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Air entrainment in a vertical dropshaft with limited air supply

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Theoretical & Applied Mechanics Letters 2018年第5期8卷 315-319,362页

作者： qiang ding Yiyi Ma David Z.Zhu Department of Civil Engineering Zhejiang University Department of Civil and Environmental Engineering University of Alberta

Dropshafts are vertical structures widely used in urban drainage systems and buildings for water *** this paper,a physical model study was conducted to investigate the air entrainment in the dropshaft under various flow regimes with and without air *** from the experiments,the air entrainment mechanisms varied with the water flow regimes in the *** there was no water plug formed in the dropshaft,air could be supplied directly from *** the water plug was formed,while without venting,the air was replenished only from downstream intermittently and then in the form of large air bubble traveling upwards to the airspace at the top;while with venting,air was mainly replenished from the dropshaft top and no large air bubble was *** experimental results also showed that the amount of entrained air in the dropshaft with venting was greater than that without venting.

关键词： Air entrainment Air supply Bubble Flow regime Dropshaft

Novel Flexibilizer for Cement Rotary Kiln Bricks

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China's Refractories 2021年第2期30卷 7-11页

作者： qiang ding Martin GEITH Hilmar SCHULZE-BERGKAMEN RHI Magnesita Dalian 116600China RHI Magnesita Leoben 8700Austria

A new type of magnesia spinel brick containing a novel flexibilizer was *** publication presents an investigation on its chemical composition,physical properties and cement clinker *** to conventional magnesia spinel bricks,the new brick type shows reduced amounts of alumina,significantly improved hot properties and resistance against cement clinker attack whilst keeping its textural flexibility on the same *** trials revealed satisfactory results and confirmed the novel flexibilizer concept.

关键词： magnesia spinel brick flexibilizer cement clinker resistance

区域电网的分省备用容量留取方案(一):机制设计

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中国电机工程学报 2023年第3期43卷 61-69页

作者：蔡帜戴赛崔晖丁强李宇轩李强电力调度自动化技术研究与系统评价北京市重点实验室(中国电力科学研究院有限公司) 北京市海淀区100192

在传统调度模式下,区域电网的分省备用容量一般按照计划模式留取,对省间备用互济的可调用性缺乏考虑,随着新能源和电力市场的快速发展,已难以适应未来电网的发展要求。为此,该文首先分析国内外备用留取方法现状;然后,基于现行标准和各... 详细信息

在传统调度模式下,区域电网的分省备用容量一般按照计划模式留取,对省间备用互济的可调用性缺乏考虑,随着新能源和电力市场的快速发展,已难以适应未来电网的发展要求。为此,该文首先分析国内外备用留取方法现状;然后,基于现行标准和各区域管理规定对备用的分类和机制进行探讨,分析高比例新能源接入和现货市场建设对备用容量的影响,探讨分省备用管理特点和各区域负备用留取方案;在此基础上,基于我国的调度模式,设计了区域电网备用容量预留机制,确定电力市场中的备用品种、特点和相互关系,从高比例新能源接入对电网充裕性、安全性、灵活性的影响出发,提出“负荷备用分省预留、事故备用全网共享”的分区备用留取模式,并分析负荷负备用的必要性;最后,基于区域电网辅助服务市场机制,考虑新能源不确定性和事故N-1的备用调用场景约束,设计区域电网的电能与备用联合优化流程。

关键词：区域电网备用容量新能源 N-1安全新型电力系统

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青少年非自杀性自伤行为自我表露的研究进展

中华精神科杂志 2022年第1期55卷 69-72页

作者：丁强孙锦华复旦大学附属儿科医院心理科上海201102

非自杀性自伤行为(non-suicidal self-injury,NSSI)是青少年中高发且严重的公共卫生问题,但有研究发现青少年经常会隐瞒NSSI。自我表露是指个体把自己的有关信息向他人传递的行为,个体表露自己实施NSSI可能为获得支持和帮助提供重要机... 详细信息

非自杀性自伤行为(non-suicidal self-injury,NSSI)是青少年中高发且严重的公共卫生问题,但有研究发现青少年经常会隐瞒NSSI。自我表露是指个体把自己的有关信息向他人传递的行为,个体表露自己实施NSSI可能为获得支持和帮助提供重要机会。本文对青少年NSSI自我表露率、自我表露对象、促进或阻碍自我表露的因素、自我表露的作用和影响进行综述,以期为未来相关的临床实践和研究提供理论依据。

关键词：自杀自我伤害行为青少年自我表露

Multi-region calcium imaging in freely behaving mice with ultra-compact head-mounted fluorescence microscopes

