction below 20 MeV was calculated using the TALYS-1.96 nuclear-reaction modeling *** present results were compared with previous results,the evaluated data available in the five major evaluated nuclear data libraries(i.e.,ENDF/B-VIII.0,JEFF-3.3,JENDL-5,CENDL-3.2,and BROND-3.1),and the theoretical calculation *** agreement was found between the new results and those of previous experiments and with the theoretical curves in the corresponding *** measurement obtained the neutron total cross section of natural lead with good accuracy over a wide energy range and added experimental data in the resonance energy *** provides more reliable experimental data for nuclear engineering design and nuclear data evaluation of lead.

关键词： Neutron-induced total cross section Natural lead Time-of-flight TALYS-1.96 CSNS Back-n white neutron beamline

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Influence of Familiarity on Energy Intake and Plasma Gut Hormone Concentration in Lean and Overweight Young Male Students

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Biomedical and Environmental Sciences 2018年第10期31卷 740-748页

作者： QI Lei QI Yan Bo ZHAO Peng CHAO Hong cheng yu xue Hai feng HAN yun feng JIN Bai ming WAN Si yuan QIAN xue Yan LI Hong Jie WU Huan LI Gang LOU feng Ge School of Publie Health Qiqihar Medical University Qiqihar 161006 Heilongjiang China

Objective This study is to examine the influence of familiarity on energy intake, eating behavior, and concentration of the plasma gut hormones in lean and overweight young male subjects. Methods Twenty-eight lean and twenty-eight overweight participants were recruited. Their food consumption was documented and analyzed when they had a test meal while they were paired with friends or strangers at the same weight stature. Their eating behavior was recorded with cameras hidden in the carton, and postprandial plasma gut hormone concentration were measured. Results Compared with overweight strangers（OS）, overweight friends（OF） had increased food consumption, prolonged and decreased number of chews per 10 g food. Compared with OS, postprandial plasma concentration of cholecystokinin-8 was significantly lower in OF group at 30, 60, and 90 min, whereas the concentration of glucagon-like peptide 1 was significantly lower at 60 and 90 min. Plasma ghrelin concentration was significantly higher in the OF group than that in the OS group at 90 and 120 min. No significant differences in gut hormone concentration were observed between lean strangers（LS） and lean friends（LF） groups at all time points. Conclusion Familiarity plays an important role in increasing energy intake and in changing of postprandial gut hormone concentration in overweight individuals.

关键词： Familiarity Overweight Energy intake Gut hormone

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裂谷地层的气候和构造控制:Zscape模型分析与在松辽盆地北安断陷的应用

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吉林大学学报（地球科学版） 2006年第1期36卷 54-59页

作者：姜雪程日辉于民凤吉林大学地球科学学院长春130061

气候和构造是裂谷盆地地层形成的两个重要控制因素。Zscape数字陆地景观演化模型通过对裂谷盆地汇水扇体系的模拟揭示出一些与裂谷盆地地层形成相关的气候及构造过程。Zscape模型的相关实验结果与层序地层结构的分析认为:(1)扇面积与断... 详细信息

气候和构造是裂谷盆地地层形成的两个重要控制因素。Zscape数字陆地景观演化模型通过对裂谷盆地汇水扇体系的模拟揭示出一些与裂谷盆地地层形成相关的气候及构造过程。Zscape模型的相关实验结果与层序地层结构的分析认为:(1)扇面积与断层滑动速率成反比;(2)高水位期大量沉积物进积是断层滑动速率减小所引发的;(3)层序界面的形成与低水位和水进沉积是降水速率变化所致。这些认识用于分析北安断陷沙河子期大量扇体沉积的发育和层序结构的形成。沙河子组下部层序发育时期构造活动剧烈,上部层序发育时期构造活动相对趋于稳定,断裂活动和降水速率的变化控制了层序发育。Zscape模型及其实验结果的地质分析,以及在北安断陷的应用显示,构造和气候的单因素分析对一些地质认识,特别是沉积作用对于断裂活动的滞后性的理论解释起到了推动作用。

