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Typical Frobenius Coverings

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Acta Mathematica Sinica,English Series 2010年第11期26卷 2209-2214页

作者： Yan WANG rong quan FENG Jaeun LEE Department of Mathematics Yah Tai University Yah Tai 264005 P. R. China LMAM School of Mathematical Sciences Peking University Beijing 100871 P. R. China Department of Mathematics Yeungnam University Kyongsan 712-749 Korea

A covering p from a Cayley graph Cay（G, X） onto another Cay（H, Y） is called typical Frobenius if G is a Frobenius group with H as a Frobenius complement and the map p ： G →H is a group epimorphism. In this paper, we emphasize on the typical Frobenius coverings of Cay（H, Y）. We show that any typical Frobenius covering Cay（G, X） of Cay（H, Y） can be derived from an epimorphism /from G to H which is determined by an automorphism f of H. If Cay（G, X1） and Cay（G, X2） are two isomorphic typical Frobenius coverings under a graph isomorphism Ф, some properties satisfied by Фare given.

关键词： Frobenius group typical Frobenius covering isomorphic

Leveraging machine learning techniques for predicting pancreatic neuroendocrine tumor grades using biochemical and tumor markers

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World Journal of Clinical Cases 2019年第13期7卷 1611-1622页

作者： Rui-quan Zhou Hong-Chen Ji Qu Liu, Chun-yu Zhu rong Liu School of Medicine Nankai University Tianjin 300071 China The Second Department of Hepatobiliary Surgery Chinese PLA General Hospital Beijing 100853 China

BACKGROUND The incidence of pancreatic neuroendocrine tumors (PNETs) is now increasing rapidly. The tumor grade of PNETs significantly affects the treatment strategy and prognosis. However, there is still no effective way to non-invasively classify PNET grades. Machine learning (ML) algorithms have shown potential in improving the prediction accuracy using comprehensive data. AIM To provide a ML approach to predict PNET tumor grade using clinical data. METHODS The clinical data of histologically confirmed PNET cases between 2012 and 2018 were collected. A method of minimum P for the Chi-square test was used to divide the continuous variables into binary variables. The continuous variables were transformed into binary variables according to the cutoff value, while the P value was minimum. Four classical supervised ML models, including logistic regression, support vector machine (SVM), linear discriminant analysis (LDA) and multi-layer perceptron (MLP) were trained by clinical data, and the models were labeled with the pathological tumor grade of each PNET patient. The performance of each model, including the weight of the different parameters, were evaluated. RESULTS In total, 91 PNET cases were included in this study, in which 32 were G1, 48 were G2 and 11 were G3. The results showed that there were significant differences among the clinical parameters of patients with different grades. Patients with higher grades tended to have higher values of total bilirubin, alpha fetoprotein, carcinoembryonic antigen, carbohydrate antigen 19-9 and carbohydrate antigen 72-4. Among the models we used, LDA performed best in predicting the PNET tumor grade. Meanwhile, MLP had the highest recall rate for G3 cases. All of the models stabilized when the sample size was over 70 percent of the total, except for SVM. Different parameters varied in affecting the outcomes of the models. Overall, alanine transaminase, total bilirubin, carcinoembryonic antigen, carbohydrate antigen 19-9 and

关键词： Machine learning Pancreatic neuroendocrine tumors Tumor grade Biochemical indexes Tumor markers

Impaired XPO5 function leads to transportation failure of microRNA precursor

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Science China(Life Sciences) 2017年第6期60卷 677-679页

作者： yu-quan Wei State Key Laboratory of Biotherapy and Cancer Center West China Hospital Sichuan Universityand Collaborative Innovation Center for BiotherapyChengdu 610041China

MicroRNAs（miRNAs）constitute a class of small non-coding RNAs that participate in various biological processes by repressing protein translation or destabilizing target *** biogenesis begins with the transcription of primary miRNAs（pri-miRNAs）in the cell nucleus,which are then cleaved by the Drosha/DGCR complex into precursor miRNAs（pre-miRNAs）.The pre-miRNAs are transported by exportin-5（XPO5）from the nucleus to the cytoplasm,

关键词： miRNAs nucleus microRNA processed mature Dicer constitute cytoplasm impaired transportation

Preparation of Hydrophilic UHMWPE Hollow Fiber Membranes by Chemically Bounding Silica Nanoparticles

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Chinese Journal of Polymer Science 2021年第2期39卷 189-200,I0006页

作者： Lian-Lian Fan Jia-You quan Hao Zhang Jun-rong yu Zu-Ming Hu Yan Wang Shanghai Collaborative Innovation Center for High Performance Fiber Composites College of Materials Science and EngineeringDonghua UniversityShanghai 201620China Sinochem International Corporation Shanghai 200126China