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National Science Review 2024年第1期11卷 161-173页

作者： Feng Xue Fei Li Ke-ming Zhang Lufeng ding Yang Wang Xingtao Zhao Fang Xu Danke Zhang Mingzhai Sun Pak-Ming Lau Qingyuan Zhu Pengcheng Zhou Guo-qiang Bi Department of Precision Machinery and Precision Instruments University of Science and Technology of China Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of China Interdisciplinary Center for Brain Information the Brain Cognition and Brain Disease Institute Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Faculty of Life and Health Sciences Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences School of Life Sciences University of Science and Technology of China Institute of Semiconductors Chinese Academy of Sciences Department of Modern Life Sciences and Biotecnology Xiongan Institute of Innovation Xiongan New Area Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions Suzhou Institute for Advanced Research University of Science and Technology of China Institute of Artiflcial Intelligence Hefei Comprehensive National Science Center

To investigate the circuit-level neural mechanisms of behavior, simultaneous imaging of neuronal activity in multiple cortical and subcortical regions is highly desired. Miniature head-mounted microscopes offer the capability of calcium imaging in freely behaving animals. However, implanting multiple microscopes on a mouse brain remains challenging due to space constraints and the cumbersome weight of the ***, we present TINIscope, a Tightly Integrated Neuronal Imaging microscope optimized for electronic and opto-mechanical design. With its compact and lightweight design of 0.43 g, TINIscope enables unprecedented simultaneous imaging of behavior-relevant activity in up to four brain regions in ***-of-concept experiments with TINIscope recorded over 1000 neurons in four hippocampal subregions and revealed concurrent activity patterns spanning across these regions. Moreover, we explored potential multi-modal experimental designs by integrating additional modules for optogenetics, electrical stimulation or local field potential recordings. Overall, TINIscope represents a timely and indispensable tool for studying the brain-wide interregional coordination that underlies unrestrained behaviors.

关键词： miniature microscope multiple sites calcium imaging multimodal integration hippocampus

N-acetylcysteine ameliorates erectile dysfunction in rats with hyperlipidemia by inhibiting oxidative stress and corpus cavernosum smooth muscle cells phenotypic modulation

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Asian Journal of Andrology 2024年第1期26卷 99-106页

作者： Wei ding Jun-Hong Fan Li-Ren Zhong Nan-Xiong Wang Lu-Hao Liu Hai-Bo Zhang Li Wang Ming-qiang Wang Bing-Lin He An-Yang Wei Department of Urology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang 550002China Department of Urology Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhou 510000China Department of Urology Nanfang HospitalSouthern Medical UniversityGuangzhou 510000China Department of Urology Shenzhen Immigration Inspection General Station HospitalShenzhen 518000China Department of Organ Transplantation The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang 550002China

Hyperlipidemia is a major risk factor for erectile dysfunction(ED).Oxidative stress and phenotypic modulation of corpus cavernosum smooth muscle cells(CcSMCs)are the key pathological factors of ED.N-acetylcysteine(NAC)can inhibit oxidative stress;however,whether NAc can alleviate pathological variations in the corpus cavernosum and promote erectile function recovery in hyperlipidemic rats remains unclear.A hyperlipidemia model was established using 27 eight-week-old male Sprague-Dawley(SD)rats fed a high-fat and high-cholesterol diet(hyperlipidemic rats,HR).In addition,9 male SD rats were fed a normal diet to serve as controls(NC).HR rats were divided into three groups:HR,HR+normal saline(NS),and HR+NAC(n=9 for each group;NS or NAc intraperitoneal injections were administered daily for 16 weeks).Subsequently,the lipid profiles,erectile function,oxidative stress,phenotypic modulation markers of ccsMCs,and tissue histology were *** experimental results revealed that erectile function was significantly impaired in the HR and HR+NS groups,but enhanced in the HR+NAC *** lipid levels,over-activated oxidative stress,and multi-organ lesions observed in the HR and HR+NS groups were improved in the HR+NAC ***,the HR group showed significant phenotypic modulation of CCSMCs,which was also inhibited by NAC *** report focuses on the therapeutic effect of NAc in restoring erectile function using a hyperlipidemic rat model by preventing CcSMC phenotypic modulationand attenuating oxidativestress.