关键词：裂谷盆地汇水-扇体系断层滑动速率降水速率松辽盆地

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Biomarkers and potential pathogenesis of colorectal cancer-related ischemic stroke

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World Journal of Gastroenterology 2018年第43期24卷 4950-4958页

作者： Qi-Xiong Qin xue-min cheng Li-Zhi Lu yun-Fei Wei Da-cheng Wang Hai-Hua Li Guo-Hui Li Hong-Bin Liang Sheng-yu Li Li chen Zhi-Jian Liang Department of Neurology The First Affiliated Hospital of Guangxi Medical University Department of Neurology The Second Affiliated Hospital of Guangxi Medical University Department of Neurology The Ninth Affiliated Hospital of Guangxi Medical University Department of Neurology Fusui County People’s Hospital Department of Neurology Wuzhou Red Cross Hospital Department of Neurology Cenxi People’s Hospital Department of Neurology Wuming County People’s Hospital

AIM To investigate the specific biomarkers and potential pathogenesis of colorectal cancer-related ischemic stroke(CRCIS).METHODS A retrospective study was conducted on CRCIS patients(colorectal cancer patients with ischemic stroke without conventional stroke risk factors) registered at seven centers between January 2007 and December 2017. Clinical data and laboratory and imaging findings were compared with age-and sex-matched patients with colorectal cancer(CRC) without ischemic stroke that were admitted to the same hospital during the same period. Univariate and multivariate analyses were performed to analyze the independent risk factors for CRCIS. A receiver operator characteristic curve was configured to calculate the optimal cut-off value of the products of the independent risk factors for CRCIS. RESULTS A total of 114 CRCIS patients and 114 CRC patients were included. Multiple lesions in multiple vascular territories were common in CRCIS patients(71, 62.28%). The levels of plasma D-dimer, carcinoembryonic antigen(CEA), cancer antigen 125, and neutrophil count were significantly higher in CRCIS patients than in CRC patients. Multiple logistic regression analysis revealed that plasma D-dimer levels [odds ratio(OR) = 1.002, 95% confidence interval(CI): 1.001-1.003, P risk factors for CRCIS. In addition, receiver operator characteristic curve revealed that the area under curve for the products of plasma D-dimer, CEA, and neutrophil count was 0.889 ± 0.022(95%CI: 0.847-0.932, P < 0.001), and the optimal cut-off value for the product was 252.06, which was called the CRCIS Index, with a sensitivity of 86.0% and specificity of 79.8%.CONCLUSION Hypercoagulability induced by elevated CEA and neutrophils may be an important cause of CRCIS. The CRCIS index, which serves as a biomarker of CRCIS, needs further study.

关键词： Colorectal cancer Ischemic stroke Biomarker Pathogenesis

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Adhesive cryogel particles for bridging confined and irregular tissue defects

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Military Medical Research 2023年第6期10卷 763-777页

作者： Yao-Ting xue ming-yu chen Jia-Sheng Cao Lei Wang Jia-Hao Hu Si-yang Li Ji-Liang Shen Xin-Ge Li Kai-Hang Zhang Shu-Qiang Hao Sarun Juengpanich Si-Bo cheng Tuck-Whye Wong Xu-Xu yang Tie-feng Li Xiu-Jun Cai Wei yang Department of Engineering Mechanics Zhejiang UniversityHang‑zhou 310027China Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province Zhejiang UniversityHangzhou 310027China Center for X‑Mechanics Department of Engineering MechanicsZhejiang Univer‑sityHangzhou 310027China Department of General Surgery Sir Run-Run Shaw HospitalZhejiang UniversityHangzhou 310016China Soft Intelligent Materials Co. LtdSuzhou 215123China School of Biomedical Engineering and Health Sciences and Advanced Membrane Technology Research Centre Universiti Teknologi Malaysia81310 SkudaiMalaysia