In this work, ultra-high molecular weight polyethylene (UHMWPE) microfiltration hollow fiber membranes prepared via the thermally induced phase separation (TIPS) method were modified by chemically bounding hydrophilic silica (SiO2) nanoparticles onto the surface to improve anti-fouling performance. A range of testing techniques including attenuated total reflection Flourier transformed infrared spectroscopy(ATR-FTIR), X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscopy (FE-SEM), water contact angle, mechanical test,filtration and anti-fouling performance were carried out to discuss the influence of different modification conditions on the properties of the membranes. The prepared hollow fiber membranes display the significantly excellent performance when the vinyl trimethoxy silane (VTMS) concentration was 13%, the pH value of the hydrolyzate was 4 and the hydrolysis reaction time was 6 h. In particular, the hydrophilicity of modified membranes was improved effectively, resulting in the enhancement of membrane anti-fouling properties. The results of this work can be consulted for improving the anti-fouling performance of the UHMWPE microfiltration hollow fiber membrane applied in the field of water purification.

关键词： Hollow fiber membrane Hydrophilic Anti-fouling Silica(SiO2)nanoparticles Water purification

Stepwise assembly to construct stable copper(I) cluster-based circularly polarized luminescent MOFs

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Science China Chemistry 2025年

作者： Jing-Wen Xie Meng-Ting Wang Yan Jin Si Li Jian-Hua Qin Shuang-quan Zang Tomas C.W.Mak College of Chemistry Henan Key Laboratory of Crystalline Molecular Functional Materials Zhengzhou University College of Chemistry and Chemical Engineering Luoyang Normal University Department of Chemistry The Chinese University of Hong Kong

Circularly polarized luminescence （CPL） materials have been extensively studied in recent years owing to their widespread applications in 3D display,optical storage,optical anti-counterfeiting,and biological imaging,***（I） clusters have emerged as a promising candidate for CPL materials,driven by their cost-effectiveness,superior luminescent properties,precise structure,and low ***,the poor environmental stability of copper（I） clusters renders their synthesis and preservation challenging,thereby significantly impeding their ***,we have designed and synthesised a chiral double-coordinated ligand in order to construct copper（I） cluster nodes that can be further *** anticipated,by utilizing stepwise assembly strategy,a Cu4cluster node co-modified by chiral alkynyl ligands and triphenylphosphine was further assembled with Cd2+ions to obtain 2D layers structure,L/*** L/D-Cu4-Cd exhibits excellent stability and optical properties,including bright yellow emission,solvent-responsive luminescence,and CPL activity with a maximum glumup to 2.0×10-3,which shows potential applications in the WLED and *** interestingly,the material also exhibits deflection ability towards different wavelengths of linearly polarized light,showing certain potential in the preparation of circular polarizer.

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NUMERICAL RESEARCHES ON INTERACTION BETWEEN PROPELLERS IN UNIFORM FLOW

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Journal of Hydrodynamics 2012年第5期24卷 675-683页

作者： FENG Xue-mei LU Chuan-jing WUQiong CAI rong-quan School of Naval Architecture Ocean and Civil Engineering Shanghai Jiao Tong University Shanghai 200240China Marine Design and Research Institute of China Shanghai 200011 China

Numerical simulations of the flow around two bidirectional staggered propellers are conducted in uniform flow. The computed open water performance of the fore-propeller is compared with the corresponding experimental results, and the influence of the fore-propeller on the aft one is carefully investigated. It is found that the inflow around the aft propeller close to the side of the fore is especially affected by the fore one, leading to abnormal circumferential distribution of force on the blade in the shade region. For either forces or velocity distributions, the abnormal changes behave contrarily for cases with the rotating speed larger or smaller than the idle. Moreover, the more the rotating speed of the fore differs from the idle, the larger the abnormal values become.

