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作者： rajan Kumar singh 东北大学

学位级别：硕士

本论文的目的是分析盐业贸易有限公司的库存管理与净销售额,净利润和采购的关系。Salt Trading Corporation Limited(STC)成立四十多年,通过尼泊尔政府和私营部门的共同努力,确保在全国各地适当供应和分配基本消费品。这项研究的主要目... 详细信息

本论文的目的是分析盐业贸易有限公司的库存管理与净销售额,净利润和采购的关系。Salt Trading Corporation Limited(STC)成立四十多年,通过尼泊尔政府和私营部门的共同努力,确保在全国各地适当供应和分配基本消费品。这项研究的主要目标是衡量STC库存管理实践的表现与库存管理问题相关联,并分析他们的解决方式,有助于STC的盈利能力。分析库存水平的位置及其在STC中的趋势,并分析库存与净销售额,净利润,购买和利息支出的关系。为了实现这些目标,收集了初级和次级数据。采用均值、标准差、变异系数、相关系数、回归概率误差、趋势分析等统计手段分析数据。同样,也使用了财务工具,如比率,库存周转率和库存保持日。在分析了目前盐品贸易公司库存管理的实践后,得出的主要结论是,库存与总资产、净销售额和当前比率在过去四年有所增加,但在过去两年有所下降。最初,库存与净利润比率较小,此后,除了 2014/2015财年的净利润如此之高,但去年的比率严重下降之外,比率呈持续上升的趋势。在整个研究期间,存货周转率呈下降趋势。2013/2014和2014/2015五个会计年度的库存持有天数的平均值非常高。除了 2012/2013财政年度和2015/2016财政年度之外,净销售额和库存趋势在相同的模式中波动,而库存库存差异的共同效率低于净销售额差异的共同效率。净利润趋势保持波动,净利润差异的协同效率高于库存差异的协同效率。利息费用的趋势是在可变利率连续增加,有库存的高波动。库存差异的共同效益高于利息支出差异的共同效益。在2015/2016财政年度,采购量略有减少,而库存急剧增加,再次下降。库存差异的共同效率低于采购差异的共同效率。净销售额超过购买,因此在期间结束时,净销售额和购买的趋势相同。净销售额差异的协同效率略低于采购差异的协同效率。从回归结果中可以发现,库存与净销售额、净利润、除利息支出外的采购存在负相关关系。在净销售额和库存之间找到最高的相关性(r=0.83),而最低的相关性是净利润和库存(r=0.2)。回归结果,发现库存与净销售额、净利润、购买除利息支出之间存在负相关关系。这项研究提出了更好的库存管理的以下几点。这项研究使用简单的回归分析,但是,它可以使用多元回归分析,以确定库存水平的回归模型。在研究期间,净销售额、净利润和采购额出现波动时,库存量在增加。因此,没有适当的库存协调与净销售,净利润和采购交易。管理层强烈建议有效地应用库存管理系统。没有适当的库存水平与净销售和采购的协调。因此,库存的平均持有期高,为了保持最佳的库存水平,应更好地协调库存与净销售,采购等。我们可以通过告诉盐贸易公司(STC)库存管理的表现并不令人满意,必须投入艰苦的工作才能在不久的将来在这个全球开放市场中生

关键词：分析净销售额净利润采购成本分析库存管理比率分析等

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Effect of dual and new generation wide-base tire assembly on inverted pavements

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Journal of Road Engineering 2022年第2期2卷 124-136页

作者： rajan singh Baghel Sridhar Reddy Kasu Anush K.Chandrappa School of Infrastructure Indian Institute of Technology BhubaneswarOdisha 752050India Department of Civil Engineering Sreyas Institute of Engineering and TechnologyHyderabad 500068India

The conventional flexible pavements have been constructed such that the stiffness of the layer reduces with *** crust thickness becomes significantly high for heavy traffic corridors resulting in the consumption of large quantities of construction materials and also increasing environmental *** pavements with the aggregate interlayer(AIL)or stress absorbing membrane interlayer(SAMI)are considered to be one of the alternatives for thick conventional flexible pavements for heavy traffic *** AIL or SAMI is placed between a stiff cement-treated base and asphalt concrete layer to function as crack relief *** change in the composition alters the behaviour of inverted pavements compared to the conventional flexible *** the other hand,wide-base tires are being increasingly preferred by trucking industries due to increased fuel economy and cargo ***,the effect of wide-base tires on the performance of inverted pavements is yet to be *** this study,the 3D finite element(FE)models of inverted pavements considering different crack relief layers were developed,and load from dual-wheel and wide-base tires were *** stress-strain evolution in the various layers of inverted pavements was investigated and discussed in this *** results indicated the higher stress and strains due to wide base tires compared to the dual-wheel ***,pavement with SAMI was found to result in lower stress and strains in the asphalt concrete layer compared to AIL pavements.