关键词： erectile dysfunction hyperlipidemia N-acetylcysteine oxidative stress henotypic modulation

Molecular dynamics simulations on the interactions between nucleic acids and a phospholipid bilayer

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Chinese Physics B 2024年第2期33卷 512-521页

作者：徐耀黄舒伟丁泓铭马余强 National Laboratory of Solid State Microstructures and Department of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China Center for Soft Condensed Matter Physics and Interdisciplinary Research School of Physical Science and TechnologySoochow UniversitySuzhou 215006China

Recently,lipid nanoparticles(LNPs)have been extensively investigated as non-viral carriers of nucleic acid vaccines due to their high transport efficiency,safety,and straightforward production and ***,the molecular mechanism underlying the interactions between nucleic acids and phospholipid bilayers within LNPs remains *** this study,we employed the all-atom molecular dynamics simulation to investigate the interactions between single-stranded nucleic acids and a phospholipid *** findings revealed that hydrophilic bases,specifically G in single-stranded RNA(ssRNA)and single-stranded DNA(ssDNA),displayed a higher propensity to form hydrogen bonds with phospholipid head ***,ssRNA exhibited stronger binding energy than ***,divalent ions,particularly Ca2+,facilitated the binding of ssRNA to phospholipids due to their higher binding energy and lower dissociation rate from ***,our study provides valuable insights into the molecular mechanisms underlying nucleic acidphospholipid interactions,with potential implications for the nucleic acids in biotherapies,particularly in the context of lipid carriers.

关键词： RNA DNA lipid bilayer molecular dynamics interface interaction divalent cation

“组团式”对口支援的发生逻辑与维持机制--以J省医疗援K为例

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湖南科技大学学报（社会科学版） 2023年第6期26卷 83-89页

作者：黄亚新丁强南京医科大学医政学院

在我国政治、制度和文化优势的合力推动下,传统府际对口支援发生了一场自我进化,形成了“组团式”对口支援新模式。“组团式”对口支援能够持续存在的原因是其拥有一套关系维持机制,包括“硬法授权”与“软法规约”相互包容下形成的稳... 详细信息

在我国政治、制度和文化优势的合力推动下,传统府际对口支援发生了一场自我进化,形成了“组团式”对口支援新模式。“组团式”对口支援能够持续存在的原因是其拥有一套关系维持机制,包括“硬法授权”与“软法规约”相互包容下形成的稳定权力关系,“政绩共求”与“技艺共需”相互博弈下形成的稳定利益关系,“社会情感”与“个体情感”相互承诺下形成的稳定情感关系。面向未来,“组团式”对口支援需要吸纳社会力量、尝试市场介入、运用数智技术、坚持久久为功,但同时要注意与市民社会进行区分、规导资本趋利本性、防范智能异化风险,避免陷入帮扶依赖,最大程度挖掘“小组团”所潜藏的大能量。

关键词：组团式对口支援发生逻辑维持机制

Improvement in hydrogen storage performance of MgH_(2) by vanadium doped with ZIF-8 derived a single-atom catalyst V-N-C

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Rare Metals 2024年第6期43卷 2623-2635页

作者： Fei-Fan Hong Wei-Tao Shi Ruo-Lin Zhao Yi Fan Zi-Qi Liu Si-Zhi ding Hai-Zhen Liu Wen-Zheng Zhou Jin Guo Zhi-qiang Lan Guangxi Novel Battery Materials Research Center of Engineering Technology and Center on Nanoenergy Research Guangxi Colleges and Universities Key Laboratory of Blue Energy and Systems IntegrationCarbon Peak and Neutrality Science and Technology Development InstituteSchool of Physical Science and TechnologyGuangxi UniversityNanning 530004China Nanning Engineering Technology Research Center for Power Transmission System of New Energy Vehicle Transportation CollegeNanning UniversityNanning 530200China

Herein,the successful preparation of a singleatom catalyst V-N-C using vanadium-doped zeolitic imidazolate framework(ZIF)-8 as a precursor is *** experimental results showed that the V-N-C had a good promoting effect on the hydrogen storage performance of MgH_(2),and the optimal addition amount of V-N-C was 10wt%.The hydrogenation and dehydrogenation apparent activation energies of 10 wt%V-N-C-catalyzed MgH_(2)were reduced by 44.9 and 53.5 kJ·mol^(-1),respectively,compared to those of additive-free MgH_(2).The 10 wt%V-N-C-catalyzed MgH_(2)could reabsorb 5.92 wt%of hydrogen in 50 min at 150℃,with a capacity retention rate of 99.1%after 30 cycles of hydrogen absorption and *** analysis showed that V-N-C was partially transformed into VN and metallic V when it was milled with MgH_(2);the in-situ-formed VN and metallic V played an important role in improving the hydrogen storage performance of MgH_(2).This approach provides a potential solution for obtaining high-performance Mg-based hydrogen storage materials through synergistic interactions between V,N and C.

关键词： MgH_(2) Hydrogen storage materials Catalyst Hydrogen storage perormance