关键词： numerical simulation interaction propellers open water performance

Hypothalamic paraventricular nucleus stimulation reduces intestinal injury in rats with ulcerative colitis

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World Journal of Gastroenterology 2016年第14期22卷 3769-3776页

作者： quan-Jun Deng Ding-Jing Deng Jin Che Hai-rong Zhao Jun-Jie yu Yong-yu Lu Department of Neurosurgery General Hospital Affiliated to Tianjin Medical University Department of Gastroenterology General Hospital Affiliated to Tianjin Medical University Department of Cerebral surgery people's Hospital of Haimen

AIM: To investigate the effect and mechanism of stimulation of the hypothalamic paraventricular nucleus with glutamate acid in rats with ulcerative colitis(UC).METHODS: The rats were anesthetized with 10% chloral hydrate via abdominal injection and treated with an equal volume of TNBS + 50% ethanol enema, injected into the upper section of the anus with the tail facing up. Colonic damage scores were calculated after injecting a certain dose of glutamic acid into the paraventricular nucleus(p VN), and the effect of the nucleus tractus solitarius(NTS) and vagus nerve in alleviating UC injury through chemical stimulation of the p VN was observed in rats. Expression changes of C-myc, Apaf-1, caspase-3, interleukin(IL)-6, and IL-17 during the protection against UC injury through chemical stimulation of the p VN in rats were detected by Western blot. Malondialdehyde(MDA) content and superoxide dismutase(SOD) activity in colon tissues of rats were measured by colorimetric methods. RESULTS: Chemical stimulation of the PVN significantly reduced UC in rats in a dose-dependent manner. The protective effects of the chemical stimulationof the p VN on rats with UC were eliminated after chemical damage to the p VN. After glutamate receptor antagonist kynurenic acid was injected into the p VN, the protective effects of the chemical stimulation of the p VN were eliminated in rats with UC. After AVpVl receptor antagonist([Deamino-penl, val4, D-Arg8]-vasopressin) was injected into NTS or bilateral chemical damage to NTS, the protective effect of the chemical stimulation of p VN on UC was also eliminated. After chemical stimulation of the p VN, SOD activity increased, MDA content decreased, C-myc protein expression significantly increased, caspase-3 and Apaf-1 protein expression significantly decreased, and IL-6 and IL-17 expression decreased in colon tissues in rats with UC. CONCLUSION: Chemical stimulation of the hypothalamic p VN provides a protective effect against UC injury in rat

关键词： Paraventricular nucleus Nucleus tractus solitarius Ulcerative colitis Arginine vasopressin 2 4 6-trinitrobenzene sulfonic acid

Constructions of 11/2-designs from Symplectic Geometry over Finite Fields

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Acta Mathematica Sinica,English Series 2015年第9期31卷 1367-1378页

作者： Zhao CHAI rong quan FENG Li Wei ZENG LMAM School of Mathematical Sciences Peking University

In this paper, we construct some 1 1/2-designs, which are also known as partial geometric designs, using totally isotropic subspaces of the symplectic space and generalized symplectic graphs. Furthermore, these 1^-des... 详细信息

关键词： 1 1/2-design totally isotropic subspace generalized symplectic graph directed strongly reg-ular graph

Correlation analysis between microbial diversity and physicochemical indices of Koumiss

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Food Bioscience 2022年第5期49卷 1342-1352页

作者： Yang Yang You Na Wu Erdenebat Oyunsuren yu rong Wang Zhuang Guo quan Shuang College of Food Science and Engineering Inner Mongolia Agricultural UniversityHohhotInner Mongolia Autonomous Region010018China College of Food Science and Technology Hubei University of Arts and SciencesXiangyang CityHubei Province441000China

This study examined the influence of change in microbial flora during fermentation on the quality of *** microbial diversity of Koumiss samples was analyzed at different fermentation periods using high-throughput ***,the physiochemical(protein,fat,ash,moisture,lactose,soluble solids,and energy)and functional(antioxidant activity,cholesterol removal ability,and bacteriostatic ability)indices were ***,a correlation analysis was made between the change in microbial flora structure and physicochemical and functional *** dominant bacteria phylum was Firmicutes,and the dominant bacteria genus was *** the early stage of fermentation,the dominant bacteria phylum of fresh mare milk was Actinobacteria,while the dominant bacteria genus was *** fungal community structure,the dominant phylum was Ascomycota,and the dominant genus was *** the early stage of fermentation too,the dominant fungal phylum was Ascomycota,but the dominant genus was *** lactose and energy contents of fresh mare milk were higher,which was consistent with other physiochemical *** fermentation,the contents of lactose,soluble solids,and energy decreased,and the contents of protein and fat *** functional characteristics of fermented mare milk are ***,it has a strong antibacterial *** bacteria that positively correlated with lactose,soluble solids,and energy were Rothia,Streptococcus,Enhydrobacter,and Macrococcus(p<0.05).Also,DPPH hydroxyl free radical capacity and reducing power positively correlated with Pichia(p<0.05);Hydroxyl radical scavenging ability positively correlated with Yarrowia and Dipodascus(p<0.05);Energy and lactose negatively correlated with Yarrowia and Dipodascus(p<0.05).

关键词： Koumiss Microbial diversity Nutritional quality characteristics Functional characteristics Correlation