关键词： Aggregate interlayer Inverted pavement Shear strain Stress absorbing membrane interlayer Wide-base tire

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Pathophysiological mechanisms underlying gastrointestinal symptoms in patients with COVID-19

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World Journal of Gastroenterology 2021年第19期27卷 2341-2352页

作者： Byungchang Jin rajan singh Se Eun Ha Hannah Zogg Paul J Park Seungil Ro Department of Physiology and Cell Biology University of Nevada School of MedicineRenoNV 89557United States Department of Medicine Renown HealthRenoNV 89557United States

Gastrointestinal(GI)symptoms,such as diarrhea,abdominal pain,vomiting,and anorexia,are frequently observed in patients with coronavirus disease 2019(COVID-19).However,the pathophysiological mechanisms connecting these GI symptoms to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infections remain *** studies indicate that the entry of SARS-CoV-2 into intestinal cells leads to downregulation of angiotensin converting enzyme 2(ACE2)receptors resulting in impaired barrier *** intestinal ACE2 functions as a chaperone for the amino acid transporter B0AT1,the B0AT1/ACE2 complex within the intestinal epithelium acts as a regulator of gut microbiota composition and *** to the B0AT1/ACE2 complex lead to microbial dysbiosis through increased local and systemic immune *** studies have also suggested that altered serotonin metabolism may be the underlying cause of GI disorders involving *** findings of elevated plasma serotonin levels and high fecal calprotectin in COVID-19 patients with diarrhea indicate that the viral infection evokes a systemic inflammatory response that specifically involves the ***,the elevated proinflammatory cytokines correlate with elevated serotonin and fecal calprotectin levels further supporting the evidence of GI inflammation,a hallmark of functional GI ***,the finding that rectal swabs of COVID-19 patients remain positive for SARS-CoV-2 even after the nasopharynx clears the virus,suggests that viral replication and shedding from the GI tract may be more robust than that of the respiratory tract,further indicating fecal-oral transmission as another important route of viral *** review summarized the evidence for pathophysiological mechanisms(impaired barrier function,gut inflammation,altered serotonin metabolism and gut microbiota dysbiosis)underlying the GI symptoms in patients with COVID-19.

关键词： COVID-19 Gastrointestinal symptoms Gut microbiota dysbiosis Impaired barrier function Serotonin Angiotensin converting enzyme 2 receptor

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Cancer Susceptibility for Male Breast Cancer Assessed by SNP-A Analysis and Risk Alleles of TP53, MDM2, VEGF, VEGFR1, HIF1Aand BRCA1

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Advances in Breast Cancer Research 2021年第4期10卷 218-233页

作者： Sarika Sharma Vasudha Sambyal Kamlesh Guleria Ruhi Kapahi Neeti rajan singh Mridu Manjari Human Cytogenetics Laboratory Guru Nanak Dev University Amritsar India Department of Surgery Sri Guru Ram Das Institute of Medical Sciences and Research Amritsar India Department of Pathology Sri Guru Ram Das Institute of Medical Sciences and Research Amritsar India

Male Breast Cancer (MBC) has a familial component thus identification of polymorphic risk alleles of candidate genes and/or cytogenetic anomalies may help to predict the risk for the offspring of MBC patients. The conventional metaphase cytogenetics can indicate loci that are hotspots while analysis by single nucleotide polymorphism arrays (SNP-A) can identify chromosomal defects which may play a role in the etiology of cancer. A cumulative genotype risk due to each allele of candidate genes of the signaling pathways regulating c-MYC, HIF1A, TP53 and BRCA1 may be a factor facilitating cancer development. Cancer risk was assessed in a 35-year-old healthy son of a 60-year-old MBC patient with a family history of cancer by metaphase cytogenetics, SNP-A and analysis of 25 polymorphisms in six genes TP53, MDM2, VEGF,

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Trend in Observed and Projected Maximum and Minimum Temperature over N-W Himalayan Basin

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Journal of Mountain Science 2015年第2期12卷 417-433页

作者： Dharmaveer singh Sanjay K JAIN rajan Dev GUPTA GIS Cell Motilal Nehru National Institute of Technology Allahabad Water Resources Systems Division National Institute of Hydrology Department of Civil Engineering Motilal Nehru National Institute of Technology Allahabad

Recently, study in past trends of climate variables gained significant consideration because of its contribution in adaptions and mitigation strategies for potential future changes in climate, primarily in the area of water resource management. Future interannual and inter-seasonal variations in maximum and minimum temperature may bring significant changes in hydrological systems and affect regional water resources. The present study has been performed to observe past(1970-2010) as well as future(2011-2100)spatial and temporal variability in temperature(maximum and minimum) over selected stations of Sutlej basin located in North-Western Himalayan region in India. The generation of future time series of temperature data at different stations is done using statistical downscaling technique. The nonparametric test methods, modified Mann-Kendall test and Cumulative Sum chart are used for detecting monotonic trend and sequential shift in time series of maximum and minimum temperature. Sen's slope estimator test is used to detect the magnitude of change over a period of time on annual and seasonal basis. The cooling experienced in annual TMax and TMin at Kasol in past(1970-2010) would be replaced by warming in future as increasing trends are detected in TMax during 2020 s and 2050 s and in TMin during 2020 s, 2050 s and 2080 s under A1 B and A2 scenarios. Similar results of warming are also predicted at Sunnifor annual TMin in future under both scenarios which witnessed cooling during 1970-2010. The rise in TMin at Rampur is predicted to be continued in future as increasing trends are obtained under both the scenarios. Seasonal trend analysis reveals large variability in trends of TMax and TMin over these stations for the future periods.

关键词： Statistical downscaling model Canadian Coupled Global Climate Model Temperature MannKendall test Sen’s slope estimator

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