Background Reconstruction of damaged tissues requires both surface hemostasis and tissue *** with damage resulting from physical trauma or surgical treatments may have arbitrary surface topographies,making tissue bridging *** This study proposes a tissue adhesive in the form of adhesive cryogel particles(ACPs) made from chitosan,acrylic acid,1-ethyl-3-(3-dimethylaminopropyl) carbodiimide(EDC) and N-hydroxysuccinimide(NHS).The adhesion performance was examined by the 180-degree peel test to a collection of tissues including porcine heart,intestine,liver,muscle,and *** of ACPs was evaluated by cell proliferation of human normal liver cells(LO2)and human intestinal epithelial cells(Caco-2).The degree of inflammation and biodegradability were examined in dorsal subcutaneous rat *** ability of ACPs to bridge irregular tissue defects was assessed using porcine heart,liver,and kidney as the ex vivo ***,a model of repairing liver rupture in rats and an intestinal anastomosis in rabbits were established to verify the effectiveness,biocompatibility,and applicability in clinical *** ACPs are applicable to confined and irregular tissue defects,such as deep herringbone grooves in the parenchyma organs and annular sections in the cavernous *** formed tough adhesion between tissues[(670.9±50.1) J/m^(2) for the heart,(607.6±30.0) J/m^(2) for the intestine,(473.7±37.0) J/m^(2) for the liver,(186.1±13.3) J/m^(2) for the muscle,and(579.3±32.3) J/m^(2) for the stomach].ACPs showed considerable cytocompatibility in vitro study,with a high level of cell viability for 3 d[(98.8±1.2)%for LO2 and(98.3±1.6)%for Caco-2].It has comparable inflammation repair in a ruptured rat liver(P=0.58 compared with suture closure),the same with intestinal anastomosis in rabbits(P=0.40 compared with suture anastomosis).Additionally,ACP-based intestinal anastomosis(less than 30 s) was remarkably faster than the convention

关键词： Tissue reconstruction Wet adhesion Adhesive hydrogel Bioadhesive

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Insight into Superior Visible Light Photocatalytic Activity for Degradation of Dye over Corner-truncated Cubic Ag2O Decorated TiO2 Hollow Nanofibers

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Chinese Journal of Structural Chemistry 2020年第3期39卷 588-597,380页

作者： chen Yi-Lan XU yu-Xian LIN Dai-feng LUO Yong-Jin xue Hun chen Qing-Hua Fujian Key Laboratory of Pollution Control&Resource Reuse College of Environment Science and EngineeringFujian Normal UniversityFuzhou 350007China School of Ecological Environment and Urban Construction Fujian University of TechnologyFuzhou 350118China Fujian Polytechnic Normal University Fuqing 350300China

Ag2O/TiO2 heterostructure has been constructed by loading corner-truncated cubic Ag2O on the TiO2 hollow nanofibers via an electrospinning-precipitation method. Compared to individual Ag2O and TiO2, Ag2O/TiO2 heterostructure exhibits obviously enhanced photocatalytic activity for the photodegradation of methyl orange(MO) under visible light irradiation. The composite with molar ratio of Ag2O to TiO2 at 4:10 exhibits the best photocatalytic performance with MO degraded 93% in 6 min. The superior activity is mainly attributed to the surface plasmon resonance(SPR) effect of metallic Ag in-situ produced during the photocatalytic process, which can favor electron transfer to the conduction band of TiO2. This leads to the efficient separation of photogenerated carriers, thus a superior photodegradation activity. Moreover, the energy band alignments of Ag2O/TiO2 heterostructure are calculated, which provides strong support for the proposed mechanism.

关键词： visible light photocatalysis corner-truncated cubic Ag2O TiO2 hollow nanofibers surface plasmon resonance heterostructure

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A chromosome-level genome assembly of rugged rose (Rosa rugosa) provides insights into its evolution, ecology, and floral characteristics

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Horticulture Research 2021年第1期8卷 1939-1951页

作者： Fei chen Liyao Su Shuaiya Hu Jia-yu xue Hui Liu Guanhua Liu Yifan Jiang Jianke Du yushan Qiao Yannan Fan Huan Liu Qi yang Wenjie Lu Zhu-Qing Shao Jian Zhang Liangsheng Zhang feng chen Zong-ming(Max)cheng College of Horticulture Nanjing Agricultural UniversityNanjing 210095China Academy for Advanced Interdisciplinary Studies Nanjing Agricultural UniversityNanjing 210095China BGI-Shenzhen Beishan Industrial ZoneYantian DistrictShenzhen 518083China Department of Biology University of CopenhagenCopenhagenDenmark Grandomics Biosciences Co. LtdWuhanChina School of Life Sciences Nanjing UniversityNanjingChina College of life science Nantong UniversityNantongChina Genomics and Genetic Engineering Laboratory of Ornamental Plants College of Agriculture and BiotechnologyZhejiang UniversityHangzhouChina Department of plant sciences University of TennesseeKnoxvilleTNUSA

