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中国科技教育 2011年第7期 34-38页

作者： renee Clacy james Wandersee 姜景（翻译）密西西比州立大学路易斯安那州立大学中国科协青少年科技中心

关于沙子的科学沙子多种多样，“每一类沙子都可以讲述_段有关当地独特地理和地质构造的风化、搬运和沉积的故事。二氧化硅因其硬度和稳定性成为最常见的沙子成分j。尤其是石英质的沙土。除此之外，沙土姐含有其他成分，如小粒的岩石或... 详细信息

关于沙子的科学沙子多种多样，“每一类沙子都可以讲述_段有关当地独特地理和地质构造的风化、搬运和沉积的故事。二氧化硅因其硬度和稳定性成为最常见的沙子成分j。尤其是石英质的沙土。除此之外，沙土姐含有其他成分，如小粒的岩石或矿物质、生物体残骸，甚至还有小颗粒的人造物质!

关键词：科学世界调查花费地质构造二氧化硅矿物质沙子稳定性

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Mesenchymal stem cell-based therapy for ischemic stroke

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Chinese Neurosurgical journal 2016年第4期2卷 233-238页

作者： johnathon D.Anderson Missy T.Pham Zelenia Contreras Madeline Hoon Kyle D.Fink Henrik j.johansson julien Rossignol Department of Internal Medicine Stem Cell Program University of California Davis Davis USAInstitute for Regenerative Cures University of California Davis Medical Center 2921 Stockton Blvd Room 1300 Sacramento CA 95817 USA Department of Internal Medicine Stem Cell Program University of California Davis Davis USA Department of Oncology-Pathology Karolinska InstituteCancer Proteomics Davis USA College of Medicine Central Michigan University Mt PleasantUSA

Ischemic stroke represents a major,worldwide health burden with increasing *** affected by ischemic strokes currently have few clinically approved treatment options *** currently approved treatments for ischemic stroke have narrow therapeutic windows,severely limiting the number of patients able to be *** stem cells represent a promising novel treatment for ischemic *** studies have demonstrated that mesenchymal stem cells functionally improve outcomes in rodent models of ischemic *** studies have also shown that exosomes secreted by mesenchymal stem cells mediate much of this *** the present review,we summarize the current literature on the use of mesenchymal stem cells to treat ischemic *** studies investigating the mechanisms underlying mesenchymal stem cells tissue healing effects are warranted and would be of benefit to the field.

关键词： Mesenchymal stem cells Exosomes Ischemic stroke

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Low-protein diet accelerates wound healing in mice post-acute injury

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Burns & Trauma 2021年第1期9卷 339-350页

作者： jonathan j.Hew Roxanne j.Parungao Craig P.Mooney julian K.Smyth Sarah Kim Kevin H.-Y.Tsai Huaikai Shi Cassandra Chong renee C.F.Chan Beba Attia Caroline Nicholls Zhe Li Samantha M.Solon-Biet David G.Le Couteur Stephen j.Simpson Marc G.jeschke Peter K.Maitz Yiwei Wang Burns Research and Reconstructive Surgery ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Bone Biology Group ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Adrenal Steroids Laboratory ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Electron Microscopy Unit Anatomical PathologyConcord HospitalSydneyAustralia 2139 Burns Unit Concord Repatriation General HospitalConcordAustralia 2139 Ageing and Alzheimer Institute and ANZAC Research Institute Concord HospitalUniversity of SydneySydneyAustralia 2139 Charles Perkins Centre and School of Life and Environmental Sciences University of SydneyAustralia 2006 Sunnybrook Research Institute TorontoOntarioCanadaM4N 3M5 School of Pharmacy Nanjing University of Chinese MedicineNanjingPR China 210023

Background:Wound healing processes are influenced by macronutrient intake(protein,carbohydrate and fat).The most favourable diet for cutaneous wound healing is not known,although highprotein diets are currently favoured *** experimental study investigates the optimal macronutrient balance for cutaneous wound healing using a mouse model and the Geometric Framework,a nutrient modelling method,capable of analyzing the individual and interactive effects of a wide spectrum of macronutrient ***:Two adjacent and identical full-thickness skin excisions(1 cm^(2))were surgically created on the dorsal area of male C57BL/6 *** were then allocated to one of 12 high-energy diets that varied in protein,carbohydrate and fat *** select diets,wound healing processes,cytokine expression,energy expenditure,body composition,muscle and fat reserves were ***:Using the Geometric Framework,we show that a low-protein intake,coupled with a balanced intake of carbohydrate and fat is optimal for wound *** fed a low-protein diet progressed quickly through wound healing stages with favourable wound inflammatory cytokine expression and significantly accelerated collagen *** local processes were associated with an increased early systemic inflammatory response and a higher overall energy expenditure,related to metabolic changes occurring in key macronutrient reserves in lean body mass and fat ***:The results suggest that a low-protein diet may have a greater potential to accelerate wound healing than the current clinically used high-protein diets.