Rosa rugosa,commonly known as rugged rose,is a perennial ornamental *** produces beautiful flowers with a mild fragrance and colorful seed *** many other cultivated roses,*** adapts to a wide range of habitat types and harsh environmental conditions such as salinity,alkaline,shade,drought,high humidity,and frigid ***,we produced and analyzed a high-quality genome sequence for *** to understand its ecology,floral characteristics and *** HiFi reads were initially used to construct the draft genome of ***,and then Hi-C sequencing was applied to assemble the contigs into 7 *** obtained a 382.6Mb genome encoding 39,704 protein-coding *** genome of *** appears to be conserved with no additional whole-genome duplication after the gamma whole-genome triplication(WGT),which occurred~100 million years ago in the ancestor of core *** on a comparative analysis of the high-quality genome assembly of *** and other high-quality Rosaceae genomes,we found a unique large inverted segment in the Chinese rose *** and a retroposition in strawberry caused by post-WGT *** also found that floral development-and stress response signaling-related gene modules were retained after the *** MADS-box genes involved in floral development and the stress-related transcription factors DREB2A-INTERACTING PROTEIN 2(DriP2)and PEPTIDE TRANSPORTER 3(PTR3)were found to be positively selected in evolution,which may have contributed to the unique ability of this plant to adapt to harsh *** summary,the high-quality genome sequence of *** provides a map for genetic studies and molecular breeding of this plant and enables comparative genomic studies of Rosa in the near future.

关键词： breeding characteristics evolution

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Wearable skin-like optoelectronic systems with suppression of motion artifacts for cuff-less continuous blood pressure monitor

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National Science Review 2020年第5期7卷 849-862页

作者： Haicheng Li Yinji Ma Ziwei Liang Zhouheng Wang yu Cao yuan Xu Hua Zhou Bingwei Lu Ying chen Zhiyuan Han Shisheng Cai xue feng Key Laboratory of Applied Mechanics Department of Engineering Mechanics Tsinghua University Center for Flexible Electronics Technology Tsinghua University Intensive Care Unit Beijing Tsinghua Changgung Hospital Institute of Flexible Electronics Technology of Tsinghua University

According to the statistics of the World Health Organization, an estimated 17.9 million people die from cardiovascular diseases each year, representing 31%of all global deaths. Continuous non-invasive arterial pressure (CNAP) is essential for the management of cardiovascular diseases. However, it is difficult to achieve long-term CNAP monitoring with the daily use of current devices due to irritation of the skin as well as the lack of motion artifacts suppression. Here, we report a high-performance skin-like optoelectronic system integrated with ultra-thin flexible circuits to monitor CNAP. We introduce a theoretical model via the virtual work principle for predicting the precise blood pressure and suppressing motion artifacts, and propose optical difference in the frequency domain for stable optical measurements in terms of skin-like devices. We compare the results with the blood pressure acquired by invasive (intra-arterial) blood pressure monitoring for>1500 min in total on 44 subjects in an intensive care unit. The maximum absolute errors of diastolic and systolic blood pressure were±7/±10 mm Hg, respectively, in immobilized, and±10/±14 mm Hg, respectively, in walking scenarios. These strategies provide advanced blood pressure monitoring techniques, which would directly address an unmet clinical need or daily use for a highly vulnerable population.

关键词： skin-like devices optoelectronics blood pressure monitor optical measurement

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Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults

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Journal of Geriatric Cardiology 2020年第2期17卷 85-95页

作者： Qiong LIU Fang-Chao LIU Ke-Yong HUANG Jian-Xin LI xue-Li yang Xin-Yan WANG Ji-Chun chen Xiao-Qing LIU Jie CAO Chong SHEN Ling yu Fang-Hong LU Xian-Ping WU Lian-cheng ZHAO Ying LI Dong-Sheng HU Xiang-feng LU Jian-feng HUANG Dong-feng GU Key Laboratory of Cardiovascular Epidemiology Chinese Academy of Medical SciencesBeijingChina Department of Epidemiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Division of Epidemiology Guangdong Provincial People’s Hospital and Cardiovascular InstituteGuangzhouChina Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjingChina Department of Cardiology Fujian Provincial HospitalFuzhouChina Cardio-Cerebrovascular Control and Research Center Institute of Basic MedicineShandong Academy of Medical SciencesJinanChina Sichuan Center for Disease Control and Prevention ChengduChina Department of Prevention Medicine Shenzhen University School of MedicineShenzhenChina

Background In China,lack of evidence remains a significant challenge for the national initiative to promote physical activity(PA).We aimed to quantify the beneficial effects of meeting or maintaining the recommended PA level[150 minutes per week(min/wk)of moderate PA or 75 min/wk of vigorous PA or an equivalent combination]on incident cardiovascular disease(CVD)among Chinese *** We included 100,560 participants without history of CVD from three cohorts in the Prediction for Atherosclerotic Cardiovascular Disease risk in China(China-PAR)*** proportional hazards models were used to estimate hazard ratios(HRs)and 95%confidence intervals(CIs)for CVD events and its subtypes,including stroke,coronary heart disease,heart failure,and CVD *** During a median follow-up of 7.3 years(range:6–15 years),777,163 person-years and 4693 incident CVD events were *** with participants who were inactive at baseline,the multivariable adjusted HR(95%CI)of developing CVD was 0.74(0.69–0.79)for those who met recommended moderate to vigorous physical activity(MVPA)level at ***,the risk of CVD incidence was reduced with increment of MVPA(Ptrendriod of follow-up had a substantial lower risk of incident CVD with the HR(95%CI)of 0.57(0.43–0.77).Conclusions The findings demonstrated that meeting and maintaining the recommended MVPA level could reduce the cardiovascular *** adoption of the PA recommendations would have considerable health impacts to the Chinese population.

关键词： Cardiovascular disease China Cohort study Physical activity

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Silencing miRNA-324-3p protects against cerebral ischemic injury via regulation of the GATA2/A1R axis

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Neural Regeneration Research 2022年第11期17卷 2504-2511页

作者： An-Qi Zhang Lu Wang Yi-Xiu Wang Shan-Shan Hong yu-Shan Zhong Ru-Yi yu Xin-Lu Wu Bing-Bing Zhou Qi-min yu Hai-feng Fu Shuang-Dong chen yun-Chang Mo Qin-xue Dai Jun-Lu Wang Department of Anesthesiology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Anesthesiology Wenzhou Central HospitalWenzhouZhejiang ProvinceChina

Previous studies have suggested that miR-324-3p is related to the pathophysiology of cerebral ischemia,but the mechanism underlying this relationship is unclea *** this study,we found that miR-324-3p expression was decreased in patients with acute ischemic stroke and in in vitro and in vivo models of ischemic stro ***-324-3p agomir potentiated ischemic brain damage in rats subjected to middle cerebral artery occlusion,as indicated by increased infarct volumes and cell apoptosis rates and greater neurological *** a PC12 cell oxygen-glucose deprivation/reoxygenation model,a miR-324-3 p mimic decreased cell viability and expression of the anti-apoptotic protein BCL2 and increased expression of the pro-apoptotic protein BAX and rates of cell apoptosis,whereas treatment with a miR-324-3p inhibitor had the opposite *** miR-324-3p increased adenosine A1 receptor(A1R)expression thro ugh regulation of GATA binding protein 2(GATA2).These findings suggest that silencing miR-324-3p reduces ischemic brain damage via the GATA2/A1R axis.

关键词： acute ischemic stroke adenosine A1 receptor apoptosis cerebral ischemia-reperfusion injury cortical neurons GATA2 middle cerebral artery occlusion miR-324-3p oxygen-glucose deprivation/reoxygenation PC12 cells

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