关键词： Wound healing Macronutrients Cutaneous Geometric Framework Mouse model Low-protein diet Nutrition

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建立卒中医疗体系的建议美国卒中协会特别工作组关于建立卒中体系的建议

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国际脑血管病杂志 2005年第12期13卷 883-894页

作者： Lee H. Schwamm Arthur Pancioli joe E. Acker Ⅲ Larry B. Goldstein Richard D. Zorowitz Timothy j. Shephard Peter Moyer Mark Gorman S. Claiborne johnston Pamela W. Duncan Phil Gorelick jeffery Frank Steven K. Stranne renee smith William Federspiel Katie B. Horton Ellen Magnis Robert j. Adams 林豪杰董继宏金丽蓉彭伟锋汪昕复旦大学附属中山医院神经内科

在美国,卒中一直是残疾和死亡的重要原因.每年约有70万例美国人新发或复发卒中,在与其他心血管病分开评价时,卒中在美国仍是第三位死亡原因.在美国卒中还是严重和长期残疾的第一位原因[1].

关键词：初级卒中中心二级预防患者医务人员医务工作者急性卒中防治体系医疗体系美国卒中协会医疗亚急性期工作组

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细胞内可控过氧化氢的产生和荧光成像

细胞内可控过氧化氢的产生和荧光成像

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中国光学学会2011年学术大会

作者：郭亨长 Hossein Aleyasin Scott Howard Bryan C Dickinson renee Haskew-Layton Demirhan Kobat Vivian S Lin David Rivera Christopher j Chang Rajiv R Ratan 许春辉 Burke Medical Research Institute Weill Medical College of Cornell University785 Mamaroneck AvenueWhite Plains School of Applied Physics & Engineering Cornell UniversityIthaca Department of Chemistry University of CaliforniaBerkeley Howard Hughes Medical Institute University of CaliforniaBerkeley School of Applied Physics & Engineering Cornell University

过氧化氢(H2O2)在过去一直被认为是以氧气为代谢的生物产生的有害物质,H2O2导致的氧化应激与衰老、肿瘤、糖尿病等多种疾病的病理有关1-4。近几年的研究发现,H2O2作为细胞内第二信使对生理学和病理学的研究都起着重要作用1,2。适量的H2O... 详细信息

过氧化氢(H2O2)在过去一直被认为是以氧气为代谢的生物产生的有害物质,H2O2导致的氧化应激与衰老、肿瘤、糖尿病等多种疾病的病理有关1-4。近几年的研究发现,H2O2作为细胞内第二信使对生理学和病理学的研究都起着重要作用1,2。适量的H2O2能激发细胞信号传导,从而有助于细胞生长和增殖、伤口修复、神经保护和血管功能的调节等。

关键词：活性氧过氧化氢氧化应激双光子荧光成像

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较大直肠腺瘤中经肛门内镜显微手术与内镜下黏膜切除术的随机对照试验(TREND研究)

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英国医学杂志中文版 2018年第11期21卷 676-676页

作者： renee M Barendse Gijsbert D Musters Eelco j R de Graaf Frank j C van den Broek Esther C j Consten Pascal G Doornebosch james C Hardwick Ignace H j T de Hingh Chrisiaan Hoft jeroen M jansen A W Marc van Milligen de Wit George P van der Schelling Erik j Schoon Matthijs P Schwartz Bas L A M Weusten Marcel G Dijkgraaf Paul Fockens Willem A Bemelman Evelien Dekker TREND研究小组李佳宁(译) 吴东(校) 不详北京协和医院消化科

摘要目的非随机研究表明内镜下黏膜切除术(endoscopic mucosal resection,EMR)在切除直肠较大腺瘤时与经肛门内镜显微手术(transanal endoscopic microsurgery,TEM)同样有效,但EMR可能更具成本效益且相对安全。本试验旨在对比摘除较... 详细信息

摘要目的非随机研究表明内镜下黏膜切除术(endoscopic mucosal resection,EMR)在切除直肠较大腺瘤时与经肛门内镜显微手术(transanal endoscopic microsurgery,TEM)同样有效,但EMR可能更具成本效益且相对安全。本试验旨在对比摘除较大直肠腺瘤时EMR与TEM的临床结局与成本效益。

关键词：随机对照试验显微手术切除术内镜黏膜肛门肠腺成本效益

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